ar-c239 has been researched along with yohimbine in 14 studies
| Studies (ar-c239) | Trials (ar-c239) | Recent Studies (post-2010) (ar-c239) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 45 | 0 | 5 | 5,893 | 253 | 532 |
| Protein | Taxonomy | ar-c239 (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biagini, P; Biancalani, C; Cesari, N; Dal Piaz, V; Galeotti, N; Ghelardini, C; Giovannoni, MP; Graziano, A; Vergelli, C | 1 |
| Bylund, DB; Ray-Prenger, C | 1 |
| Bousquet, P; Feldman, J | 1 |
| Bylund, DB; Petterborg, LJ; Ray-Prenger, C; Rudeen, PK | 1 |
| Haigler, HJ; O'Neill, TP | 1 |
| Mouillé, P; Schmitt, H | 1 |
| Musgrave, IF; Seifert, R | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Coupar, IM; Liu, L | 1 |
| Goepel, M; Michel, MC; Rübben, H; Wittmann, A | 1 |
| Akaike, N; Arima, J; Ishibashi, H; Kubo, C | 1 |
| Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Centurión, D; Hofmann, RA; Jantschak, F; Pertz, HH; Popp, AM; Villalón, CM | 1 |
14 other study(ies) available for ar-c239 and yohimbine
| Article | Year |
|---|---|
Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action.
Topics: Abdominal Muscles; Abdominal Pain; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Cerebral Cortex; Norepinephrine; Pyridazines; Rats; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Synaptosomes; Yohimbine | 2006 |
Alpha-2A and alpha-2B adrenergic receptor subtypes: attenuation of cyclic AMP production in cell lines containing only one receptor subtype.
Topics: Animals; Brimonidine Tartrate; Cyclic AMP; Humans; Isoquinolines; Piperazines; Prazosin; Quinoxalines; Rats; Receptors, Adrenergic, alpha; Tumor Cells, Cultured; Yohimbine | 1989 |
The blood pressure effects of alpha-adrenoceptor antagonists injected in the medullary site of action of clonidine: the nucleus reticularis lateralis.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Dioxanes; Female; Idazoxan; Isoquinolines; Male; Medulla Oblongata; Piperazines; Prazosin; Yohimbine | 1987 |
Identification of alpha 2-adrenergic receptors in chicken pineal gland using [3H]rauwolscine.
Topics: Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane; Chickens; Circadian Rhythm; Female; Isoquinolines; Male; Pindolol; Pineal Gland; Piperazines; Quinoxalines; Receptors, Adrenergic, alpha; Tritium; Yohimbine | 1988 |
Effects of clonidine on neuronal firing evoked by a noxious stimulus.
Topics: Animals; Clonidine; Electrophysiology; Isoquinolines; Male; Neurons; Norepinephrine; Pain; Physical Stimulation; Piperazines; Piperoxan; Rats; Rats, Inbred Strains; Stimulation, Chemical; Yohimbine | 1985 |
[Nature of alpha receptors implicated in the hypertensive effect of high doses of isoprenaline in dogs and rats].
Topics: Animals; Blood Pressure; Dogs; Female; Isoproterenol; Isoquinolines; Male; Piperazines; Rats; Receptors, Adrenergic, alpha; Stimulation, Chemical; Yohimbine | 1984 |
Alpha 2A-adrenoceptors mediate activation of non-selective cation channels via Gi-proteins in human erythroleukaemia (HEL) cells. No evidence for a functional role of imidazoline receptors in modulating calcium.
Topics: Binding, Competitive; Calcium; Cell Fractionation; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Imidazoline Receptors; Ion Channels; Isoquinolines; Leukemia, Erythroblastic, Acute; Oxymetazoline; Pertussis Toxin; Piperazines; Receptors, Adrenergic, alpha; Receptors, Drug; Tumor Cells, Cultured; Virulence Factors, Bordetella; Yohimbine | 1995 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
Role of alpha 2-adrenoceptors in the regulation of intestinal water transport.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Transport; Brimonidine Tartrate; Dose-Response Relationship, Drug; Female; Ileum; Imidazoles; Indoles; Intestinal Absorption; Isoindoles; Isoquinolines; Jejunum; Male; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasoactive Intestinal Peptide; Water; Yohimbine | 1997 |
Comparison of adrenoceptor subtype expression in porcine and human bladder and prostate.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Female; Humans; Imidazoles; Isoquinolines; Male; Oxymetazoline; Piperazines; Prazosin; Propanolamines; Prostate; Radioligand Assay; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Swine; Urinary Bladder; Yohimbine | 1997 |
alpha2-Adrenoceptor-mediated potassium currents in acutely dissociated rat locus coeruleus neurones.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Cell Membrane Permeability; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Isoquinolines; Kinetics; Locus Coeruleus; Membrane Potentials; Neurons; Nystatin; Patch-Clamp Techniques; Piperazines; Potassium; Potassium Channel Blockers; Potassium Channels; Prazosin; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Thionucleotides; Yohimbine | 1998 |
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine | 1999 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Imidazoles; In Vitro Techniques; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Piperazines; Prazosin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Serotonin; Tail; Temperature; Vasoconstriction; Yohimbine | 2010 |