Page last updated: 2024-09-03

ar-c239 and guanfacine

ar-c239 has been researched along with guanfacine in 2 studies

Compound Research Comparison

Studies (ar-c239)	Trials (ar-c239)	Recent Studies (post-2010) (ar-c239)	Studies (guanfacine)	Trials (guanfacine)	Recent Studies (post-2010) (guanfacine)
45	0	5	784	180	273

Protein Interaction Comparison

Protein	Taxonomy	guanfacine (IC50)
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	1.453
Alpha-2A adrenergic receptor	Homo sapiens (human)	0.134
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.249
Alpha-2C adrenergic receptor	Homo sapiens (human)	6.447
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	3.014
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	1.453
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	2.098

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Uhlén, S; Wikberg, JE	1
Bobirnac, I; Gazi, L; Loetscher, E; Parsley, S; Schoeffter, P	1

Other Studies

2 other study(ies) available for ar-c239 and guanfacine

Article	Year
Delineation of rat kidney alpha 2A- and alpha 2B-adrenoceptors with [3H]RX821002 radioligand binding: computer modelling reveals that guanfacine is an alpha 2A-selective compound. European journal of pharmacology, 1991, Sep-17, Volume: 202, Issue:2 Topics: Animals; Computer Simulation; Dioxanes; Guanfacine; Idazoxan; In Vitro Techniques; Isoquinolines; Kidney; Male; Monte Carlo Method; Piperazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha	1991
Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells. European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1 Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine	1999

Article

Year

Delineation of rat kidney alpha 2A- and alpha 2B-adrenoceptors with [3H]RX821002 radioligand binding: computer modelling reveals that guanfacine is an alpha 2A-selective compound.

European journal of pharmacology, 1991, Sep-17, Volume: 202, Issue:2

Topics: Animals; Computer Simulation; Dioxanes; Guanfacine; Idazoxan; In Vitro Techniques; Isoquinolines; Kidney; Male; Monte Carlo Method; Piperazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1991

Functional alpha2C-adrenoceptors in human neuroblastoma SH-SY5Y cells.

European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Brimonidine Tartrate; Clonidine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Humans; Idazoxan; Isoquinolines; Neuroblastoma; Oxymetazoline; Piperazines; Prazosin; Quinoxalines; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Yohimbine

1999