ar-c239 has been researched along with brl 44408 in 18 studies
| Studies (ar-c239) | Trials (ar-c239) | Recent Studies (post-2010) (ar-c239) | Studies (brl 44408) | Trials (brl 44408) | Recent Studies (post-2010) (brl 44408) |
|---|---|---|---|---|---|
| 45 | 0 | 5 | 82 | 0 | 16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biagini, P; Biancalani, C; Cesari, N; Dal Piaz, V; Galeotti, N; Ghelardini, C; Giovannoni, MP; Graziano, A; Vergelli, C | 1 |
| García-Sevilla, JA; Sastre, M | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Bencsics, A; Elenkov, IJ; Vizi, ES | 1 |
| Callado, LF; García-Sevilla, JA; Grijalba, B; Meana, JJ; Pazos, A | 1 |
| Esteban, S; García-Sevilla, JA; Lladó, J | 1 |
| Coupar, IM; Liu, L | 1 |
| Callado, LF; Stamford, JA | 1 |
| Callado, LF; Gabilondo, AM; Meana, JJ | 1 |
| Mateo, Y; Meana, JJ | 1 |
| Chotani, MA; Daunt, D; Flavahan, NA; Flavahan, S; Mitra, S | 1 |
| Adachi, YU; Satoh, T; Taoda, M; Uchihashi, Y; Vizi, ES; Watanabe, K | 1 |
| Hopwood, SE; Stamford, JA | 1 |
| Centurión, D; Görnemann, T; Jähnichen, S; Kleuser, B; Pertz, HH; Villalón, CM; von Wenckstern, H | 1 |
| Benvenuti, E; Fang, Y; Ferrie, A; Hong, Y; Lai, F; Lui, L; Miret, J; Nettleton, D; Posner, B; Potchoiba, M; Webb, B; Wielis, C | 1 |
| Ducza, E; Falkay, G; Gál, A; Gálik, M; Gáspár, R; Klukovits, A; Kolarovszki-Sipiczki, Z; Minorics, R | 1 |
| Centurión, D; Hofmann, RA; Jantschak, F; Pertz, HH; Popp, AM; Villalón, CM | 1 |
| Aoyama, B; Kawano, T; Locatelli, FM; Nishigaki, A; Shigematsu-Locatelli, M; Tateiwa, H; Yamanaka, D; Yokoyama, M | 1 |
18 other study(ies) available for ar-c239 and brl 44408
| Article | Year |
|---|---|
Arylpiperazinylalkylpyridazinones and analogues as potent and orally active antinociceptive agents: synthesis and studies on mechanism of action.
Topics: Abdominal Muscles; Abdominal Pain; Administration, Oral; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Cerebral Cortex; Norepinephrine; Pyridazines; Rats; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Synaptosomes; Yohimbine | 2006 |
Alpha 2-adrenoceptor subtypes identified by [3H]RX821002 binding in the human brain: the agonist guanoxabenz does not discriminate different forms of the predominant alpha 2A subtype.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Binding, Competitive; Brain; Dioxanes; Edetic Acid; Female; Guanabenz; Guanylyl Imidodiphosphate; Humans; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Piperazines; Receptors, Adrenergic, alpha; Sodium Chloride; Tritium | 1994 |
Determination on functional basis of presynaptic alpha 2-adrenoceptor subtypes in guinea-pig duodenum.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cholinergic Fibers; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Medetomidine; Muscle Contraction; Nordefrin; Norepinephrine; Oxymetazoline; Piperazines; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Membranes; Vasoconstrictor Agents; Xylazine; Yohimbine | 1996 |
alpha 2-, alpha 2A-, alpha 2B/2C-Adrenoceptor subtype antagonists prevent lipopolysaccharide-induced fever response in rabbits.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Body Temperature; Dioxanes; Fever; Imidazoles; Indoles; Injections, Intravenous; Isoindoles; Isoquinolines; Lipopolysaccharides; Male; Piperazines; Prazosin; Rabbits; Receptors, Adrenergic, alpha-2; Skin Physiological Phenomena | 1995 |
The subtype-selective alpha 2-adrenoceptor antagonists BRL 44408 and ARC 239 also recognize 5-HT1A receptors in the rat brain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Brain; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin | 1996 |
Alpha 2-autoreceptors and alpha 2-heteroreceptors modulating tyrosine and tryptophan hydroxylase activity in the rat brain in vivo: an investigation into the alpha 2-adrenoceptor subtypes.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Brain; Cerebral Cortex; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hippocampus; Histamine H1 Antagonists; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Mianserin; Mirtazapine; Norepinephrine; Piperazines; Quinolines; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1996 |
Role of alpha 2-adrenoceptors in the regulation of intestinal water transport.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Transport; Brimonidine Tartrate; Dose-Response Relationship, Drug; Female; Ileum; Imidazoles; Indoles; Intestinal Absorption; Isoindoles; Isoquinolines; Jejunum; Male; Piperazines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Vasoactive Intestinal Peptide; Water; Yohimbine | 1997 |
Alpha2A- but not alpha2B/C-adrenoceptors modulate noradrenaline release in rat locus coeruleus: voltammetric data.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Electric Stimulation; Electrochemistry; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Medetomidine; Norepinephrine; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Adrenergic, alpha-2 | 1999 |
Differential modulation of alpha2-adrenoceptor subtypes in rat kidney by chronic desipramine treatment.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Clorgyline; Desipramine; Epinephrine; Idazoxan; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney; Kinetics; Male; Monoamine Oxidase Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2 | 1999 |
Determination of the somatodendritic alpha2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Brimonidine Tartrate; Cerebral Cortex; Chromatography, High Pressure Liquid; Clonidine; Dendritic Cells; Drug Interactions; Idazoxan; Imidazoles; Indoles; Isoindoles; Isoquinolines; Locus Coeruleus; Male; Microdialysis; Norepinephrine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Time Factors | 1999 |
Silent alpha(2C)-adrenergic receptors enable cold-induced vasoconstriction in cutaneous arteries.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Body Temperature Regulation; Brimonidine Tartrate; Cold Temperature; COS Cells; Imidazoles; Indoles; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Microcirculation; Muscle, Smooth, Vascular; Organ Culture Techniques; Phenylephrine; Piperazines; Quinolizines; Quinoxalines; Raynaud Disease; Receptors, Adrenergic, alpha-2; Scleroderma, Systemic; Skin; Tail; Vasoconstriction | 2000 |
Effect of dexmedetomidine on the release of [3H]-noradrenaline from rat kidney cortex slices: characterization of alpha2-adrenoceptor.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Berberine; Chromatography, High Pressure Liquid; Dexmedetomidine; Dose-Response Relationship, Drug; Feedback; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Kidney Cortex; Male; Morphine; Norepinephrine; Piperazines; Prazosin; Prednisone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tritium | 2001 |
Noradrenergic modulation of serotonin release in rat dorsal and median raphé nuclei via alpha(1) and alpha(2A) adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Desipramine; Dexmedetomidine; Electric Stimulation; Electrophysiology; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Male; Norepinephrine; Phenylephrine; Piperazines; Prazosin; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Serotonin | 2001 |
Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brimonidine Tartrate; Clonidine; Dioxanes; Dose-Response Relationship, Drug; Gene Expression; Imidazoles; In Vitro Techniques; Indoles; Isoindoles; Isoquinolines; Neuromuscular Junction; Norepinephrine; Piperazines; Prazosin; Pulmonary Veins; Quinolizines; Quinoxalines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Vasoconstriction; Yohimbine | 2007 |
Multiplexing G protein-coupled receptors in microarrays: a radioligand-binding assay.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Line; Clonidine; Cricetinae; Humans; Imidazoles; Indoles; Isoindoles; Isoquinolines; Piperazines; Protein Array Analysis; Protein Binding; Radioligand Assay; Receptors, Adrenergic; Receptors, G-Protein-Coupled | 2007 |
Different roles of alpha2-adrenoceptor subtypes in non-pregnant and late-pregnant uterine contractility in vitro in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blotting, Western; Cyclic AMP; Dioxanes; Female; Imidazoles; In Vitro Techniques; Isoindoles; Isoquinolines; Labor, Induced; Mifepristone; Myometrium; Norepinephrine; Piperazines; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reverse Transcriptase Polymerase Chain Reaction; Spiro Compounds; Uterine Contraction | 2007 |
Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Brimonidine Tartrate; Dioxanes; Imidazoles; In Vitro Techniques; Isoindoles; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Piperazines; Prazosin; Quinolizines; Quinoxalines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Serotonin; Tail; Temperature; Vasoconstriction; Yohimbine | 2010 |
Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats.
Topics: Aging; Animals; Cognitive Dysfunction; Dexmedetomidine; Hippocampus; Hypnotics and Sedatives; Imidazoles; Inflammation; Isoindoles; Isoquinolines; Lipopolysaccharides; Male; Memory Disorders; Neuroprotective Agents; Piperazines; Rats; Signal Transduction | 2017 |