Page last updated: 2024-09-03

ar 12463 and trapidil

ar 12463 has been researched along with trapidil in 14 studies

Compound Research Comparison

Studies
(ar 12463)
Trials
(ar 12463)
Recent Studies (post-2010)
(ar 12463)
Studies
(trapidil)
Trials
(trapidil)
Recent Studies (post-2010) (trapidil)
14002992525

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19908 (57.14)18.7374
1990's6 (42.86)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fahr, F; Hahn, HJ; Neubert, R; Pönicke, K1
Beitz, A; Beitz, J; Krüger, J; Mest, HJ; Pawelski, K; Rath, FW; Szymanski, C1
Grahlmann, D; Langner, A; Pfeifer, S1
Beitz, J; Bellosta, S; Bernini, F; Corsini, A; Fumagalli, R; Mest, HJ; Paoletti, R1
Franke, P; Grahlmann, D; Gründemann, E; Langner, A; Pfeifer, S; Tenor, E1
Grahlmann, D; Langner, A; Nerlich, C1
Markwardt, F; Nilius, B1
Beitz, A; Beitz, J; Goos, H; Graff, J; Lindenau, KF; Mest, HJ; Nohring, J; Taube, C1
Beitz, J; Corsini, A; Fumagalli, R; Granata, A; Mest, HJ; Paoletti, R1
Block, HU; Gabbasov, ZA; Mest, HJ; Popov, EG; Pozin, EY1
Block, HU; Dunemann, A; Mest, HJ; Niebisch, M1
Hauser, A; Heinroth-Hoffmann, I; Mest, HJ; Taube, C1
Mest, HJ; Steinborn, C; Taube, C2

Other Studies

14 other study(ies) available for ar 12463 and trapidil

ArticleYear
[Improvement of the disolution behavior of problem drugs. 22. Preformulations of AR 12463 in absorption models].
    Die Pharmazie, 1991, Volume: 46, Issue:9

    Topics: Chemistry, Pharmaceutical; Solubility; Trapidil

1991
Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits.
    Biomedica biochimica acta, 1991, Volume: 50, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Electrophoresis, Polyacrylamide Gel; Hypercholesterolemia; Kidney; Kinetics; Lipid Metabolism; Lipids; Liver; Rabbits; Trapidil

1991
[Comparison of the biotransformation of the trapidil (Rocornal) derivative AR 12463 in humans, rats, dogs, and rabbits].
    Die Pharmazie, 1991, Volume: 46, Issue:3

    Topics: Animals; Biotransformation; Dogs; Feces; Humans; Rabbits; Rats; Species Specificity; Trapidil

1991
Influence of trapidil and derivatives on cholesterol synthesis and esterification in cultured cells.
    Pharmacological research, 1991, Volume: 24, Issue:3

    Topics: Acetates; Cells, Cultured; Cholesterol; Cholesterol Esters; Esterification; Fibroblasts; Humans; Macrophages; Mevalonic Acid; Trapidil; Tumor Cells, Cultured

1991
[Biotransformation of the trapidil (rocornal) derivative AR 12463 in the rat].
    Die Pharmazie, 1990, Volume: 45, Issue:8

    Topics: Adsorption; Animals; Biotransformation; Chromatography, Thin Layer; Feces; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Trapidil

1990
[Biotransformation of the trapidil (Rocornal) derivative AR 12,463 by the isolated, perfused rat liver and rat hepatocyte suspension cultures].
    Die Pharmazie, 1990, Volume: 45, Issue:8

    Topics: Animals; Cells, Cultured; In Vitro Techniques; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trapidil

1990
Effects of trapidil-derivatives on calcium channel currents in isolated ventricular cells from mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:4

    Topics: Animals; Female; Heart; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mice; Myocardium; Pyrimidines; Trapidil

1988
Influence of drugs on the TXA2/PGI2 balance and on the atherogenic index in myocardial ischemia in dogs.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Coronary Disease; Dogs; Epoprostenol; Female; Iloprost; Male; Pyrimidines; Reference Values; Thromboxane A2; Trapidil

1988
Effect of derivatives of trapidil on the expression of LDL receptors.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Antihypertensive Agents; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Humans; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Pyrimidines; Receptors, LDL; Skin; Trapidil

1988
Inhibition of cytosolic Ca++ mobilization in human platelets by the antianginal drug trapidil and its derivative AR 12463.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antihypertensive Agents; Blood Platelets; Calcium; Cytosol; Humans; In Vitro Techniques; Kinetics; Phosphoric Diester Hydrolases; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Thromboxanes; Trapidil

1988
Influence of the antianginal drug trapidil and its derivative AR 12463 on arachidonic acid liberation and thromboxane formation in thrombin-stimulated platelets.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Antihypertensive Agents; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Pyrimidines; Thrombin; Thromboxanes; Trapidil

1988
Effects of trapidil and trapidil derivatives on arachidonic acid and prostaglandin endoperoxide analogue U 46619-induced blood pressure changes in rats.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Male; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Thromboxane B2; Trapidil

1988
Trapidil derivative AR 12463 lowers blood pressure and thromboxane formation in spontaneously hypertensive rats.
    Progress in clinical and biological research, 1987, Volume: 242

    Topics: Animals; Aorta; Blood Pressure; Male; Muscle, Smooth, Vascular; Pyrimidines; Rats; Rats, Inbred SHR; Thromboxanes; Trapidil

1987
[The effect of trapidil and the trapidil derivative AR 12463 on blood pressure and thromboxane formation in spontaneously hypertensive rats].
    Die Pharmazie, 1987, Volume: 42, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Heart Rate; Male; Pyrimidines; Rats; Rats, Inbred SHR; Thromboxane B2; Trapidil

1987