ar 12463 has been researched along with trapidil in 14 studies
| Studies (ar 12463) | Trials (ar 12463) | Recent Studies (post-2010) (ar 12463) | Studies (trapidil) | Trials (trapidil) | Recent Studies (post-2010) (trapidil) |
|---|---|---|---|---|---|
| 14 | 0 | 0 | 299 | 25 | 25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fahr, F; Hahn, HJ; Neubert, R; Pönicke, K | 1 |
| Beitz, A; Beitz, J; Krüger, J; Mest, HJ; Pawelski, K; Rath, FW; Szymanski, C | 1 |
| Grahlmann, D; Langner, A; Pfeifer, S | 1 |
| Beitz, J; Bellosta, S; Bernini, F; Corsini, A; Fumagalli, R; Mest, HJ; Paoletti, R | 1 |
| Franke, P; Grahlmann, D; Gründemann, E; Langner, A; Pfeifer, S; Tenor, E | 1 |
| Grahlmann, D; Langner, A; Nerlich, C | 1 |
| Markwardt, F; Nilius, B | 1 |
| Beitz, A; Beitz, J; Goos, H; Graff, J; Lindenau, KF; Mest, HJ; Nohring, J; Taube, C | 1 |
| Beitz, J; Corsini, A; Fumagalli, R; Granata, A; Mest, HJ; Paoletti, R | 1 |
| Block, HU; Gabbasov, ZA; Mest, HJ; Popov, EG; Pozin, EY | 1 |
| Block, HU; Dunemann, A; Mest, HJ; Niebisch, M | 1 |
| Hauser, A; Heinroth-Hoffmann, I; Mest, HJ; Taube, C | 1 |
| Mest, HJ; Steinborn, C; Taube, C | 2 |
14 other study(ies) available for ar 12463 and trapidil
| Article | Year |
|---|---|
[Improvement of the disolution behavior of problem drugs. 22. Preformulations of AR 12463 in absorption models].
Topics: Chemistry, Pharmaceutical; Solubility; Trapidil | 1991 |
Influence of the trapidil derivative AR 12463 on serum and tissue lipids and development of aortic lesions during experimental atherosclerosis in rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Electrophoresis, Polyacrylamide Gel; Hypercholesterolemia; Kidney; Kinetics; Lipid Metabolism; Lipids; Liver; Rabbits; Trapidil | 1991 |
[Comparison of the biotransformation of the trapidil (Rocornal) derivative AR 12463 in humans, rats, dogs, and rabbits].
Topics: Animals; Biotransformation; Dogs; Feces; Humans; Rabbits; Rats; Species Specificity; Trapidil | 1991 |
Influence of trapidil and derivatives on cholesterol synthesis and esterification in cultured cells.
Topics: Acetates; Cells, Cultured; Cholesterol; Cholesterol Esters; Esterification; Fibroblasts; Humans; Macrophages; Mevalonic Acid; Trapidil; Tumor Cells, Cultured | 1991 |
[Biotransformation of the trapidil (rocornal) derivative AR 12463 in the rat].
Topics: Adsorption; Animals; Biotransformation; Chromatography, Thin Layer; Feces; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Trapidil | 1990 |
[Biotransformation of the trapidil (Rocornal) derivative AR 12,463 by the isolated, perfused rat liver and rat hepatocyte suspension cultures].
Topics: Animals; Cells, Cultured; In Vitro Techniques; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Trapidil | 1990 |
Effects of trapidil-derivatives on calcium channel currents in isolated ventricular cells from mice.
Topics: Animals; Female; Heart; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mice; Myocardium; Pyrimidines; Trapidil | 1988 |
Influence of drugs on the TXA2/PGI2 balance and on the atherogenic index in myocardial ischemia in dogs.
Topics: Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Coronary Disease; Dogs; Epoprostenol; Female; Iloprost; Male; Pyrimidines; Reference Values; Thromboxane A2; Trapidil | 1988 |
Effect of derivatives of trapidil on the expression of LDL receptors.
Topics: Antihypertensive Agents; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Humans; Kinetics; Lipoproteins, LDL; Liver Neoplasms; Pyrimidines; Receptors, LDL; Skin; Trapidil | 1988 |
Inhibition of cytosolic Ca++ mobilization in human platelets by the antianginal drug trapidil and its derivative AR 12463.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Antihypertensive Agents; Blood Platelets; Calcium; Cytosol; Humans; In Vitro Techniques; Kinetics; Phosphoric Diester Hydrolases; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Thromboxanes; Trapidil | 1988 |
Influence of the antianginal drug trapidil and its derivative AR 12463 on arachidonic acid liberation and thromboxane formation in thrombin-stimulated platelets.
Topics: Antihypertensive Agents; Arachidonic Acids; Blood Platelets; Humans; In Vitro Techniques; Kinetics; Pyrimidines; Thrombin; Thromboxanes; Trapidil | 1988 |
Effects of trapidil and trapidil derivatives on arachidonic acid and prostaglandin endoperoxide analogue U 46619-induced blood pressure changes in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Aspirin; Blood Pressure; Calcium Channel Blockers; Male; Prostaglandin Endoperoxides, Synthetic; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Thromboxane B2; Trapidil | 1988 |
Trapidil derivative AR 12463 lowers blood pressure and thromboxane formation in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Male; Muscle, Smooth, Vascular; Pyrimidines; Rats; Rats, Inbred SHR; Thromboxanes; Trapidil | 1987 |
[The effect of trapidil and the trapidil derivative AR 12463 on blood pressure and thromboxane formation in spontaneously hypertensive rats].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Heart Rate; Male; Pyrimidines; Rats; Rats, Inbred SHR; Thromboxane B2; Trapidil | 1987 |