aptiganel has been researched along with n-methylaspartate in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, CR; Jung, DS; Kang, JK; McCulloch, J; Park, CK | 1 |
| McBurney, RN | 1 |
| Barber, PA; Buchan, AM; Hill, MD; Hoyte, L | 1 |
| Aronowski, J; Grotta, JC; Palusinski, R; Piriyawat, P; Strong, R; Zhao, X | 1 |
2 review(s) available for aptiganel and n-methylaspartate
| Article | Year |
|---|---|
Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury.
Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries | 1997 |
The rise and fall of NMDA antagonists for ischemic stroke.
Topics: Animals; Brain Ischemia; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Antagonists; Guanidines; Humans; Indoles; Ischemia; N-Methylaspartate; Neurons; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Stroke | 2004 |
2 other study(ies) available for aptiganel and n-methylaspartate
| Article | Year |
|---|---|
Do N-methyl-D-aspartate antagonists have disproportionately greater effects on brain swelling than on ischemic damage in focal cerebral infarction?
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cerebral Infarction; Extracellular Space; Guanidines; Male; N-Methylaspartate; Piperazines; Rats; Rats, Sprague-Dawley | 1994 |
Caffeinol at the receptor level: anti-ischemic effect of N-methyl-D-aspartate receptor blockade is potentiated by caffeine.
Topics: Animals; Brain Ischemia; Caffeine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Guanidines; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors; Treatment Outcome | 2010 |