aprofen has been researched along with atropine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, PK; Doctor, BP; Gordon, RK; Leader, H; Padilla, FN; Payne, CS; Smejkal, RM | 1 |
| Abraham, P; Ahmad, A; Carroll, FI; Chiang, PK; Griffith, RC; Padilla, FN; Parham, K; Richard, MM; Witkin, JM | 1 |
| Chiang, PK; Gordon, RK; Leader, H; Wolfe, AD | 1 |
| Bhattacharjee, AK; Campbell, A; Gordon, JA; Gordon, RK; Marek, E | 1 |
| Bhattacharjee, AK; Evans, SA; Gordon, RK; Pervitsky, D; Pomponio, JW | 1 |
| Elsmore, TF; Genovese, RF; Witkin, JM | 1 |
| Chiang, PK; Covington, J; Jackson, BW; Leader, H; Newman, AH; Oleshansky, M; Weissman, BA | 1 |
| Domino, EF; Head, R; Pohorecki, R | 1 |
| Dawson, RM; Freeman, SE; Paddle, BM | 1 |
| Inns, RH; Leadbeater, L; Rylands, JM | 1 |
| Flavin, MT; Lu, MC; Shih, LB; Thompson, EB; Wu, L | 1 |
11 other study(ies) available for aprofen and atropine
| Article | Year |
|---|---|
Binary antidotes for organophosphate poisoning: aprophen analogues that are both antimuscarinics and carbamates.
Topics: Animals; Antidotes; Carbamates; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Organophosphate Poisoning; Parasympatholytics; Phenylpropionates; Rats; Rats, Inbred Strains | 1989 |
6-Methyl-6-azabicyclo[3.2.1]octan-3 alpha-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agent.
Topics: Acetylcholine; alpha-Amylases; Animals; Behavior, Animal; Carbachol; Cell Line; Chemical Phenomena; Chemistry; Guinea Pigs; Humans; Male; Molecular Conformation; Muscle Contraction; Neuroblastoma; Pancreas; Phenylpropionates; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Tropanes | 1987 |
Pyridophens: binary pyridostigmine-aprophen prodrugs with differential inhibition of acetylcholinesterase, butyrylcholinesterase, and muscarinic receptors.
Topics: Acetylcholinesterase; Animals; Binding, Competitive; Butyrylcholinesterase; Cerebral Cortex; Cholinesterase Inhibitors; Guinea Pigs; In Vitro Techniques; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Male; Muscarinic Antagonists; Phenylpropionates; Prodrugs; Pyridostigmine Bromide; Structure-Activity Relationship | 2002 |
3D-QSAR studies of 2,2-diphenylpropionates to aid discovery of novel potent muscarinic antagonists.
Topics: Animals; Atropine; Cell Line; Guinea Pigs; Ilium; Molecular Structure; Muscarinic Antagonists; Pancreas; Propionates; Quantitative Structure-Activity Relationship; Quantum Theory; Rats | 2009 |
Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods.
Topics: Atropine; Computer Simulation; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Receptor, Muscarinic M1; Structure-Activity Relationship | 2013 |
Relationship of the behavioral effects of aprophen, atropine and scopolamine to antagonism of the behavioral effects of physostigmine.
Topics: Animals; Atropine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Parasympatholytics; Phenylpropionates; Physostigmine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Scopolamine | 1990 |
Aprophit: an irreversible antagonist for muscarinic receptors.
Topics: Adrenal Glands; Animals; Atropine; Binding, Competitive; Brain; Catecholamines; Guinea Pigs; Male; N-Methylscopolamine; Parasympatholytics; Phenylpropionates; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thiocyanates | 1990 |
Effects of selected muscarinic cholinergic antagonists on [3H]acetylcholine release from rat hippocampal slices.
Topics: Acetylcholine; Animals; Atropine; Atropine Derivatives; Benactyzine; Carbachol; Dexetimide; Dose-Response Relationship, Drug; Electric Stimulation; Hemicholinium 3; Hippocampus; Male; Nicotine; Phenylpropionates; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Comparative effects of aprophen, atropine and benactyzine on central and peripheral cholinoceptors and on acetylcholinesterase.
Topics: Acetylcholinesterase; Animals; Atropine; Benactyzine; Brain; Guinea Pigs; In Vitro Techniques; Parasympatholytics; Phenylpropionates; Rats; Receptors, Cholinergic | 1985 |
Treatment of poisoning by soman.
Topics: Animals; Antidotes; Atropine; Carbamates; Diazepam; Guinea Pigs; Male; Motor Activity; Organophosphate Poisoning; Parasympatholytics; Phenylpropionates; Physostigmine; Pyridostigmine Bromide; Sarin; Soman; Time Factors | 1985 |
Pharmacological properties of two amino esters of diphenylpropanoic acid.
Topics: Acetylcholine; Animals; Atropine; Chemical Phenomena; Chemistry; Heart Rate; Hemodynamics; Ileum; In Vitro Techniques; Male; Methacholine Compounds; Mice; Muscle, Smooth; Parasympatholytics; Phenylpropionates; Quinuclidines; Rats; Rats, Inbred Strains; Respiration; Salivation | 1984 |