Page last updated: 2024-08-17

apomorphine and verapamil

apomorphine has been researched along with verapamil in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's3 (18.75)18.2507
2000's6 (37.50)29.6817
2010's5 (31.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bard, B; Carrupt, PA; Martel, S1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bertolucci, PH; De Andrade, LA; Ferraz, HB; Pereira, JS1
Freed, WJ; Grebb, JA; Shelton, RC1
Francès, H; Renwart, N; Simon, P1
Doğrul, A; Yeşilyurt, O1
Liang, JH; Lu, Y; Ye, XF; Zhang, P1
Balsara, JJ; Gaonkar, RK; Malekar, AR1

Reviews

1 review(s) available for apomorphine and verapamil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for apomorphine and verapamil

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A study on the action of two calcium channel blockers (verapamil and flunarizine) upon an experimental model of tardive dyskinesia in rats.
    Arquivos de neuro-psiquiatria, 1992, Volume: 50, Issue:3

    Topics: Animals; Apomorphine; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Flunarizine; Haloperidol; Male; Rats; Rats, Wistar; Stereotyped Behavior; Verapamil

1992
Diltiazem or verapamil prevents haloperidol-induced apomorphine supersensitivity in mice.
    Journal of neural transmission, 1987, Volume: 68, Issue:3-4

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Diltiazem; Drug Hypersensitivity; Haloperidol; Mice; Mice, Inbred Strains; Nifedipine; Verapamil

1987
Verapamil's lack of antidopaminergic properties in mice.
    The American journal of psychiatry, 1986, Volume: 143, Issue:7

    Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Hypothermia; Mice; Stereotyped Behavior; Verapamil

1986
Effects of Ca2+ channel blockers on apomorphine, bromocriptine and morphine-induced locomotor activity in mice.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Amlodipine; Animals; Apomorphine; Benzazepines; Bromocriptine; Calcium Channel Blockers; Diltiazem; Dopamine Antagonists; Female; Haloperidol; Heterocyclic Compounds, 4 or More Rings; Mice; Morphine; Motor Activity; Nicardipine; Time Factors; Verapamil

1999
Calmodulin inhibitor trifluoperazine attenuates the development and expression of morphine-induced conditioned place preference in rats.
    European journal of pharmacology, 2004, Feb-23, Volume: 486, Issue:3

    Topics: Animals; Apomorphine; Calcium Channel Blockers; Calmodulin; Conditioning, Psychological; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Trifluoperazine; Verapamil

2004
EFFECTS OF VERAPAMIL ON DOPAMINE DEPENDENT BEHAVIOURS IN RATS.
    Indian journal of physiology and pharmacology, 1999, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Avoidance Learning; Catalepsy; Dopamine; Haloperidol; Male; Rats; Receptors, Dopamine D2; Verapamil

1999