Page last updated: 2024-08-17

apomorphine and selegiline

apomorphine has been researched along with selegiline in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19907 (26.92)18.7374
1990's9 (34.62)18.2507
2000's7 (26.92)29.6817
2010's3 (11.54)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rinne, UK1
Levivier, M; Przedborski, S1
Quinn, N1
Bhattacharya, SK; Datla, KP1
Chambers, KC; Phoenix, CH1
Knoll, B; Knoll, J; Timar, J1
Hietala, J; Koulu, M; Scheinin, M; Syvälahti, E1
Koulu, M; Lammintausta, R2
Agnoli, A; Baldassarre, M; D'Urso, R; Del Roscio, S; Falaschi, P; Frajese, G; Mearelli, S; Rocco, A; Ruggieri, S1
Hastie, IR; Mukherjee, D1
Montastruc, JL; Rascol, O; Senard, JM1
Araya, F; Castillo, JL; Miranda, CM; Sáez, D1
Oertel, WH; Quinn, NP1
Gentsch, C; Spooren, WP; Waldmeier, P1
Chesnut, MD; Dwoskin, LP; Geddes, JW; Jakel, RJ; Maragos, WF1
Sternon, J; Supiot, F; Zegers de Beyl, D1
Chen, RC; Chen, TH; Liou, HH; Tsai, MC; Tsai, YF1
Baillet, C; Callizot, N; Guénet, JL; Poindron, P; Warter, JM1
Hayashi, K; Knoll, J; Sato, N; Shimazu, S; Tanigawa, A; Yoneda, F1
Goetz, CG; Poewe, W; Rascol, O; Sampaio, C1
Caramelli, A; Corsini, GU; Pardini, C; Vaglini, F; Viaggi, C1
de Oliveira, EF; de Rezende, IC; Fernandes, A; Ponzoni, S1

Reviews

7 review(s) available for apomorphine and selegiline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent advances in research on Parkinsonism.
    Acta neurologica Scandinavica. Supplementum, 1978, Volume: 67

    Topics: Acetylcholinesterase; Adult; Apomorphine; Benserazide; Brain; Bromocriptine; Carbidopa; Dopa Decarboxylase; Dopamine; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Levodopa; Norepinephrine; Parkinson Disease; Selegiline; Serotonin; Substance P; Tyrosine 3-Monooxygenase

1978
[Current therapeutic approach in Parkinson disease].
    Revue medicale de Bruxelles, 1992, Volume: 13, Issue:10

    Topics: Antiparkinson Agents; Apomorphine; Bromocriptine; Fetal Tissue Transplantation; Humans; Levodopa; Mesencephalon; Parkinson Disease; Selegiline; Vitamin E

1992
The modern management of Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 1990, Volume: 53, Issue:2

    Topics: Animals; Antiparkinson Agents; Apomorphine; Humans; Levodopa; Parkinson Disease; Selegiline

1990
New directions in the drug treatment of Parkinson's disease.
    Drugs & aging, 1996, Volume: 9, Issue:3

    Topics: Antiparkinson Agents; Apomorphine; Bromocriptine; Dopamine Agonists; Humans; Levodopa; Neuroprotective Agents; Parkinson Disease; Selegiline

1996
Parkinson's disease: drug therapy.
    Bailliere's clinical neurology, 1997, Volume: 6, Issue:1

    Topics: Amantadine; Antiparkinson Agents; Apomorphine; Cholinergic Antagonists; Dopamine Agonists; Dyskinesia, Drug-Induced; Guidelines as Topic; Humans; Levodopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Selegiline; Treatment Outcome

1997
Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:5

    Topics: Amantadine; Antiparkinson Agents; Apomorphine; Benzophenones; Benzothiazoles; Bromocriptine; Cabergoline; Catechol O-Methyltransferase Inhibitors; Deep Brain Stimulation; Dihydroergocryptine; Ergolines; Fetal Tissue Transplantation; Globus Pallidus; Humans; Indans; Indoles; Levodopa; Lisuride; Mesencephalon; Monoamine Oxidase Inhibitors; Neurosurgical Procedures; Nitrophenols; Parkinson Disease; Pergolide; Piribedil; Pramipexole; Selegiline; Thiazoles; Tolcapone

2005

Other Studies

19 other study(ies) available for apomorphine and selegiline

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of selective monoamine oxidase A and B inhibitors on footshock induced aggression in paired rats.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:8

    Topics: Aggression; Animals; Apomorphine; Clorgyline; Female; Male; Monoamine Oxidase; Nialamide; Pain; Rats; Rats, Inbred Strains; Selegiline

1990
Apomorphine, deprenyl, and yohimbine fail to increase sexual behavior in rhesus males.
    Behavioral neuroscience, 1989, Volume: 103, Issue:4

    Topics: Age Factors; Animals; Apomorphine; Arousal; Brain; Copulation; Dose-Response Relationship, Drug; Ejaculation; Female; Macaca mulatta; Male; Phenethylamines; Receptors, Adrenergic; Receptors, Dopamine; Selegiline; Sexual Behavior, Animal; Yohimbine

1989
Long-term administration of (-)deprenyl (selegiline), a compound which facilitates dopaminergic tone in the brain, leaves the sensitivity of dopamine receptors to apomorphine unchanged.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2

    Topics: Animals; Apomorphine; Clorgyline; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Imipramine; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Selegiline; Stereotyped Behavior

1986
Neuroendocrine aspects in monitoring of dopaminergic drugs in man.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:8

    Topics: Apomorphine; Bromocriptine; Growth Hormone; Homovanillic Acid; Humans; Levodopa; Male; Metoclopramide; Monitoring, Physiologic; Neurosecretory Systems; Prolactin; Receptors, Dopamine; Schizophrenia; Selegiline; Time Factors

1985
Human growth hormone and dopaminergic drugs, with special reference to deprenyl (selegiline): a summary of studies on volunteers.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 95

    Topics: Apomorphine; Bromocriptine; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Phenethylamines; Receptors, Dopamine; Selegiline; Synapses

1983
Presynaptic neuron and postsynaptic dopamine receptor function in long term treatment of Parkinson's disease: a neuroendocrine study.
    Progress in clinical and biological research, 1980, Volume: 39

    Topics: Aged; Apomorphine; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Levodopa; Male; Middle Aged; Nomifensine; Parkinson Disease; Prolactin; Receptors, Dopamine; Selegiline; Tremor

1980
Effects of L-deprenyl on human growth hormone secretion.
    Journal of neural transmission, 1981, Volume: 51, Issue:3-4

    Topics: Adult; Apomorphine; Growth Hormone; Humans; Kinetics; Levodopa; Male; Phenethylamines; Selegiline; Tryptophan

1981
Parkinson's disease.
    Postgraduate medical journal, 1995, Volume: 71, Issue:834

    Topics: Apomorphine; Brain; Dopamine Agonists; Humans; Levodopa; Parkinson Disease; Selegiline

1995
[Somatosensory evoked potentials and symptomatic response to dopaminergic drugs in Parkinson's disease].
    Revista medica de Chile, 1996, Volume: 124, Issue:3

    Topics: Adult; Aged; Apomorphine; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Frontal Lobe; Humans; Levodopa; Male; Median Nerve; Middle Aged; Motor Skills; Parietal Lobe; Parkinson Disease; Reaction Time; Selegiline; Walking

1996
The effect of a subchronic post-lesion treatment with (-)-deprenyl on the sensitivity of 6-OHDA-lesioned rats to apomorphine and d-amphetamine.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:9-10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Male; Medial Forebrain Bundle; Oxidopamine; Rats; Rats, Sprague-Dawley; Selegiline

1999
Does dopamine contribute to striatal damage caused by impaired mitochondrial function?
    Annals of the New York Academy of Sciences, 1999, Volume: 893

    Topics: Animals; Apomorphine; Biological Transport; Clorgyline; Corpus Striatum; Dopamine; Malonates; Medial Forebrain Bundle; Mitochondria; Monoamine Oxidase Inhibitors; Nitro Compounds; Oxidopamine; Propionates; Rats; Selegiline; Substantia Nigra

1999
[Dopaminergic agonists in the treatment of Parkinson's disease].
    Revue medicale de Bruxelles, 2000, Volume: 21, Issue:6

    Topics: Aged; Antiparkinson Agents; Apomorphine; Benzothiazoles; Biological Availability; Bromocriptine; Catechols; Dopamine Agonists; Drug Combinations; Drug Hypersensitivity; Humans; Hypotension, Orthostatic; Indoles; Levodopa; Metabolic Clearance Rate; Nitriles; Parkinson Disease; Pergolide; Pramipexole; Selegiline; Thiazoles

2000
Attenuation of paraquat-induced dopaminergic toxicity on the substantia nigra by (-)-deprenyl in vivo.
    Toxicology and applied pharmacology, 2001, Apr-01, Volume: 172, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Herbicides; Male; Neuroprotective Agents; Paraquat; Rats; Rats, Wistar; Selegiline; Stereotyped Behavior; Substantia Nigra

2001
The frissonnant mutant mouse, a model of dopamino-sensitive, inherited motor syndrome.
    Neurobiology of disease, 2001, Volume: 8, Issue:3

    Topics: Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Electromyography; Female; Genes, Recessive; Immunohistochemistry; Indoles; Levodopa; Male; Memory Disorders; Mice; Mice, Inbred C3H; Mice, Neurologic Mutants; Motor Activity; Neurons; Parkinson Disease, Secondary; Postural Balance; Selegiline; Tyrosine 3-Monooxygenase

2001
Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes.
    Life sciences, 2003, May-02, Volume: 72, Issue:24

    Topics: Animals; Apomorphine; Astrocytes; Benzofurans; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dose-Response Relationship, Drug; Glial Cell Line-Derived Neurotrophic Factor; Mice; Mice, Inbred ICR; Nerve Growth Factors; Neuroprotective Agents; Selegiline

2003
Apomorphine offers new insight into dopaminergic neuron vulnerability in mesencephalic cultures.
    Neuropharmacology, 2008, Volume: 55, Issue:5

    Topics: Animals; Apomorphine; Cell Survival; Cells, Cultured; Choline; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; L-Lactate Dehydrogenase; Mazindol; Mesencephalon; Mice; Monoamine Oxidase Inhibitors; Neurons; Pregnancy; Selegiline; Tyrosine 3-Monooxygenase

2008
Manganese neurotoxic time course is not influenced by L-deprenyl systemic treatment: influence of L-deprenyl in manganese neurotoxic time course.
    Brain research, 2010, Mar-04, Volume: 1317

    Topics: Animals; Apomorphine; Corpus Striatum; Dopamine Agonists; Immunohistochemistry; Male; Manganese; Monoamine Oxidase Inhibitors; Motor Activity; Neuroprotective Agents; Photomicrography; Rats; Rotation; Selegiline; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2010