apomorphine has been researched along with risperidone in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 13 (40.63) | 29.6817 |
| 2010's | 8 (25.00) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Awouters, FH; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| Awouters, F; Janssen, PA; Megens, AA; Niemegeers, CJ | 1 |
| Awouters, F; Janssen, PA; Meert, TF; Megens, AA; Niemegeers, CJ; Schellekens, KH | 1 |
| Janssen, PF; Leysen, JE; Megens, AA; Schotte, A | 1 |
| Awouters, FH; Janssen, PA | 1 |
| Geerts, RJ; Heykants, JJ; Leysen, JE; Megens, AA; Meuldermans, WE; van Beijsterveldt, LE; Van den Eynde, HM | 1 |
| Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT | 1 |
| Navas, F; Norman, MH; Rigdon, GC; Thompson, JB | 1 |
| Anzallo, C; Contarino, A; Drago, F; Marino, R; Raffaele, R; Rampello, L; Scapagnini, U; Valerio, C | 1 |
| Horikomi, K; Iizuka, K; Mita, N; Miwa, T; Nagase, H; Sakai, K; Sonehara, K; Takagi, K; Takahashi, S | 1 |
| Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T | 1 |
| Ago, Y; Baba, A; Matsuda, T; Sakaue, M | 1 |
| Ahnaou, A; Drinkenburg, WH; Megens, AA | 1 |
| Chopde, CT; Hirani, K; Morelli, M; Ugale, RR | 1 |
| Ago, Y; Baba, A; Hashimoto, H; Kawasaki, T; Koda, K; Matsuda, T | 1 |
| Callegaro-Filho, D; Carvalho, RC; Frussa-Filho, R; Fukushiro, DF; Helfer, DC; Sanday, L; Silva, RH; Trombin, TF; Zanlorenci, LH | 1 |
| Azar, MR; Geyer, MA; Gold, L; Marston, HM; Martin, FD; Meltzer, LT; Moore, CL; Serpa, KA; Shahid, M; Wong, EH; Young, JW | 1 |
| Mishra, A; Muthu, MS; Rawat, MK; Singh, S | 1 |
| Arakawa, R; Ikoma, Y; Ito, H; Kanno, I; Kimura, Y; Kodaka, F; Otsuka, T; Seki, C; Shidahara, M; Suhara, T; Takahashi, H; Takano, H; Turkheimer, FE | 1 |
| Bates, B; Brandon, NJ; Graf, R; Grauer, SM; Hughes, Z; Liu, F; Logue, SF; Marquis, KL; Paulsen, J; Pausch, M; Pulito, VL; Rosenzweig-Lipson, S; Sung, MA; Taylor, N; Zhang, L | 1 |
| Arakawa, R; Farde, L; Halldin, C; Ito, H; Kodaka, F; Miyoshi, M; Nakayama, K; Okumura, M; Otsuka, T; Suhara, T; Takahashi, H; Takano, H | 1 |
| Bienkowski, P; Kolaczkowski, M; Marcinkowska, M; Mierzejewski, P; Pawlowski, M; Samochowiec, J; Wesolowska, A | 1 |
| Ikeda, K; Iwamura, Y; Katsura, Y; Kobayashi, A; Matsumoto, A; Matsumoto, K; Nakako, T; Ogi, Y; Yamaguchi, M | 1 |
1 review(s) available for apomorphine and risperidone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for apomorphine and risperidone
| Article | Year |
|---|---|
Effect of risperidone on high-affinity state of dopamine D2 receptors: a PET study with agonist ligand [11C](R)-2-CH3O-N-n-propylnorapomorphine.
Topics: Adult; Apomorphine; Brain; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Ligands; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Risperidone; Schizophrenia; Young Adult | 2011 |
30 other study(ies) available for apomorphine and risperidone
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Pharmacological profile of the new potent neuroleptic ocaperidone (R 79,598).
Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Behavior, Animal; Body Temperature; Dogs; Dopamine Agents; Dopamine Antagonists; Eating; Female; Haloperidol; Isoxazoles; Lethal Dose 50; Locomotion; Male; Mice; Motor Activity; Muscles; Neurotransmitter Agents; Piperidines; Posture; Pyrimidinones; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Serotonin; Serotonin Antagonists; Synaptic Transmission | 1992 |
Functional interaction between serotonin-S2 and dopamine-D2 neurotransmission as revealed by selective antagonism of hyper-reactivity to tryptamine and apomorphine.
Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Injections, Intravenous; Isoxazoles; Male; Piperidines; Rats; Rats, Inbred Strains; Risperidone; Ritanserin; Seizures; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tryptamines | 1990 |
Pharmacology of risperidone (R 64 766), a new antipsychotic with serotonin-S2 and dopamine-D2 antagonistic properties.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Conditioning, Psychological; Dogs; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Isoxazoles; Male; Motor Activity; Oxazoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists | 1988 |
Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography.
Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Clozapine; Guinea Pigs; Haloperidol; In Vitro Techniques; Iodine Radioisotopes; Isoxazoles; Male; Mescaline; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Risperidone; Stereotyped Behavior | 1993 |
Is it possible to predict the clinical effects of neuroleptics from animal data? Part V: From haloperidol and pipamperone to risperidone.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Butyrophenones; Dogs; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; In Vitro Techniques; Isoxazoles; Lysergic Acid Diethylamide; Motor Activity; Neostriatum; Oxygen Consumption; Piperidines; Rats; Risperidone; Schizophrenia; Serotonin Antagonists; Species Specificity; Tryptamines | 1994 |
Regional brain distribution of risperidone and its active metabolite 9-hydroxy-risperidone in the rat.
Topics: Animals; Antiemetics; Antipsychotic Agents; Apomorphine; Brain; Dogs; Half-Life; Injections, Subcutaneous; Isoxazoles; Male; Neurotransmitter Uptake Inhibitors; Norepinephrine; Organ Size; Paliperidone Palmitate; Piperidines; Pyrimidines; Rats; Rats, Wistar; Receptors, Neurotransmitter; Risperidone; Spectrophotometry, Ultraviolet; Tryptamines | 1994 |
Effects of atypical antipsychotic agents on social behavior in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior | 1993 |
Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Benzamides; Clozapine; Heterocyclic Compounds; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Piperazines; Raclopride; Receptors, Dopamine; Receptors, Serotonin; Risperidone; Salicylamides; Thiazoles | 1996 |
Effects of acute or chronic administration of risperidone on motor and sexual behavior of male rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Behavior, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Rats; Risperidone; Sexual Behavior, Animal; Statistics, Nonparametric | 1997 |
Pharmacological profile of MS-377, a novel antipsychotic agent with selective affinity for sigma receptors.
Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Dopamine Agonists; Free Radical Scavengers; Guinea Pigs; Haloperidol; Head Movements; Male; Mice; Phenazocine; Phencyclidine; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, sigma; Risperidone; Serotonin; Serotonin Antagonists; Stereotyped Behavior; Sulpiride; Tartrates | 1999 |
The serotonin 5-HT(2A) receptor subtype does not mediate apomorphine-induced aggressive behaviour in male Wistar rats.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Ritanserin; Serotonin Antagonists; Time Factors | 2000 |
The 5-HT1A receptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Administration, Oral; Animals; Apomorphine; Dioxanes; Dioxoles; Dizocilpine Maleate; Drug Interactions; Male; Mice; Piperazines; Pyridines; Reflex, Startle; Risperidone; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Social Isolation | 2003 |
The atypical antipsychotics risperidone, clozapine and olanzapine differ regarding their sedative potency in rats.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Clozapine; Conscious Sedation; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Combinations; Electroencephalography; Fourier Analysis; Hypnotics and Sedatives; Male; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Risperidone; Stereotyped Behavior; Time Factors | 2003 |
Role of neuroactive steroid allopregnanolone in antipsychotic-like action of olanzapine in rodents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Behavior, Animal; Benzodiazepines; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Neurotransmitter Agents; Olanzapine; Pregnanolone; Rats; Rats, Sprague-Dawley; Risperidone; Social Isolation | 2004 |
Galantamine and donepezil differently affect isolation rearing-induced deficits of prepulse inhibition in mice.
Topics: Aconitine; Acoustic Stimulation; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Outbred Strains; Apomorphine; Behavior, Animal; Cholinesterase Inhibitors; Dizocilpine Maleate; Donepezil; Dose-Response Relationship, Drug; Galantamine; Indans; Male; Mecamylamine; Mice; Neural Inhibition; Nicotinic Antagonists; Piperidines; Receptors, Nicotinic; Reflex, Startle; Risperidone; Social Isolation | 2008 |
Long-term haloperidol treatment (but not risperidone) enhances addiction-related behaviors in mice: role of dopamine D2 receptors.
Topics: Amphetamine-Related Disorders; Animals; Antipsychotic Agents; Apomorphine; Corpus Striatum; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Female; Haloperidol; Limbic System; Long-Term Care; Mesencephalon; Mice; Motor Activity; Neural Pathways; Receptors, Dopamine D2; Risperidone; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra; Up-Regulation | 2009 |
Asenapine effects in animal models of psychosis and cognitive function.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Attention; Benzodiazepines; Cognition; Dibenzocycloheptenes; Disease Models, Animal; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Male; Olanzapine; Psychotic Disorders; Rats; Rats, Sprague-Dawley; Risperidone | 2009 |
PLGA nanoparticle formulations of risperidone: preparation and neuropharmacological evaluation.
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Drug Compounding; Lactic Acid; Mice; Microscopy, Atomic Force; Movement; Nanoparticles; Nervous System; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Risperidone; Solutions; Treatment Outcome | 2009 |
Measurement error analysis for the determination of dopamine D(2) receptor occupancy using the agonist radioligand [(11)C]MNPA.
Topics: Algorithms; Antipsychotic Agents; Apomorphine; Cerebellum; Computer Simulation; Data Interpretation, Statistical; Humans; Kinetics; Least-Squares Analysis; Male; Models, Statistical; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Dopamine D2; Risperidone; Young Adult | 2010 |
The orphan GPCR, GPR88, modulates function of the striatal dopamine system: a possible therapeutic target for psychiatric disorders?
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Mice; Mice, Knockout; Motor Activity; Neuropsychological Tests; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Reflex, Startle; Risperidone | 2009 |
Antipsychotic-like effects of zolpidem in Wistar rats.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Catalepsy; Diazepam; Dose-Response Relationship, Drug; Male; Motor Activity; Prepulse Inhibition; Pyridines; Rats; Rats, Wistar; Reflex, Startle; Risperidone; Zolpidem | 2016 |
Risperidone on apomorphine-induced stereotyped behavior and auditory sensory gating in rhesus monkeys.
Topics: Animals; Apomorphine; Macaca mulatta; Risperidone; Sensory Gating; Stereotyped Behavior | 2022 |