Page last updated: 2024-08-17

apomorphine and probenecid

apomorphine has been researched along with probenecid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Korf, J; Westerink, BH3
Hefti, F1
Carter, CJ; Pycock, CJ1
Kuschinsky, K1
Grasdijk, L; Korf, J; Westerink, BH1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
Chase, TN1
Bartholini, G; Keller, HH; Pletscher, A1
Altagracia, M; Flores, A; Kravzov, J; Rios, C; Santamaria, A1

Reviews

2 review(s) available for apomorphine and probenecid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopamine; Drug-Related Side Effects and Adverse Reactions; Extrapyramidal Tracts; Haloperidol; Humans; Methyltyrosines; Movement Disorders; Phenothiazines; Phenylacetates; Probenecid; Reserpine; Synaptic Transmission; Tetrabenazine; Tranquilizing Agents; Trihexyphenidyl

1972

Other Studies

16 other study(ies) available for apomorphine and probenecid

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of drugs on the formation of homovanillic acid in the rat retina.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Rats; Retina

1976
A simple, sensitive method for measuring 3,4-dihydroxyphenylacetic acid and homovanillic acid in rat brain tissue using high-performance liquid chromatography with electrochemical detection.
    Life sciences, 1979, Aug-27, Volume: 25, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Phenylacetates; Probenecid; Rats; Tissue Distribution

1979
Potentiation of haloperidol-induced catalepsy by dopamine agonists: possible involvement of central 5-hydroxytryptamine.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:4

    Topics: Animals; Apomorphine; Brain; Catalepsy; Dextroamphetamine; Dopamine; Drug Interactions; Haloperidol; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Serotonin

1979
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
    Brain research, 1976, Aug-27, Volume: 113, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine

1976
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
    European journal of pharmacology, 1976, Volume: 40, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra

1976
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
    Psychopharmacologia, 1975, Jun-19, Volume: 42, Issue:3

    Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome

1975
Effects of electrical stimulation of the nigrostriatal pathway of the rat on dopamine metabolism.
    Journal of neurochemistry, 1976, Volume: 26, Issue:3

    Topics: Afferent Pathways; Animals; Apomorphine; Chloral Hydrate; Corpus Striatum; Dopamine; Electric Stimulation; Homovanillic Acid; Isoquinolines; Male; Methyltyrosines; Probenecid; Rats; Substantia Nigra; Tyrosine

1976
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
Spontaneous and drug-induced changes of cerebral dopamine turnover during postnatal development of rats.
    Brain research, 1973, Dec-21, Volume: 64

    Topics: Animals; Apomorphine; Brain; Corpus Striatum; Dopamine; Feedback; Female; Haloperidol; Homovanillic Acid; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Receptors, Adrenergic

1973
Protective effect of probenecid on circling behavior of rats with unilateral quinollinic acid induced striatal lesions.
    Proceedings of the Western Pharmacology Society, 1993, Volume: 36

    Topics: Animals; Apomorphine; Corpus Striatum; Dizocilpine Maleate; Male; Probenecid; Quinolinic Acid; Rats; Rats, Wistar; Stereotyped Behavior

1993