apomorphine has been researched along with prazosin in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (41.86) | 18.7374 |
| 1990's | 12 (27.91) | 18.2507 |
| 2000's | 7 (16.28) | 29.6817 |
| 2010's | 6 (13.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ewing, FE; Furman, JS; Heym, JH; Howard, HR; Lowe, JA; Nagel, AA; Newman, ME; Schmidt, AW; Seeger, TF; Seymour, PA | 1 |
| Gołembiowska, K; Jaworska, L; Konarska, R; Przegaliński, E | 1 |
| Li, BH; Li, Q | 1 |
| Delini-Stula, A; Hunn, C | 1 |
| De Boer, T; De Vos, CJ; Tonnaer, JA; Van Delft, AM | 1 |
| Colin, JN; Lacomblez, L; Martin, P; Massol, J; Puech, AJ | 1 |
| Backus, LI; Grahame-Smith, DG; Sharp, T | 1 |
| Kamien, JB; Woolverton, WL | 1 |
| Fujiwara, M; Nishikawa, H; Taniguchi, T; Yokotani, K | 1 |
| Blaha, CD; Lane, RF; Rivet, JM | 1 |
| Hiley, CR; Nichols, AJ | 1 |
| Costall, B; Naylor, RJ; Tan, CC | 2 |
| Goiny, M; Uvnäs-Moberg, K | 1 |
| Dickinson, SL; Gadie, B; Tulloch, IF | 1 |
| Forler, C; Fozard, JR; Middlemiss, DN; Tricklebank, MD | 1 |
| Hoshino, Y; Iwai, S; Obara, H | 1 |
| Herr, DW; Tilson, HA | 1 |
| Costall, B; Eniojukan, JF; Naylor, RJ | 2 |
| Costall, B; Lim, SK; Naylor, RJ | 1 |
| de Wied, D; Nijkamp, FP; Nijssen, JG; van Ree, JM; Versluis, M | 1 |
| Costall, B; Gunning, SJ; Naylor, RJ; Simpson, KH | 1 |
| Alander, T; Andén, NE; Grabowska-Andén, M | 1 |
| Cools, AR; de Beltrán, KK; Kobayashi, M; Koshikawa, N; Miwa, Y | 1 |
| Kisara, K; Ohizumi, Y; Subarnas, A; Tadano, T | 1 |
| Ewing, FE; Furman, JS; Howard, HR; Jackson, E; Johnson, C; Lowe, JA; Maloney, PR; Morrone, J; Newman, ME; Robinson, GL; Schmidt, AW; Seeger, TF; Seymour, PA; Zorn, SH | 1 |
| Bakshi, VP; Geyer, MA | 1 |
| Rossi, NF | 1 |
| Fathollah, Y; Fazli-Tabaei, S; Semnanian, S; Yahyavi, SH; Zarrindast, MR | 1 |
| Bordeleau, M; Brooks, KM; Corbett, TJ; de Lannoy, I; Hendrix, JA; Kafka, S; Kamboj, RK; Kapples, KJ; Laws-Ricker, L; Lee, DK; Owolabi, J; Palermo, MG; Rizkalla, G; Shimshock, SJ; Shutske, GM; Tomer, JD; Vargas, HM | 1 |
| Archer, T; Fredriksson, A | 1 |
| Katsuragi, T; Kita, S; Morishita, H; Sakata, N; Shibata, K | 1 |
1 review(s) available for apomorphine and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
42 other study(ies) available for apomorphine and prazosin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming | 2015 |
1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Dopamine Antagonists; Haloperidol; Ketanserin; Locomotion; Male; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetrahydronaphthalenes | 1991 |
The role of dopamine in regulation of thyrotropin-releasing hormone in the striatum and nucleus accumbens of the rat.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Apomorphine; Benzazepines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Corpus Striatum; Dopamine; Ergolines; Male; Methyltyrosines; Norepinephrine; Nucleus Accumbens; Prazosin; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Thyrotropin-Releasing Hormone; Tyrosine 3-Monooxygenase | 1991 |
[Comparison of central stimulating effects between ephedrine and apomorphine].
Topics: Animals; Apomorphine; Blepharoptosis; Catalepsy; Ephedrine; Haloperidol; Male; Mice; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Sulpiride; Vomiting | 1991 |
Effects of single and repeated treatment with antidepressants on apomorphine-induced yawning in the rat: the implication of alpha-1 adrenergic mechanisms in the D-2 receptor function.
Topics: Adrenergic alpha-Agonists; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Drug Interactions; Hydroxamic Acids; Male; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Yawning | 1990 |
Neurochemical studies with the potential antipsychotic compound trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Benzazepines; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dibenzoxepins; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Membranes; Mianserin; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Yohimbine | 1990 |
Antidepressant profile of bupropion and three metabolites in mice.
Topics: Animals; Antidepressive Agents; Apomorphine; Body Temperature; Bupropion; Depression; Male; Mice; Motor Activity; Pimozide; Prazosin; Propiophenones; Propranolol; Reserpine; Yohimbine | 1990 |
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
A pharmacological analysis of the discriminative stimulus properties of d-amphetamine in rhesus monkeys.
Topics: Animals; Apomorphine; Benzazepines; Cocaine; Dextroamphetamine; Discrimination Learning; Macaca mulatta; Male; Phentolamine; Pimozide; Prazosin; Receptors, Dopamine | 1989 |
The bindings of 3H-prazosin and 3H-yohimbine to alpha adrenoceptors in the guinea-pig stomach.
Topics: Animals; Apomorphine; Binding, Competitive; Cell Membrane; Domperidone; Dopamine; Gastric Mucosa; Guinea Pigs; Male; Prazosin; Receptors, Adrenergic, alpha; Spiperone; Sympatholytics; Sympathomimetics; Tritium; Yohimbine | 1988 |
Selective inhibition of mesolimbic dopamine release following chronic administration of clozapine: involvement of alpha 1-noradrenergic receptors demonstrated by in vivo voltammetry.
Topics: Animals; Apomorphine; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Haloperidol; Limbic System; Male; Nucleus Accumbens; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reference Values; Septal Nuclei | 1988 |
Identification of adrenoceptors and dopamine receptors mediating vascular responses in the superior mesenteric arterial bed of the rat.
Topics: Animals; Apomorphine; Blood Pressure; Dopamine; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Dopamine; Xylazine | 1985 |
Mechanism of action of apomorphine on rat gastric secretion.
Topics: Adrenergic beta-Antagonists; Animals; Antipsychotic Agents; Apomorphine; Atenolol; Drug Interactions; Gastric Acid; Gastric Mucosa; Male; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors; Yohimbine | 1985 |
Effects of dopaminomimetics on the secretion of VIP-like immunoreactivity in conscious dogs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amphetamine; Animals; Apomorphine; Benzazepines; Dogs; Ergolines; Nitroglycerin; Pergolide; Piperidines; Prazosin; Receptors, Dopamine; Somatostatin; Vasoactive Intestinal Peptide | 1986 |
Alpha 1- and alpha 2-adrenoreceptor antagonists differentially influence locomotor and stereotyped behaviour induced by d-amphetamine and apomorphine in the rat.
Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Dextroamphetamine; Dioxanes; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1988 |
Subtypes of the 5-HT receptor mediating the behavioural responses to 5-methoxy-N,N-dimethyltryptamine in the rat.
Topics: Animals; Apomorphine; Behavior, Animal; Betaxolol; Haloperidol; Ketanserin; Male; Pindolol; Piperidines; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Spiperone | 1985 |
Relaxant effect of dopamine on isolated rabbit pulmonary artery.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Dinoprost; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Female; Male; Methysergide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Prazosin; Propranolol; Prostaglandins F; Pulmonary Artery; Quinpirole; Rabbits; Vasodilation; Yohimbine | 1986 |
Modulation of p,p'-DDT-induced tremor by catecholaminergic agents.
Topics: Animals; Apomorphine; Clonidine; DDT; Dopamine; Haloperidol; Male; Norepinephrine; Phenoxybenzamine; Prazosin; Propranolol; Rats; Rats, Inbred F344; Tremor; Yohimbine | 1987 |
Dopamine agonist action in mesolimbic, cortical and extrapyramidal areas to modify spontaneous climbing behaviour of the mouse.
Topics: Animals; Apomorphine; Cerebral Cortex; Dopamine; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Female; Haloperidol; Limbic System; Mice; Motor Activity; Prazosin; Sulpiride; Yohimbine | 1985 |
Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice.
Topics: Animals; Antipsychotic Agents; Apomorphine; Bromocriptine; Catecholamines; Dopamine; Dose-Response Relationship, Drug; Imidazolines; Male; Mice; Motor Activity; Prazosin; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes; Yohimbine | 1981 |
Opposite interactions between alpha- and beta-endorphin fragments with dopamine mediated responses on the rat rectum in vitro.
Topics: Acetylcholine; alpha-Endorphin; Animals; Apomorphine; beta-Endorphin; Dopamine; Endorphins; gamma-Endorphin; In Vitro Techniques; Male; Muscle, Smooth; Phenylephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Rectum | 1982 |
The mechanism of action of dopamine to inhibit field stimulation-induced contractions of guinea pig stomach strips.
Topics: Animals; Apomorphine; Catecholamines; Dopamine; Drug Interactions; Electric Stimulation; Guanfacine; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Parasympathetic Nervous System; Phenylacetates; Phenylephrine; Prazosin; Receptors, Dopamine; Stomach; Yohimbine | 1984 |
The mesolimbic nucleus accumbens is critically involved with the mediation of the motor inhibitory and facilitatory effects of dopamine agonists on mouse spontaneous climbing behaviour.
Topics: Animals; Apomorphine; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Motor Activity; Nucleus Accumbens; Prazosin; Septal Nuclei; Sulpiride; Tetrahydronaphthalenes | 1983 |
A central site of action for benzamide facilitation of gastric emptying.
Topics: Animals; Apomorphine; Atropine; Benzamides; Female; Gastric Emptying; Guinea Pigs; Male; Metoclopramide; Prazosin; Propranolol | 1983 |
Metoclopramide and sulpiride as selective blocking agents of pre- and postsynaptic dopamine receptors.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Atropine; Corpus Striatum; Dopamine; Dopamine Antagonists; Male; Metoclopramide; Norepinephrine; Prazosin; Rats; Receptors, Dopamine; Rotation; Sulpiride | 1980 |
Clozapine injected into the nucleus accumbens potentiates apomorphine-induced jaw movements.
Topics: Analysis of Variance; Animals; Apomorphine; Carbachol; Clozapine; Drug Interactions; Injections, Intravenous; Jaw; Male; Muscarinic Antagonists; N-Methylscopolamine; Nucleus Accumbens; Parasympatholytics; Prazosin; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Serotonin Antagonists | 1994 |
An alpha-adrenoceptor-mediated mechanism of hypoactivity induced by beta-amyrin palmitate.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Apomorphine; Clonidine; Dopamine Agents; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Motor Activity; Oleanolic Acid; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha; Triterpenes; Yohimbine | 1993 |
3-Benzisothiazolylpiperazine derivatives as potential atypical antipsychotic agents.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Brain; Catalepsy; Clozapine; Dopamine; Drug Design; Humans; Molecular Structure; Phosphatidylinositols; Piperazines; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Serotonin Antagonists; Thiazoles | 1996 |
Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alpha-1 noradrenergic antagonist.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; GABA-A Receptor Antagonists; Male; Muscarinic Antagonists; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Reflex, Startle | 1997 |
Dopaminergic control of angiotensin II-induced vasopressin secretion in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Angiotensin II; Animals; Apomorphine; Arginine Vasopressin; Benzazepines; Domperidone; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Hypothalamo-Hypophyseal System; Kinetics; Male; Models, Neurological; Organ Culture Techniques; Phenoxybenzamine; Prazosin; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Time Factors | 1998 |
Effects of adrenoceptor agents on apomorphine-induced licking behavior in rats.
Topics: Adrenergic Agents; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Male; Motor Activity; Phenylephrine; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic | 2000 |
Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.
Topics: Administration, Oral; Animals; Apomorphine; Benzyl Compounds; Dizocilpine Maleate; Dopamine D2 Receptor Antagonists; Indoles; Infusions, Parenteral; Isoxazoles; Piperidines; Prazosin; Rats; Receptors, Dopamine D4; Serine; Spiperone; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2002 |
An antihypokinesic action of alpha2-adrenoceptors upon MPTP-induced behaviour deficits in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Clonidine; Dopamine; Dopamine Agonists; Drug Interactions; Drug Therapy, Combination; Guanfacine; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred C57BL; Neostriatum; Neurons; Parkinsonian Disorders; Prazosin; Receptors, Adrenergic, alpha-2; Synaptic Transmission; Yohimbine | 2003 |
A new approach to finding specific dopamine D4 receptor agonists.
Topics: Adenosine Triphosphate; Adrenergic alpha-Antagonists; Amino Acid Sequence; Animals; Apomorphine; Blotting, Western; Bromocriptine; Cloning, Molecular; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Phenethylamines; Prazosin; Quinpirole; Receptors, Dopamine D2; Receptors, Dopamine D4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Vas Deferens | 2005 |