Page last updated: 2024-08-17

apomorphine and phencyclidine

apomorphine has been researched along with phencyclidine in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199020 (35.09)18.7374
1990's14 (24.56)18.2507
2000's18 (31.58)29.6817
2010's5 (8.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA1
Lombardo, F; Obach, RS; Waters, NJ1
Fessler, RG; Meltzer, HY; Sturgeon, RD1
Cannon-Spoor, HE; Freed, WJ1
Banks, AN; Fico, TA; Hutchings, DE1
Allikmets, LKh; Kharro, IaE; Lang, AE; Vasar, EE1
Bowen, WD; de Costa, BR; Hellewell, SB; Jacobson, AE; Rice, KC; Thurkauf, A; Walker, JM1
Bond, A; Neal, H1
Johnson, KM; Snell, LD1
French, ED1
Chang, KJ; Ferris, RM; Russell, A; Tang, FL1
Kameyama, T; Nabeshima, T; Yamaguchi, K2
Freedman, R; Hoffer, BJ; Johnson, SW1
Koek, W; Woods, JH1
Fukaya, H; Furukawa, H; Ishikawa, K; Kameyama, T; Nabeshima, T; Yamaguchi, K1
Cook, L; Steinfels, GF; Tam, SW1
Geary, R; Riffee, W; Stavchansky, S1
Amano, M; Furukawa, H; Kameyama, T; Nabeshima, T; Yamaguchi, K; Yoshida, S1
Poiletman, RM; Shah, AB; Shah, NS1
Kogan, MJ; Mulè, SJ; Verebey, K1
Garey, RE; Heath, RG; McQuitty, S; Tootle, D1
Adams, PM; Castellani, S2
Bickford, P; Hoffer, BJ; Hudson, JL; Johansson, M; Strömberg, I1
Grenhoff, J; Mathé, JM; Murase, S; Svensson, TH1
Dulawa, SC; Geyer, MA1
Bakshi, VP; Geyer, MA1
Furuya, Y; Kagaya, T; Nishizawa, Y; Ogura, H1
Curzon, P; Decker, MW1
Kinney, GG; Saywell, KL; Tricklebank, MD; Wilkinson, LO1
Ellison, GD; Geyer, MA; Martinez, ZA; Swerdlow, NR1
Geyer, MA; Gross, G; Lehmann-Masten, V; Swerdlow, NR; Teschendorf, HJ; Traut, M1
Annoh, N; Harano, M; Nakamura, K; Tanaka, M; Yamada, S1
Horikomi, K; Iizuka, K; Mita, N; Miwa, T; Nagase, H; Sakai, K; Sonehara, K; Takagi, K; Takahashi, S1
Geyer, MA; Halim, ND; Martinez, ZA; Oostwegel, JL; Swerdlow, NR1
Jones, CK; Shannon, HE1
Annoh, N; Hisatomi, S; Tanaka, M; Yamada, S; Yamauchi, K1
Ellison, GD; Geyer, MA; Martinez, ZA; Oostwegel, J; Swerdlow, NR1
Azampanah, A; Fletcher, PJ; Sills, TL1
Geyer, MA; Martinez, ZA; Pitcher, L; Platten, A; Pollack, E; Ro, H; Shoemaker, J; Swerdlow, NR1
Feldon, J; Higgins, GA; Leng, A; Ouagazzal, A1
Hoge, SG; Turgeon, SM1
Auerbach, PP; Crain, S; Goins, J; Onozuka, K; Shoemaker, JM; Swerdlow, NR1
Elmer, GI; Guard, H; Hercher, E; Sydnor, J; Vogel, MW1
Chang, DL; Feldon, J; Yee, BK1
Araki, H; Choshi, T; Gomita, Y; Hibino, S; Shibata, K; Suemaru, K; Umeda, K; Yasuda, K1
Love, PL; Shannon, HE1
Barr, AM; Geyer, MA; Markou, A; Powell, SB1
Geyer, MA; Hedlund, PB; Markou, A; Semenova, S; Sutcliffe, JG1
Caldwell, HK; Stephens, SL; Young, WS1
Chavez, C; Gogos, A; Jones, ME; van den Buuse, M1
Arrang, JM; Burban, A; Dumoulin, D; Frances, H; Le Pen, G; Rose, C; Sadakhom, C1
Gogos, A; Thwaites, SJ; van den Buuse, M1
Riedel, G; Robinson, L1
Brosda, J; Fink, H; Franke, RT; Pertz, HH; Tarland, E1
Christensen, KV; Christoffersen, CT; Clausen, D; Didriksen, M; Egebjerg, J; Fejgin, K; Kallunki, P; Larsen, PH; Lauridsen, JB; Mørk, A; Nielsen, J; Nielsen, V; Sotty, F; Werge, TM; Yavich, L1

Trials

1 trial(s) available for apomorphine and phencyclidine

ArticleYear
Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice.
    Molecular psychiatry, 2009, Volume: 14, Issue:2

    Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Apomorphine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Oxytocin; Phencyclidine; Psychoacoustics; Reflex, Startle; Sensory Gating; Sex Factors

2009

Other Studies

56 other study(ies) available for apomorphine and phencyclidine

ArticleYear
Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution

1992
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Phencyclidine-induced ipsilateral rotation in rats with unilateral 6-hydroxydopamine-induced lesions of the substantia nigra.
    Life sciences, 1979, Apr-02, Volume: 24, Issue:14

    Topics: Animals; Apomorphine; Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Hydroxydopamines; Male; Methyltyrosines; Phencyclidine; Rats; Stereotyped Behavior; Substantia Nigra; Time Factors

1979
A possible role of AA2 excitatory amino acid receptors in the expression of stimulant drug effects.
    Psychopharmacology, 1990, Volume: 101, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Amphetamine; Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glutamates; Mice; Motor Activity; Phencyclidine; Quinoxalines; Receptors, Amino Acid; Receptors, Cell Surface; Stereotyped Behavior

1990
Prenatal phencyclidine in rats: effects on apomorphine-induced climbing.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1

    Topics: Animals; Apomorphine; Drinking Behavior; Drug Interactions; Feeding Behavior; Female; Male; Motor Activity; Phencyclidine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains

1990
[Adaptive changes in sigma and phencyclidine receptors during the long-term use of haloperidol and raclopride in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 108, Issue:9

    Topics: Adaptation, Physiological; Animals; Apomorphine; Behavior, Animal; Drug Interactions; Haloperidol; Ketamine; Phenazocine; Phencyclidine; Raclopride; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Salicylamides; Time Factors; Tritium

1989
Synthesis and evaluation of optically pure [3H]-(+)-pentazocine, a highly potent and selective radioligand for sigma receptors.
    FEBS letters, 1989, Jul-17, Volume: 251, Issue:1-2

    Topics: Animals; Apomorphine; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Dopamine Agents; Guanidines; Guinea Pigs; Hydroxides; Molecular Structure; Pentazocine; Phencyclidine; Piperidines; Potassium; Potassium Compounds; Receptors, Dopamine; Receptors, Opioid; Receptors, sigma; Tritium

1989
Quantitative electrocortical changes in the rat induced by phencyclidine and other stimulants.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Dioxolanes; Electroencephalography; Isoquinolines; Isoxazoles; Male; Muscimol; Phencyclidine; Rats; Rats, Inbred Strains

1985
Antagonism of N-methyl-D-aspartate-induced transmitter release in the rat striatum by phencyclidine-like drugs and its relationship to turning behavior.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aspartic Acid; Benzomorphans; Chlorpromazine; Clozapine; Corpus Striatum; Cyclazocine; Dioxolanes; Dopamine; Haloperidol; Ketamine; Male; Mathematics; Motor Activity; N-Methylaspartate; Phencyclidine; Posture; Rats; Rats, Inbred Strains; Substantia Nigra

1985
Effects of N-allylnormetazocine (SKF 10,047), phencyclidine, and other psychomotor stimulants in the rat following 6-hydroxydopamine lesion of the ventral tegmental area.
    Neuropharmacology, 1986, Volume: 25, Issue:4

    Topics: Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine; Hydroxydopamines; Male; Motor Activity; Oxidopamine; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Scopolamine; Tegmentum Mesencephali

1986
Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain.
    Life sciences, 1986, Jun-23, Volume: 38, Issue:25

    Topics: Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain; Carbazoles; Clozapine; Guinea Pigs; Kinetics; Male; Methylphenidate; Mice; Phenazocine; Phencyclidine; Phenoxybenzamine; Propranolol; Receptors, Opioid; Receptors, sigma; Sulpiride

1986
Potentiation of phencyclidine-induced dopamine-dependent behaviors in rats after pretreatments with serotonin-depletors.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Dopamine; Drug Synergism; Fenclonine; Male; Methamphetamine; p-Chloroamphetamine; Phencyclidine; Rats; Rats, Inbred Strains; Serotonin; Stereotyped Behavior

1986
Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1986, Volume: 6, Issue:2

    Topics: Amphetamine; Animals; Apomorphine; Caudate Nucleus; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Hydroxydopamines; Infusions, Parenteral; Male; Oxidopamine; Phencyclidine; Rats; Rats, Inbred Strains; Time Factors

1986
Response repetition in pigeons: pharmacological and behavioral specificity.
    Psychopharmacology, 1986, Volume: 90, Issue:4

    Topics: Animals; Apomorphine; Chlordiazepoxide; Columbidae; Conditioning, Operant; Dextroamphetamine; Extinction, Psychological; Pentobarbital; Phencyclidine; Reinforcement Schedule; Satiation; Scopolamine

1986
Development of tolerance and supersensitivity to phencyclidine in rats after repeated administration of phencyclidine.
    European journal of pharmacology, 1987, Mar-03, Volume: 135, Issue:1

    Topics: Animals; Apomorphine; Blood Pressure; Drug Tolerance; Male; Methoxydimethyltryptamines; Pentobarbital; Phencyclidine; Rats; Rats, Inbred Strains; Sleep; Stereotyped Behavior

1987
Role of dopaminergic and serotonergic neuronal systems in the prefrontal cortex of rats in phencyclidine-induced behaviors.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:12

    Topics: Animals; Apomorphine; Caudate Nucleus; Cyclazocine; Dopamine; Frontal Lobe; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Stereotyped Behavior

1986
(+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine [(+)-3-PPP] but not (-)-3-PPP produces (+)-N-allylnormetazocine-like (SKF 10,047) discriminative stimuli.
    Life sciences, 1986, Dec-29, Volume: 39, Issue:26

    Topics: Animals; Apomorphine; Discrimination Learning; Dose-Response Relationship, Drug; Isomerism; Male; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Inbred F344

1986
Comparison between locomotor activity changes produced by phencyclidine and D-amphetamine in CD-1 male mice.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2

    Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Male; Mice; Mice, Inbred Strains; Motor Activity; Phencyclidine; Receptors, Dopamine

1985
Phencyclidine-induced dopamine-dependent behaviors in chronic haloperidol-treated rats.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:5

    Topics: Animals; Apomorphine; Behavior, Animal; Biogenic Amines; Brain Chemistry; Dopamine; Haloperidol; Male; Methamphetamine; Phencyclidine; Rats; Rats, Inbred F344; Stereotyped Behavior

1985
The influence of nisoldipine--a "calcium entry blocker" on drug induced stereotyped behavior in rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1983, Volume: 7, Issue:2-3

    Topics: Age Factors; Animals; Apomorphine; Arousal; Calcium Channel Blockers; Humans; Motor Activity; Nifedipine; Nisoldipine; Phencyclidine; Pyridines; Rats; Rats, Inbred Strains; Stereotyped Behavior

1983
Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone.
    Psychopharmacology, 1981, Volume: 75, Issue:1

    Topics: Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Humans; Male; Methadone; Motor Activity; Naloxone; Phencyclidine; Psychoses, Substance-Induced; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors

1981
The effects of apomorphine and haldol on PCP induced behavioral and motor abnormalities in the rat.
    Life sciences, 1980, Jan-28, Volume: 26, Issue:4

    Topics: Animals; Apomorphine; Behavior, Animal; Haloperidol; Humans; Male; Motor Activity; Phencyclidine; Psychoses, Substance-Induced; Rats; Receptors, Dopamine

1980
Effects of dopaminergic drugs on phencyclidine-induced behavior in the rat.
    Neuropharmacology, 1981, Volume: 20, Issue:4

    Topics: Analysis of Variance; Animals; Apomorphine; Ataxia; Behavior, Animal; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Motor Activity; Phencyclidine; Rats; Receptors, Dopamine; Stereotyped Behavior

1981
Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats.
    European journal of pharmacology, 1981, Jul-17, Volume: 73, Issue:2-3

    Topics: Amphetamine; Analysis of Variance; Animals; Apomorphine; Ataxia; Dose-Response Relationship, Drug; Humans; Male; Motor Activity; Phencyclidine; Rats; Stereotyped Behavior

1981
Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Brain; Corpus Striatum; Dopamine beta-Hydroxylase; Electrophysiology; Female; Fetal Tissue Transplantation; Immunohistochemistry; Neurons; Neurotransmitter Agents; Phencyclidine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1994
Effects of dizocilpine (MK-801) on rat midbrain dopamine cell activity: differential actions on firing pattern related to anatomical localization.
    Journal of neural transmission. General section, 1993, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Apomorphine; Dizocilpine Maleate; Dopamine; Male; Neurons; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Substantia Nigra; Tegmentum Mesencephali

1993
Psychopharmacology of prepulse inhibition in mice.
    The Chinese journal of physiology, 1996, Volume: 39, Issue:3

    Topics: Analysis of Variance; Animals; Apomorphine; Dextroamphetamine; Male; Mice; Mice, Inbred C57BL; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Reflex, Startle

1996
Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alpha-1 noradrenergic antagonist.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; GABA-A Receptor Antagonists; Male; Muscarinic Antagonists; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Reflex, Startle

1997
Differential effects of the strychnine-insensitive glycine site antagonist (+)-HA-966 on the hyperactivity and the disruption of prepulse inhibition induced by phencyclidine in rats.
    Brain research, 1998, Jan-19, Volume: 781, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine Agonists; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Haloperidol; Hyperkinesis; Male; Motor Activity; Phencyclidine; Pyrrolidinones; Rats; Rats, Wistar; Reflex, Startle; Strychnine

1998
Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:1

    Topics: Acoustic Stimulation; Animals; Apomorphine; Clozapine; Dextroamphetamine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Mice; Mice, Inbred Strains; Phencyclidine; Piperidines; Rats; Receptors, sigma; Reflex, Startle; Species Specificity

1998
Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-01, Volume: 19, Issue:13

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dopamine; Dopamine Agonists; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Species Specificity; Time Factors

1999
Effects of sustained phencyclidine exposure on sensorimotor gating of startle in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1

    Topics: Animals; Apomorphine; Dopamine Agonists; Drug Implants; Excitatory Amino Acid Antagonists; Female; Habituation, Psychophysiologic; Hallucinogens; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Time Factors

1999
Effects of LU-111995 in three models of disrupted prepulse inhibition in rats.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Fumarates; Hallucinogens; Male; Phencyclidine; Quinazolines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Social Isolation

1999
Involvement of serotonin 2A receptors in phencyclidine-induced disruption of prepulse inhibition of the acoustic startle in rats.
    Biological psychiatry, 1999, Sep-15, Volume: 46, Issue:6

    Topics: Animals; Antipsychotic Agents; Apomorphine; Auditory Perception; Brain; Dopamine Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Male; Neural Inhibition; Phencyclidine; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle

1999
Pharmacological profile of MS-377, a novel antipsychotic agent with selective affinity for sigma receptors.
    Psychopharmacology, 1999, Volume: 145, Issue:3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Dopamine Agonists; Free Radical Scavengers; Guinea Pigs; Haloperidol; Head Movements; Male; Mice; Phenazocine; Phencyclidine; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, sigma; Risperidone; Serotonin; Serotonin Antagonists; Stereotyped Behavior; Sulpiride; Tartrates

1999
Ontogeny of phencyclidine and apomorphine-induced startle gating deficits in rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:3

    Topics: Age Factors; Animals; Apomorphine; Dose-Response Relationship, Drug; Female; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia

2000
Effects of scopolamine in comparison with apomorphine and phencyclidine on prepulse inhibition in rats.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Acoustic Stimulation; Animals; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Muscarinic Antagonists; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Scopolamine

2000
Effects of sigma(1) receptor ligand, MS-377 on apomorphine- or phencyclidine-induced disruption of prepulse inhibition of acoustic startle in rats.
    European journal of pharmacology, 2000, Aug-25, Volume: 402, Issue:3

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Antipsychotic Agents; Apomorphine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Phencyclidine; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, sigma; Reflex, Startle; Sigma-1 Receptor; Tartrates

2000
"Early" and "late" effects of sustained haloperidol on apomorphine- and phencyclidine-induced sensorimotor gating deficits.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:5

    Topics: Animals; Antipsychotic Agents; Apomorphine; Dopamine Agonists; Drug Implants; Excitatory Amino Acid Antagonists; Haloperidol; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Reflex, Startle

2000
The adenosine A2A agonist CGS 21680 reverses the reduction in prepulse inhibition of the acoustic startle response induced by phencyclidine, but not by apomorphine and amphetamine.
    Psychopharmacology, 2001, Volume: 156, Issue:2-3

    Topics: Acoustic Stimulation; Adenosine; Amphetamine; Animals; Apomorphine; Dopamine Agonists; Dopamine Uptake Inhibitors; Hallucinogens; Injections, Intraperitoneal; Male; Motor Activity; Phencyclidine; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Reflex, Startle

2001
"Typical" but not "atypical" antipsychotic effects on startle gating deficits in prepubertal rats.
    Psychopharmacology, 2002, Volume: 161, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Dibenzothiazepines; Female; Phencyclidine; Quetiapine Fumarate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Sexual Maturation

2002
Effect of the 5-HT6 receptor antagonists Ro04-6790 and Ro65-7199 on latent inhibition and prepulse inhibition in the rat: comparison to clozapine.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:2

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Cerebral Cortex; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hippocampus; Lysergic Acid Diethylamide; Male; Maze Learning; Memory; Phencyclidine; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Serotonin Antagonists

2003
Prior exposure to phencyclidine decreases voluntary sucrose consumption and operant performance for food reward.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 76, Issue:3-4

    Topics: Animals; Apomorphine; Conditioning, Operant; Dopamine Agonists; Food; Hallucinogens; Lithium Chloride; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Reward; Sucrose; Water Deprivation

2003
Sensitivity to drug effects on prepulse inhibition in inbred and outbred rat strains.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2

    Topics: Acoustic Stimulation; Aging; Animals; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Male; Phencyclidine; Rats; Rats, Inbred ACI; Rats, Inbred BUF; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Species Specificity

2004
Altered prepulse inhibition in rats treated prenatally with the antimitotic Ara-C: an animal model for sensorimotor gating deficits in schizophrenia.
    Psychopharmacology, 2004, Volume: 174, Issue:2

    Topics: Animals; Antineoplastic Agents; Apomorphine; Brain; Cytarabine; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Female; Hallucinogens; Male; Maternal-Fetal Exchange; Phencyclidine; Pregnancy; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia

2004
The Effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:10

    Topics: Acoustic Stimulation; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Habituation, Psychophysiologic; Male; Mice; Mice, Inbred C57BL; Phencyclidine; Reflex, Startle

2004
Nicotine blocks apomorphine-induced disruption of prepulse inhibition of the acoustic startle in rats: possible involvement of central nicotinic alpha7 receptors.
    British journal of pharmacology, 2004, Volume: 142, Issue:5

    Topics: Acoustic Stimulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apomorphine; Central Nervous System; Clozapine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Haloperidol; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phencyclidine; Rats; Rats, Wistar; Receptors, Nicotinic; Reflex, Startle

2004
Within-session repeated acquisition behavior in rats as a potential model of executive function.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Animals; Apomorphine; Behavior, Animal; Cognition; Conditioning, Operant; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Models, Animal; Motor Activity; Muscarinic Antagonists; Phencyclidine; Psychomotor Performance; Rats; Rats, Inbred F344; Scopolamine; Triazolam

2004
Iloperidone reduces sensorimotor gating deficits in pharmacological models, but not a developmental model, of disrupted prepulse inhibition in rats.
    Neuropharmacology, 2006, Volume: 51, Issue:3

    Topics: Acoustic Stimulation; Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Gait Disorders, Neurologic; Imidazoles; Isoxazoles; Male; Neural Inhibition; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Reflex, Startle

2006
Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition.
    Biological psychiatry, 2008, Jan-01, Volume: 63, Issue:1

    Topics: Acoustic Stimulation; Amphetamine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Phencyclidine; Phenols; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Serotonin Antagonists; Sulfonamides

2008
Psychotropic drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (ArKO) mice: role of dopamine D1 and D2 receptors and dopamine transporters.
    Psychopharmacology, 2009, Volume: 206, Issue:2

    Topics: Acoustic Stimulation; Animals; Apomorphine; Aromatase; Autoradiography; Behavior, Animal; Caudate Nucleus; Cross-Over Studies; Dizocilpine Maleate; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Excitatory Amino Acid Antagonists; Humans; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neural Inhibition; Nucleus Accumbens; Phencyclidine; Protein Binding; Psychoacoustics; Psychotropic Drugs; Random Allocation; Receptors, Dopamine D1; Receptors, Dopamine D2; Reflex, Startle; Sex Factors; Time Factors

2009
Modulation of prepulse inhibition and stereotypies in rodents: no evidence for antipsychotic-like properties of histamine H3-receptor inverse agonists.
    Psychopharmacology, 2010, Volume: 210, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzofurans; Dizocilpine Maleate; Drug Inverse Agonism; Haloperidol; Histamine Antagonists; Imidazoles; Inhibition, Psychological; Male; Methamphetamine; Mice; Phencyclidine; Piperidines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Stereotyped Behavior

2010
Differential effects of estrogen and testosterone on auditory sensory gating in rats.
    Psychopharmacology, 2014, Volume: 231, Issue:1

    Topics: Amphetamine; Animals; Apomorphine; Auditory Perception; Body Weight; Central Nervous System Stimulants; Dopamine Agonists; Electrodes, Implanted; Electroencephalography; Electromyography; Estrogens; Evoked Potentials, Auditory; Female; Male; Orchiectomy; Organ Size; Ovariectomy; Phencyclidine; Rats; Rats, Sprague-Dawley; Sensory Gating; Sex Characteristics; Testosterone; Uterus

2014
Comparison of automated home-cage monitoring systems: emphasis on feeding behaviour, activity and spatial learning following pharmacological interventions.
    Journal of neuroscience methods, 2014, Aug-30, Volume: 234

    Topics: Animals; Apomorphine; Cholinergic Antagonists; Dopamine Agonists; Dose-Response Relationship, Drug; Electronic Data Processing; Excitatory Amino Acid Antagonists; Exploratory Behavior; Feeding Behavior; Female; History, 20th Century; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Monitoring, Physiologic; Motor Activity; Phencyclidine; Piperidines; Pyrazoles; Scopolamine; Spatial Learning

2014
Effects of 2-bromoterguride, a dopamine D
    Psychopharmacology, 2018, Volume: 235, Issue:1

    Topics: Animals; Antipsychotic Agents; Apomorphine; Cognition Disorders; Dopamine Agonists; Lisuride; Male; Memory Disorders; Phencyclidine; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Recognition, Psychology; Reflex, Startle; Schizophrenic Psychology; Social Behavior

2018
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
    Translational psychiatry, 2017, 11-30, Volume: 7, Issue:11

    Topics: Abnormalities, Multiple; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Chromosome Deletion; Chromosomes, Human, Pair 1; Disease Models, Animal; Dopamine Agonists; Dopamine Uptake Inhibitors; Dopaminergic Neurons; Excitatory Amino Acid Antagonists; Megalencephaly; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Phencyclidine; Phenotype; Prepulse Inhibition; Quinpirole; Receptors, Dopamine; Schizophrenia; Ventral Tegmental Area

2017