Page last updated: 2024-08-17

apomorphine and papaverine

apomorphine has been researched along with papaverine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (43.33)	18.7374
1990's	3 (10.00)	18.2507
2000's	10 (33.33)	29.6817
2010's	4 (13.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carchedi, F; Casacchia, M; Cerbo, R; Meco, G	1
Bidzinski, A; Gajewska, S; Hauptman, M; Kostowski, W	1
Ackerman, M; Artman, LD; Asin, KE; Bednarz, L; Johnson, MC; Kebabian, JW; Kerkman, DJ; MacKenzie, RG; Montana, W; Stampfli, H	1
Alexandre, L; Benoit, G; Bensadoun, H; Jardin, A; Puech, A	1
Binns, J; Nahorski, SR; Rogers, KJ	1
Sheppard, H; Wiggan, G	1
Brittain, RT; Kruk, ZL	1
Bass, P; Kennedy, JA; Wiley, JN	1
Kühn, L; Pfeifer, S	1
Paris, R; Sarsúnová, M	1
Rosazza, JP; Smith, RV	1
Cubeddu, LX; Hoffman, IS	1
Baba, K; Carrier, S; Lue, TF; Morgan, DM; Nagaraju, P; Nunes, L	1
Anselmi, E; Catret, M; D'Ocón, MP; Ivorra, MD	1
Moncada Iribarren, I; Sáenz de Tejada, I	1
Akkus, E; Baba, K; Carrier, S; Iwamoto, T; Lue, TF; Nunes, L; Reman, J; Yajima, M	1
Castaneda, J; Castell, R; Hurley, D; Lammers, PI; Lipezker, M; Loehr, LA; Lowrey, F; Ponce de Leon, R; Rubio-Aurioles, E	1
Thomas, JA	1
Cestari, A; Deho', F; Guazzoni, G; Montorsi, F; Rigatti, P; Salonia, A; Stief, C	1
Erdei, E; Papp, G	1
SCHIESER, DW	1
Han, YF; Huang, XY; Leng, J; Li, Z; Wang, YX; Xiang, ZQ; Zhang, XS	1
Hatzichristou, DG; Hatzimouratidis, K	1
Breier, M; Ko, D; Marzan, DE; Swerdlow, NR; Thangaraj, N; Weber, M	1

Reviews

7 review(s) available for apomorphine and papaverine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Theories and findings on the biosynthesis of aporphine and morphine alkaloids with special reference to dienone structures]. Die Pharmazie, 1965, Volume: 20, Issue:11 Topics: Apomorphine; Morphine; Papaverine	1965
Pharmacological treatment of erectile dysfunction. Current opinion in urology, 1999, Volume: 9, Issue:6 Topics: Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Male; Muscle Relaxation; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents	1999
Pharmacological aspects of erectile dysfunction. Japanese journal of pharmacology, 2002, Volume: 89, Issue:2 Topics: Adult; Aged; Alprostadil; Apomorphine; Drug Interactions; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Phentolamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Testosterone; Trazodone	2002
Pharmacological management of erectile dysfunction. BJU international, 2003, Volume: 91, Issue:5 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Carbolines; Drug Combinations; Erectile Dysfunction; Humans; Imidazoles; Injections; Male; Papaverine; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones; Tadalafil; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents	2003
[Conservative treatment of erectile dysfunction]. Orvosi hetilap, 2003, Jun-01, Volume: 144, Issue:22 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Alprostadil; Apomorphine; Dopamine Agonists; Erectile Dysfunction; Humans; Imidazoles; Impotence, Vasculogenic; Injections; Male; Nitric Oxide; Papaverine; Phosphodiesterase Inhibitors; Piperazines; Psychotherapy; Purines; Sildenafil Citrate; Sulfones; Triazines; Vacuum; Vardenafil Dihydrochloride; Vasodilator Agents	2003
A comparative review of the options for treatment of erectile dysfunction: which treatment for which patient? Drugs, 2005, Volume: 65, Issue:12 Topics: Administration, Oral; Alprostadil; Apomorphine; Carbolines; Constriction; Contraindications; Dopamine Agonists; Drug Combinations; Enzyme Inhibitors; Erectile Dysfunction; Humans; Imidazoles; Male; Papaverine; Patient Satisfaction; Penile Prosthesis; Penis; Phentolamine; Phosphodiesterase Inhibitors; Piperazines; Purines; Regional Blood Flow; Sildenafil Citrate; Sulfones; Tadalafil; Treatment Failure; Triazines; Vardenafil Dihydrochloride; Vasodilator Agents	2005

Trials

1 trial(s) available for apomorphine and papaverine

Article	Year
Combination therapy for erectile dysfunction: a randomized, double blind, unblinded active-controlled, cross-over study of the pharmacodynamics and safety of combined oral formulations of apomorphine hydrochloride, phentolamine mesylate and papaverine hyd International journal of impotence research, 2002, Volume: 14, Issue:1 Topics: Adrenergic alpha-Antagonists; Apomorphine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Erectile Dysfunction; Humans; Male; Papaverine; Phentolamine; Piperazines; Purines; Safety; Severity of Illness Index; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents	2002

Article

Year

Combination therapy for erectile dysfunction: a randomized, double blind, unblinded active-controlled, cross-over study of the pharmacodynamics and safety of combined oral formulations of apomorphine hydrochloride, phentolamine mesylate and papaverine hyd

International journal of impotence research, 2002, Volume: 14, Issue:1

Topics: Adrenergic alpha-Antagonists; Apomorphine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Erectile Dysfunction; Humans; Male; Papaverine; Phentolamine; Piperazines; Purines; Safety; Severity of Illness Index; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents

2002

Other Studies

22 other study(ies) available for apomorphine and papaverine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Effect of phosphodiesterase inhibitors on neuroleptic-induced catalepsy and apomorphine-induced stereotypic movements in rats]. Bollettino della Societa italiana di biologia sperimentale, 1978, Apr-30, Volume: 54, Issue:8 Topics: Animals; Apomorphine; Atropine; Catalepsy; Haloperidol; Humans; Movement Disorders; Papaverine; Phosphodiesterase Inhibitors; Rats	1978
Papaverine, drug-induced stereotypy and catalepsy and biogenic amines in the brain of the rat. Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:1 Topics: Animals; Apomorphine; Behavior; Biogenic Amines; Brain; Brain Chemistry; Catalepsy; Dopamine; Haloperidol; Humans; Hydroxyindoleacetic Acid; Male; Norepinephrine; Papaverine; Rats; Serotonin; Stereotyped Behavior	1976
A-69024: a non-benzazepine antagonist with selectivity for the dopamine D-1 receptor. European journal of pharmacology, 1989, Aug-03, Volume: 166, Issue:3 Topics: Adenylyl Cyclases; Animals; Apomorphine; Benzazepines; Binding, Competitive; Catalepsy; Dihydroxyphenylalanine; Haloperidol; Injections, Subcutaneous; Iodine Radioisotopes; Male; Motor Activity; Papaverine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Tetrahydroisoquinolines	1989
[What can be expected of intracavernous injections?]. Acta urologica Belgica, 1988, Volume: 56, Issue:2 Topics: Adult; Aged; Apomorphine; Erectile Dysfunction; Humans; Injections; Injections, Subcutaneous; Male; Middle Aged; Moxisylyte; Papaverine; Penis; Vasodilator Agents	1988
Letter: Cerebral phosphodiesterase and the dopamine receptor. The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:11 Topics: Adenosine Monophosphate; Animals; Apomorphine; Brain; Dopamine; Papaverine; Phenethylamines; Phosphoric Diester Hydrolases; Rats; Receptors, Drug; Tritium; Tyramine	1973
Different sensitivities of the phosphodiesterases (adenosine-3',5'-cyclic phosphate 3'-phosphohydrolase) of dog cerebral cortex and erythrocytes to inhibition by synthetic agents and cold. Biochemical pharmacology, 1971, Volume: 20, Issue:8 Topics: Animals; Apomorphine; Benzyl Compounds; Cerebral Cortex; Cold Temperature; Cyclic AMP; Dogs; Erythrocytes; Imidazoles; In Vitro Techniques; Ketones; Papaverine; Phenylacetates; Phosphoric Monoester Hydrolases; Rats; Temperature; Theophylline	1971
Changes in body core and skin temperature following intracerebroventricular injection of substances in the conscious rat: interpretation of data. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:10 Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Body Temperature; Cerebral Ventricles; Dopamine; Epinephrine; Ergotamine; Injections; Male; Norepinephrine; Oxymetazoline; Papaverine; Rats; Skin Temperature; Vasopressins	1972
Measurement of fecal output in rats. The American journal of digestive diseases, 1972, Volume: 17, Issue:10 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats	1972
[Thin layer chromatographic separation of opium alkaloids and various products of partial synthetic modification]. Die Pharmazie, 1967, Volume: 22, Issue:9 Topics: Apomorphine; Chromatography, Thin Layer; Codeine; Methods; Morphine; Noscapine; Opium; Papaverine; Thebaine	1967
Microbial models of mammalian metabolism. Journal of natural products, 1983, Volume: 46, Issue:1 Topics: Acronine; Animals; Apomorphine; Biotransformation; Dealkylation; Ellipticines; Ergolines; Guinea Pigs; Humans; Hydroxylation; Imipramine; Mammals; Models, Biological; Papaverine; Pharmaceutical Preparations	1983
Presynaptic effects of tetrahydropapaveroline on striatal dopaminergic neurons. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:1 Topics: Animals; Apomorphine; Benztropine; Bromocriptine; Caudate Nucleus; Dopamine; Female; Haloperidol; In Vitro Techniques; Male; Neurons; Papaverine; Putamen; Rabbits; Synapses; Tetrahydropapaveroline	1982
Age decreases nitric oxide synthase-containing nerve fibers in the rat penis. The Journal of urology, 1997, Volume: 157, Issue:3 Topics: Aging; Animals; Apomorphine; Dopamine Agonists; Electric Stimulation; Male; Nerve Fibers; Nitric Oxide Synthase; Papaverine; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Vasoactive Intestinal Peptide; Vasodilator Agents	1997
The 5-HT and alpha-adrenoceptor antagonist effect of four benzylisoquinoline alkaloids on rat aorta. The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:3 Topics: Adrenergic alpha-Antagonists; Alkaloids; Animals; Aorta, Thoracic; Apomorphine; Aporphines; Benzylisoquinolines; Calcium Channel Blockers; Dopamine Agonists; Dose-Response Relationship, Drug; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Papaverine; Parasympatholytics; Rats; Rats, Wistar; Serotonin	1998
Effect of testosterone on the number of NADPH diaphorase-stained nerve fibers in the rat corpus cavernosum and dorsal nerve. Urology, 2000, Sep-01, Volume: 56, Issue:3 Topics: Animals; Apomorphine; Dopamine Agonists; Electric Stimulation; Male; NADP; Orchiectomy; Papaverine; Penile Erection; Penis; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Testosterone	2000
FREE RADICALS IN ALKALOIDAL COLOR IDENTIFICATION TESTS. Journal of pharmaceutical sciences, 1964, Volume: 53 Topics: Apomorphine; Benzene; Chemistry, Pharmaceutical; Codeine; Free Radicals; Meperidine; Morphine; Papaverine; Pharmacy; Phenols; Research; Salicylic Acid; Spectrophotometry	1964
[Effects of growth hormone supplementation on erectile function and expression of nNOS in aging rats]. Zhonghua nan ke xue = National journal of andrology, 2005, Volume: 11, Issue:5 Topics: Animals; Apomorphine; Growth Hormone; Immunohistochemistry; Male; Nitric Oxide Synthase Type I; Papaverine; Penile Erection; Penis; Random Allocation; Rats; Rats, Sprague-Dawley	2005
Evaluating the antipsychotic profile of the preferential PDE10A inhibitor, papaverine. Psychopharmacology, 2009, Volume: 203, Issue:4 Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Biological Availability; Body Temperature; Dopamine Agonists; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reflex, Startle	2009