Page last updated: 2024-08-17

apomorphine and naltrexone

apomorphine has been researched along with naltrexone in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (50.00)	18.7374
1990's	8 (21.05)	18.2507
2000's	8 (21.05)	29.6817
2010's	3 (7.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Biggio, G; Costa, E; Guidotti, A	1
Amir, S; Amit, Z; Blair, R	1
Appel, JB; Hernandez, LL; Holohean, AM	1
Cheney, DL; Costa, E; Moroni, F; Peralta, E	1
Eades, CG; Gilbert, PE; Huppler, RE; Martin, WR; Thompson, JA	1
Kameyama, T; Toyoshi, T; Ukai, M	3
Baraban, JM; Bhat, RV; Cole, AJ; Worley, PF	1
Ceresoli, G; Groppetti, A; Mandelli, V; Parenti, M	1
Kameyama, T; Nakayama, S; Ukai, M	2
Cabib, S; Oliverio, A; Puglisi-Allegra, S	2
Childress, AR; McLellan, AT	1
Lauber, AH; Whalen, RE	1
Fries, DS; Kouchich, FJ; Quock, RM	1
Clemens, JA; Shaar, CJ	1
Fratta, W; Grandison, L; Guidotti, A	1
Holtzman, SG; Teal, JJ	1
Iwamoto, ET	1
Shuster, L; Thompson, ML; Weiss, J	1
Schechter, MD	1
Lucas, TS; Quock, RM	1
Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T	1
Flumerfelt, BA; Newman, DD; Rajakumar, N; Stoessl, AJ	1
Foss, JF; Goldberg, LI; Roizen, MF; Yuan, CS	1
Aston-Jones, G; Druhan, JP; Walters, CL	2
Okuda, A; Ukai, M	1
Aru, GN; Bortolato, M; Fà, M; Frau, R; Gessa, GL; Manunta, M; Mereu, G; Orrù, M; Puddu, M	1
Adaikan, G; Becher, E; Brock, G; Carrier, S; Carson, C; Christ, G; Corbin, J; DeBusk, R; Eardley, I; Francis, S; Hedlund, H; Hutter, A; Jackson, G; Kloner, R; Lin, CS; Lin, S; McCullough, A; McVary, K; Nehra, A; Padma-Nathan, H; Porst, H; Schulman, C; Seftel, A; Sharlip, I; Stief, C; Teloken, C	1

Reviews

3 review(s) available for apomorphine and naltrexone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Aversive therapies for substance abuse: do they work? Journal of substance abuse treatment, 1985, Volume: 2, Issue:3 Topics: Apomorphine; Aversive Therapy; Conditioning, Classical; Desensitization, Psychologic; Electroshock; Emetine; Extinction, Psychological; Humans; Naltrexone; Patient Compliance; Research Design; Substance Withdrawal Syndrome; Substance-Related Disorders; Succinylcholine	1985
Progesterone substitutes: cGMP mediation. Neuroscience and biobehavioral reviews, 1986,Spring, Volume: 10, Issue:1 Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Apomorphine; Brain; Brain Mapping; Cyclic GMP; Estradiol; Estrus; Female; Gonadotropin-Releasing Hormone; Guanosine Triphosphate; Hypothalamus; Lysergic Acid Diethylamide; Naltrexone; Neurotransmitter Agents; Ovariectomy; Posture; Progesterone; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Synaptic Transmission	1986

Other Studies

35 other study(ies) available for apomorphine and naltrexone

Article	Year
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
On the mechanism of the decrease in cerebellar cyclic GMP content elicited by opiate receptor agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 296, Issue:2 Topics: Analgesics; Animals; Apomorphine; Cerebellum; Corpus Striatum; Cyclic GMP; Dextromoramide; Ethanolamines; Injections; Male; Morphine; Naltrexone; Narcotics; Pyridines; Rats; Reaction Time; Receptors, Opioid; Time Factors	1977
Increased amphetamine potency following chronic naltrexone administration in rats. Life sciences, 1979, Oct-15, Volume: 25, Issue:16 Topics: Animals; Apomorphine; Dextroamphetamine; Drug Synergism; Male; Motor Activity; Naloxone; Naltrexone; Rats; Time Factors	1979
Effects of opiates on the discriminative stimulus properties of dopamine agonists. Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:4 Topics: Amphetamine; Animals; Apomorphine; Discrimination, Psychological; Dopamine; Haloperidol; Male; Morphine; Naltrexone; Narcotics; Pentazocine; Rats; Time Factors	1978
On the regulation of gamma-aminobutyric acid neurons in caudatus, pallidus and nigra: effects of opioids and dopamine agonists. The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:2 Topics: Animals; Apomorphine; Brain; Caudate Nucleus; Corpus Striatum; Decerebrate State; Dopamine; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Male; Morphine; Naltrexone; Narcotics; Neurons; Rats; Substantia Nigra	1979
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3 Topics: Animals; Apomorphine; Cyclazocine; Cyclopropanes; Dextropropoxyphene; Dogs; Ethylketocyclazocine; Humans; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naltrexone; Phenazocine; Spinal Cord	1976
Effects of [D-Ala2, D-Leu5]enkephalin and [D-Pen2, L-Pen5]enkephalin on apomorphine-induced motor activity in the mouse. Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1 Topics: Analgesics; Animals; Apomorphine; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Grooming; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Motor Activity; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereotyped Behavior	1992
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268. Brain research. Molecular brain research, 1992, Volume: 13, Issue:3 Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Electroshock; Haloperidol; Immediate-Early Proteins; Male; Morphine; Naltrexone; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Substance Withdrawal Syndrome; Transcription Factors; Transcription, Genetic; Zinc Fingers	1992
DAGO ([D-Ala2,N-Me-Phe4,Gly-ol]enkephalin) specifically reverses apomorphine-induced increase in rearing and grooming behaviors in the mouse. Brain research, 1991, Aug-23, Volume: 557, Issue:1-2 Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Grooming; Injections, Intraventricular; Mice; Mice, Inbred Strains; Motor Activity; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, mu	1991
Role of opiates in striatal D-1 dopamine receptor supersensitivity induced by chronic L-dopa treatment. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3 Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Drug Interactions; Hydroxydopamines; Levodopa; Male; Morphine; Naltrexone; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Opioid	1990
Inhibition of drinking by naltrexone in the rat: interaction with the dopamine D-1 antagonist SCH 23390 and the D-2 antagonist sulpiride. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:3 Topics: Animals; Apomorphine; Benzazepines; Dose-Response Relationship, Drug; Drinking Behavior; Male; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride	1989
Stress-induced decrease of 3-methoxytyramine in the nucleus accumbens of the mouse is prevented by naltrexone pretreatment. Life sciences, 1989, Volume: 45, Issue:12 Topics: Animals; Apomorphine; Behavior, Animal; Dopamine; Male; Mice; Mice, Inbred DBA; Naltrexone; Nucleus Accumbens; Septal Nuclei; Stress, Physiological	1989
Apomorphine markedly potentiates naltrexone-induced hypodipsia in the rat. Brain research, 1988, Jun-07, Volume: 451, Issue:1-2 Topics: Animals; Apomorphine; Drinking; Male; Naltrexone; Rats; Rats, Inbred Strains	1988
Narcotic antagonist potentiation of apomorphine drug effect: a stereospecific, centrally mediated drug action. Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:3 Topics: Animals; Apomorphine; Drug Synergism; Exploratory Behavior; Humans; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Stereoisomerism; Stereotyped Behavior	1985
The effects of opiate agonists on growth hormone and prolactin release in rats. Federation proceedings, 1980, Volume: 39, Issue:8 Topics: Animals; Apomorphine; Enkephalins; Growth Hormone; Male; Methadone; Morphine; Naloxone; Naltrexone; Parasympathomimetics; Prolactin; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Opioid; Secretory Rate	1980
Location and characterization of opiate receptors regulating pituitary secretion. Life sciences, 1980, May-12, Volume: 26, Issue:19 Topics: Animals; Apomorphine; Chromatography, Gel; Corpus Striatum; Endorphins; Enkephalins; Female; Growth Hormone; Hypothalamus; Luteinizing Hormone; Morphine; Naltrexone; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Opioid; Thyrotropin	1980
Discriminative stimulus effects of prototype opiate receptor agonists in monkeys. European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1 Topics: Animals; Apomorphine; Cyclazocine; Ethylketocyclazocine; Female; Generalization, Stimulus; Haloperidol; Male; Models, Biological; Morphine; Naltrexone; Phenazocine; Prejudice; Receptors, Opioid; Saimiri	1980
Locomotor activity and antinociception after putative mu, kappa and sigma opioid receptor agonists in the rat: influence of dopaminergic agonists and antagonists. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:2 Topics: Analgesics; Animals; Apomorphine; Dopamine; Dopamine Antagonists; Drug Interactions; Male; Motor Activity; Naltrexone; Postural Balance; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Receptors, sigma; Spiperone	1981
Chronic stress enhances apomorphine-induced stereotyped behavior in mice: involvement of endogenous opioids. Brain research, 1984, Apr-23, Volume: 298, Issue:1 Topics: Animals; Apomorphine; Endorphins; Humans; Male; Mice; Mice, Inbred DBA; Naltrexone; Receptors, Dopamine; Stereotyped Behavior; Stress, Physiological	1984
Effects of naloxone and naltrexone on drug-induced hypothermia in mice. Neuropharmacology, 1984, Volume: 23, Issue:5 Topics: Animals; Apomorphine; Body Temperature; Body Temperature Regulation; Dopamine; Haloperidol; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotics; Pentobarbital	1984
Lack of effect of choline and narcotic antagonists upon apomorphine discrimination. European journal of pharmacology, 1980, Nov-21, Volume: 68, Issue:2 Topics: Animals; Apomorphine; Choline; Discrimination Learning; Haloperidol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Dopamine	1980
Enhancement of apomorphine-induced climbing in mice by reversible and irreversible narcotic antagonist drugs. Life sciences, 1981, Mar-23, Volume: 28, Issue:12 Topics: Animals; Apomorphine; Behavior, Animal; Drug Synergism; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Time Factors	1981
Blockade of morphine reward through the activation of kappa-opioid receptors in mice. Neuropharmacology, 1993, Volume: 32, Issue:12 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Apomorphine; Conditioning, Operant; Dopamine; Dynorphins; Homovanillic Acid; Injections, Subcutaneous; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motivation; Naltrexone; Peptide Fragments; Prosencephalon; Pyrrolidines; Receptors, Opioid, kappa; Reward	1993
Intrastriatal injection of opioid receptor agonists inhibits apomorphine-induced behavior in 6-hydroxydopamine-treated mice. European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3 Topics: Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Dopamine; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Mice; Naltrexone; Oxidopamine; Peptide Fragments; Receptors, Opioid	1995
A kappa opioid antagonist blocks sensitization in a rodent model of Parkinson's disease. Neuroreport, 1997, Feb-10, Volume: 8, Issue:3 Topics: Animals; Apomorphine; Functional Laterality; Hippocampus; Infusions, Parenteral; Levodopa; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Rotation	1997
Prevention of apomorphine- or cisplatin-induced emesis in the dog by a combination of methylnaltrexone and morphine. Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:4 Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Apomorphine; Cisplatin; Dogs; Drug Interactions; Drug Therapy, Combination; Emetics; Male; Morphine; Naltrexone; Narcotics; Quaternary Ammonium Compounds; Vomiting	1998
Behavioral activation induced by D(2)-like receptor stimulation during opiate withdrawal. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2 Topics: Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome	2000
Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 23, Issue:3 Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Immunohistochemistry; Lithium Chloride; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome	2000
Endomorphin-1, an endogenous mu-opioid receptor agonist, improves apomorphine-induced impairment of prepulse inhibition in mice. Peptides, 2003, Volume: 24, Issue:5 Topics: Animals; Apomorphine; Male; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, mu; Reflex, Startle	2003
Kappa opioid receptor activation disrupts prepulse inhibition of the acoustic startle in rats. Biological psychiatry, 2005, Jun-15, Volume: 57, Issue:12 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acoustic Stimulation; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Antipsychotic Agents; Apomorphine; Clozapine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Excitatory Amino Acid Antagonists; Haloperidol; Inhibition, Psychological; Male; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, kappa; Reflex, Startle	2005
Pharmacotherapy for erectile dysfunction. The journal of sexual medicine, 2004, Volume: 1, Issue:2 Topics: alpha-MSH; Apomorphine; Dopamine Agonists; Drug Therapy, Combination; Erectile Dysfunction; Humans; Isoquinolines; Male; Naltrexone; Naphthyridines; Neuroprotective Agents; Peptides, Cyclic; Phosphodiesterase Inhibitors; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Trazodone	2004