apomorphine has been researched along with naloxone in 158 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 119 (75.32) | 18.7374 |
1990's | 28 (17.72) | 18.2507 |
2000's | 5 (3.16) | 29.6817 |
2010's | 5 (3.16) | 24.3611 |
2020's | 1 (0.63) | 2.80 |
Authors | Studies |
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Campbell, BG; Kimes, AS; London, ED; Scheffel, U; Wilson, AA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Cott, J; Engel, J | 1 |
Billingsley, ML; Goldstein, JM; Kubena, RK; Malick, JB | 1 |
Hartley, EJ; McManus, C; Seeman, P | 1 |
Jacob, JJ; Tremblay, EC | 1 |
Bruinvels, J; Moleman, P; Versluis, DJ | 1 |
Bergmann, F; Chaimovitz, M; Pasternak, V | 1 |
Quock, RM | 2 |
Collier, HO; Francis, DL; McDonald-Gibson, WJ; Roy, AC; Saeed, SA | 1 |
Borison, RL; Diamond, BI | 1 |
Bläsig, J; Herz, A; Laschka, E; Schulz, R | 1 |
Donabedian, RK; Gold, MS; Redmond, DE | 1 |
Extein, I; Goodwin, FK; Lo, C; Schoenfeld, RI | 1 |
Cervantes, P; Guyda, H; Lal, S; Nair, NP; Pulman, J | 1 |
Donald, AG; Shah, NS | 1 |
Persson, SA | 1 |
Amir, S; Amit, Z; Blair, R | 1 |
Heinz, G; Jurna, I | 1 |
Lefebvre, RA; Willems, JL | 1 |
Ary, M; Cox, B; Lomax, P | 3 |
Pert, A; Sivit, C | 1 |
Kim, C; Van Loon, GR | 1 |
Margolin, DI; Moon, BH | 1 |
Muraki, T; Tokunaga, Y | 1 |
Ferri, S; Reina, R; Santagostino, A | 1 |
Cremer, H; Kuschinsky, K; Meseke, R; Ropte, H; Sontag, KH | 1 |
Harris, RA; Loh, HH; Snell, D; Way, EL | 1 |
Burks, TF; Stewart, JJ; Weisbrodt, NW | 2 |
Colpaert, FC; Janssen, PA; Niemegeers, CJ | 2 |
Iwamoto, ET; Loh, HH; Way, EL | 1 |
Gianutsos, G; Lal, H | 1 |
Harris, R; Loh, HH; Snell, D; Way, EL | 1 |
Ary, M; Lomax, P | 1 |
Brase, DA; Loh, HH; Tseng, LF | 1 |
Deacon, MA; Iorio, LC; Ryan, EA | 1 |
Buckett, WR; Shaw, JS | 1 |
Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H | 1 |
Celsen, B; Huppertz, A; Kuschinsky, K | 1 |
Sparber, SB; Takemori, AE; Tulunay, FC | 1 |
Henderson, GL; Westkaemper, R | 1 |
Cowan, A; Macfarlane, IR | 1 |
Argiolas, A; Gessa, GL; Melis, MR; Stancampiano, R | 1 |
Montastruc, JL; Montastruc, P; Rascol, O | 1 |
Barnes, NM; Bunce, KT; Naylor, RJ; Rudd, JA | 1 |
Kulkarni, SK; Verma, A | 2 |
Bonuccelli, U; Corsini, GU; Del Dotto, P; Muratorio, A; Piccini, P; Rossi, G | 1 |
Caine, SB; Geyer, MA; Swerdlow, NR | 1 |
Kiss, J; Lendvai, B; Sándor, A; Sándor, NT; Vizi, ES | 1 |
Belyi, VP; Kiyatkin, EA | 1 |
de la Cruz, F; Junquera, J; Russek, M | 1 |
Frey, HH; Hashem, A; Scherkl, R | 1 |
Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van de Buuse, M; van Wimersma Greidanus, TB | 1 |
Igarashi, J; Király, I; van Ree, JM | 1 |
Lang, IM; Marvig, J | 1 |
Martinez, RA; Schnur, P | 1 |
Artinián, J; Cancela, LM; Fulginiti, S | 1 |
Deviche, P | 1 |
Kontani, H; Koshiura, R | 1 |
Martin, JR; Takemori, AE | 3 |
Headley, PM; O'Shaughnessy, CT | 1 |
Blancquaert, JP; Lefebvre, RA; Willems, JL | 2 |
Cunningham, FJ; Howles, CM; Knight, PG | 1 |
Amalric, M; Koob, GF; Swerdlow, NR | 1 |
Martínez, JA; Milanés, MV; Vargas, ML | 1 |
Ignar, DM; Kuhn, CM | 1 |
Carvey, P; Goetz, CG; Klawans, HL; Paulseth, JE | 1 |
Amir, S | 1 |
Király, I; Van Ree, JM | 1 |
Szechtman, H | 2 |
Cooper, SJ; Gilbert, DB | 1 |
Quock, RM; Sadowski, JA | 1 |
Ben Natan, L; Costentin, J; Gonzales-Rios, F; Protais, P; Vlaiculescu, A | 1 |
Bantutova, I; Iakimova, K; Koleva, E; Ovcharova, R | 1 |
Barasi, S; Duggal, KN | 1 |
Artalejo, AR; García, AG; Montiel, C; Sánchez-García, P | 1 |
Fries, DS; Kouchich, FJ; Quock, RM | 1 |
Kuschinsky, K; Sontag, KH; Wand, P | 1 |
Hornykiewicz, O; Kuschinsky, K | 1 |
Bloom, AS; Quock, RM; Sadowski, JA | 1 |
Chiu, S; Mishra, RK | 1 |
Quock, RM; Welsh, TB | 1 |
Gonzalez, JP; Littler, ME; Sewell, RD | 1 |
Hartl, TJ; Lucas, TS; Quock, RM | 1 |
Leysen, JE; Van Gompel, P | 1 |
Andringa-Bakker, EA; de Rotte, AA; de Wied, D; van Ree, JM; van Wimersma Greidanus, TB | 1 |
Carlson, KR; Seeger, TF | 1 |
Gaffori, O; Kiraly, I; van Ree, JM | 1 |
Markovska, V; Petkov, V | 1 |
Clemens, JA; Shaar, CJ | 1 |
Anokhina, IP; Balashov, AM; Morozov, GV; Panchenko, LF; Vekshina, NL | 1 |
Kovács, GL; Penke, B; Szabó, G; Telegdy, G | 1 |
Bhargava, KP; Dixit, KS; Gupta, YK | 1 |
Andermann, F; Gloor, P; Quesney, LF | 1 |
Baggio, G; Ferrari, F | 3 |
Jones, RT; Joseph, MS; Keil, LC; Rowbotham, MC | 1 |
Cubells, J; Gardner, EL; Hirschhorn, ID; Hittner, D; Makman, MH | 1 |
Balsara, JJ; Burte, NP; Chandorkar, AG; Jadhav, JH; Nandal, NV | 1 |
Christ, H | 1 |
Herman, ZS; Kowalski, J; Przewłocki, R; Trzeciak, H | 1 |
Sakakibara, S | 1 |
Feigenbaum, J; Klawans, H; Moon, B; Yanai, J | 1 |
Becker, RA; Blask, DE; Champney, TH; Johnson, LY; Reiter, RJ; Vaughan, GM; Vaughan, MK | 1 |
Shuster, L; Thompson, ML; Weiss, J | 1 |
Chappel, SC; Norman, RL; Quadri, SK; Spies, HG | 1 |
Kogan, MJ; Mulè, SJ; Verebey, K | 1 |
Boschi, G; Launay, N; Rips, R | 1 |
Curell, J; Hitzemann, R; Hom, D; Loh, H | 1 |
Anokhina, IP | 1 |
Muscholl, E; Racké, K; Ritzel, H; Trapp, B | 1 |
Carson, PE; Feigenbaum, JJ; Klawans, HL; Moon, BH | 1 |
Brown, J; Handley, SL | 1 |
Adams, PM; Alston, C; Beauchamp, R | 1 |
Mintz, M; Myslobodsky, MS | 1 |
Schechter, MD | 1 |
Bogaert, MG; Lefebvre, RA; Willems, JL | 1 |
Lucas, TS; Quock, RM | 1 |
Booth, NH; Keith, JC; Kemppainen, RJ; Wilson, RC | 1 |
McMillen, BA | 1 |
Ibayashi, H; Kato, K; Motomatsu, T; Okajima, T | 1 |
Bastide, P; Coudert, P; Rubat, C; Tronche, P | 1 |
Gonzalez, M; Motles, E; Tetas, M | 1 |
Lapeyre-Mestre, M; Llau, ME; Montastruc, JL; Montastruc, P; Rascol, O; Senard, JM | 1 |
Holtzman, SG; Jones, DN | 1 |
Richardson, PJ; Sirinathsinghji, DJ; Vellucci, SV | 1 |
Mamanpush, SM; Rashidy-Pour, A; Zarrindast, MR | 1 |
Deschamps, SE; Druhan, JP; Stewart, J | 1 |
Gifford, AN; Wang, RY | 1 |
Miller, AD; Ruggiero, DA | 1 |
Gratton, A; Noel, MB | 1 |
Cho, DH; Jang, CG; Kang, SY; Kim, HS; Kong, JY; Oh, KW; Oh, S; Park, WK; Rheu, HM | 1 |
Argiolas, A; Iannucci, U; Melis, MR; Succu, S | 1 |
el-Kadi, AO; Sharif, SI | 1 |
Hu, WM; Kang, YM; Qiao, JT | 2 |
Farzin, D | 1 |
Ho, IK; Jang, C; Loh, HH; Ma, T; Park, Y; Tanaka, S | 1 |
Auff, E; Kotzailias, N; Sycha, T; Tribl, GG; Zeitlhofer, J | 1 |
Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
Kost, NV; Meshavkin, VK; Myasoedov, NF; Sokolov, OY; Zolotarev, YA; Zozulya, AA | 1 |
Bruno, V; Farcy, N; Karnik, V; Zamorano, C | 1 |
3 review(s) available for apomorphine and naloxone
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Catalepsy induced by body pinch: relation to stress-induced analgesia.
Topics: Analgesia; Animals; Apomorphine; Catalepsy; Endorphins; Haloperidol; Mice; Naloxone; Pain; Receptors, Dopamine; Stress, Physiological | 1986 |
Current Status of Pain Management in Parkinson's Disease.
Topics: Acetylcholine Release Inhibitors; Alanine; Analgesics; Antiparkinson Agents; Apomorphine; Benzylamines; Botulinum Toxins, Type A; Deep Brain Stimulation; Dopamine Agonists; Drug Combinations; Duloxetine Hydrochloride; Humans; Levodopa; Naloxone; Oxycodone; Pain; Pain Management; Pain Measurement; Pain Threshold; Parkinson Disease; Tetrahydronaphthalenes; Thiophenes | 2020 |
3 trial(s) available for apomorphine and naloxone
Article | Year |
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Naloxone partly counteracts apomorphine side effects.
Topics: Apomorphine; Double-Blind Method; Female; Humans; Male; Naloxone; Nausea; Parkinson Disease; Sleep Stages; Vomiting; Yawning | 1991 |
Failure of naloxone to reverse apomorphine effects in humans.
Topics: Adolescent; Adult; Apomorphine; Arginine Vasopressin; Blood Pressure; Drug Interactions; Growth Hormone; Heart Rate; Humans; Male; Naloxone; Nausea; Prolactin; Receptors, Opioid | 1983 |
Apomorphine in idiopathic restless legs syndrome: an exploratory study.
Topics: Administration, Oral; Adult; Aged; Apomorphine; Dopamine Agonists; Dopamine Antagonists; Drug Therapy, Combination; Electromyography; Female; Humans; Male; Metoclopramide; Middle Aged; Naloxone; Narcotic Antagonists; Restless Legs Syndrome; Treatment Outcome | 2005 |
152 other study(ies) available for apomorphine and naloxone
Article | Year |
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Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Guanidines; Guinea Pigs; Iodobenzenes; Male; Mice; Receptors, sigma; Tissue Distribution | 1992 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Suppression by GABAergic drugs of the locomotor stimulation induced by morphine, amphetamine, and apomorphine: evidence for both pre- and post-synaptic inhibition of catecholamine systems.
Topics: 4-Butyrolactone; Aminobutyrates; Aminooxyacetic Acid; Animals; Apomorphine; Brain; Clonidine; Corpus Striatum; Dextroamphetamine; Diencephalon; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Limbic System; Methyltyrosines; Mice; Morphine; Motor Activity; Naloxone; Norepinephrine; Reserpine; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1977 |
Evaluation of naloxone in laboratory tests predictive of clinical antipsychotic activity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Avoidance Learning; Clozapine; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Mice; Naloxone; Rats; Schizophrenia; Species Specificity; Stereotyped Behavior | 1977 |
Increased binding of [3H]apomorphine in caudate membranes after dopamine pretreatment in vitro.
Topics: Animals; Apomorphine; Cattle; Caudate Nucleus; Dioxanes; Dopamine; Haloperidol; In Vitro Techniques; Membranes; Naloxone; Phenyl Ethers | 1978 |
[Comparisons between the effects of apomorphine and naloxone in acutely dependent morphinized rats and mice (author's transl)].
Topics: Animals; Antipsychotic Agents; Apomorphine; Humans; Male; Methyltyrosines; Mice; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome; Time Factors | 1978 |
Is morphine-induced catalepsy related to activation of dopaminergic neurones?
Topics: Animals; Apomorphine; Catalepsy; Dopamine; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Naloxone; Neurons; Rats; Stereotyped Behavior | 1978 |
Dual action of morphine and related drugs on compulsive gnawing of rats.
Topics: Animals; Apomorphine; Behavior, Animal; Compulsive Behavior; Female; Fenclonine; Humans; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Stereotyped Behavior; Thalamic Nuclei | 1976 |
The potentiating effect of naloxone upon apomorphine-induced hyperthermia.
Topics: Animals; Apomorphine; Body Temperature; Cyproheptadine; Dextroamphetamine; Drug Synergism; Fenclonine; Haloperidol; Lysergic Acid Diethylamide; Male; Naloxone; Rabbits | 1977 |
Prostaglandins, cyclic AMP and the mechanism of opiate dependence.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Brain; Cattle; Codeine; Cyclic AMP; Humans; In Vitro Techniques; Male; Morphine; Morphine Dependence; Naloxone; Prostaglandins; Rats; Seminal Vesicles; Substance Withdrawal Syndrome; Substance-Related Disorders; Tissue Extracts | 1975 |
Enkephalins and nigrostriatal function.
Topics: Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Endorphins; Enkephalins; Hydroxydopamines; Levodopa; Male; Naloxone; Parkinson Disease; Parkinson Disease, Secondary; Phenethylamines; Rats; Receptors, Opioid; Reserpine; Substantia Nigra | 1978 |
Site of naloxone-precipitated opiate withdrawal dissociates from that at which apomorphine reinitiates this phenomenon.
Topics: Animals; Apomorphine; Clonidine; Humans; Injections, Intraventricular; Male; Naloxone; Rats; Receptors, Opioid; Substance Withdrawal Syndrome | 1978 |
The effects of opiate agonist and antagonist on serum prolactin in primates: possible role for endorphins in prolactin regulation.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Endorphins; Haloperidol; Haplorhini; Macaca; Male; Morphine; Naloxone; Prolactin; Receptors, Opioid | 1979 |
Dopamine-mediated behavior produced by the enkephalin analogue FK 33-824.
Topics: Animals; Apomorphine; Chlorpromazine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Haloperidol; Humans; Male; Naloxone; Rats; Receptors, Dopamine; Receptors, Opioid; Stereotyped Behavior | 1979 |
Effect of naloxone or levallorphan on serum prolactin concentrations and apomorphine-induced growth hormone secretion.
Topics: Apomorphine; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Levallorphan; Male; Naloxone; Prolactin; Receptors, Dopamine; Schizophrenia | 1979 |
Pharmacological effects and metabolic fate of levo-methadone during postnatal development in rat.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Blood Proteins; Brain; Methadone; Naloxone; Protein Binding; Rats; Subcellular Fractions; Tissue Distribution | 1979 |
Effect of morphine on the accumulation of DOPA after decarboxylase inhibition in the rat.
Topics: 4-Butyrolactone; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; DNA; Haloperidol; Male; Morphine; Naloxone; Rats; Receptors, Drug; Reserpine; Time Factors | 1979 |
Increased amphetamine potency following chronic naltrexone administration in rats.
Topics: Animals; Apomorphine; Dextroamphetamine; Drug Synergism; Male; Motor Activity; Naloxone; Naltrexone; Rats; Time Factors | 1979 |
Anti-nociceptive effect of morphine, opioid analgesics and haloperidol injected into the caudate nucleus of the rat.
Topics: Analgesics; Animals; Apomorphine; Caudate Nucleus; Female; Haloperidol; Injections; Male; Morphine; Naloxone; Narcotics; Rats | 1979 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting | 1979 |
Dopaminergic mechanisms in precipitated withdrawal in morphine-dependent rats.
Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Interactions; Humans; Male; Morphine Dependence; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Time Factors | 1977 |
Neuroanatomical focus for morphine and enkephalin-induced hypermotility.
Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Enkephalins; Haloperidol; Humans; Hyperkinesis; Injections; Injections, Intraperitoneal; Male; Morphine; Naloxone; Olfactory Bulb; Oligopeptides; Rats; Stimulation, Chemical; Time Factors | 1977 |
Dopaminergic mediation of beta-endorphin-induced catalepsy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Catalepsy; Corpus Striatum; Dopamine; Drug Synergism; Endorphins; Haloperidol; Humans; Male; Naloxone; Rats | 1978 |
Naloxone blockade of apomorphine-induced stereotyped behavior: interaction of endogenous opiates with dopamine.
Topics: Animals; Apomorphine; Behavior; Brain; Dopamine; Guinea Pigs; Humans; Male; Naloxone; Stereotyped Behavior | 1979 |
Effects of morphine on the serum prolactin levels of morphine-tolerant and nontolerant male rats and of the in vitro release of pituitary prolactin.
Topics: Animals; Apomorphine; Diphenhydramine; Dopamine; Drug Tolerance; Haloperidol; In Vitro Techniques; Male; Morphine; Naloxone; Pituitary Gland, Anterior; Prolactin; Rats | 1978 |
Dopamine and the depressant action of morphine on stimulated guinea-pig ileum.
Topics: Animals; Apomorphine; Dopamine; Electric Stimulation; Female; Guinea Pigs; Hydroxydopamines; Ileum; Male; Morphine; Muscle Contraction; Naloxone; Phentolamine; Propranolol | 1977 |
Specific action of narcotics on reflex activation of rat alpha-motoneurones.
Topics: Action Potentials; Animals; Apomorphine; Dextrorphan; Electric Stimulation; Levorphanol; Male; Morphine; Motor Neurons; Naloxone; Narcotics; Rats; Reflex; Spinal Cord | 1977 |
Behavioral interactions between naloxone and dopamine agonists.
Topics: Animals; Apomorphine; Behavior, Animal; Clonidine; Drug Synergism; Instinct; Male; Naloxone; Piperazines; Piribedil; Rats; Receptors, Dopamine | 1977 |
Intestinal stimulant response after intraventricular morphine in the conscious cat.
Topics: Action Potentials; Animals; Apomorphine; Cats; Epinephrine; Female; Injections, Intraventricular; Intestine, Small; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Stimulation, Chemical | 1977 |
Intestinal myoelectric activity after activation of central emetic mechanism.
Topics: Action Potentials; Animals; Apomorphine; Cats; Epinephrine; Female; Injections, Intraperitoneal; Injections, Intraventricular; Intestine, Small; Ketamine; Male; Morphine; Naloxone; Phentolamine; Vomiting | 1977 |
Changes in sensitivity to apomorphine during morphine dependence and withdrawal in rats.
Topics: Animals; Apomorphine; Dopamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1976 |
Fentanyl and apomorphine: asymmetrical generalization of discriminative stimulus properties.
Topics: Animals; Apomorphine; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Psychological; Haloperidol; Male; Naloxone; Rats; Receptors, Dopamine | 1976 |
Dopaminergic-cholinergic interactions in naloxone-induced circling in morphine-dependent rats with nigral lesions.
Topics: Animals; Apomorphine; Arecoline; Atropine; Behavior; Dopamine; Humans; Hydroxydopamines; Male; Morphine Dependence; Naloxone; Parasympathetic Nervous System; Rats; Stereotyped Behavior; Substance Withdrawal Syndrome; Substantia Nigra | 1976 |
Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone.
Topics: Aggression; Animals; Apomorphine; Drug Interactions; Humans; Male; Morphine; Naloxone; Parasympatholytics; Pilocarpine; Rats; Time Factors; Tranquilizing Agents | 1976 |
Behavioral interactions of apomorphine, clonidine and naloxone: possible presynatpic involvement.
Topics: Animals; Apomorphine; Behavior, Animal; Body Weight; Clonidine; Drug Interactions; Male; Naloxone; Rats; Reinforcement Schedule; Synapses | 1976 |
Dopaminergic sites involved in morphine withdrawal hypothermia.
Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Implants; Humans; Hypothalamus; Injections; Male; Morphine; Naloxone; Pimozide; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome | 1976 |
Dopaminergic influence on withdrawal jumping behavior in morphine-dependent mice.
Topics: Animals; Apomorphine; Brain; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Morphine Dependence; Motor Activity; Naloxone; Species Specificity; Substance Withdrawal Syndrome | 1976 |
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome | 1975 |
Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats.
Topics: Animals; Apomorphine; Dopamine; Humans; Hypothermia; Male; Morphine; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1975 |
Dopaminergic drugs antagonize the psychotomimetic effects of partial-agonist analgesics.
Topics: Amphetamine; Animals; Apomorphine; Behavior; Benztropine; Cyclazocine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Levodopa; Male; Motor Activity; Naloxone; Piribedil; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1975 |
Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal.
Topics: Aggression; Animals; Apomorphine; Dextroamphetamine; Humans; Male; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome | 1975 |
Studies on dopamine kinetics in rat brain tissue under the influence of morphine.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Imipramine; In Vitro Techniques; Kinetics; Morphine; Morphine Dependence; Naloxone; Potassium; Rats; Sensory Receptor Cells; Stereotyped Behavior | 1975 |
The effect of dopaminergic stimulation and blockade on the nociceptive and antinociceptive responses of mice.
Topics: Analgesics; Animals; Apomorphine; Depression, Chemical; Dopamine; Haloperidol; Levodopa; Male; Mice; Morphine; Naloxone; Pain; Pimozide; Reaction Time; Receptors, Drug; Stimulation, Chemical | 1975 |
Stereotypy following acute administration of l-alpha-acetylmethadol (LAAM) in the rat.
Topics: Amphetamine; Animals; Apomorphine; Behavior; Drug Interactions; Haloperidol; Humans; Male; Methadone; Methadyl Acetate; Methyltyrosines; Naloxone; Rats; Stereotyped Behavior | 1975 |
Effect of morphine antagonists on drug-induced hypothermia in mice and rats.
Topics: Animals; Antidepressive Agents; Apomorphine; Body Temperature; Cyclazocine; Desipramine; Dextroamphetamine; Diprenorphine; Drug Evaluation, Preclinical; Female; Male; Methyltyrosines; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxotremorine; Rats; Reserpine | 1976 |
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: site of action in the brain.
Topics: Analgesics; Animals; Apomorphine; Benzeneacetamides; Brain; Injections, Intraventricular; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Yawning | 1992 |
Naloxone or haloperidol but not yohimbine reverse apomorphine-induced respiratory depression.
Topics: Animals; Apomorphine; Dogs; Drug Interactions; Female; Haloperidol; Injections, Intravenous; Male; Naloxone; Respiratory Insufficiency; Vomiting; Yohimbine | 1992 |
The actions of fentanyl to inhibit drug-induced emesis.
Topics: Animals; Antiemetics; Apomorphine; Autoradiography; Brain Stem; Cisplatin; Copper; Copper Sulfate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Fentanyl; Ferrets; Male; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Vomiting | 1991 |
Alpha 2-adrenoceptor- and D2-dopamine receptor-mediated analgesic response of B-HT 920.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Azepines; Dopamine Agents; Female; Haloperidol; Male; Mice; Naloxone; Pain Measurement; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Dopamine D2 | 1991 |
Opiate-dopamine interactions in the neural substrates of acoustic startle gating in the rat.
Topics: Animals; Apomorphine; Dopamine; Heroin; Male; Naloxone; Narcotics; Neurons; Rats; Rats, Inbred Strains; Reflex, Startle | 1991 |
Naloxone enhances the release of acetylcholine from cholinergic interneurons of the striatum if the dopaminergic input is impaired.
Topics: Acetylcholine; Animals; Apomorphine; Cerebral Ventricles; Corpus Striatum; Dopamine; Injections, Intraventricular; Interneurons; Male; Naloxone; Neurotoxins; Oxidopamine; Rats; Rats, Inbred Strains; Reference Values; Sulpiride | 1991 |
Reinforcing properties of morphine chronically used in aversive life conditions: place-preference paradigm, long-term changes in behavioral reactivity.
Topics: Animals; Apomorphine; Behavior, Animal; Choice Behavior; Environment; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Restraint, Physical; Reward; Stress, Physiological; Time Factors | 1991 |
Ontogeny of the endorphinergic and dopaminergic modulation on the immobility reflex elicited by clamping in rats.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Endorphins; Female; Haloperidol; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reflex | 1990 |
Apomorphine-induced emesis in the dog--routes of administration, efficacy and synergism by naloxone.
Topics: Animals; Apomorphine; Dog Diseases; Dogs; Drug Synergism; Female; Injections, Intramuscular; Injections, Intravenous; Injections, Subcutaneous; Male; Naloxone; Vomiting | 1990 |
The effect of gamma-type endorphins on alpha-MSH release in the rat.
Topics: Animals; Antipsychotic Agents; Apomorphine; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; gamma-Endorphin; Haloperidol; Injections, Intraventricular; Male; Melanocyte-Stimulating Hormones; Naloxone; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains | 1985 |
Behavioral interaction between endogenous opioids, CCK-8 and dopaminergic systems in the nucleus accumbens of rats.
Topics: Animals; Apomorphine; Dopamine; Endorphins; gamma-Endorphin; Male; Motor Activity; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sincalide | 1986 |
Functional localization of specific receptors mediating gastrointestinal motor correlates of vomiting.
Topics: Animals; Apomorphine; Atropine; Copper; Copper Sulfate; Digestive System; Dogs; Domperidone; Female; Gastrointestinal Motility; Haloperidol; Hexamethonium; Hexamethonium Compounds; Male; Muscle Contraction; Naloxone; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Sincalide; Vomiting | 1989 |
Independent effects of morphine and apomorphine on stereotyped gnawing in the hamster.
Topics: Animals; Apomorphine; Cricetinae; Dose-Response Relationship, Drug; Female; Mesocricetus; Morphine; Naloxone; Stereotyped Behavior; Time Factors | 1989 |
Opioid influence on some aspects of stereotyped behavior induced by repeated amphetamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; beta-Endorphin; Corpus Striatum; Dopamine; Male; Morphine; Naloxone; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Stereotyped Behavior | 1988 |
Behavioral response to apomorphine and its interaction with opiates in domestic pigeons.
Topics: Animals; Apomorphine; Behavior, Animal; Columbidae; Dextrorphan; Dose-Response Relationship, Drug; Drug Interactions; Female; Levorphanol; Male; Naloxone; Receptors, Opioid; Stereoisomerism | 1985 |
The effects of morphine and morphine-related compounds on the rate of afferent discharges from the pulmonary receptors in bullfrog.
Topics: Animals; Apomorphine; Capsaicin; Dextromethorphan; In Vitro Techniques; Levallorphan; Lung; Morphine; Morphine Derivatives; Naloxone; Neurons, Afferent; Pentazocine; Rana catesbeiana; Receptors, Opioid | 1985 |
Increased sensitivity to dopamine agonists following a single dose of morphine or levorphanol in mice.
Topics: Animals; Apomorphine; Brain; Brain Stem; Cerebral Cortex; Chlorides; Corpus Striatum; Dextrorphan; Drug Synergism; Hippocampus; Levorphanol; Lithium; Lithium Chloride; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotics; Receptors, Dopamine; Spiperone | 1985 |
The use of cyclic AMP efflux studies in attempts to determine the effects of morphine on cyclic AMP formation in striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Benzazepines; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; In Vitro Techniques; Morphine; Naloxone; Rats | 1986 |
Emetic and antiemetic effects of opioids in the dog.
Topics: Animals; Antiemetics; Apomorphine; Benzomorphans; Copper; Copper Sulfate; Dogs; Emetics; Female; Hypnotics and Sedatives; Male; Naloxone; Narcotics; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1986 |
Evidence that opioid peptides and dopamine participate in the suckling-induced release of prolactin in the ewe.
Topics: Animals; Apomorphine; Dopamine; Endorphins; Female; Lactation; Metoclopramide; Naloxone; Pituitary Gland, Anterior; Pregnancy; Prolactin; Sheep; Thyrotropin-Releasing Hormone | 1986 |
Nucleus accumbens opiate-dopamine interactions and locomotor activation in the rat: evidence for a pre-synaptic locus.
Topics: Amphetamine; Animals; Apomorphine; Dopamine; Hydroxydopamines; Male; Motor Activity; Naloxone; Nucleus Accumbens; Oxidopamine; Rats; Rats, Inbred Strains; Septal Nuclei; Synapses | 1987 |
[Interaction of opioid peptides and the dopaminergic system in the myenteric plexus of the guniea pig ileum].
Topics: Animals; Apomorphine; Bromocriptine; Drug Interactions; Endorphins; Guinea Pigs; Haloperidol; Hydroxydopamines; Ileum; In Vitro Techniques; Myenteric Plexus; Naloxone; Oxidopamine; Receptors, Dopamine | 1987 |
Relative ontogeny of opioid and catecholaminergic regulation of thyrotropin secretion in the rat.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Body Temperature; Catecholamines; Clonidine; Cold Temperature; Corticosterone; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1988 |
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea Pigs; Haloperidol; Lisuride; Morphine; Myoclonus; Naloxone; Scopolamine; Tremorine | 1986 |
Behavioral evidence for the involvement of endogenous opioids in the interaction between cholecystokinin and brain dopamine systems.
Topics: Animals; Apomorphine; Dopamine; Endorphins; Haloperidol; Male; Motor Activity; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sincalide | 1987 |
Modification of the development of acute opiate tolerance by increased dopamine receptor sensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Drug Interactions; Drug Tolerance; Levorphanol; Lithium; Male; Mice; Morphine; Naloxone; Narcotics; Opioid-Related Disorders; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1987 |
Chronically administered morphine increases dopamine receptor sensitivity in mice.
Topics: Analgesia; Animals; Apomorphine; Behavior, Animal; Binding Sites; Brain; Drug Implants; Drug Tolerance; Hypothermia; Lithium; Male; Mice; Morphine; Naloxone; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1986 |
Effects of pretreatment with naloxone on behaviours induced by a small dose of apomorphine.
Topics: Animals; Apomorphine; Grooming; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1986 |
Naloxone antagonizes the hyperdipsic effect of sulpiride in a salt-preference test in male and female rats.
Topics: Animals; Apomorphine; Drinking Behavior; Drug Interactions; Female; Food Preferences; Male; Naloxone; Rats; Receptors, Dopamine; Sodium Chloride; Sulpiride; Thirst; Water Deprivation | 1986 |
Influence of naloxone upon apomorphine-induced rotational behavior in rats with electrolytic versus chemolytical lesions of the substantia nigra.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Drug Synergism; Electrolysis; Male; Naloxone; Rats; Rats, Inbred Strains; Rotation; Stereotyped Behavior; Substantia Nigra | 1986 |
Dissociated effects of apomorphine on various nociceptive responses in mice.
Topics: Analgesics; Animals; Apomorphine; Body Temperature; Domperidone; Dopamine; Haloperidol; Male; Mice; Naloxone; Pain Measurement; Sulpiride | 1986 |
[Effect on morphine hyperthermia of dopaminergic agents].
Topics: Animals; Apomorphine; Body Temperature; Bromocriptine; Drug Interactions; Fever; Haloperidol; Male; Methotrimeprazine; Morphine; Naloxone; Rats; Rats, Inbred Strains; Rectum; Time Factors | 1985 |
The effect of local and systemic application of dopaminergic agents on tail flick latency in the rat.
Topics: Analgesics; Animals; Apomorphine; Drug Interactions; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Dopamine; Reflex, Monosynaptic; Sulpiride | 1985 |
Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog.
Topics: Animals; Apomorphine; Brain; Chemoreceptor Cells; Dogs; Domperidone; Female; Injections, Intravenous; Injections, Intraventricular; Morphine; Naloxone; Pressure; Stomach; Vomiting | 1985 |
A dopaminergic receptor modulates catecholamine release from the cat adrenal gland.
Topics: Adrenal Glands; Adrenal Medulla; Animals; Apomorphine; Benzamides; Catecholamines; Cats; Dopamine; Female; Haloperidol; Male; Naloxone; Nicotine; Phentolamine; Receptors, Dopamine | 1985 |
Narcotic antagonist potentiation of apomorphine drug effect: a stereospecific, centrally mediated drug action.
Topics: Animals; Apomorphine; Drug Synergism; Exploratory Behavior; Humans; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Stereoisomerism; Stereotyped Behavior | 1985 |
Morphine-induced muscular rigidity in rats.
Topics: Animals; Apomorphine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Electromyography; Male; Morphine; Muscle Rigidity; Naloxone; Narcotic Antagonists; Rats; Time Factors | 1973 |
Morphine catalepsy in the rat: relation to striatal dopamine metabolism.
Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains | 1972 |
Possible noradrenergic involvement in naloxone potentiation of apomorphine-induced stereotypic climbing in mice.
Topics: alpha-Methyltyrosine; Animals; Apomorphine; Brain; Ditiocarb; Dopamine; Drug Synergism; Humans; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Naloxone; Norepinephrine; Reserpine; Stereotyped Behavior | 1984 |
Effects of dopaminergic and cholinergic drugs. naloxone and l-prolyl-leucyl-glycinamide on LSD-induced catalepsy.
Topics: Animals; Apomorphine; Catalepsy; Dose-Response Relationship, Drug; Humans; Levodopa; Lysergic Acid Diethylamide; Male; MSH Release-Inhibiting Hormone; Naloxone; Parasympathomimetics; Rats; Synaptic Transmission; Time Factors | 1980 |
Potentiation of apomorphine-induced rotational behaviour by naloxone.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Drug Synergism; Humans; Male; Naloxone; Rats; Stereotyped Behavior; Substantia Nigra | 1981 |
Stereoselective opiate antagonist induced hyperalgesia: evidence for a dopaminergic involvement.
Topics: Animals; Apomorphine; Dopamine; Injections, Intraventricular; Levodopa; Male; Mice; Naloxone; Narcotic Antagonists; Nomifensine; Pain; Tetrabenazine | 1982 |
Potentiation of apomorphine-induced stereotypies by naloxone and L-prolyl-L-leucyl-glycinamide.
Topics: Animals; Apomorphine; Drug Synergism; Humans; Kinetics; Male; Mice; Mice, Inbred ICR; MSH Release-Inhibiting Hormone; Naloxone; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1983 |
Kinetics of brain receptor binding inhibition by endogenous macromolecular substances [proceedings].
Topics: Animals; Apomorphine; Brain; Fentanyl; Haloperidol; Kinetics; Naloxone; Rats; Receptors, Drug; Receptors, Opioid; Receptors, Serotonin | 1980 |
The influence of beta-LPH fragments on alpha-MSH release: the involvement of a dopaminergic system.
Topics: alpha-Endorphin; Animals; Apomorphine; beta-Endorphin; Brain Chemistry; Dopamine; Endorphins; gamma-Endorphin; Haloperidol; Male; Melanocyte-Stimulating Hormones; Naloxone; Peptide Fragments; Rats; Rats, Inbred Strains | 1981 |
Interaction of opiates with dopamine receptors: receptor binding and behavioral assays.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butaclamol; Dibenzocycloheptenes; Haloperidol; Kinetics; Male; Methadone; Morphine; Naloxone; Rats; Receptors, Dopamine; Spiperone | 1982 |
gamma-Endorphin and N alpha-acetyl-gamma-endorphin interfere with distinct dopaminergic systems in the nucleus accumbens via opioid and non-opioid mechanisms.
Topics: Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Dopamine; Endorphins; gamma-Endorphin; Humans; Male; Motor Activity; Naloxone; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Stereotyped Behavior | 1984 |
Participation of serotoninergic, GABA-ergic and opiate mechanisms in the genesis of amphetamine stereotypy.
Topics: Amphetamine; Animals; Apomorphine; Atropine; Endorphins; Fenclonine; gamma-Aminobutyric Acid; Humans; Male; Naloxone; Quipazine; Rats; Serotonin; Stereotyped Behavior | 1984 |
The effects of opiate agonists on growth hormone and prolactin release in rats.
Topics: Animals; Apomorphine; Enkephalins; Growth Hormone; Male; Methadone; Morphine; Naloxone; Naltrexone; Parasympathomimetics; Prolactin; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Opioid; Secretory Rate | 1980 |
[Effect of apomorphine on rat brain opiate receptors].
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Enkephalins; Male; Naloxone; Rats; Receptors, Opioid; Sodium Chloride | 1980 |
Effects of cholecystokinin octapeptide on striatal dopamine metabolism and on apomorphine-induced stereotyped cage-climbing in mice.
Topics: alpha-Methyltyrosine; Animals; Apomorphine; Cholecystokinin; Corpus Striatum; Dopamine; Drug Interactions; Haloperidol; Humans; Male; Methyltyrosines; Mice; Naloxone; Receptors, Dopamine; Sincalide; Stereotyped Behavior | 1981 |
Enkephalin receptors in the emetic chemoreceptor trigger zone of the dog.
Topics: Animals; Apomorphine; Chemoreceptor Cells; Dogs; Emetics; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Naloxone; Receptors, Opioid | 1981 |
Dopaminergic mechanism in generalized photosensitive epilepsy.
Topics: Adolescent; Adult; Apomorphine; Dopamine; Electrophysiology; Epilepsy; Female; Humans; Middle Aged; Naloxone; Photic Stimulation; Receptors, Dopamine; Receptors, Opioid | 1981 |
Potentiation of the aphrodisiac effect of N-n-propyl-norapomorphine by naloxone.
Topics: Adrenocorticotropic Hormone; Animals; Aphrodisiacs; Apomorphine; Dose-Response Relationship, Drug; Drug Synergism; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Naloxone potentiation of apomorphine-induced stereotypic climbing in mice and interaction with mu-, sigma- and kappa-opiate drugs.
Topics: Animals; Apomorphine; Drug Synergism; Humans; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotics; Receptors, Opioid; Stereotyped Behavior | 1982 |
Evidence for a role of endogenous opioids in the nigrostriatal system: influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Endorphins; Humans; Hydroxydopamines; Male; Morphine; Naloxone; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1983 |
Effects of naloxone on methamphetamine and apomorphine stereotypy and on haloperidol catalepsy in rats.
Topics: Animals; Apomorphine; Catalepsy; Haloperidol; Humans; Male; Methamphetamine; Naloxone; Rats; Stereotyped Behavior | 1984 |
Behavioral effects of TRH, 3-Me-His2-TRH and naloxone in Hemichromis bimaculatus.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Fishes; Humans; Naloxone; Prolactin; Pyrrolidonecarboxylic Acid; Thyrotropin-Releasing Hormone; Time Factors | 1984 |
Enkephalin content in rat striatum during prolonged treatment with fluphenazine.
Topics: Animals; Apomorphine; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Fluphenazine; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1984 |
Timing of yawns induced by a small dose of apomorphine and its alteration by naloxone.
Topics: Animals; Apomorphine; Male; Naloxone; Rats; Rats, Inbred Strains; Reflex; Respiration | 1984 |
[Pharmacological action of eptazocine (l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine). Effects of eptazocine on spontaneous movements].
Topics: Analgesics; Animals; Apomorphine; Cyclazocine; Disulfiram; Haloperidol; Male; Morphine; Movement; Naloxone; Pentazocine; Rats; Rats, Inbred Strains | 1983 |
Effect of naloxone and morphine on dopamine agonist-induced stereotypy in rats and guinea pigs.
Topics: Amphetamine; Animals; Apomorphine; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior | 1983 |
Opioid and dopamine involvement in prolactin release induced by arginine vasotocin and vasopressin in the male rat.
Topics: Animals; Apomorphine; Arginine Vasopressin; Dopamine; Endorphins; Hypothalamo-Hypophyseal System; Male; Methysergide; Naloxone; Prolactin; Rats; Rats, Inbred Strains; Vasopressins | 1984 |
Effects of naloxone and naltrexone on drug-induced hypothermia in mice.
Topics: Animals; Apomorphine; Body Temperature; Body Temperature Regulation; Dopamine; Haloperidol; Male; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotics; Pentobarbital | 1984 |
Dopaminergic and opioid compounds. Effects on prolactin and LH release after electrical stimulation of the hypothalamus in ovariectomized rhesus monkeys.
Topics: Animals; Apomorphine; Castration; Dopamine; Electric Stimulation; Endorphins; Female; Haplorhini; Hypothalamus; Luteinizing Hormone; Macaca mulatta; Naloxone; Prolactin | 1980 |
Phencyclidine-induced stereotype in rats: effects of methadone, apomorphine, and naloxone.
Topics: Animals; Apomorphine; Brain Chemistry; Disease Models, Animal; Humans; Male; Methadone; Motor Activity; Naloxone; Phencyclidine; Psychoses, Substance-Induced; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1981 |
Influence of lisuride on morphine withdrawal signs in the rat: a dopamine-mimetic effect.
Topics: Aggression; Animals; Apomorphine; Dopamine; Ergolines; Haloperidol; Humans; Lisuride; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Sulpiride | 1982 |
Induction of wet-dog shakes by intracerebral 'acid' TRH in rats.
Topics: Animals; Apomorphine; Cyproheptadine; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Movement Disorders; Naloxone; Phentolamine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1980 |
Effects of naloxone on d-amphetamine- and apomorphine-induced behavior.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain; Dextroamphetamine; Dopamine; Drug Interactions; Humans; Male; Naloxone; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior | 1982 |
[Various aspects of the interaction between the dopamine and opiate systems in schizophrenia].
Topics: Apomorphine; Dopamine; Humans; Naloxone; Schizophrenia | 1982 |
Dopaminergic modulation of evoked vasopressin release from the isolated neurohypophysis of the rat. Possible involvement of endogenous opioids.
Topics: Animals; Apomorphine; Bromocriptine; Dopamine; Electric Stimulation; Endorphins; Female; Flupenthixol; In Vitro Techniques; Naloxone; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Tetrodotoxin; Vasopressins | 1982 |
Reinforcement with naloxone of N-n-propylnorapomorphine (NPA) capability for stimulating male rat copulatory behavior.
Topics: Animals; Apomorphine; Copulation; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1982 |
The role of dopaminergic mechanisms in naloxone-induced inhibition of apomorphine-induced stereotyped behavior.
Topics: Animals; Apomorphine; Behavior; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Humans; Male; Naloxone; Rats; Stereotyped Behavior; Time Factors | 1980 |
The development of catalepsy in drug-free mice on repeated testing.
Topics: Animals; Apomorphine; Atropine; Behavior, Animal; Catalepsy; Handling, Psychological; Humans; Male; Mice; Mice, Inbred Strains; Naloxone; Posture; Time Factors | 1980 |
Potentiation of apomorphine and D-amphetamine effects by naloxone.
Topics: Animals; Apomorphine; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Kinetics; Locomotion; Male; Naloxone; Rats; Stereotyped Behavior | 1981 |
Postictal behavioral arrest in the rat: "catalepsy" or "catatonia"?
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Catatonia; Electric Stimulation; Female; Haloperidol; Humans; Naloxone; Rats; Seizures | 1981 |
Lack of effect of choline and narcotic antagonists upon apomorphine discrimination.
Topics: Animals; Apomorphine; Choline; Discrimination Learning; Haloperidol; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Receptors, Dopamine | 1980 |
Gastric relaxation and vomiting by apomorphine, morphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Dogs; Dopamine Antagonists; Drug Interactions; Female; Fentanyl; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Pressure; Stomach; Vomiting | 1981 |
Enhancement of apomorphine-induced climbing in mice by reversible and irreversible narcotic antagonist drugs.
Topics: Animals; Apomorphine; Behavior, Animal; Drug Synergism; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Nitrogen Mustard Compounds; Time Factors | 1981 |
Failure of naloxone to prevent the emetic activity of apomorphine in dogs.
Topics: Animals; Apomorphine; Dogs; Droperidol; Female; Fentanyl; Haloperidol; Injections, Intravenous; Male; Naloxone; Time Factors; Vomiting | 1981 |
On the mechanism of morphine action on rat striatal dopamine metabolsim.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Haloperidol; In Vitro Techniques; Morphine; Naloxone; Rats | 1980 |
Naloxone inhibits prolactin and growth hormone release induced by intracellular glucopenia in the rats.
Topics: Animals; Apomorphine; Deoxy Sugars; Deoxyglucose; Growth Hormone; Hypoglycemia; Male; Naloxone; Prolactin; Rats | 1980 |
Factors regulating drug cue sensitivity: the effect of training dose in fentanyl-saline discrimination.
Topics: Animals; Apomorphine; Cues; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Fentanyl; Generalization, Stimulus; Male; Morphine; Naloxone; Rats; Research Design; Sodium Chloride | 1980 |
Role of D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptors in morphine tolerance and dependence in mice.
Topics: Animals; Apomorphine; Azepines; Bromocriptine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Tolerance; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1995 |
Behavioural profile of two potential antidepressant pyridazine derivatives including arylpiperazinyl moieties in their structure, in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blepharoptosis; Citalopram; Clomipramine; Drug Interactions; Fluoxetine; Hypothermia; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Models, Molecular; Motor Activity; Naloxone; Piperazines; Pyridazines; Reserpine; Structure-Activity Relationship; Swimming; Trazodone; Yohimbine | 1995 |
Effects of naloxone on the behaviors evoked by amphetamine and apomorphine in adult cats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Cats; Drug Interactions; Electroencephalography; Fear; Female; Motor Activity; Naloxone; Smell | 1995 |
Naloxone does not prevent apomorphine-induced emesis or hypotension in dogs.
Topics: Anesthetics; Animals; Apomorphine; Blood Pressure; Chloralose; Dogs; Female; Heart Rate; Hypotension; Male; Naloxone; Vomiting | 1994 |
Influence of naloxone upon motor activity induced by psychomotor stimulant drugs.
Topics: Animals; Apomorphine; Caffeine; Catecholamines; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Male; Motor Activity; Naloxone; Neurotransmitter Uptake Inhibitors; Rats; Rats, Sprague-Dawley; Scopolamine | 1994 |
Adenosine A2 receptor regulation of apomorphine-induced turning in rats with unilateral striatal dopamine denervation.
Topics: Acetylcholine; Adenosine; Animals; Antihypertensive Agents; Apomorphine; Atropine; Brain; Dopamine; Female; Naloxone; Neostriatum; Oxidopamine; Phenethylamines; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Sympathectomy, Chemical | 1993 |
Morphine inhibits dopaminergic and cholinergic induced ejaculation in rats.
Topics: Animals; Apomorphine; Atropine; Cholinergic Agents; Dopamine Agents; Ejaculation; Ergolines; Male; Morphine; Naloxone; Physostigmine; Pilocarpine; Quinpirole; Rats; Sulpiride | 1994 |
D-amphetamine-like stimulus properties are produced by morphine injections into the ventral tegmental area but not into the nucleus accumbens.
Topics: Animals; Apomorphine; Cues; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dopamine; Generalization, Stimulus; Injections; Male; Morphine; Motor Activity; Naloxone; Neurons; Nucleus Accumbens; Rats; Receptors, Opioid, mu; Reinforcement Schedule; Ventral Tegmental Area | 1993 |
The effect of 5-HT3 receptor antagonists on the morphine-induced excitation of A10 dopamine cells: electrophysiological studies.
Topics: Animals; Apomorphine; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Evoked Potentials; Indoles; Male; Morphine; Naloxone; Neurons; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tegmentum Mesencephali | 1994 |
Emetic reflex arc revealed by expression of the immediate-early gene c-fos in the cat.
Topics: Animals; Apomorphine; Brain Stem; Cats; Cervical Plexus; Cisplatin; Decerebrate State; Emetics; Gene Expression; Genes, fos; Genes, Immediate-Early; Lobeline; Medulla Oblongata; Naloxone; Neurons; Organ Specificity; Phrenic Nerve; Proto-Oncogene Proteins c-fos; Protoveratrines; Reflex; Spinal Cord; Vomiting | 1994 |
Electrochemical evidence of increased dopamine transmission in prefrontal cortex and nucleus accumbens elicited by ventral tegmental mu-opioid receptor activation in freely behaving rats.
Topics: Animals; Apomorphine; Behavior, Animal; Dopamine; Electrochemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Naloxone; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Inbred Strains; Receptors, Opioid, mu; Stereotyped Behavior; Synaptic Transmission; Tegmentum Mesencephali | 1995 |
Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice.
Topics: Animals; Apomorphine; Cocaine; Conditioning, Operant; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Stereotyped Behavior | 1997 |
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: involvement of nitric oxide.
Topics: Analgesics, Opioid; Animals; Apomorphine; Benzeneacetamides; Dopamine Agonists; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nitrates; Nitric Oxide; Nitrites; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Yawning | 1997 |
The role of dopamine in the expression of morphine withdrawal.
Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Hypothermia; Levodopa; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxidopamine; Substance Withdrawal Syndrome | 1998 |
Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Dopamine Agonists; Endorphins; Female; Glyburide; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Pain; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reaction Time; Spinal Cord | 1998 |
Involvement of endogenous opioids and ATP-sensitive potassium channels in the mediation of apomorphine-induced antinociception at the spinal level: a study using EMG planimetry of flexor reflex in rats.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Dopamine Agonists; Electromyography; Glyburide; Hypoglycemic Agents; Injections, Spinal; Male; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Potassium Channels; Rats; Rats, Wistar; Reflex; Spinal Cord | 1999 |
Modification of naloxone-induced withdrawal signs by dextromethorphan in morphine-dependent mice.
Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Dextromethorphan; Domperidone; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Grooming; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Sulpiride | 1999 |
Involvement of mu-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: studies using mu-opioid receptor gene knockout mice.
Topics: Analgesics, Opioid; Animals; Apomorphine; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Haloperidol; Mice; Mice, Knockout; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu | 2000 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Naloxone-blocked depriming effect of anxiolytic selank on apomorphine-induced behavioral manifestations of hyperfunction of dopamine system.
Topics: Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Dopamine; Enkephalin, Leucine-2-Alanine; Male; Mice; Naloxone; Olanzapine; Oligopeptides; Receptors, Dopamine D2; Receptors, Opioid, mu; Spiperone; Stereotyped Behavior | 2006 |