apomorphine has been researched along with morphine in 263 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 197 (74.90) | 18.7374 |
| 1990's | 33 (12.55) | 18.2507 |
| 2000's | 20 (7.60) | 29.6817 |
| 2010's | 10 (3.80) | 24.3611 |
| 2020's | 3 (1.14) | 2.80 |
| Authors | Studies |
|---|---|
| Agnati, L; Dafeldecker, WP; Fuxe, K; Guarino, J; Kosersky, DS; Neumeyer, JL; Reinhard, JF | 1 |
| Aceto, MD; Bowman, ER; Frigeni, V; Harris, LS; Iorio, MA; May, EL | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Cowan, A; Dettmar, PW; Walter, DS | 1 |
| Erzin-Waters, C; Muller, P; Seeman, P | 1 |
| Korf, J; Westerink, BH | 3 |
| Janssen, PA; Niemegeers, CJ; Schellekens, KH; Van Bever, WF | 1 |
| Lal, S; Sourkes, TL; Symes, AL | 1 |
| Cott, J; Engel, J | 1 |
| Dunai-Kovács, Z; Székely, JI | 1 |
| Di Chiara, G; Gessa, GL; Longoni, R; Mulas, A; Porceddu, ML; Vargiu, L | 1 |
| Andén, NE; Grabowska-Andén, M | 1 |
| Chan, SH | 1 |
| Horsman, L; Pullar, IA; Tye, NC; Wright, FC | 1 |
| Abdel-Halim, MS; Anggård, E; Sjöquist, B | 1 |
| Almasi, J; Carlson, KR | 2 |
| Bruinvels, J; Moleman, P; Versluis, DJ | 1 |
| Bergmann, F; Chaimovitz, M; Pasternak, V | 1 |
| Cheney, DL; Costa, E; Racagni, G; Zsilla, G | 1 |
| Kuschinsky, K | 2 |
| Collier, HO; Francis, DL; McDonald-Gibson, WJ; Roy, AC; Saeed, SA | 1 |
| Oliverio, A; Racagni, G; Spano, PF; Trabucchi, M | 1 |
| Biggio, G; Costa, E; Guidotti, A | 1 |
| Gold, T; Kesner, RP; Priano, DJ | 1 |
| Donabedian, RK; Gold, MS; Redmond, DE | 1 |
| Gianutsos, G; Lal, H; Puri, SK | 1 |
| Carenzi, A; Costa, E; Guidotti, A; Revuelta, A | 1 |
| Dent, R; Guyda, H; Tolis, G | 1 |
| Bhargava, HN; Flexner, LB; Ritzmann, RF; Walter, R | 1 |
| Chau-Pham, T; Dewey, WL; Martin, BR; Prnage, AJ | 1 |
| Golembiowska, K; Mogilnicka, E; Scheel-Krüger, J | 1 |
| Persson, SA | 1 |
| Grandison, L; Guidotti, A | 1 |
| Eshel, Y; Korczyn, AD | 1 |
| Heinz, G; Jurna, I | 1 |
| Lefebvre, RA; Willems, JL | 1 |
| Bruinvels, J; Moleman, P | 1 |
| Brown, G; Brown, W; Drawbaugh, R; Hynes, M; Lal, H | 1 |
| Halliwell, JV; Kumar, R | 2 |
| Cox, RD; Glick, SD | 2 |
| Pert, A; Sivit, C | 1 |
| Costentin, J; de la Baume, S; Marçais, H; Patey, G; Protais, P; Schwartz, JC | 1 |
| Arnt, J; Scheel-Krüger, J | 1 |
| Kharalambieva, M; Micheva, M; Raĭnova, L; Staneva-Stoĭcheva, D | 1 |
| Strömbom, U; Svensson, TH | 1 |
| Appel, JB; Hernandez, LL; Holohean, AM | 2 |
| Muraki, T; Tokunaga, Y | 1 |
| Cheney, DL; Costa, E; Moroni, F; Peralta, E | 1 |
| Overstreet, DH; Smee, ML | 1 |
| Ferri, S; Reina, R; Santagostino, A | 1 |
| Cremer, H; Kuschinsky, K; Meseke, R; Ropte, H; Sontag, KH | 1 |
| Bogaert, MG; Buylaert, WA; Willems, JL | 1 |
| Cuparencu, B; Sandor, V | 1 |
| Burks, TF; Stewart, JJ; Weisbrodt, NW | 4 |
| Broekkamp, CL; Pijnenburg, AJ; van Rossum, JM | 1 |
| Clouet, DH; Iwatsubo, K | 1 |
| Fuxe, K; Hole, K; Jonsson, G | 1 |
| Eades, CG; Gilbert, PE; Huppler, RE; Martin, WR; Thompson, JA | 1 |
| Gianutsos, G; Lal, H | 1 |
| Gianutsos, G; Hynes, MD; Lal, H | 1 |
| Ary, IE; Atkinson, ER; Battista, SP; Dewey, WL; Harris, LS; Richardson, DG | 1 |
| Overstreet, DH; Smee, ML; Woolston, ME | 1 |
| Ary, M; Lomax, P | 1 |
| Calil, HM; Silva, MT | 1 |
| Glick, SD | 1 |
| Deacon, MA; Iorio, LC; Ryan, EA | 1 |
| Ary, M; Cox, B; Lomax, P | 1 |
| Poignant, JC; Rismondo, N | 1 |
| Celsen, B; Huppertz, A; Kuschinsky, K | 1 |
| Sparber, SB; Takemori, AE; Tulunay, FC | 1 |
| Guyda, H; Hickey, J; Tolis, G | 1 |
| Canevari, R; Gressier, H; Petitjean, M; Poignant, JC; Regnier, G | 1 |
| Cowan, A; Macfarlane, IR | 1 |
| Argiolas, A; Gessa, GL; Melis, MR; Stancampiano, R | 1 |
| Parker, LA | 1 |
| Baraban, JM; Bhat, RV; Cole, AJ; Worley, PF | 1 |
| Argiolas, A | 1 |
| Barnes, NM; Bunce, KT; Naylor, RJ; Rudd, JA | 1 |
| Cory-Slechta, DA; Widzowski, DV | 1 |
| Franklin, KB; Morgan, MJ | 1 |
| Belyi, VP; Kiyatkin, EA | 1 |
| Kiyatkin, EA; Zhukov, VN | 1 |
| Hasegawa, Y; Kurachi, M; Otomo, S | 1 |
| Ceresoli, G; Groppetti, A; Mandelli, V; Parenti, M | 1 |
| Cai, B; Matsumoto, K; Nakamura, S; Watanabe, H | 1 |
| de la Cruz, F; Junquera, J; Russek, M | 1 |
| Daval, G; Fattaccini, CM; Gozlan, H; Hamon, M; Spampinato, U | 1 |
| Banerjee, AK; Dhasmana, KM; Erdmann, W; Parmar, SS; Salzman, SK; Zhu, YN | 1 |
| Martinez, RA; Schnur, P | 1 |
| Bhargava, HN; Das, S | 1 |
| Havemann, U | 1 |
| Gupta, GP; Gupta, ML; Gupta, TK; Nath, R | 1 |
| Chugh, A; Gupta, YK; Seth, SD | 1 |
| Artinián, J; Cancela, LM; Fulginiti, S | 1 |
| Kontani, H; Koshiura, R | 1 |
| Martin, JR; Takemori, AE | 4 |
| Headley, PM; O'Shaughnessy, CT | 1 |
| Ignar, DM; Kuhn, CM | 1 |
| Gupta, PK; Hung, CT; Young, M | 1 |
| Carvey, P; Goetz, CG; Klawans, HL; Paulseth, JE | 1 |
| Kamata, K; Kameyama, T; Noma, S; Ogawa, K | 1 |
| Fields, GN; Johnston, JP; Philp, RB | 1 |
| Gottschall, PE; Meites, J | 1 |
| Kuschinsky, K; Möller, HG | 1 |
| Bantutova, I; Iakimova, K; Koleva, E; Ovcharova, R | 1 |
| Brus, R; Gmerczyński, T; Makowska, B; Stanosek, B | 1 |
| Järbe, TU; Swedberg, MD | 1 |
| Gottschall, PE; Meites, J; Sarkar, DK | 1 |
| Blancquaert, JP; Lefebvre, RA; Willems, JL | 2 |
| Kamata, K; Kameyama, T; Ogawa, K | 1 |
| Bastos, ML; Jukofsky, D; Mulé, SJ | 1 |
| McKenzie, GM; Sadof, M | 1 |
| Gressier, H; Malecot, E; Poignant, JC | 1 |
| Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A | 1 |
| Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P | 1 |
| Lahti, RA; McAllister, B; Wozniak, J | 1 |
| Bläsig, J; Herz, A; Papeschi, R | 2 |
| Collier, HO; McDonald-Gibson, WJ; Saeed, SA | 2 |
| Bass, P; Kennedy, JA; Wiley, JN | 1 |
| Hornykiewicz, O; Kuschinsky, K | 2 |
| Bläsig, J; Herz, A | 1 |
| Spoerlein, MT; VanderWende, C | 1 |
| Bose, AK; Brambilla, RJ; Cotzias, GC; Ginos, JZ; LoMonte, A | 1 |
| Lal, H; Puri, SK; Reddy, C | 1 |
| Ayhan, IH; Randrup, A | 1 |
| Kuschinsky, K; Sontag, KH; Wand, P | 1 |
| Lahti, RA; Losey, EG | 1 |
| Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H | 1 |
| Gessa, GL; Tagliamonte, A | 1 |
| Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H; Puri, SK | 1 |
| Kamioka, T; Kobayashi, S; Suzuki, Y; Tachikawa, R; Takagi, H | 1 |
| Moriya, R; Nagawa, Y; Nakajima, R; Saji, Y; Take, Y; Yui, T | 1 |
| Inoki, R; Iwatsubo, K; Shigenaga, Y | 1 |
| Dhasmana, KM; Dhawan, KN; Dixit, KS; Gupta, GP | 1 |
| Kühn, L; Pfeifer, S | 1 |
| Vedernikov, YP | 2 |
| Senault, B | 2 |
| Weissman, A | 1 |
| Paris, R; Sarsúnová, M | 1 |
| Laplace, JP; Ruckebusch, Y | 1 |
| Alhava, E; Mansner, R; Mattila, MJ | 1 |
| Haas, H; Jantos, W | 1 |
| Majlát, P | 1 |
| Burks, TF; Long, JP | 1 |
| Bhargava, HN | 1 |
| Langwiński, R; Malec, D | 1 |
| Barghon, R; Colboc, O; Costentin, J; Protais, P | 1 |
| Andrási, F; Horváth, K; Miglécz, E; Sineger, E; Székely, JI; Tarnawa, I | 1 |
| Ennis, C; Gaskin, M; Robbins, TW; Watson, BA | 1 |
| Nakamura, H; Shimizu, M; Yokoyama, Y | 1 |
| Carlson, KR; Seeger, TF | 1 |
| Clemens, JA; Shaar, CJ | 1 |
| Fratta, W; Grandison, L; Guidotti, A | 1 |
| Holtzman, SG; Teal, JJ | 1 |
| Bhargava, KP; Dixit, KS; Gupta, YK | 1 |
| Coombes, S; Pohl, RW; Revusky, S | 1 |
| Baggio, G; Ferrari, F | 1 |
| Zetler, G | 1 |
| Brake, SC; Spear, LP | 1 |
| Cubells, J; Gardner, EL; Hirschhorn, ID; Hittner, D; Makman, MH | 1 |
| Bergmann, F; Elam, R | 1 |
| Jaju, BP; Srivastava, YP | 1 |
| Sakakibara, S | 1 |
| Chou, CK; Guy, AW; Horita, A; Lai, H | 1 |
| Fujita, H; Shirasaki, K; Watanabe, H; Watanabe, K | 1 |
| Wassermann, K | 1 |
| Brann, MR; Ehrlich, YH; Ellis, J; Finnerty, M; Hacker, M; Lenox, RH | 1 |
| Feigenbaum, J; Klawans, H; Moon, B; Yanai, J | 1 |
| Invernizzi, R; Nowakowska, E; Samanin, R; Spampinato, U | 1 |
| Ogawa, GS | 1 |
| Brann, MR; Ehrlich, YH; Finnerty, M; Lenox, RH | 1 |
| Spaan, SJ; Westerink, BH | 1 |
| Crossman, AR; Slater, P | 1 |
| Slater, P | 1 |
| Fields, JZ; Lee, JM; Ritzmann, RF | 1 |
| Bogaert, MG; Lefebvre, RA; Willems, JL | 1 |
| Murakami, H; Segawa, T | 1 |
| Andreas, K; Engert, U; Fischer, HD | 1 |
| Wallnau, LB | 1 |
| McMillen, BA | 1 |
| Colpaert, FC; Janssen, PA; Niemegeers, CJ | 1 |
| Kulkarni, SK; Verma, A | 1 |
| Kang, JG; Kin, HS; Oh, KW | 1 |
| Antkiewicz-Michaluk, L; Michaluk, J; Romańska, I; Vetulani, J | 1 |
| Funada, M; Misawa, M; Nagase, H; Narita, M; Suzuki, T | 1 |
| Mamanpush, SM; Rashidy-Pour, A; Zarrindast, MR | 1 |
| Barraclough, CA; He, JR; Molnar, J | 1 |
| Dou, YL; Tang, F | 1 |
| Deschamps, SE; Druhan, JP; Stewart, J | 1 |
| Gifford, AN; Wang, RY | 1 |
| Jang, CG; Kim, HS; Park, WK | 1 |
| Knapp, CM; Kornetsky, C | 1 |
| Abrous, DN; Barrot, M; Le Moal, M; Maccari, S; Marinelli, M; Piazza, PV; Rougé-Pont, F; Simon, H | 1 |
| Capasso, A; Sorrentino, L | 1 |
| Argiolas, A; Iannucci, U; Melis, MR; Succu, S | 1 |
| el-Kadi, AO; Sharif, SI | 1 |
| Hu, WM; Kang, YM; Qiao, JT | 1 |
| Foss, JF; Goldberg, LI; Roizen, MF; Yuan, CS | 1 |
| Doğrul, A; Yeşilyurt, O | 1 |
| Farzin, D | 1 |
| Ho, IK; Jang, C; Loh, HH; Ma, T; Park, Y; Tanaka, S | 1 |
| Aston-Jones, G; Druhan, JP; Walters, CL | 2 |
| Oka, M; Yoshida, N; Yoshikawa, T | 1 |
| Jang, CG; Kim, HS; Lee, MK; Oh, KW; Oh, SK; Seong, YH; Woo, SH; Yun, JS | 1 |
| Ho, IK; Jang, CG; Lee, SY; Loh, HH; Ma, T; Park, Y | 1 |
| Kim, HS; Woo, SH | 1 |
| Cervo, L; De Deurwaerdère, P; Spampinato, U; Stinus, L | 1 |
| BEGLEY, RW; JONES, WR; WEAVER, LC | 1 |
| SCHIESER, DW | 1 |
| SCHUTE, JB | 1 |
| Gholami, A; Haeri-Rohani, A; Sahraei, H; Zarrindast, MR | 1 |
| NAHUNEK, K | 1 |
| de MORSIER, G; FELDMANN, H | 2 |
| DESRUELLES, M; FELLION, G | 1 |
| Liang, JH; Lu, Y; Ye, XF; Zhang, P | 1 |
| CHEYMOL, J; QUINQUAUD, A | 1 |
| MASON, MM | 1 |
| Fazli-Tabaei, S; Nasehi, M; Rezayof, A; Rostami, P; Zarrindast, MR | 1 |
| Fazli-Tabaei, S; Khalilzadeh, A; Malekmohammadi, N; Zarrindast, MR | 1 |
| Ito, S; Mori, T; Sawaguchi, T | 1 |
| Ardenghi, JV; De Souza, MM; Filho, VC; Kanegusuku, M; Monache, FD; Niero, R; Yunes, RA | 1 |
| IONESCO-MATIU, A; MONCIU, L; POPA, J | 1 |
| Ingram, SL; Kozell, LB; Meyer, PJ; Morgan, MM | 1 |
| Hosseini, SS; Rezayof, A; Zarrindast, MR | 1 |
| BARRERA, SE; FELDMAN, F; SUSSELMAN, S | 1 |
| Deisseroth, K; Doehner, J; Labouèbe, G; Lüscher, C; Mirzabekov, JJ; Tan, KR; Turiault, M; Tye, KM; Yvon, C | 1 |
| Gewirtz, JC; Radke, AK | 1 |
| Cui, C; Hu, L; Li, Y; Sun, L | 1 |
| Ghahremani, H; Kashanian, S; Paknejad, M; Shams, A | 1 |
| Costa, G; Morelli, M; Simola, N | 1 |
| Bobeck, EN; Morgan, MM; Schoo, SM | 1 |
| Carey, RJ; Carrera, MP; de Mello Bastos, JM; Leite Junior, JB; Samuels, RI | 1 |
| Carey, RJ; Carrera, MP; de Mello Bastos, JM; Leite, JB; Samuels, RI | 1 |
| Carey, RJ | 1 |
| Carey, RJ; Carrera, MP; Carvalho Crespo, LGS; Coimbra, NC; Leite Júnior, JB; Samuels, RI | 1 |
5 review(s) available for apomorphine and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Neurobiologic aspects of the morphine addictions].
Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dopamine; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Tolerance; Guinea Pigs; Humans; Mice; Models, Biological; Morphine; Morphine Dependence; Rats; Receptors, Drug; Serotonin; Substance Withdrawal Syndrome | 1974 |
[Theories and findings on the biosynthesis of aporphine and morphine alkaloids with special reference to dienone structures].
Topics: Apomorphine; Morphine; Papaverine | 1965 |
Periadolescence: age-dependent behavior and psychopharmacological responsivity in rats.
Topics: Age Factors; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Cocaine; Exploratory Behavior; Female; Haloperidol; Learning; Limbic System; Male; Morphine; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Receptors, Dopamine; Social Behavior | 1983 |
Drugs and memory: Evidence that drug effects can become associated with contextual cues by being paired post-trial with consolidation/re-consolidation. Mini review.
Topics: Animals; Apomorphine; Behavior, Animal; Central Nervous System Stimulants; Conditioning, Psychological; Cues; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Locomotion; Memory; Morphine; Motor Activity; Rats | 2020 |
258 other study(ies) available for apomorphine and morphine
| Article | Year |
|---|---|
Aporphines. 14 Dopaminergic and antinociceptive activity of aporphine derivatives. Synthesis of 10-hydroxyaporphines and 10-hydroxy-N-n-propylnoraporphine.
Topics: Analgesics; Animals; Aporphines; Dopamine; Humans; Male; Mice; Neural Pathways; Rats; Reaction Time; Stereotyped Behavior; Structure-Activity Relationship | 1976 |
Common stereospecificity of opioid and dopamine systems for N-butyrophenone prodine-like compounds.
Topics: Alphaprodine; Analgesia; Analgesics; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain; Dihydromorphine; Indicators and Reagents; Isomerism; Male; Mice; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu; Spiperone; Stereotyped Behavior; Structure-Activity Relationship | 1991 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Proceedings: The effects of buprenorphine, morphine and pentazocine on turning behaviour and stereotypy induced by apomorphine in the rat.
Topics: Animals; Apomorphine; Behavior; Cyclopropanes; Drug Interactions; Humans; Male; Morphinans; Morphine; Narcotic Antagonists; Pentazocine; Rats; Stereotyped Behavior; Time Factors | 1975 |
Catalepsy induced by morphine or haloperidol: effects of apomorphine and anticholinergic drugs.
Topics: Animals; Antipsychotic Agents; Apomorphine; Atropine; Benztropine; Catalepsy; Drug Interactions; Haloperidol; Humans; Male; Morphine; Rats; Scopolamine; Time Factors | 1976 |
Effects of drugs on the formation of homovanillic acid in the rat retina.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Rats; Retina | 1976 |
Sufentanil, a very potent and extremely safe intravenous morphine-like compound in mice, rats and dogs.
Topics: Analgesia; Analgesics, Opioid; Anilides; Animals; Antiemetics; Apomorphine; Dogs; Female; Fentanyl; Injections, Intravenous; Lethal Dose 50; Male; Meperidine; Mice; Mice, Inbred Strains; Morphine; Nalorphine; Piperidines; Pupil; Rats; Rats, Inbred Strains | 1976 |
Effect of morphine on brain apomorphine concentrations in the rat.
Topics: Animals; Apomorphine; Brain; Drug Interactions; Humans; Male; Morphine; Rats; Stereotyped Behavior; Time Factors | 1977 |
Suppression by GABAergic drugs of the locomotor stimulation induced by morphine, amphetamine, and apomorphine: evidence for both pre- and post-synaptic inhibition of catecholamine systems.
Topics: 4-Butyrolactone; Aminobutyrates; Aminooxyacetic Acid; Animals; Apomorphine; Brain; Clonidine; Corpus Striatum; Dextroamphetamine; Diencephalon; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Limbic System; Methyltyrosines; Mice; Morphine; Motor Activity; Naloxone; Norepinephrine; Reserpine; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1977 |
Effect of apomorphine on the antinociceptive activity of morphine.
Topics: Analgesics, Opioid; Animals; Apomorphine; Drug Synergism; Drug Tolerance; Female; Humans; Male; Mice; Morphine; Nalorphine; Rats; Rats, Inbred Strains; Reaction Time; Substance Withdrawal Syndrome; Time Factors | 1977 |
Indirect activation of the DA system as a possible mechanism for the stimulatory effects of narcotic analgesics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Analgesics, Opioid; Animals; Apomorphine; Catalepsy; Caudate Nucleus; Dextroamphetamine; Dopamine; Drug Interactions; Globus Pallidus; Humans; In Vitro Techniques; Injections; Mice; Morphine; Motor Activity; Olfactory Bulb; Rats; Stimulation, Chemical; Substantia Nigra | 1977 |
Morphine-induced changes in striatal dopamine mechanisms not evoked from the dopamine nerve terminals.
Topics: Animals; Apomorphine; Brain Chemistry; Brain Stem; Corpus Striatum; Dopamine; Humans; Male; Morphine; Nerve Endings; Potassium Chloride; Rats; Stereotyped Behavior; Tyrosine 3-Monooxygenase | 1978 |
Central neurotransmitter systems in the morphine suppression of jaw-opening reflex in rabbits: the dopaminergic system.
Topics: Animals; Apomorphine; Dopamine; Dopamine Antagonists; Haloperidol; Jaw; Morphine; Neurotransmitter Agents; Pain; Physostigmine; Pimozide; Rabbits; Reflex | 1979 |
Differential enhancement of locomotor activity by dopamine agonists following chronic morphine treatment.
Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Ergolines; Male; Morphine; Motor Activity; Rats; Time Factors | 1979 |
Prostaglandin synthesis inhibition and monoamine metabolites in the rat brain.
Topics: Animals; Apomorphine; Brain; Chlorpromazine; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Indomethacin; Male; Methoxyhydroxyphenylglycol; Morphine; Olfactory Bulb; Phenylacetates; Rats | 1979 |
Behavioral supersensitivity to apomorphine following chronic narcotic treatment in the guinea pig.
Topics: Animals; Apomorphine; Behavior, Animal; Guinea Pigs; Haloperidol; Humans; Male; Methadone; Morphine; Stereotyped Behavior; Time Factors | 1978 |
Is morphine-induced catalepsy related to activation of dopaminergic neurones?
Topics: Animals; Apomorphine; Catalepsy; Dopamine; Haloperidol; Humans; Male; Methyltyrosines; Morphine; Naloxone; Neurons; Rats; Stereotyped Behavior | 1978 |
Dual action of morphine and related drugs on compulsive gnawing of rats.
Topics: Animals; Apomorphine; Behavior, Animal; Compulsive Behavior; Female; Fenclonine; Humans; Meperidine; Methadone; Morphine; Naloxone; Rats; Serotonin; Stereotyped Behavior; Thalamic Nuclei | 1976 |
An analysis at synaptic level of the morphine action in striatum and N. accumbens: dopamine and acetylcholine interactions.
Topics: Acetylcholine; Animals; Apomorphine; Choline O-Acetyltransferase; Corpus Striatum; Cyclic AMP; Dextroamphetamine; Dopamine; Hypothalamus; Morphine; Norepinephrine; Olfactory Bulb; Rats; Synapses | 1975 |
Dopamine receptor sensitivity after repeated morphine administrations to rats.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Cyclic AMP; Dopamine; Homovanillic Acid; Humans; Male; Morphine; Rats; Receptors, Drug; Stereotyped Behavior; Stimulation, Chemical | 1975 |
Prostaglandins, cyclic AMP and the mechanism of opiate dependence.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Brain; Cattle; Codeine; Cyclic AMP; Humans; In Vitro Techniques; Male; Morphine; Morphine Dependence; Naloxone; Prostaglandins; Rats; Seminal Vesicles; Substance Withdrawal Syndrome; Substance-Related Disorders; Tissue Extracts | 1975 |
Genotype-dependent sensitivity to morphine: dopamine involvement in morphine-induced running in the mouse.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Genotype; Haloperidol; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Morphine; Motor Activity; Receptors, Adrenergic | 1976 |
On the mechanism of the decrease in cerebellar cyclic GMP content elicited by opiate receptor agonists.
Topics: Analgesics; Animals; Apomorphine; Cerebellum; Corpus Striatum; Cyclic GMP; Dextromoramide; Ethanolamines; Injections; Male; Morphine; Naltrexone; Narcotics; Pyridines; Rats; Reaction Time; Receptors, Opioid; Time Factors | 1977 |
Time-dependent disruptive effects of apomorphine and alpha-methyl-p-tyrosine on development of morphine tolerance.
Topics: Animals; Apomorphine; Ditiocarb; Drug Tolerance; Female; Haloperidol; Methyltyrosines; Morphine; Rats; Time Factors | 1977 |
The effects of opiate agonist and antagonist on serum prolactin in primates: possible role for endorphins in prolactin regulation.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Endorphins; Haloperidol; Haplorhini; Macaca; Male; Morphine; Naloxone; Prolactin; Receptors, Opioid | 1979 |
A comparison of narcotic analgesics with neuroleptics on behavioral measures of dopaminergic activity.
Topics: Aggression; Amphetamine; Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Dexetimide; Dextromoramide; Dogs; Dopamine; Drug Combinations; Haloperidol; Humans; Meperidine; Methadone; Mice; Morphine; Phenoperidine; Pimozide; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome; Tranquilizing Agents; Vomiting | 1975 |
Molecular mechanisms in the actions of morphine and viminol (R2) on rat striatum.
Topics: Animals; Apomorphine; Catecholamines; Corpus Striatum; Cyclic AMP; Dextroamphetamine; Dopamine; Ethanolamines; Haloperidol; Kinetics; Male; Morphine; Rats; Receptors, Drug; Tyrosine 3-Monooxygenase | 1975 |
Opiates, prolactin, and the dopamine receptor.
Topics: Apomorphine; Bromocriptine; Chlorpromazine; Cyproheptadine; Heroin Dependence; Humans; Kinetics; Levodopa; Methadone; Morphine; Prolactin; Receptors, Dopamine | 1978 |
Blockage of narcotic-induced dopamine receptor supersensitivity by cyclo(Leu-Gly).
Topics: Animals; Apomorphine; Body Temperature Regulation; Drug Tolerance; Humans; Male; Mice; Morphine; Motor Activity; Peptides, Cyclic; Piribedil; Receptors, Dopamine; Substance-Related Disorders | 1979 |
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; Mice; Morphinans; Morphine; Pain; Pentobarbital; Rats; Substance Withdrawal Syndrome; Thyrotropin-Releasing Hormone | 1977 |
Evidence for increased apomorphine-sensitive dopaminergic effects after acute treatment with morphine.
Topics: Animals; Apomorphine; Catalepsy; Dopamine; Drug Interactions; Humans; Male; Metergoline; Morphine; Motor Activity; Rats; Stereotyped Behavior; Time Factors | 1977 |
Effect of morphine on the accumulation of DOPA after decarboxylase inhibition in the rat.
Topics: 4-Butyrolactone; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Dihydroxyphenylalanine; DNA; Haloperidol; Male; Morphine; Naloxone; Rats; Receptors, Drug; Reserpine; Time Factors | 1979 |
gamma-Aminobutyric acid receptor function in rat anterior pituitary: evidence for control of prolactin release.
Topics: Animals; Apomorphine; Bicuculline; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Haloperidol; Male; Morphine; Muscimol; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Drug | 1979 |
Dopaminergic and non-dopaminergic circling activity of mice.
Topics: Amphetamine; Animals; Apomorphine; Atropine; Dopamine; Dopamine Antagonists; Functional Laterality; Male; Mice; Morphine; Motor Activity; Pentylenetetrazole | 1979 |
Anti-nociceptive effect of morphine, opioid analgesics and haloperidol injected into the caudate nucleus of the rat.
Topics: Analgesics; Animals; Apomorphine; Caudate Nucleus; Female; Haloperidol; Injections; Male; Morphine; Naloxone; Narcotics; Rats | 1979 |
Gastric relaxation by morphine, apomorphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Benzimidazoles; Dogs; Domperidone; Fentanyl; Haloperidol; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Piperidines; Stomach; Vomiting | 1979 |
Morphine-induced striatal dopamine efflux depends on the activity of nigrostriatal dopamine neurones.
Topics: Action Potentials; Animals; Apomorphine; Corpus Striatum; Dopamine; Haloperidol; Male; Morphine; Neurons; Rats; Substantia Nigra | 1979 |
Enhanced prolactin inhibition following chronic treatment with haloperidol and morphine.
Topics: Animals; Apomorphine; Dopamine; Haloperidol; Humans; Hypothalamus; Male; Morphine; Neural Pathways; Prolactin; Rats; Substance Withdrawal Syndrome; Thalamus | 1977 |
Influence of morphine dependence and withdrawal on circling behaviour in rats with unilateral nigral lesions [proceedings].
Topics: Animals; Apomorphine; Behavior, Animal; Humans; Male; Morphine; Morphine Dependence; Rats; Rotation; Substance Withdrawal Syndrome; Substantia Nigra | 1977 |
Changes in sensitivity to operant effects of dopaminergic and cholinergic agents following morphine withdrawal in rats.
Topics: Animals; Apomorphine; Conditioning, Operant; Dopamine; Female; Haloperidol; Humans; Morphine; Pilocarpine; Rats; Reinforcement Schedule; Scopolamine; Substance Withdrawal Syndrome; Time Factors | 1977 |
Neuroanatomical focus for morphine and enkephalin-induced hypermotility.
Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Enkephalins; Haloperidol; Humans; Hyperkinesis; Injections; Injections, Intraperitoneal; Male; Morphine; Naloxone; Olfactory Bulb; Oligopeptides; Rats; Stimulation, Chemical; Time Factors | 1977 |
Changes in dopamine receptors in mouse striatum following morphine treatments.
Topics: Animals; Apomorphine; Benzimidazoles; Corpus Striatum; Homovanillic Acid; Humans; Male; Mice; Morphine; Piperidines; Receptors, Dopamine; Stereotyped Behavior; Time Factors | 1979 |
Time course of dopaminergic hypersensitivity following chronic narcotic treatment.
Topics: Animals; Apomorphine; Dopamine; Guinea Pigs; Humans; Male; Methadone; Morphine; Narcotics; Stereotyped Behavior; Time Factors | 1979 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Haloperidol; Humans; Isoxazoles; Male; Methyltyrosines; Morphine; Motor Activity; Muscimol; Picrotoxin; Rats; Reserpine | 1979 |
[Neurophoarmacologic profile of an aminotetraline derivative].
Topics: Amphetamine; Analgesics; Animals; Apomorphine; Central Nervous System; Drug Interactions; Hexobarbital; Mice; Morphine; Motor Activity; Muscle Tonus; Naphthols; Nervous System; Pentylenetetrazole; Piperazines; Rats; Reserpine; Strychnine | 1977 |
Antagonism of morphine-induced central stimulation in mice by small doses of catecholamine-receptor agonists.
Topics: Animals; Apomorphine; Brain; Clonidine; Dopamine; Levodopa; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Norepinephrine; Parasympathomimetics | 1978 |
Effects of opiates on the discriminative stimulus properties of dopamine agonists.
Topics: Amphetamine; Animals; Apomorphine; Discrimination, Psychological; Dopamine; Haloperidol; Male; Morphine; Naltrexone; Narcotics; Pentazocine; Rats; Time Factors | 1978 |
Effects of morphine on the serum prolactin levels of morphine-tolerant and nontolerant male rats and of the in vitro release of pituitary prolactin.
Topics: Animals; Apomorphine; Diphenhydramine; Dopamine; Drug Tolerance; Haloperidol; In Vitro Techniques; Male; Morphine; Naloxone; Pituitary Gland, Anterior; Prolactin; Rats | 1978 |
On the regulation of gamma-aminobutyric acid neurons in caudatus, pallidus and nigra: effects of opioids and dopamine agonists.
Topics: Animals; Apomorphine; Brain; Caudate Nucleus; Corpus Striatum; Decerebrate State; Dopamine; Endorphins; gamma-Aminobutyric Acid; Globus Pallidus; Male; Morphine; Naltrexone; Narcotics; Neurons; Rats; Substantia Nigra | 1979 |
Alterations in the effects of dopamine agonists and antagonists on general activity in rats following chronic morphine treatment.
Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Haloperidol; Male; Morphine; Motor Activity; Pimozide; Rats; Time Factors | 1976 |
Dopamine and the depressant action of morphine on stimulated guinea-pig ileum.
Topics: Animals; Apomorphine; Dopamine; Electric Stimulation; Female; Guinea Pigs; Hydroxydopamines; Ileum; Male; Morphine; Muscle Contraction; Naloxone; Phentolamine; Propranolol | 1977 |
Specific action of narcotics on reflex activation of rat alpha-motoneurones.
Topics: Action Potentials; Animals; Apomorphine; Dextrorphan; Electric Stimulation; Levorphanol; Male; Morphine; Motor Neurons; Naloxone; Narcotics; Rats; Reflex; Spinal Cord | 1977 |
Vasodilatation produced by apomorphine in the hindleg of the dog.
Topics: Animals; Apomorphine; Blood Circulation; Denervation; Dogs; Dopamine; Electric Stimulation; Female; Femoral Artery; Haloperidol; Male; Morphine; Norepinephrine; Phenoxybenzamine; Pyrilamine; Receptors, Dopamine; Vasodilator Agents | 1977 |
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol | 1977 |
Centrally mediated intestinal stimulation by morphine.
Topics: Action Potentials; Animals; Apomorphine; Behavior, Animal; Cats; Epinephrine; Female; Injections, Intraperitoneal; Injections, Intraventricular; Intestine, Small; Male; Morphine; Stimulation, Chemical; Time Factors; Vomiting | 1977 |
Behavioral correlates of dopaminergic function in the nucleus accumbens.
Topics: Animals; Apomorphine; Dextroamphetamine; Dopamine; Ergonovine; Injections; Mice; Morphine; Motor Activity; Olfactory Bulb; Rats; Reinforcement, Psychology; Reward; Stimulation, Chemical | 1977 |
Effects of morphine and haloperidol on the electrical activity of rat nigrostriatal neurons.
Topics: Action Potentials; Animals; Apomorphine; Caudate Nucleus; Corpus Striatum; Haloperidol; Injections; Injections, Intravenous; Levodopa; Male; Morphine; Narcotic Antagonists; Neurons; Rats; Substantia Nigra; Time Factors | 1977 |
Intestinal stimulant response after intraventricular morphine in the conscious cat.
Topics: Action Potentials; Animals; Apomorphine; Cats; Epinephrine; Female; Injections, Intraventricular; Intestine, Small; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Stimulation, Chemical | 1977 |
Intestinal myoelectric activity after activation of central emetic mechanism.
Topics: Action Potentials; Animals; Apomorphine; Cats; Epinephrine; Female; Injections, Intraperitoneal; Injections, Intraventricular; Intestine, Small; Ketamine; Male; Morphine; Naloxone; Phentolamine; Vomiting | 1977 |
Behavioral effects of 5, 7-dihydroxytryptamine lesions of ascending 5-hydroxytryptamine pathways.
Topics: Afferent Pathways; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Humans; Male; Mesencephalon; Morphine; Motor Activity; Neurons; Norepinephrine; Pain; Protriptyline; Rats; Serotonin; Stereotyped Behavior | 1976 |
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.
Topics: Animals; Apomorphine; Cyclazocine; Cyclopropanes; Dextropropoxyphene; Dogs; Ethylketocyclazocine; Humans; Morphinans; Morphine; Morphine Dependence; Nalorphine; Naltrexone; Phenazocine; Spinal Cord | 1976 |
Acidic dopamine metabolites in cortical areas of the rat brain: localization and effects of drug.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Cerebral Cortex; Clozapine; Corpus Striatum; Haloperidol; Homovanillic Acid; Male; Morphine; Olfactory Bulb; Oxotremorine; Phenylacetates; Probenecid; Rats; Sulpiride; Thioridazine | 1976 |
Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone.
Topics: Aggression; Animals; Apomorphine; Drug Interactions; Humans; Male; Morphine; Naloxone; Parasympatholytics; Pilocarpine; Rats; Time Factors; Tranquilizing Agents | 1976 |
Enhancement of morphine-withdrawal and apomorphine-induced aggression by clonidine.
Topics: Aggression; Animals; Apomorphine; Clonidine; Humans; Male; Morphine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome; Vocalization, Animal | 1976 |
Comparison of effects of drugs on dopamine metabolism in the substantia nigra and the corpus striatum of rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Chloral Hydrate; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Morphine; Oxotremorine; Pargyline; Phenylacetates; Probenecid; Promethazine; Rats; Receptors, Dopamine; Substantia Nigra | 1976 |
Derivatives of apomorphine and of other N-substituted norapomorphines.
Topics: Animals; Apomorphine; Dogs; Dose-Response Relationship, Drug; Drug Stability; Emetics; Lethal Dose 50; Mice; Morphine; Reaction Time; Structure-Activity Relationship | 1976 |
Changes in the myoelectric activity of the small intestine associated with drug-induced emesis in the conscious cat.
Topics: Animals; Apomorphine; Brain; Cats; Drug Interactions; Electromyography; Emetics; Epinephrine; Female; Intestine, Small; Male; Morphine; Receptors, Drug | 1976 |
Dose-response shifts in the behavioural effects of dopamine agonists and antagonists following chronic morphine treatment.
Topics: Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Dopamine; Dopamine Antagonists; Drug Tolerance; Haloperidol; Humans; Male; Morphine; Motor Activity; Pimozide; Rats; Stereotyped Behavior; Time Factors | 1976 |
Dopaminergic sites involved in morphine withdrawal hypothermia.
Topics: Animals; Apomorphine; Body Temperature; Dopamine; Drug Implants; Humans; Hypothalamus; Injections; Male; Morphine; Naloxone; Pimozide; Rats; Receptors, Dopamine; Substance Withdrawal Syndrome | 1976 |
Screening hallucinogenic drugs: systematic study of three behavioral tests.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Arousal; Behavior, Animal; Chlorpromazine; Diazepam; Drug Evaluation, Preclinical; Grooming; Hallucinogens; Head; Male; Mice; Morphine; Motor Activity; Movement Disorders; Pentobarbital; Rats; Reinforcement Schedule; Reinforcement, Psychology; Research Design | 1975 |
Hyperthermic and hypothermic effects of morphine in mice: interactions with apomorphine and pilocarpine and changes in sensitivity after caudate nucleus lesions.
Topics: Animals; Apomorphine; Body Temperature; Caudate Nucleus; Depression, Chemical; Drug Interactions; Female; Mice; Morphine; Pilocarpine; Stimulation, Chemical; Time Factors | 1975 |
Blockade by narcotic drugs of naloxone-precipitated jumping in morphine-dependent mice.
Topics: Administration, Oral; Animals; Apomorphine; Behavior, Animal; Codeine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Injections, Intraperitoneal; Male; Meperidine; Methadone; Mice; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotics; Pentazocine; Substance Withdrawal Syndrome | 1975 |
Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats.
Topics: Animals; Apomorphine; Dopamine; Humans; Hypothermia; Male; Morphine; Naloxone; Pimozide; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1975 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors | 1975 |
Studies on dopamine kinetics in rat brain tissue under the influence of morphine.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Imipramine; In Vitro Techniques; Kinetics; Morphine; Morphine Dependence; Naloxone; Potassium; Rats; Sensory Receptor Cells; Stereotyped Behavior | 1975 |
The effect of dopaminergic stimulation and blockade on the nociceptive and antinociceptive responses of mice.
Topics: Analgesics; Animals; Apomorphine; Depression, Chemical; Dopamine; Haloperidol; Levodopa; Male; Mice; Morphine; Naloxone; Pain; Pimozide; Reaction Time; Receptors, Drug; Stimulation, Chemical | 1975 |
Effects of morphine on serum growth hormone, cortisol, prolactin and thyroid stimulating hormone in man.
Topics: Apomorphine; Female; Growth Hormone; Humans; Hydrocortisone; Morphine; Prolactin; Stimulation, Chemical; Thyrotropin; Time Factors | 1975 |
Dopaminergic and cholinergic influences on morphine self-administration in rats.
Topics: Animals; Apomorphine; Dopamine; Female; Haloperidol; Morphine; Parasympathetic Nervous System; Pilocarpine; Rats; Scopolamine | 1975 |
A new central direct dopaminergic stimulant: 1-(Coumaran-5-yl methyl)-4-(2-thiazolyl) piperazine hydrochloride (S 3608).
Topics: Animals; Apomorphine; Behavior, Animal; Benzofurans; Catatonia; Corpus Striatum; Drug Interactions; Ergolines; Humans; Hydroxydopamines; Male; Morphine; Piperazines; Rats; Stereotyped Behavior; Substantia Nigra; Thiazoles; Yohimbine | 1975 |
Effect of morphine antagonists on drug-induced hypothermia in mice and rats.
Topics: Animals; Antidepressive Agents; Apomorphine; Body Temperature; Cyclazocine; Desipramine; Dextroamphetamine; Diprenorphine; Drug Evaluation, Preclinical; Female; Male; Methyltyrosines; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxotremorine; Rats; Reserpine | 1976 |
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: site of action in the brain.
Topics: Analgesics; Animals; Apomorphine; Benzeneacetamides; Brain; Injections, Intraventricular; Male; Microinjections; Morphine; Naloxone; Narcotic Antagonists; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Yawning | 1992 |
Place conditioning in a three- or four-choice apparatus: role of stimulus novelty in drug-induced place conditioning.
Topics: Animals; Apomorphine; Arousal; Association Learning; Avoidance Learning; Chlorides; Choice Behavior; Conditioning, Classical; Dextroamphetamine; Dose-Response Relationship, Drug; Lithium; Lithium Chloride; Male; Morphine; Motivation; Motor Activity; Nicotine; Orientation; Psychotropic Drugs; Rats; Rats, Inbred Strains; Social Environment | 1992 |
Activation of the zinc finger encoding gene krox-20 in adult rat brain: comparison with zif268.
Topics: Animals; Apomorphine; Benzazepines; Brain; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 2; Electroshock; Haloperidol; Immediate-Early Proteins; Male; Morphine; Naltrexone; Nucleic Acid Hybridization; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Substance Withdrawal Syndrome; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1992 |
Oxytocin stimulation of penile erection. Pharmacology, site, and mechanism of action.
Topics: Angiotensin Receptor Antagonists; Animals; Apomorphine; Calcium; GTP-Binding Proteins; Male; Morphine; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Receptors, Angiotensin; Receptors, Oxytocin; Second Messenger Systems | 1992 |
The actions of fentanyl to inhibit drug-induced emesis.
Topics: Animals; Antiemetics; Apomorphine; Autoradiography; Brain Stem; Cisplatin; Copper; Copper Sulfate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Fentanyl; Ferrets; Male; Morphine; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Vomiting | 1991 |
Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Cocaine; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Dopamine Agents; Drug Synergism; Ergolines; Generalization, Psychological; Haloperidol; Lead; Male; Morphine; N-Methylaspartate; Pentobarbital; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu | 1991 |
Dopamine receptor subtypes and formalin test analgesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analgesia; Animals; Apomorphine; Benzazepines; Dextroamphetamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Ergolines; Flupenthixol; Formaldehyde; Male; Morphine; Pain; Pimozide; Quinpirole; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1991 |
Reinforcing properties of morphine chronically used in aversive life conditions: place-preference paradigm, long-term changes in behavioral reactivity.
Topics: Animals; Apomorphine; Behavior, Animal; Choice Behavior; Environment; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Restraint, Physical; Reward; Stress, Physiological; Time Factors | 1991 |
Dopaminergic involvement in the mediation of morphine effects on vocalization and movement reactivity in the rat.
Topics: Animals; Apomorphine; Dopamine; Drug Combinations; Haloperidol; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Vocalization, Animal | 1991 |
Dopamine D2 receptors and spinal cord excitation in mice.
Topics: Animals; Apomorphine; Benzazepines; Dopamine Antagonists; Haloperidol; Injections, Spinal; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Receptors, Dopamine; Receptors, Dopamine D2; Reflex; Spinal Cord; Sulpiride | 1990 |
Role of opiates in striatal D-1 dopamine receptor supersensitivity induced by chronic L-dopa treatment.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Drug Interactions; Hydroxydopamines; Levodopa; Male; Morphine; Naltrexone; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Opioid | 1990 |
[A new system for the measurement and analysis of motor activity in mice: effect of several central stimulants].
Topics: Animals; Apomorphine; Behavioral Sciences; Caffeine; Cocaine; Dose-Response Relationship, Drug; Male; Methamphetamine; Mice; Morphine; Motor Activity | 1990 |
Ontogeny of the endorphinergic and dopaminergic modulation on the immobility reflex elicited by clamping in rats.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Endorphins; Female; Haloperidol; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Reflex | 1990 |
Dopamine receptor subsensitivity in the substantia nigra after chronic morphine treatment in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Autoradiography; Behavior, Animal; Chromatography, High Pressure Liquid; Dopamine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Substantia Nigra | 1988 |
Role of dopamine receptors in gastrointestinal motility.
Topics: Animals; Apomorphine; Benzazepines; Domperidone; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Gastrointestinal Transit; Haloperidol; In Vitro Techniques; Male; Morphine; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1989 |
Independent effects of morphine and apomorphine on stereotyped gnawing in the hamster.
Topics: Animals; Apomorphine; Cricetinae; Dose-Response Relationship, Drug; Female; Mesocricetus; Morphine; Naloxone; Stereotyped Behavior; Time Factors | 1989 |
Effect of chronic treatment with morphine on the binding of 3H-N-n-propylnorapomorphine to striatal membranes of rats: influence of prolyl-leucyl-glycinamide.
Topics: Animals; Antiparkinson Agents; Apomorphine; beta-Endorphin; Corpus Striatum; Drug Tolerance; Endorphins; Kinetics; Male; Membranes; Morphine; MSH Release-Inhibiting Hormone; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1985 |
Does individually different sensitivity to dopaminergic stimulation determine the degree of tolerance and dependence to opioids?
Topics: Animals; Apomorphine; Dopamine Agents; Drug Tolerance; Electromyography; Morphine; Motor Activity; Narcotics; Opioid-Related Disorders; Rats; Stereotyped Behavior | 1988 |
A study of central neurotransmitter mechanisms in morphine-induced 'Straub reaction' in mice: role of central dopamine receptors.
Topics: Animals; Apomorphine; Dopamine Agents; Dose-Response Relationship, Drug; Female; Male; Mice; Morphine; Neurotransmitter Agents; Receptors, Dopamine; Synaptic Transmission; Tail | 1988 |
Opposing effect of apomorphine on antinociceptive activity of morphine: a dose-dependent phenomenon.
Topics: Animals; Apomorphine; Cerebral Ventricles; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Injections, Intraventricular; Male; Morphine; Nociceptors; Pain Measurement; Rats; Receptors, Dopamine; Synapses | 1989 |
Opioid influence on some aspects of stereotyped behavior induced by repeated amphetamine treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; beta-Endorphin; Corpus Striatum; Dopamine; Male; Morphine; Naloxone; Narcotics; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reference Values; Stereotyped Behavior | 1988 |
The effects of morphine and morphine-related compounds on the rate of afferent discharges from the pulmonary receptors in bullfrog.
Topics: Animals; Apomorphine; Capsaicin; Dextromethorphan; In Vitro Techniques; Levallorphan; Lung; Morphine; Morphine Derivatives; Naloxone; Neurons, Afferent; Pentazocine; Rana catesbeiana; Receptors, Opioid | 1985 |
Increased sensitivity to dopamine agonists following a single dose of morphine or levorphanol in mice.
Topics: Animals; Apomorphine; Brain; Brain Stem; Cerebral Cortex; Chlorides; Corpus Striatum; Dextrorphan; Drug Synergism; Hippocampus; Levorphanol; Lithium; Lithium Chloride; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotics; Receptors, Dopamine; Spiperone | 1985 |
The use of cyclic AMP efflux studies in attempts to determine the effects of morphine on cyclic AMP formation in striatal slices.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Benzazepines; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; In Vitro Techniques; Morphine; Naloxone; Rats | 1986 |
Relative ontogeny of opioid and catecholaminergic regulation of thyrotropin secretion in the rat.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Body Temperature; Catecholamines; Clonidine; Cold Temperature; Corticosterone; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1988 |
Stability of morphine solutions in plastic syringes determined by reversed-phase ion-pair liquid chromatography.
Topics: Apomorphine; Chromatography, Ion Exchange; Codeine; Drug Stability; Light; Morphine; Plastics; Spectrophotometry, Ultraviolet; Syringes; Temperature | 1988 |
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea Pigs; Haloperidol; Lisuride; Morphine; Myoclonus; Naloxone; Scopolamine; Tremorine | 1986 |
Modification of the development of acute opiate tolerance by increased dopamine receptor sensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Drug Interactions; Drug Tolerance; Levorphanol; Lithium; Male; Mice; Morphine; Naloxone; Narcotics; Opioid-Related Disorders; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1987 |
Further evidence that a single dose of an opiate can increase dopamine receptor sensitivity in mice.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Haloperidol; Levorphanol; Male; Mice; Morphine; Narcotics; Receptors, Dopamine | 1987 |
Chronically administered morphine increases dopamine receptor sensitivity in mice.
Topics: Analgesia; Animals; Apomorphine; Behavior, Animal; Binding Sites; Brain; Drug Implants; Drug Tolerance; Hypothermia; Lithium; Male; Mice; Morphine; Naloxone; Receptors, Dopamine; Spiperone; Substance Withdrawal Syndrome | 1986 |
Effects of apomorphine on morphine analgesia during the state of dopaminergic supersensitivity after chronic treatment with haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Haloperidol; Male; Morphine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Time Factors | 1986 |
Effects of nitrogen and helium at pressure on drug-induced stereotypy and locomotion in mice.
Topics: Air Pressure; Animals; Apomorphine; Brain Chemistry; Dextroamphetamine; Dose-Response Relationship, Drug; Helium; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Nitrogen; Stereotyped Behavior | 1986 |
Evidence for a permanent decline in tuberoinfundibular dopaminergic neuronal function after chronic estrogen treatment is terminated in Fischer 344 rats.
Topics: Animals; Apomorphine; Dopamine; Estradiol; Female; Haloperidol; Luteinizing Hormone; Median Eminence; Morphine; Neurons; Nomifensine; Ovariectomy; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred F344 | 1986 |
Interactions of morphine with apomorphine: behavioural and biochemical studies.
Topics: Animals; Apomorphine; Brain Chemistry; Dopamine; Lisuride; Male; Morphine; Pargyline; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1986 |
[Effect on morphine hyperthermia of dopaminergic agents].
Topics: Animals; Apomorphine; Body Temperature; Bromocriptine; Drug Interactions; Fever; Haloperidol; Male; Methotrimeprazine; Morphine; Naloxone; Rats; Rats, Inbred Strains; Rectum; Time Factors | 1985 |
Effect of cyclic nucleotides on apomorphine stereotypy and chlorpromazine catalepsy in mice.
Topics: Animals; Apomorphine; Catalepsy; Chlorpromazine; Male; Mice; Mice, Inbred Strains; Morphine; Nucleotides, Cyclic; Stereotyped Behavior; Structure-Activity Relationship | 1985 |
Drug discrimination procedures: roles of relative stimulus control in two-drug cases.
Topics: Animals; Apomorphine; Cocaine; Columbidae; Discrimination Learning; Generalization, Psychological; Lysergic Acid Diethylamide; Morphine; Pentobarbital | 1985 |
Persistence of low hypothalamic dopaminergic activity after removal of chronic estrogen treatment.
Topics: Animals; Apomorphine; DNA; Dopamine; Estrogens; Female; Growth Hormone; Haloperidol; Hypothalamus; Morphine; Ovariectomy; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred F344; Receptors, Dopamine | 1986 |
Influence of peripheral and central administration of apomorphine and morphine on intragastric pressure in the dog.
Topics: Animals; Apomorphine; Brain; Chemoreceptor Cells; Dogs; Domperidone; Female; Injections, Intravenous; Injections, Intraventricular; Morphine; Naloxone; Pressure; Stomach; Vomiting | 1985 |
Modification of antinociceptive action of morphine by dopamine agonist and antagonist in mice.
Topics: Animals; Apomorphine; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Male; Mice; Mice, Inbred Strains; Morphine; Receptors, Dopamine | 1985 |
Evaluation of immunoassay methods for detection, in urine, of drugs subject to abuse.
Topics: Amphetamine; Apomorphine; Barbiturates; Chromatography, Thin Layer; Cocaine; Codeine; Cross Reactions; Cyclazocine; Dextromethorphan; Dextropropoxyphene; Evaluation Studies as Topic; Hemagglutination Inhibition Tests; Heroin; Humans; Hydromorphone; Levorphanol; Methadone; Methods; Microchemistry; Morphine; Nalorphine; Radioimmunoassay; Spectrometry, Fluorescence; Substance-Related Disorders; Time Factors; Tritium | 1974 |
Effect of morphine and chlorpromazine on apomorphine-induced stereotyped behavior.
Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Drug Synergism; Humans; Male; Morphine; Rats; Receptors, Drug; Stereotyped Behavior | 1974 |
Comparative effects of apomorphine, piribedil and other neurotropic agents on central analgesic-induced catatonia in the rat.
Topics: Amantadine; Analgesics, Opioid; Animals; Antiparkinson Agents; Apomorphine; Atropine; Benserazide; Benzyl Compounds; Catatonia; Dextroamphetamine; Dextromoramide; Dihydroxyphenylalanine; Dioxoles; Dose-Response Relationship, Drug; Humans; Male; Morphine; Piperazines; Pyrimidines; Rats; Time Factors; Trihexyphenidyl | 1974 |
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus | 1974 |
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine | 1971 |
Apomorphine antagonism of the elevation of homovanillic acid induced by antipsychotic drugs.
Topics: Amantadine; Animals; Apomorphine; Brain; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Haloperidol; Homovanillic Acid; Mice; Morphine; Phenylacetates; Receptors, Adrenergic; Structure-Activity Relationship; Synaptic Transmission; Thiothixene; Tranquilizing Agents; Trifluoperazine | 1972 |
[Significance of catecholamines for the manifestation of morphine withdrawal in the rat].
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Catecholamines; Desipramine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Norepinephrine; Rats; Substance Withdrawal Syndrome | 1974 |
Apomorphine and morphine stimulate prostaglandin biosynthesis.
Topics: Animals; Apomorphine; Aspirin; Cattle; Chlorpromazine; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Male; Mixed Function Oxygenases; Morphine; Prostaglandins; Seminal Vesicles; Sodium Salicylate; Stimulation, Chemical; Tritium | 1974 |
Proceedings: Morphine and apomorphine stimulate prostaglandin production by rabbit brain homogenate.
Topics: Animals; Apomorphine; Brain; Male; Morphine; Prostaglandins; Rabbits; Stimulation, Chemical | 1974 |
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Eye Movements; Humans; Levallorphan; Male; Methyltyrosines; Morphine; Morphine Dependence; Motor Activity; Nasal Mucosa; Norepinephrine; Piperazines; Rats; Serotonin; Substance Withdrawal Syndrome | 1974 |
Measurement of fecal output in rats.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Atropine; Chlorpromazine; Codeine; Cyclazocine; Digestive System; Feces; Housing, Animal; Levallorphan; Magnesium Sulfate; Male; Mecamylamine; Meperidine; Methotrimeprazine; Methylamines; Mineral Oil; Morphine; Muscle, Smooth; Opium; Papaverine; Pentazocine; Rats | 1972 |
Effects of morphine on striatal dopamine metabolism: possible mechanism of its opposite effect on locomotor activity in rats and mice.
Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Catechols; Caudate Nucleus; Chlorpromazine; Clonidine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Fluorometry; Homovanillic Acid; Humans; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Rats; Serine; Species Specificity; Stereotaxic Techniques; Thiocarbamates | 1974 |
Role of dopaminergic receptors in morphine analgesia and tolerance.
Topics: Amantadine; Analgesia; Animals; Apomorphine; Dibenzothiazepines; Dopamine; Drug Synergism; Drug Tolerance; Male; Mice; Mice, Inbred Strains; Morphine; Perphenazine; Phenoxybenzamine; Receptors, Adrenergic; Serine; Spiro Compounds | 1973 |
Synthesis of tritium- and deuterium-labeled apomorphine.
Topics: Apomorphine; Catechols; Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methods; Morphine; Tritium | 1973 |
Blockade of central dopaminergic receptors of morphine: effect of haloperidol, apomorphine or benztropine.
Topics: Animals; Antiparkinson Agents; Apomorphine; Benztropine; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Haloperidol; Humans; Kinetics; Male; Morphine; Rats; Receptors, Drug; Stereotyped Behavior; Tropanes | 1973 |
Inhibitory effects of amphetamine, L-DOPA and apomorphine on morphine-induced behavioural excitation of rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Dextroamphetamine; Dihydroxyphenylalanine; Grooming; Morphine; Motor Activity; Rats; Stimulation, Chemical; Time Factors | 1973 |
Morphine-induced muscular rigidity in rats.
Topics: Animals; Apomorphine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Electromyography; Male; Morphine; Muscle Rigidity; Naloxone; Narcotic Antagonists; Rats; Time Factors | 1973 |
Antagonism of the effects of chlorpromazine and morphine on dopamine metabolism by GABA.
Topics: Acetates; Aminobutyrates; Animals; Apomorphine; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxylamines; Male; Methyltyrosines; Morphine; Rats | 1974 |
Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol.
Topics: Administration, Oral; Aggression; Animals; Apomorphine; Behavior, Animal; Body Temperature; Dopamine; Haloperidol; Humans; Injections, Intraperitoneal; Morphine; Movement; Rats; Receptors, Drug; Time Factors | 1974 |
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase | 1974 |
Effect of apomorphine and nigrostriatal lesions on aggression and striatal dopamine turnover during morphine withdrawal: evidence for dopaminergic supersensitivity in protracted abstinence.
Topics: Aggression; Animals; Apomorphine; Corpus Striatum; Dopamine; Humans; Male; Morphine; Rats; Substance Withdrawal Syndrome; Substantia Nigra; Time Factors | 1974 |
[Pharmacological studies of oxazolazepam, a new psychotropic agent. I. Actions on the central nervous system, especially on the behavioral aspect].
Topics: Adaptation, Biological; Analgesics; Anesthesia; Animals; Anticonvulsants; Apomorphine; Avoidance Learning; Azepines; Behavior, Animal; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Cricetinae; Diazepam; Dogs; Drug Synergism; Drug Tolerance; Electric Stimulation; Female; Guinea Pigs; Haplorhini; Male; Mice; Morphine; Oxazoles; Rats; Seizures; Thiopental; Tranquilizing Agents; Tremorine | 1970 |
Pharmacological studies on new potent central depressants, 8-chloro-6-phenyl-4H-s-triazolo [4,3a][1,4] benzodiazepine (D-40tA) and its 1-methyl analogue (D-65MT).
Topics: Administration, Oral; Aggression; Animals; Anticonvulsants; Antiemetics; Apomorphine; Avoidance Learning; Azepines; Behavior, Animal; Benzazepines; Cats; Central Nervous System; Chlordiazepoxide; Chlorprothixene; Diazepam; Discrimination Learning; Dogs; Drug Synergism; Female; Haplorhini; Hexobarbital; Humans; Injections, Intraperitoneal; Lethal Dose 50; Male; Mescaline; Methamphetamine; Mice; Morphine; Motor Activity; Muscle Relaxants, Central; Reserpine; Sleep; Tetrabenazine; Triazoles | 1971 |
Morphine catalepsy in the rat: relation to striatal dopamine metabolism.
Topics: Animals; Apomorphine; Brain Chemistry; Catalepsy; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Humans; Male; Methadone; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains | 1972 |
[Pharmacological studies of a new minor tranquilizer, dipotassium chlorazepate (7-chloro-1,3-dihydro-2-oxo-5-phenyl-1H-1, 4-benzodiazepine 3-carboxylic acid monopotassium salt monopotassium hydroxide). 1. Central action].
Topics: Animals; Anticonvulsants; Apomorphine; Bemegride; Benzazepines; Central Nervous System; Cerebral Cortex; Diazepam; Dogs; Electroencephalography; Evoked Potentials; Hexobarbital; Hypothalamus; Limbic System; Male; Mice; Morphine; Nicotine; Pentylenetetrazole; Rats; Strychnine; Tranquilizing Agents; Tremorine | 1972 |
Blockade of depressor response of dopamine.
Topics: Animals; Apomorphine; Blood Pressure; Cats; Chlorpromazine; Codeine; Dopamine; Female; Male; Meperidine; Morphine; Phenothiazines; Phenoxybenzamine; Yohimbine | 1969 |
Interaction of amphetamine, apomorphine, disulfiram with morphine and the role played by catecholamines in morphine analgesic action.
Topics: Amphetamine; Animals; Apomorphine; Disulfiram; Drug Tolerance; Female; Morphine; Rats | 1969 |
The influence of single and chronic morphine administration on some central effects of amphetamine and apomorphine.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Drug Tolerance; Female; Mice; Morphine; Rats; Time Factors | 1970 |
[Intraspecific aggressive behavior induced by apomorphine in the rat].
Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine | 1970 |
Cliff jumping in rats after intravenous treatment with apomorphine.
Topics: Amphetamine; Animals; Apomorphine; Basal Ganglia; Behavior, Animal; Desipramine; Dihydroxyphenylalanine; Male; Morphine; Rats; Receptors, Adrenergic; Tetrabenazine | 1971 |
[Thin layer chromatographic separation of opium alkaloids and various products of partial synthetic modification].
Topics: Apomorphine; Chromatography, Thin Layer; Codeine; Methods; Morphine; Noscapine; Opium; Papaverine; Thebaine | 1967 |
[Pharmacologic changes in feeding behavior: food intake and rumination in sheep].
Topics: Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Cerebral Cortex; Chlorpromazine; Digestion; Digitalis Glycosides; Eating; Imipramine; Iproniazid; Lanatosides; Mescaline; Methylphenidate; Morphine; Ouabain; Pentobarbital; Psychopharmacology; Reticulum; Rumen; Sheep; Theophylline | 1968 |
[Aggressive syndrome induced by apomorphine in rats].
Topics: Aggression; Animals; Apomorphine; Atropine; Humans; Male; Morphine; Rats; Time Factors; Tranquilizing Agents | 1968 |
Modification by disulfiram or methyltyrosine methylester (H 44-68) of abstinence symptoms in morphine-tolerant rats.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Depression, Chemical; Disulfiram; Dopamine; Drug Synergism; Drug Tolerance; Esters; Female; Humans; Male; Methyltyrosines; Morphine; Myocardium; Nalorphine; Norepinephrine; Rats; Stimulation, Chemical; Substance Withdrawal Syndrome | 1968 |
[Modification of central mechanisms of action by anticholinergics].
Topics: Aggression; Amphetamine; Animals; Apomorphine; Atropine; Biperiden; Bridged-Ring Compounds; Central Nervous System; Chlorpromazine; Depression, Chemical; Drug Synergism; Esters; Female; Hexobarbital; Humans; Imipramine; Male; Mice; Morphine; Nicotine; Parasympatholytics; Pentylenetetrazole; Perphenazine; Rats; Stimulation, Chemical; Strychnine; Tremorine | 1969 |
[Identification of alkaloids and purity testing of their salts. 3. Morpine].
Topics: Alkaloids; Apomorphine; Chromatography, Paper; In Vitro Techniques; Morphine | 1966 |
Release of intestinal 5-hydroxytryptamine by morphine and related agents.
Topics: Acetylcholine; Animals; Apomorphine; Calcium; Cocaine; Dogs; Female; Guinea Pigs; Ileum; Injections, Intravenous; Intestinal Mucosa; Intestines; Levorphanol; Male; Meperidine; Methadone; Morphine; Nalorphine; Nicotine; Rats; Reserpine; Serotonin; Tachyphylaxis; Uterus | 1967 |
The effect of melanotrophin release inhibiting factor (MIF) and cyclo (Leu-Gly) on the tolerance to morphine-induced antinociception in the rat: a dose-response study.
Topics: Analgesia; Animals; Apomorphine; Dipeptides; Dose-Response Relationship, Drug; Drug Tolerance; Hypothermia; Male; Morphine; MSH Release-Inhibiting Hormone; Neuropeptides; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1981 |
Central action of narcotic analgesics. VIII. The effect of dopaminergic stimulants on the action of analgesics in rats.
Topics: Amphetamine; Analgesics; Analgesics, Opioid; Animals; Apomorphine; Catalepsy; Codeine; Dopamine; Drug Interactions; Fentanyl; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Hypokinesia in mice and catalepsy in rats elicited by morphine associated with antidopaminergic agents, including atypical neuroleptics.
Topics: alpha-Methyltyrosine; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Clozapine; Haloperidol; Humans; Male; Methyltyrosines; Mice; Morphine; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Thioridazine | 1981 |
Morphine and [D-Met2,Pro5]enkephalinamide do not show specific neuroleptic activity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Conditioning, Classical; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Haloperidol; Humans; Male; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Rotation; Stereotyped Behavior | 1982 |
Contrasting interactions of pipradrol, d-amphetamine, cocaine, cocaine analogues, apomorphine and other drugs with conditioned reinforcement.
Topics: Animals; Apomorphine; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Dextroamphetamine; Flupenthixol; Male; Morphine; Piperidines; Rats; Reinforcement, Psychology | 1983 |
Quantitative assessment of jumping behaviour of morphine-like analgesics in mice.
Topics: Administration, Oral; Analgesics, Opioid; Animals; Antitussive Agents; Apomorphine; Dose-Response Relationship, Drug; Injections, Subcutaneous; Male; Mice; Morphine; Motor Activity | 1983 |
Interaction of opiates with dopamine receptors: receptor binding and behavioral assays.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Butaclamol; Dibenzocycloheptenes; Haloperidol; Kinetics; Male; Methadone; Morphine; Naloxone; Rats; Receptors, Dopamine; Spiperone | 1982 |
The effects of opiate agonists on growth hormone and prolactin release in rats.
Topics: Animals; Apomorphine; Enkephalins; Growth Hormone; Male; Methadone; Morphine; Naloxone; Naltrexone; Parasympathomimetics; Prolactin; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Opioid; Secretory Rate | 1980 |
Location and characterization of opiate receptors regulating pituitary secretion.
Topics: Animals; Apomorphine; Chromatography, Gel; Corpus Striatum; Endorphins; Enkephalins; Female; Growth Hormone; Hypothalamus; Luteinizing Hormone; Morphine; Naltrexone; Pituitary Gland, Anterior; Prolactin; Rats; Receptors, Opioid; Thyrotropin | 1980 |
Discriminative stimulus effects of prototype opiate receptor agonists in monkeys.
Topics: Animals; Apomorphine; Cyclazocine; Ethylketocyclazocine; Female; Generalization, Stimulus; Haloperidol; Male; Models, Biological; Morphine; Naltrexone; Phenazocine; Prejudice; Receptors, Opioid; Saimiri | 1980 |
Morphine dependence and dopaminergic activity: tests of circling responses in rats with unilateral nigral lesions.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Humans; Male; Morphine; Morphine Dependence; Motor Activity; Rats; Receptors, Dopamine; Receptors, Opioid; Substantia Nigra | 1980 |
Enkephalin receptors in the emetic chemoreceptor trigger zone of the dog.
Topics: Animals; Apomorphine; Chemoreceptor Cells; Dogs; Emetics; Enkephalins; Female; Injections, Intraventricular; Male; Morphine; Naloxone; Receptors, Opioid | 1981 |
Pharmacological generality of the Avfail effect.
Topics: Animals; Apomorphine; Atropine; Avoidance Learning; Chlordiazepoxide; Chlorides; Conditioning, Classical; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Lithium; Lithium Chloride; Male; Morphine; Pentobarbital; Rats; Taste | 1982 |
Potentiation of the aphrodisiac effect of N-n-propyl-norapomorphine by naloxone.
Topics: Adrenocorticotropic Hormone; Animals; Aphrodisiacs; Apomorphine; Dose-Response Relationship, Drug; Drug Synergism; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Apomorphine separates the antinociceptive effects of cholecystokinin octapeptide and ceruletide from those of morphine.
Topics: Analgesics; Animals; Apomorphine; Ceruletide; Male; Mice; Mice, Inbred Strains; Morphine; Sincalide | 1983 |
Evidence for a role of endogenous opioids in the nigrostriatal system: influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity.
Topics: Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Endorphins; Humans; Hydroxydopamines; Male; Morphine; Naloxone; Oxidopamine; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Sympathectomy, Chemical | 1983 |
On the mechanism of action of 2-amino-4-methylpyridine, a morphine-like analgesic.
Topics: Analgesics; Animals; Apomorphine; Drug Implants; Drug Interactions; Fenclonine; Humans; Male; Morphine; Picolines; Rats; Stereotyped Behavior; Thalamus | 1980 |
A study of dopaminergic mechanism in morphine induced Straub tail response.
Topics: Amphetamine; Animals; Apomorphine; Dopamine; Dose-Response Relationship, Drug; Female; Haloperidol; Male; Mice; Morphine; Muscle Spasticity; Pimozide; Tail | 1984 |
[Pharmacological action of eptazocine (l-1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine). Effects of eptazocine on spontaneous movements].
Topics: Analgesics; Animals; Apomorphine; Cyclazocine; Disulfiram; Haloperidol; Male; Morphine; Movement; Naloxone; Pentazocine; Rats; Rats, Inbred Strains | 1983 |
Psychoactive-drug response is affected by acute low-level microwave irradiation.
Topics: Amphetamines; Animals; Apomorphine; Behavior, Animal; Body Temperature Regulation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Male; Microwaves; Morphine; Psychotropic Drugs; Rats | 1983 |
[Electromyographic quantification of muscle rigidity in rats caused by morphine and drug actions on the symptoms].
Topics: Animals; Apomorphine; Electromyography; Male; Mephenesin; Morphine; Muscle Rigidity; Rats; Rats, Inbred Strains | 1983 |
Pharmacological screening of the nude mouse with respect to some neuroactive drugs.
Topics: Amitriptyline; Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Apomorphine; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Morphine; Nervous System; Stereotyped Behavior | 1983 |
Automated analysis of stereotypic behavior induced by psychomotor stimulants.
Topics: Amphetamine; Animals; Apomorphine; Autoanalysis; Drug Interactions; Haloperidol; Humans; Male; Methods; Morphine; Psychomotor Agitation; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1983 |
Effect of naloxone and morphine on dopamine agonist-induced stereotypy in rats and guinea pigs.
Topics: Amphetamine; Animals; Apomorphine; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Humans; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior | 1983 |
Reduction of morphine's effect on striatal dopamine metabolism in rats treated with a low dose of apomorphine or agents increasing serotonin transmission.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Fenfluramine; Male; Morphine; Piperazines; Rats; Serotonin | 1984 |
Comment on intrathecal morphine.
Topics: Apomorphine; Drug Stability; Morphine; Syringes | 1984 |
A device for the automated monitoring of stereotypic behavior.
Topics: Amphetamine; Animals; Apomorphine; Haloperidol; Humans; Male; Morphine; Motor Activity; Neurophysiology; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1982 |
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine | 1982 |
Morphine may mimic the apomorphine cue by inhibiting dopaminergic autoinhibition.
Topics: Animals; Apomorphine; Cues; Discrimination Learning; Dopamine; Dopamine Antagonists; Drug Interactions; Ergonovine; Male; Morphine; Rats; Rats, Inbred Strains | 1982 |
Gastric relaxation by intravenous and intracerebroventricular administration of apomorphine, morphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Dogs; Fentanyl; Injections, Intravenous; Injections, Intraventricular; Morphine; Stomach | 1982 |
Effects of chronic morphine treatment on dopamine-mediated turning behaviour in rats and mice with 6-hydroxydopamine-induced unilateral nigro-striatal lesions.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Humans; Hydroxydopamines; Mice; Morphine; Rats; Stereotyped Behavior; Substantia Nigra; Synapses | 1980 |
Effect of morphine on circling behaviour in rats with 6-hydroxydopamine striatal lesions and electrolesions of the raphe nucleus.
Topics: Animals; Apomorphine; Brain Stem; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Humans; Hydroxydopamines; Morphine; Neurons; Quipazine; Raphe Nuclei; Rats; Serotonin; Stereotyped Behavior | 1981 |
Modification of morphine-induced changes in striatal (3H)-spiroperidol binding and stereotype-behavior by cyclo(Leu-Gly).
Topics: Animals; Apomorphine; Butyrophenones; Corpus Striatum; Dipeptides; Humans; Male; Morphine; Neuropeptides; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Time Factors | 1982 |
Gastric relaxation and vomiting by apomorphine, morphine and fentanyl in the conscious dog.
Topics: Animals; Apomorphine; Dogs; Dopamine Antagonists; Drug Interactions; Female; Fentanyl; Morphine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naloxone; Pressure; Stomach; Vomiting | 1981 |
Effect of apomorphine on morphine-induced decrease in locomotor activity and increase in dopamine turnover in rats.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Locomotion; Male; Morphine; Rats | 1980 |
[Effect of psychodrugs on morphine effectivity (author's transl)].
Topics: Analgesia; Animals; Apomorphine; Clomipramine; Haloperidol; Male; Mice; Morphine; Time Factors | 1980 |
The effects of quipazine, fenfluramine and apomorphine on the morphine potentiation of tonic immobility.
Topics: Animals; Apomorphine; Brain; Chickens; Drug Synergism; Fenfluramine; Morphine; Motor Activity; Receptors, Dopamine; Receptors, Serotonin | 1981 |
On the mechanism of morphine action on rat striatal dopamine metabolsim.
Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Haloperidol; In Vitro Techniques; Morphine; Naloxone; Rats | 1980 |
Factors regulating drug cue sensitivity: the effect of training dose in fentanyl-saline discrimination.
Topics: Animals; Apomorphine; Cues; Cyclazocine; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Administration Schedule; Fentanyl; Generalization, Stimulus; Male; Morphine; Naloxone; Rats; Research Design; Sodium Chloride | 1980 |
Role of D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptors in morphine tolerance and dependence in mice.
Topics: Animals; Apomorphine; Azepines; Bromocriptine; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Tolerance; Mice; Mice, Inbred Strains; Morphine; Morphine Dependence; Naloxone; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate | 1995 |
Inhibition by ginseng total saponin of the development of morphine reverse tolerance and dopamine receptor supersensitivity in mice.
Topics: Animals; Apomorphine; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Panax; Plants, Medicinal; Receptors, Dopamine; Saponins | 1995 |
Differential involvement of voltage-dependent calcium channels in apomorphine-induced hypermotility and stereotypy.
Topics: Animals; Apomorphine; Calcium Channel Blockers; Calcium Channels; Electrophysiology; Electroshock; Male; Morphine; Motor Activity; Nifedipine; Rats; Rats, Wistar; Stereotyped Behavior; Substance Withdrawal Syndrome; Up-Regulation | 1994 |
Blockade of morphine reward through the activation of kappa-opioid receptors in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 3,4-Dihydroxyphenylacetic Acid; Analgesics; Animals; Apomorphine; Conditioning, Operant; Dopamine; Dynorphins; Homovanillic Acid; Injections, Subcutaneous; Limbic System; Male; Mice; Mice, Inbred Strains; Morphine; Motivation; Naltrexone; Peptide Fragments; Prosencephalon; Pyrrolidines; Receptors, Opioid, kappa; Reward | 1993 |
Morphine inhibits dopaminergic and cholinergic induced ejaculation in rats.
Topics: Animals; Apomorphine; Atropine; Cholinergic Agents; Dopamine Agents; Ejaculation; Ergolines; Male; Morphine; Naloxone; Physostigmine; Pilocarpine; Quinpirole; Rats; Sulpiride | 1994 |
Evidence that amplification of norepinephrine-induced LH release by morphine is indirectly due to suppression of tuberoinfundibular dopamine secretion.
Topics: Animals; Apomorphine; Dopamine Antagonists; Female; Haloperidol; Hypothalamus; Injections, Intraventricular; Luteinizing Hormone; Morphine; Norepinephrine; Prolactin; Rats; Rats, Sprague-Dawley | 1994 |
Effect of environmental and hypothalamic factors on thyrotropin secretion in the hypothyroid rat.
Topics: Animals; Apomorphine; Circadian Rhythm; Cold Temperature; Environmental Exposure; Ether; Hypothalamic Hormones; Hypothyroidism; Male; Morphine; Rats; Rats, Sprague-Dawley; Somatostatin; Stress, Physiological; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine | 1993 |
D-amphetamine-like stimulus properties are produced by morphine injections into the ventral tegmental area but not into the nucleus accumbens.
Topics: Animals; Apomorphine; Cues; Dextroamphetamine; Discrimination Learning; Discrimination, Psychological; Dopamine; Generalization, Stimulus; Injections; Male; Morphine; Motor Activity; Naloxone; Neurons; Nucleus Accumbens; Rats; Receptors, Opioid, mu; Reinforcement Schedule; Ventral Tegmental Area | 1993 |
The effect of 5-HT3 receptor antagonists on the morphine-induced excitation of A10 dopamine cells: electrophysiological studies.
Topics: Animals; Apomorphine; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Evoked Potentials; Indoles; Male; Morphine; Naloxone; Neurons; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tegmentum Mesencephali | 1994 |
Inhibition by MK-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice.
Topics: Animals; Apomorphine; Conditioning, Operant; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Narcotics; Receptors, Dopamine; Receptors, Neurotransmitter; Stereotyped Behavior | 1996 |
Low-dose apomorphine attenuates morphine-induced enhancement of brain stimulation reward.
Topics: Animals; Apomorphine; Brain; Dopamine Agonists; Dose-Response Relationship, Drug; Electrodes, Implanted; Male; Morphine; Narcotic Antagonists; Narcotics; Rats; Rats, Inbred F344; Reward; Self Stimulation | 1996 |
Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission.
Topics: Adrenalectomy; Animals; Antipsychotic Agents; Apomorphine; Corticosterone; Dopamine; Glial Fibrillary Acidic Protein; Glucocorticoids; Humans; Limbic System; Male; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Time Factors; Tyrosine 3-Monooxygenase | 1996 |
Differential influence of D1 and D2 dopamine receptors on acute opiate withdrawal in guinea-pig isolated ileum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Apomorphine; Dopamine Agents; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Pyrrolidines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1997 |
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: involvement of nitric oxide.
Topics: Analgesics, Opioid; Animals; Apomorphine; Benzeneacetamides; Dopamine Agonists; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Microdialysis; Morphine; Naloxone; Narcotic Antagonists; Nitrates; Nitric Oxide; Nitrites; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Yawning | 1997 |
The role of dopamine in the expression of morphine withdrawal.
Topics: Adrenergic Agents; Analgesia; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agents; Dopamine Antagonists; Hypothermia; Levodopa; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Oxidopamine; Substance Withdrawal Syndrome | 1998 |
Endogenous opioids and ATP-sensitive potassium channels are involved in the mediation of apomorphine-induced antinociception at the spinal level: a behavioral study in rats.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Dopamine Agonists; Endorphins; Female; Glyburide; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Nociceptors; Pain; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reaction Time; Spinal Cord | 1998 |
Prevention of apomorphine- or cisplatin-induced emesis in the dog by a combination of methylnaltrexone and morphine.
Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Apomorphine; Cisplatin; Dogs; Drug Interactions; Drug Therapy, Combination; Emetics; Male; Morphine; Naltrexone; Narcotics; Quaternary Ammonium Compounds; Vomiting | 1998 |
Effects of Ca2+ channel blockers on apomorphine, bromocriptine and morphine-induced locomotor activity in mice.
Topics: Amlodipine; Animals; Apomorphine; Benzazepines; Bromocriptine; Calcium Channel Blockers; Diltiazem; Dopamine Antagonists; Female; Haloperidol; Heterocyclic Compounds, 4 or More Rings; Mice; Morphine; Motor Activity; Nicardipine; Time Factors; Verapamil | 1999 |
Modification of naloxone-induced withdrawal signs by dextromethorphan in morphine-dependent mice.
Topics: Animals; Apomorphine; Behavior, Animal; Benzazepines; Dextromethorphan; Domperidone; Dopamine Agonists; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Grooming; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Pain; Substance Withdrawal Syndrome; Sulpiride | 1999 |
Involvement of mu-opioid receptors in potentiation of apomorphine-induced climbing behavior by morphine: studies using mu-opioid receptor gene knockout mice.
Topics: Analgesics, Opioid; Animals; Apomorphine; Brain Chemistry; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Haloperidol; Mice; Mice, Knockout; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu | 2000 |
Behavioral activation induced by D(2)-like receptor stimulation during opiate withdrawal.
Topics: Analgesics, Opioid; Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior; Substance Withdrawal Syndrome | 2000 |
Expression of fos-related antigens in the nucleus accumbens during opiate withdrawal and their attenuation by a D2 dopamine receptor agonist.
Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Agonists; Dopamine Antagonists; Immunohistochemistry; Lithium Chloride; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Substance Withdrawal Syndrome | 2000 |
The broad-spectrum anti-emetic activity of AS-8112, a novel dopamine D2, D3 and 5-HT3 receptors antagonist.
Topics: Animals; Antiemetics; Antineoplastic Agents; Apomorphine; Azepines; Colon; Dogs; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ferrets; Guinea Pigs; Hypothermia; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Narcotics; Pyridines; Receptors, Dopamine D3; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Tetrahydronaphthalenes; Vomiting | 2001 |
Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity.
Topics: Animals; Apomorphine; Baclofen; Drug Tolerance; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred ICR; Monitoring, Physiologic; Morphine; Motor Activity; Receptors, Dopamine; Synapses; Time Factors | 2001 |
Differential effects of morphine, DPDPE, and U-50488 on apomorphine-induced climbing behavior in mu-opioid receptor knockout mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Apomorphine; Dopamine Agonists; Enkephalin, D-Penicillamine (2,5)-; Female; Male; Mice; Mice, Knockout; Morphine; Motor Activity; Receptors, Opioid, mu | 2001 |
Inhibition of diazepam on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity.
Topics: Animals; Apomorphine; Diazepam; Dopamine; Dopamine Agonists; Drug Tolerance; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Narcotics; Receptors, Dopamine; Receptors, GABA-A | 2001 |
Central 5-HT(4) receptors and dopamine-dependent motor behaviors: searching for a functional role.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Catalepsy; Central Nervous System; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Indoles; Injections, Intraventricular; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior; Sulfonamides | 2002 |
Influence of benactyzine and derivatives on apomorphine-induced canine emesis and morphine-induced feline mania.
Topics: Animals; Apnea; Apomorphine; Benactyzine; Bipolar Disorder; Cats; Central Nervous System; Dogs; Morphine; Parasympatholytics; Vomiting | 1960 |
FREE RADICALS IN ALKALOIDAL COLOR IDENTIFICATION TESTS.
Topics: Apomorphine; Benzene; Chemistry, Pharmaceutical; Codeine; Free Radicals; Meperidine; Morphine; Papaverine; Pharmacy; Phenols; Research; Salicylic Acid; Spectrophotometry | 1964 |
[ACID-BASE TITRATIONS IN "ALCOHOLIC MEDIUM". 3. THE TITRATION OF SALTS DERIVED FROM AMPHOLYTES].
Topics: Apomorphine; Buffers; Chemistry, Pharmaceutical; Morphine; Opium; Pharmacy; Research; Salts | 1964 |
Role of nitric oxide in the acquisition and expression of apomorphine- or morphine-induced locomotor sensitization.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Mice; Morphine; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2003 |
[Treatment of manic-depressive psychoses with apomorphine].
Topics: Apomorphine; Bipolar Disorder; Humans; Mental Disorders; Morphine; Psychotic Disorders | 1950 |
[Biological therapy of chronic alcoholism with apomorphine].
Topics: Alcoholism; Apomorphine; Biological Therapy; Morphine | 1951 |
[Comment on current therapeutic methods in alcoholism: disintoxication, antabuse and apomorphine].
Topics: Alcoholism; Apomorphine; Disulfiram; Humans; Morphine | 1951 |
Calmodulin inhibitor trifluoperazine attenuates the development and expression of morphine-induced conditioned place preference in rats.
Topics: Animals; Apomorphine; Calcium Channel Blockers; Calmodulin; Conditioning, Psychological; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Trifluoperazine; Verapamil | 2004 |
[Biological treatment of chronic alcoholism with apomorphine].
Topics: Alcoholism; Apomorphine; Morphine | 1950 |
[Preservation of the emetic power of apomorphine injected subcutaneously in the presence of yohimbine].
Topics: Apomorphine; Emetics; Humans; Morphine; Yohimbine | 1950 |
Apomorphine in dogs.
Topics: Animals; Apomorphine; Dogs; Morphine | 1950 |
Repeated administration of dopaminergic agents in the dorsal hippocampus and morphine-induced place preference.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Conditioning, Classical; Dopamine Agonists; Dose-Response Relationship, Drug; Hippocampus; Injections, Subcutaneous; Male; Morphine; Narcotics; Quinpirole; Rats; Rats, Wistar; Reinforcement, Psychology; Space Perception | 2005 |
Influence of morphine- or apomorphine-induced sensitization on histamine state-dependent learning in the step-down passive avoidance test.
Topics: Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Dopamine Agents; Histamine; Injections, Intraventricular; Male; Memory; Mice; Morphine; Narcotics | 2006 |
Differential effects of micro-opioid, delta-opioid and kappa-opioid receptor agonists on dopamine receptor agonist-induced climbing behavior in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Apomorphine; Benzamides; Benzazepines; Dopamine Agonists; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Piperazines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrahydronaphthalenes | 2006 |
Analysis of the mechanism of antinociceptive action of niga-ichigoside F1 obtained from Rubus imperialis (Rosaceae).
Topics: Analgesics; Animals; Apomorphine; Atropine; Capsaicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glutamic Acid; Haloperidol; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Morphine; Naloxone; Nitroarginine; Pain; Pain Measurement; Plant Extracts; Rosaceae; Saponins; Yohimbine | 2006 |
Determination of morphine and apomorphine by the volumo-colorimetric method.
Topics: Apomorphine; Morphine; Morphine Derivatives | 1948 |
Contribution of dopamine receptors to periaqueductal gray-mediated antinociception.
Topics: Analgesics; Analgesics, Opioid; Animals; Apomorphine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Flupenthixol; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Microinjections; Microscopy, Confocal; Morphine; Nerve Fibers; Neurons; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Synaptic Transmission; Tyrosine 3-Monooxygenase | 2009 |
Effects of morphine on rat behaviour in the elevated plus maze: the role of central amygdala dopamine receptors.
Topics: Amygdala; Animals; Anxiety; Apomorphine; Benzazepines; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Maze Learning; Morphine; Narcotics; Random Allocation; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride | 2009 |
A note on apomorphine as a sedative.
Topics: Apomorphine; Humans; Hypnotics and Sedatives; Morphine | 1945 |
GABA neurons of the VTA drive conditioned place aversion.
Topics: Action Potentials; Analgesics, Opioid; Analysis of Variance; Animals; Apomorphine; Bacterial Proteins; Channelrhodopsins; Conditioning, Operant; Dopamine Agonists; Dopamine Antagonists; Dopaminergic Neurons; Electroshock; Escape Reaction; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABAergic Neurons; Glutamate Decarboxylase; Haloperidol; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morphine; Optics and Photonics; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2012 |
Increased dopamine receptor activity in the nucleus accumbens shell ameliorates anxiety during drug withdrawal.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Anxiety; Apomorphine; Benzazepines; Conditioning, Operant; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Male; Morphine; Nucleus Accumbens; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reflex, Startle; Substance Withdrawal Syndrome | 2012 |
Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal.
Topics: Action Potentials; Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopaminergic Neurons; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reward; Signal Transduction; Substance Withdrawal Syndrome; Time Factors; Ventral Tegmental Area | 2014 |
APOMORPHINE treatment for morphine addiction.
Topics: Apomorphine; Humans; Morphine; Morphine Dependence | 1949 |
Preparation and Characterization of a Monoclonal Antibody Against Morphine.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Apomorphine; Codeine; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Hybridomas; Immunization; Immunoassay; Immunoglobulin G; Mice; Mice, Inbred BALB C; Morphine | 2015 |
Activation of adenosine A₂A receptors suppresses the emission of pro-social and drug-stimulated 50-kHz ultrasonic vocalizations in rats: possible relevance to reward and motivation.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Amphetamine; Animals; Apomorphine; Caffeine; Central Nervous System Stimulants; Dopamine Agonists; Interpersonal Relations; Male; Morphine; Motivation; Motor Activity; Narcotics; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Reward; Social Behavior; Vocalization, Animal | 2016 |
Enhanced antinociception with repeated microinjections of apomorphine into the periaqueductal gray of male and female rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Apomorphine; Dopamine; Dopamine Agonists; Dopaminergic Neurons; Drug Tolerance; Female; Male; Microinjections; Morphine; Narcotic Antagonists; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 2018 |
Reversal of morphine conditioned behavior by an anti-dopaminergic post-trial drug treatment during re-consolidation.
Topics: Analgesics, Opioid; Animals; Apomorphine; Conditioning, Operant; Dopamine Agonists; Dose-Response Relationship, Drug; Hyperkinesis; Locomotion; Male; Morphine; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors | 2019 |
Post-trial low dose apomorphine prevents the development of morphine sensitization.
Topics: Animals; Apomorphine; Behavior, Animal; Central Nervous System Sensitization; Conditioning, Classical; Dopamine Agonists; Male; Memory Consolidation; Morphine; Narcotics; Rats; Rats, Wistar | 2020 |
Morphine and dopamine: Low dose apomorphine can prevent both the induction and expression of morphine locomotor sensitization and conditioning.
Topics: Animals; Apomorphine; Dopamine; Dopamine Agonists; Morphine; Motor Activity; Rats; Rats, Wistar | 2023 |