Page last updated: 2024-08-17

apomorphine and indomethacin

apomorphine has been researched along with indomethacin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdel-Halim, MS; Anggård, E; Sjöquist, B1
Collier, HO; McDonald-Gibson, WJ; Saeed, SA1
Khanna, N; Ray, A; Sen, P1
Briggs, DB; Carpenter, DO; Knox, AP; Strominger, NL1
Bianchine, JR; Schwarz, RD; Uretsky, NJ1
Ivanovska, N; Philipov, S1
Akiba, Y; Kaunitz, JD; Satoh, H; Urushidani, T1

Reviews

1 review(s) available for apomorphine and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for apomorphine and indomethacin

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Prostaglandin synthesis inhibition and monoamine metabolites in the rat brain.
    Prostaglandins, 1979, Volume: 18, Issue:6

    Topics: Animals; Apomorphine; Brain; Chlorpromazine; Corpus Striatum; Gas Chromatography-Mass Spectrometry; Glycols; Homovanillic Acid; Hydroxyindoleacetic Acid; Indomethacin; Male; Methoxyhydroxyphenylglycol; Morphine; Olfactory Bulb; Phenylacetates; Rats

1979
Inhibition by drugs of the stimulation of prostaglandin biosynthesis induced by apomorphine.
    Advances in prostaglandin and thromboxane research, 1976, Volume: 1

    Topics: Animals; Antidepressive Agents; Antiemetics; Apomorphine; Aspirin; Cattle; Cell-Free System; Cyclooxygenase Inhibitors; Ergotamine; Indomethacin; Male; Prostaglandins; Seminal Vesicles

1976
Possible prostaglandin-dopamine interactions during experimental gastric ulcer formation.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:6

    Topics: Animals; Apomorphine; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological

1990
Radiation-induced emesis in the dog: effects of lesions and drugs.
    Radiation research, 1986, Volume: 108, Issue:3

    Topics: Animals; Apomorphine; Cerebral Ventricles; Dogs; Domperidone; Indomethacin; Neurons; Prostaglandins; Radiation Injuries, Experimental; Vagus Nerve; Vomiting

1986
Prostaglandin inhibition of apomorphine-induced circling in mice.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6

    Topics: Animals; Apomorphine; Brain; Corpus Striatum; Dextroamphetamine; Humans; Hydroxydopamines; Indomethacin; Injections, Intraventricular; Male; Muridae; Neural Pathways; Oxidopamine; Prostaglandins; Receptors, Dopamine; Stereotyped Behavior; Synapses

1982
A low dose immunorestorative effect of aporphinoid alkaloid oxoglaucine on experimentally immunosuppressed and infected mice.
    Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Apomorphine; Artemisinins; Cyclophosphamide; Drug Interactions; Erythrocytes; Hypersensitivity, Delayed; Immunosuppressive Agents; Indomethacin; Klebsiella Infections; Klebsiella pneumoniae; Male; Mice; Prednisolone; Sesquiterpenes; Sheep

1997
Gastroparesis Worsens Indomethacin-Induced Gastric Antral Ulcers by Bile Reflux via Activation of 5-HT
    Digestive diseases and sciences, 2023, Volume: 68, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Apomorphine; Atropine; Bile Reflux; Cholestyramine Resin; Dopamine; Duodenogastric Reflux; Gastroparesis; Haloperidol; Indomethacin; Mice; Ondansetron; Serotonin; Stomach Ulcer; Ulcer

2023