Page last updated: 2024-08-17

apomorphine and idazoxan

apomorphine has been researched along with idazoxan in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's6 (46.15)18.2507
2000's3 (23.08)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Lookingland, KJ; Moore, KE; Tian, Y1
Dresse, A; Giesbers, I; Massotte, L; Scuvée-Moreau, J; Seutin, V1
Dickinson, SL; Gadie, B; Tulloch, IF1
Carter, R; Shuster, S1
Ikeda, T; Matsumoto, M; Saito, H; Togashi, H; Yoshioka, M1
Lawler, CP; Mailman, RB; Nichols, DE; Smith, HP1
Chopin, P; Colpaert, F; Marien, M; Martel, J1
Chopin, P; Colpaert, FC; Marien, M1
Brotchie, JM; Crossman, AR; Fox, SH; Henry, B; Hill, MP; Peggs, D1
Schmidt, WJ; Srinivasan, J1

Other Studies

13 other study(ies) available for apomorphine and idazoxan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Contribution of noradrenergic neurons to 3,4-dihydroxyphenylacetic acid concentrations in the regions of the rat brain containing incertohypothalamic dopaminergic neurons.
    Brain research, 1991, Jul-26, Volume: 555, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Apomorphine; Brain Chemistry; Dioxanes; Dopamine; Haloperidol; Hydrolysis; Hypothalamus; Idazoxan; Injections, Intravenous; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats

1991
Effect of BHT 920 on monoaminergic neurons of the rat brain: an electrophysiological in vivo and in vitro study.
    Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:5

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; Azepines; Biogenic Monoamines; Brain; Clonidine; Dioxanes; Dopamine Agents; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Sulpiride; Tegmentum Mesencephali

1990
Alpha 1- and alpha 2-adrenoreceptor antagonists differentially influence locomotor and stereotyped behaviour induced by d-amphetamine and apomorphine in the rat.
    Psychopharmacology, 1988, Volume: 96, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Dextroamphetamine; Dioxanes; Idazoxan; Male; Motor Activity; Prazosin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors

1988
Dopamine stimulates alpha 2-adrenoceptors on the Anolis melanophore.
    European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4

    Topics: Animals; Apomorphine; Binding, Competitive; Dioxanes; Dopamine; Dose-Response Relationship, Drug; Idazoxan; Lizards; Melanocyte-Stimulating Hormones; Melanophores; Receptors, Adrenergic, alpha; Skin Pigmentation; Sulpiride; Yohimbine

1983
Functional regulation by dopamine receptors of serotonin release from the rat hippocampus: in vivo microdialysis study.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Fluoresceins; Fluoxetine; Hippocampus; Idazoxan; Male; Microdialysis; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine; Selective Serotonin Reuptake Inhibitors; Serotonin; Tetrodotoxin

1996
Locomotor inhibition, yawning and vacuous chewing induced by a novel dopamine D2 post-synaptic receptor agonist.
    European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Apomorphine; Benzazepines; Computer Simulation; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Locomotion; Male; Mastication; Phenanthridines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Reference Standards; Remoxipride; Stereoisomerism; Yawning

1997
Neuroprotective effects of the alpha2-adrenoceptor antagonists, (+)-efaroxan and (+/-)-idazoxan, against quinolinic acid-induced lesions of the rat striatum.
    Experimental neurology, 1998, Volume: 154, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Benzofurans; Choline O-Acetyltransferase; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Enzyme Activation; Huntington Disease; Idazoxan; Imidazoles; Male; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2

1998
Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Apomorphine; Behavior, Animal; Benzofurans; Brimonidine Tartrate; Clonidine; Dopamine Agonists; Idazoxan; Imidazoles; Ligands; Male; Methylphenidate; Oxidopamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Stereoisomerism; Stereotyped Behavior; Substantia Nigra

1999
Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: evidence from the effects of the alpha(2) adrenoceptor antagonist idazoxan.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Apomorphine; Callithrix; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Globus Pallidus; Idazoxan; Levodopa; Male; Neurologic Examination; Neurons; Norepinephrine; Substantia Nigra

2001
Serotonergic influence on the potentiation of D-amphetamine and apomorphine-induced rotational behavior by the alpha2-adrenoceptor antagonist 2-methoxy idazoxan in hemiparkinsonian rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:9

    Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Dextroamphetamine; Drug Synergism; Idazoxan; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Serotonin; Sympatholytics

2005