apomorphine has been researched along with fluphenazine in 95 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 78 (82.11) | 18.7374 |
1990's | 11 (11.58) | 18.2507 |
2000's | 3 (3.16) | 29.6817 |
2010's | 3 (3.16) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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George, SR; Guan, HC; Laurier, LG; Ng, G; Niznik, HB; O'Dowd, BF; Seeman, P; Sunahara, RK; Torchia, J; Van Tol, HH | 1 |
Butler, DE; Coughenour, LL; DeWald, HA; Downs, DA; Heffner, TG; Lustgarten, D; Pugsley, TA; Wise, LD | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Florence, AT; Jenkins, AW; Loveless, AH | 1 |
Dismukes, K; Mulder, AH | 1 |
Di Chiara, G; Loddo, P; Spano, PF; Tonon, GC; Trabucchi, M | 1 |
Clement-Cormier, YC; Robison, GA | 1 |
Dlabac, A; Kazdová, E; Likovský, Z; Votava, Z | 1 |
Poat, JA; Watling, KJ; Woodruff, GN | 1 |
Brown, JH; Makman, MH; Mishra, RK | 1 |
Schorderet, M | 1 |
Dreyfuss, J; Miller, I; Ross, JJ; Schreiber, EC; Shaw, JM | 2 |
Creese, I; Snyder, SH; Stewart, K | 1 |
Choi, RL; Roth, RH | 1 |
Chen, PC | 1 |
Nowycky, MC; Roth, RH | 1 |
Berry, MS; MacDonald, JF | 1 |
Ahn, HS; Demirjian, C; Makman, MH; Mishra, RK | 1 |
Burt, DR; Creese, I; Snyder, SH | 1 |
Couper, GS; Huprikar, SV; Mellow, AM; Moody, RR; Zeller, EA | 1 |
Di Chiara, G; Spano, PF; Tonon, GC; Trabucchi, M | 1 |
Herr, F; Voith, K | 1 |
Costall, B; Naylor, RJ | 1 |
Burt, DR; Creese, I; Synder, SH | 1 |
Alvir, JM; Ashtari, M; Bilder, RM; Bogerts, B; Degreef, G; Geisler, SH; Lieberman, JA; Loebel, A; Mayerhoff, DI; Woerner, M | 1 |
Baldessarini, RJ; Booth, RG; Campbell, A | 1 |
Barnes, JM; Barnes, NM; Costall, B; Naylor, RJ | 1 |
Costall, B; Domeney, AM; Naylor, RJ; Owera-Atepo, JB; Rudd, JA; Tattersall, FD | 1 |
Arbilla, S; Dahl, SG; Langer, SZ; Nowak, JZ | 1 |
Costall, B; Domeney, AM; Naylor, RJ | 1 |
Peris, J; Zahniser, NR | 1 |
Hietala, J | 1 |
Carvey, P; Goetz, CG; Klawans, HL; Tanner, CM | 1 |
Salama, AI; Saller, CF | 1 |
Bourin, M; Larousse, C; Poisson, L | 1 |
Dahl, SG; Lloyd, KG; Morel, E | 1 |
Finch, CE; Morgan, DG | 1 |
Thermos, K; Weiss, B; Winkler, JD | 2 |
Agui, T; Amlaiky, N; Caron, MG; Kebabian, JW | 1 |
Malenka, RC; Nicoll, RA | 1 |
Wreggett, KA | 1 |
Hietala, J; MacDonald, E; Scheinin, M; Syvälahti, E | 1 |
Carvey, PM; Goetz, CG; Klawans, HL; Nelson, D; Tanner, CM | 1 |
Daw, NW; Jensen, RJ | 1 |
Johnston, S; Merali, Z; Sistek, J | 1 |
Bourat, G; Ducrot, R; Fournel, J; Garret, C; Julou, L | 1 |
Brown, JH; Makman, MH | 1 |
Forn, J; Greengard, P; Krueger, BK | 1 |
Stille, G | 1 |
Dlabac, A; Kazdová, E | 2 |
Lauener, H; Stille, G | 1 |
Nymark, M | 1 |
Fjalland, B; Moller Nielsen, I; Nymark, M; Pedersen, V | 1 |
Baran, L; Maj, J; Sarnek, J; Sowińska, H | 1 |
Soyka, D | 1 |
Janssen, PA; Lenaerts, FM; Niemegeers, CJ; Schellekens, KH | 1 |
Boissier, JR; Lwoff, JM; Simon, P | 1 |
Hansson, E; Rönnbäck, L; Sellström, A | 1 |
Langwiński, R; Niedzielski, J | 1 |
Bracha, HS; Davis, KL; Kendler, KS | 1 |
Mori, J; Satoh, H; Satoh, Y | 1 |
Beal, MF; Martin, JB | 1 |
Király, I; Van Ree, JM | 1 |
Czuczwar, SJ; Kleinrok, Z; Kozicka, M | 1 |
Forster, A; Magistretti, PJ; Schorderet, M | 1 |
Cote, TE; Grewe, CW; Kebabian, JW | 1 |
Cote, TE; Eskay, RL; Frey, EA; Grewe, CW; Kebabian, JW; Munemura, M; Stoof, JC; Tsuruta, K | 1 |
Cote, TE; Grewe, CW; Kebabian, JW; Tsuruta, K | 1 |
Rubin, EH; Wooten, GF | 1 |
Anderson, K; Miller, D; Szkrybalo, M; Turowski, B; Uretsky, N | 1 |
Herman, ZS; Kowalski, J; Przewłocki, R; Trzeciak, H | 1 |
Carvey, PM; Goetz, CG; Klawans, HL; Tanner, CM | 1 |
Benson, DI; Kuhn, CM; Meyerson, LR; Stanley, M; Virgilio, J; Wazer, D | 1 |
Furukawa, T; Yamada, K | 1 |
Costall, B; Naylor, RJ; Nohria, V | 1 |
Cote, TE; Frey, EA; Grewe, CW; Kebabian, JW | 1 |
Delanoy, RL; Dunn, AJ | 1 |
Roth, RH; Wheeler, SC | 1 |
Gamble, SJ; Waddington, JL | 1 |
Ehlert, FJ; Roeske, WR; Yamamura, HI | 1 |
Kamiya, HO; Kohjimoto, Y; Takano, Y | 1 |
Friedhoff, AJ; Rosengarten, H; Schweitzer, JW | 1 |
Baldessarini, RJ; Campbell, A; Neumeyer, JL | 1 |
Camp-Bruno, JA; Lee, KL; Lifshitz, K; Linn, GS; O'Keeffe, RT; Suckow, RF | 1 |
Baldessarini, RJ; Kula, NS; Neumeyer, JL; Tarazi, FI; Yeghiayan, SK | 1 |
Davidkova, G; Morabito, M; Weiss, B; Zhang, SP; Zhou, LW | 1 |
BURKMAN, AM | 1 |
Byers, DM; Del Val, S; Irwin, LN; Moss, DE; Sumaya, IC | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
2 review(s) available for apomorphine and fluphenazine
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The activity of substituted benzamides in biochemical models of dopamine receptors.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Benzamides; Cyclic AMP; Dopamine; Fluphenazine; History, 20th Century; Isoproterenol; Models, Biological; Pituitary Gland; Receptors, Dopamine; Sulpiride | 1982 |
2 trial(s) available for apomorphine and fluphenazine
Article | Year |
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Prospective study of psychobiology in first-episode schizophrenia at Hillside Hospital.
Topics: Adolescent; Adult; Analysis of Variance; Apomorphine; Brain; Female; Fluphenazine; Follow-Up Studies; Growth Hormone; Humans; Magnetic Resonance Imaging; Male; Methylphenidate; Prognosis; Prospective Studies; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology | 1992 |
[The effect of psychopharmacological drugs and other central nervous system effecting drugs on experimental nystagmus].
Topics: Amitriptyline; Apomorphine; Aporphines; Barbiturates; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Diazepam; Dimenhydrinate; Eye Movements; Fluphenazine; Haloperidol; Humans; Imipramine; Schizophrenia; Thioridazine; Triflupromazine | 1968 |
91 other study(ies) available for apomorphine and fluphenazine
Article | Year |
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Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain; Cell Line; Cell Membrane; Cloning, Molecular; Dopamine; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligonucleotide Probes; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D5; RNA, Messenger; Sequence Homology, Nucleic Acid; Transfection | 1991 |
(5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones . A series of novel potential antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Apomorphine; Ataxia; Avoidance Learning; Brain; Cebus; Chemical Phenomena; Chemistry; Dopamine; Male; Mice; Motor Activity; Movement Disorders; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Dopamine; Saimiri | 1986 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Effect of formulation of intramuscular injections of phenothiazines on duration of activity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dogs; Emulsions; Female; Fluphenazine; Gels; Injections, Intramuscular; Male; Phenothiazines; Polyethylene Glycols; Solubility; Solutions; Suspensions; Time Factors; Trifluoperazine | 1976 |
Effects of neuroleptics on release of 3H-dopamine from slices of rat corpus striatum.
Topics: Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Cocaine; Corpus Striatum; Dopamine; Electric Stimulation; Fluphenazine; Haloperidol; Male; Rats; Spiperone | 1977 |
Dopamine-stimulated adenylate cyclase in rat substantia nigra: localization and effects of neuroleptics.
Topics: Adenylyl Cyclases; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Dopamine; Fluphenazine; Haloperidol; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Rats; Substantia Nigra; Sulpiride | 1977 |
Adenylate cyclase from various dopaminergic areas of the brain and the action of antipsychotic drugs.
Topics: Adenylyl Cyclases; Amygdala; Animals; Antipsychotic Agents; Apomorphine; Brain; Caudate Nucleus; Clozapine; Dopamine; Fluphenazine; Isoproterenol; Loxapine; Median Eminence; Norepinephrine; Olfactory Bulb; Rats | 1977 |
[Pharmacologic effect of protracted neuroleptics, fluphenazine oenanthate and oxyprothepine oenanthate (VUFB 9447)].
Topics: Animals; Apomorphine; Delayed-Action Preparations; Dibenzothiepins; Dogs; Drug Evaluation, Preclinical; Electroencephalography; Escape Reaction; Fluphenazine; Male; Psychopharmacology; Rabbits; Rats; Vomiting | 1975 |
Dopamine-sensitive adenylate cyclase in homogenates of rat nucleus accumbens: structure-activity studies and effects of agonists and antagonists.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Apomorphine; Dopamine; Dopamine Antagonists; Flupenthixol; Fluphenazine; Male; Nucleus Accumbens; Phenethylamines; Phentolamine; Propranolol; Rats; Receptors, Dopamine; Salsoline Alkaloids; Septal Nuclei; Structure-Activity Relationship | 1979 |
Cyclic AMP in retina and caudate nucleus: influence of dopamine and other agents.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Cyclic AMP; Dopamine; Epinephrine; Ergotamine; Fluphenazine; Haloperidol; Isoproterenol; Lysergic Acid Diethylamide; Norepinephrine; Ouabain; Phentolamine; Potassium; Propranolol; Retina; Species Specificity | 1975 |
Dopamine-mimetic activity of ergot derivatives, as measured by the production of cyclic AMP in isolated retinae of the rabbit.
Topics: Animals; Apomorphine; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Ergolines; Ergonovine; Ergot Alkaloids; Fluphenazine; Lithium; Rabbits; Retina | 1978 |
Depot fluphenazine enanthate and decanoate: comparative rates of release in dogs.
Topics: Animals; Apomorphine; Biological Availability; Delayed-Action Preparations; Dogs; Esters; Fluphenazine; Male; Time Factors | 1975 |
Species variation in dopamine receptor binding.
Topics: Animals; Apomorphine; Binding, Competitive; Brain; Cattle; Caudate Nucleus; Fluphenazine; Haloperidol; Humans; In Vitro Techniques; Male; Rats; Receptors, Dopamine; Species Specificity; Spiperone; Tetrahydronaphthalenes | 1979 |
Development of supersensitivity of apomorphine-induced increases in acetylcholine levels and stereotype after chronic fluphenazine treatment.
Topics: Acetylcholine; Animals; Apomorphine; Behavior; Corpus Striatum; Drug Interactions; Fluphenazine; Humans; Male; Olfactory Bulb; Rats; Stereotyped Behavior; Time Factors | 1978 |
[Pharmacological studies of long-acting phenothiazines with particular reference to fluphenazine decanoate (author's transl)].
Topics: Animals; Apomorphine; Blood Pressure; Body Temperature; Brain; Catalepsy; Catecholamines; Electrocardiography; Fluphenazine; Guinea Pigs; Humans; In Vitro Techniques; Injections, Subcutaneous; Locomotion; Male; Methamphetamine; Mice; Rats; Time Factors | 1978 |
Presynaptic dopamine receptors. Development of supersensitivity following treatment with fluphenazine decanoate.
Topics: Animals; Apomorphine; Fluphenazine; Male; Olfactory Bulb; Piribedil; Rats; Receptors, Dopamine; Time Factors | 1977 |
Further identification of multiple responses mediated by dopamine in the CNS of Planorbis corneus.
Topics: Animals; Apomorphine; Central Nervous System; Dopamine; Evoked Potentials; Fluphenazine; Ganglia; Haloperidol; In Vitro Techniques; Lysergic Acid Diethylamide; Metoclopramide; Mollusca; Tubocurarine | 1978 |
Catecholamine-sensitive adenylate cyclase in frontal cortex of primate brain.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Calcium; Catecholamines; Cerebral Cortex; Clozapine; Dopamine; Drug Combinations; Fluphenazine; Frontal Lobe; Guanosine Triphosphate; Haloperidol; Haplorhini; Isoproterenol; Macaca mulatta; Norepinephrine; Phentolamine; Receptors, Adrenergic; Receptors, Dopamine; Sodium Fluoride; Time Factors | 1976 |
Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain.
Topics: Animals; Apomorphine; Corpus Striatum; Dextroamphetamine; Dose-Response Relationship, Drug; Fluphenazine; Haloperidol; Kinetics; Rats; Receptors, Dopamine; Reserpine; Time Factors; Tranquilizing Agents | 1977 |
Mescaline: its effects on learning rate and dopamine metabolism in goldfish (Carassius auratus).
Topics: Animals; Apomorphine; Avoidance Learning; Brain; Dopamine; Fluphenazine; Goldfish; Levodopa; Mescaline; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Serotonin | 1976 |
A dopamine-stimulated adenylate cyclase in rat substantia nigra.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Dopamine; Fluphenazine; Haloperidol; Isoproterenol; Male; Norepinephrine; Phentolamine; Propranolol; Rats; Stimulation, Chemical; Substantia Nigra | 1976 |
The behavioral pharmacology of butaclamol hydrochloride (AY-23,028), a new potent neuroleptic drug.
Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Catalepsy; Chlorpromazine; Dextroamphetamine; Dibenzocycloheptenes; Discrimination Learning; Dogs; Epinephrine; Fluphenazine; Humans; Male; Mice; Motor Activity; Quinolizines; Rats; Stereotyped Behavior; Tranquilizing Agents; Vomiting | 1975 |
Detection of the nueroleptic properties of clozapine, sulpiride and thioridazine.
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Clozapine; Dextroamphetamine; Dibenzazepines; Dose-Response Relationship, Drug; Drug Synergism; Fluphenazine; Haloperidol; Humans; Isoquinolines; Male; Methyltyrosines; Pimozide; Rats; Spiro Compounds; Stereotyped Behavior; Succinimides; Sulpiride; Thioridazine; Tranquilizing Agents | 1975 |
The dopamine receptor: differential binding of d-LSD and related agents to agonist and antagonist states.
Topics: Animals; Apomorphine; Binding, Competitive; Cattle; Caudate Nucleus; Cyproheptadine; Dopamine; Fluphenazine; Haloperidol; Lysergic Acid Diethylamide; Methiothepin; Receptors, Drug; Stereoisomerism | 1975 |
Release and elimination of 14C-fluphenazine enanthate and decanoate esters administered in sesame oil to dogs.
Topics: Animals; Apomorphine; Dogs; Feces; Fluphenazine; Half-Life; Kinetics; Male; Oils; Pharmaceutical Vehicles; Time Factors | 1976 |
Inhibition of dopamine synthesis in rat striatal minces: evidence of dopamine autoreceptor supersensitivity to S(+)- but not R(-)-N-n-propylnorapomorphine after pretreatment with fluphenazine.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Fluphenazine; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Tyrosine 3-Monooxygenase | 1991 |
The actions of (-)N-n-propylnorapomorphine and selective dopamine D1 and D2 receptor agonists to modify the release of [3H]dopamine from the rat nucleus accumbens.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Benzazepines; Dopamine; Dopamine Agents; Ergolines; Female; Fluphenazine; Motor Activity; Nucleus Accumbens; Potassium; Quinpirole; Rats; Receptors, Dopamine; Septal Nuclei; Sulpiride | 1990 |
Fluphenazine, ICS 205-930 and dl-fenfluramine differentially antagonise drug-induced emesis in the ferret.
Topics: Animals; Apomorphine; Cisplatin; Copper; Copper Sulfate; Emetics; Female; Fenfluramine; Ferrets; Fluphenazine; Indoles; Ipecac; Lisuride; Male; Stereoisomerism; Tropisetron; Vomiting | 1990 |
Antagonism of presynaptic dopamine receptors by phenothiazine drug metabolites.
Topics: Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dopamine; Electric Stimulation; Fluphenazine; Male; Methotrimeprazine; Rabbits; Receptors, Dopamine | 1990 |
Desenkephalin-gamma-endorphin is an antagonist of the hyperactivity response induced by infusion of dopamine into the nucleus accumbens of rat and ventral striatum of marmoset.
Topics: Animals; Apomorphine; beta-Endorphin; Callitrichinae; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Female; Fluphenazine; Haloperidol; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei | 1989 |
Persistent augmented dopamine release after acute cocaine requires dopamine receptor activation.
Topics: Animals; Apomorphine; Benzazepines; Cocaine; Dopamine; Dopamine Antagonists; Fluphenazine; Lidocaine; Male; Mazindol; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride | 1989 |
Effects of DA-1- and DA-2-dopamine antagonists on apomorphine-induced inhibition of peripheral sympathetic neurotransmission.
Topics: Animals; Apomorphine; Blood Pressure; Domperidone; Dopamine Antagonists; Electric Stimulation; Fluphenazine; Haloperidol; Male; Peripheral Nerves; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Sympathetic Nervous System; Synaptic Transmission; Vasoconstriction | 1988 |
The pathophysiology of tardive dyskinesia.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Chlorpromazine; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Fluphenazine; Guinea Pigs; Haloperidol; Humans; Receptors, Dopamine; Stereotyped Behavior; Thioridazine; Time Factors | 1985 |
3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds.
Topics: 4-Butyrolactone; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Buspirone; Carbazoles; Chlorpromazine; Clozapine; Corpus Striatum; Dopamine; Dopamine Antagonists; Fluphenazine; Haloperidol; Male; Molindone; Pargyline; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Regression Analysis | 1986 |
Piracetam interactions with neuroleptics in psychopharmacological tests.
Topics: Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Drug Interactions; Fluphenazine; Haloperidol; Hypothermia; Male; Mice; Piracetam; Pyrrolidinones; Sulpiride | 1986 |
Anti-apomorphine effects of phenothiazine drug metabolites.
Topics: Animals; Antipsychotic Agents; Apomorphine; Body Temperature; Fluphenazine; Male; Methotrimeprazine; Mice; Motor Activity | 1987 |
[3H]Fluphenazine binding to brain membranes: simultaneous measurement of D-1 and D-2 receptor sites.
Topics: Animals; Apomorphine; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Corpus Striatum; Fluphenazine; Kinetics; Male; Mice; Mice, Inbred C57BL; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Tissue Distribution | 1986 |
Differential effects of fluphenazine-N-mustard, on calmodulin activity and on D1 and D2 dopaminergic responses.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Benzazepines; Calmodulin; Corpus Striatum; Ergolines; Fluphenazine; Male; Mice; Quinpirole; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior | 1987 |
Binding of [125I]-N-(p-aminophenethyl)spiroperidol to the D-2 dopamine receptor in the neurointermediate lobe of the rat pituitary gland: a thermodynamic study.
Topics: Animals; Apomorphine; Female; Fluphenazine; Guanylyl Imidodiphosphate; In Vitro Techniques; Iodine Radioisotopes; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Spiperone; Thermodynamics | 1988 |
Dopamine decreases the calcium-activated afterhyperpolarization in hippocampal CA1 pyramidal cells.
Topics: Action Potentials; Animals; Apomorphine; Calcium; Dopamine; Fluphenazine; Guinea Pigs; Hippocampus; Kinetics; Norepinephrine; Potassium; Rats; Receptors, Dopamine; Synaptic Transmission | 1986 |
Alkylation of the bovine anterior pituitary D2-dopamine receptor: inconsistency with predictions of the ternary complex model.
Topics: Alkylation; Animals; Apomorphine; Binding, Competitive; Cattle; Cell Membrane; Computer Simulation; Dopamine Antagonists; Fluphenazine; GTP-Binding Proteins; In Vitro Techniques; Ligands; Pituitary Gland, Anterior; Receptors, Dopamine; Spiperone; Structure-Activity Relationship | 1987 |
Comparison of the effects of fluphenazine-N-mustard on dopamine binding sites and on behavior induced by apomorphine in supersensitive mice.
Topics: Animals; Apomorphine; Binding, Competitive; Fluphenazine; Hydroxydopamines; Male; Mice; Oxidopamine; Receptors, Dopamine; Spiperone; Stereotyped Behavior | 1987 |
Alterations in peripheral and central dopamine receptor sensitivity after subchronic treatment with fluphenazine and sulpiride.
Topics: Animals; Apomorphine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Fluphenazine; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Sulpiride; Vasoconstriction | 1987 |
The effect of thioridazine on haloperidol induced behavioral hypersensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Fluphenazine; Haloperidol; Male; Motor Activity; Rats; Receptors, Muscarinic; Stereotyped Behavior; Thioridazine | 1986 |
Effects of dopamine and its agonists and antagonists on the receptive field properties of ganglion cells in the rabbit retina.
Topics: Action Potentials; Animals; Apomorphine; Dopamine; Dopamine Antagonists; Flupenthixol; Fluphenazine; Haloperidol; Photic Stimulation; Rabbits; Reaction Time; Receptors, Dopamine; Retina; Retinal Ganglion Cells; Sulpiride; Visual Fields | 1986 |
Role of dopaminergic system(s) in mediation of the behavioural effects of bombesin.
Topics: Animals; Apomorphine; Behavior, Animal; Bombesin; Dextroamphetamine; Dose-Response Relationship, Drug; Fluphenazine; Hydroxydopamines; Injections, Intraventricular; Male; Motor Activity; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1985 |
Pharmacological study of pipotiazine (19.366 R.P.) and its undecylenic (19.551 R.P.) and palmitic (19.552 R.P.) esters.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Catalepsy; Dogs; Esters; Fluphenazine; Guinea Pigs; Humans; Lethal Dose 50; Mice; Motor Activity; Palmitic Acids; Phenothiazines; Piperidines; Rats; Respiration; Sleep; Species Specificity; Sulfonamides; Time Factors; Undecylenic Acids | 1973 |
Influence of neuroleptic drugs and apomorphine on dopamine-sensitive adenylate cyclase of retina.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Cattle; Chlorpromazine; Cyclic AMP; Dopamine; Enzyme Activation; Ergotamine; Fluphenazine; Haloperidol; Phentolamine; Phosphorus Isotopes; Propranolol; Retina; Tranquilizing Agents | 1973 |
Adenosine 3',5'-monophosphate content in rat caudate nucleus: demonstration of dopaminergic and adrenergic receptors.
Topics: Animals; Apomorphine; Biological Transport; Caudate Nucleus; Cocaine; Cyclic AMP; Dopamine; Fluphenazine; Isoproterenol; Norepinephrine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Drug | 1974 |
[Neuroleptic therapy of schizophrenia from pharmacological viewpoint].
Topics: Animals; Apomorphine; Arousal; Caudate Nucleus; Chlorpromazine; Chlorprothixene; Electroencephalography; Fluphenazine; Haloperidol; Humans; Methotrimeprazine; Perphenazine; Phenothiazines; Promazine; Rats; Reflex; Schizophrenia; Thioridazine; Tranquilizing Agents | 1969 |
Long-acting neuroleptics of perathiepin group: VUFB-9977 (oxyprothepin decanoate).
Topics: Animals; Antiemetics; Apomorphine; Delayed-Action Preparations; Dogs; Fluphenazine; Thiepins; Tranquilizing Agents; Vomiting | 1974 |
[Effect of neuroleptic agents in the chronic pharmacological experiment].
Topics: Animals; Apomorphine; Behavior, Animal; Catalepsy; Corpus Striatum; Dibenzoxazepines; Drug Tolerance; Electroencephalography; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Piperazines; Rats; Sleep; Tranquilizing Agents | 1974 |
Apomorphine provoked stereotype in the dog.
Topics: Amitriptyline; Animals; Anisoles; Apomorphine; Atropine; Behavior, Animal; Benzamides; Benztropine; Diazepam; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethylamines; Female; Fluphenazine; Haloperidol; Humans; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Piperazines; Receptors, Drug; Scopolamine; Stereotyped Behavior; Xanthenes | 1972 |
Noroxyclothepin decanoate (VUFB-9976) long-acting neuroleptic drug.
Topics: Animals; Apomorphine; Dibenzothiepins; Dogs; Fluphenazine; Piperazines; Tranquilizing Agents | 1973 |
Pharmacology of neuroleptics upon repeated administration.
Topics: Amphetamine; Animals; Apomorphine; Avoidance Learning; Catalepsy; Cross Reactions; Dose-Response Relationship, Drug; Drug Tolerance; Ethanol; Fluphenazine; Germ-Free Life; Haloperidol; Humans; Male; Methylphenidate; Mice; Mice, Inbred Strains; Pimozide; Piperazines; Stereotyped Behavior; Thioxanthenes; Time Factors; Tranquilizing Agents | 1974 |
Pharmacological effects of 1,3-dimethyl-5-aminoadamantane, a new adamantane derivative.
Topics: Amantadine; Animals; Apomorphine; Blood Pressure; Body Temperature; Brain Chemistry; Catalepsy; Chlorpromazine; Dextroamphetamine; Disulfides; Dopamine; Female; Fluphenazine; Haloperidol; Humans; Imidazoles; Male; Methyltyrosines; Motor Activity; Norepinephrine; Oxotremorine; Parasympatholytics; Rats; Reflex; Reserpine; Spiro Compounds; Stereotyped Behavior | 1974 |
Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and
Topics: Acepromazine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benperidol; Chlorpromazine; Chlorprothixene; Fluphenazine; Haloperidol; Male; Mastication; Methods; Motor Activity; Norepinephrine; Perphenazine; Phenothiazines; Prochlorperazine; Promazine; Rats; Thiazines; Thioridazine; Tranquilizing Agents; Trifluoperazine; Triflupromazine; Trimeprazine | 1967 |
[Pharmacologic studies of a prolonged action neuroleptic: fluphenazine enanthate].
Topics: Animals; Apomorphine; Behavior, Animal; Chloral Hydrate; Dextroamphetamine; Drug Synergism; Fluphenazine; Male; Mice; Pentobarbital; Prochlorperazine; Rats | 1966 |
Is there a "dopaminergic glial cell"?
Topics: Animals; Apomorphine; Brain; Cells, Cultured; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Fluphenazine; Neuroglia; Norepinephrine; Propranolol; Rats; Time Factors | 1984 |
Narcotic analgesics and stereotyped behaviour in mice.
Topics: Analgesics, Opioid; Animals; Apomorphine; Behavior; Dose-Response Relationship, Drug; Drug Interactions; Fluphenazine; Humans; Methylphenidate; Mice; Stereotyped Behavior | 1980 |
Dopamine autoreceptor and postsynaptic receptor blocking potency of neuroleptics.
Topics: Animals; Antipsychotic Agents; Apomorphine; Fluphenazine; Haloperidol; Male; Metoclopramide; Mice; Molindone; Motor Activity; Receptors, Dopamine; Sulpiride; Synapses | 1982 |
Effect of zotepine and various drugs on apomorphine- and methamphetamine-induced rotational behaviour in rats with unilateral lesions of the substantia nigra.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Apomorphine; Atropine; Behavior, Animal; Diazepam; Dibenzothiepins; Fluphenazine; Haloperidol; Male; Methamphetamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1983 |
Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity.
Topics: Animals; Antipsychotic Agents; Apomorphine; Brain Chemistry; Chlorpromazine; Fluphenazine; Haloperidol; Male; Peptides; Pimozide; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Non-opiate beta-endorphin fragments and dopamine--VI. Behavioural analysis of the interaction between gamma-type endorphins and dopaminergic systems in the nucleus accumbens of rats.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; beta-Endorphin; Bromocriptine; Dopamine; Endorphins; Ergolines; Fluphenazine; gamma-Endorphin; Haloperidol; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Sulpiride | 1984 |
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures | 1980 |
Effects of dobutamine on cyclic AMP accumulation induced by the stimulation of dopamine receptors in rabbit retina in vitro.
Topics: Animals; Apomorphine; Catecholamines; Cyclic AMP; Deoxyepinephrine; Dobutamine; Dopamine; Dose-Response Relationship, Drug; Fluphenazine; Rabbits; Receptors, Dopamine; Retina | 1980 |
Stimulation of a D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland decreases the responsiveness of the beta-adrenoceptor: biochemical mechanism.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Cell-Free System; Dose-Response Relationship, Drug; Fluphenazine; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Pituitary Gland; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Dopamine | 1981 |
Biochemical and physiological studies of the beta-adrenoceptor and the D-2 dopamine receptor in the intermediate lobe of the rat pituitary gland: a review.
Topics: Animals; Apomorphine; Catecholamines; Cyclic AMP; Fluphenazine; Guanosine Triphosphate; Isoproterenol; Melanocyte-Stimulating Hormones; Pituitary Gland; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2 | 1982 |
The behavioral and biochemical effects of lithium on dopaminergic agonist-induced supersensitivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Chemistry; Dopamine; Fluphenazine; Homovanillic Acid; Humans; Lithium; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors | 1984 |
Effect of a sulfonium analog of dopamine on the depolarization-induced release of [3H]acetylcholine from mouse striatal slices.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Apomorphine; Corpus Striatum; Dopamine; Fluphenazine; In Vitro Techniques; Male; Methyltyrosines; Mice; Potassium; Receptors, Dopamine; Reserpine | 1984 |
Enkephalin content in rat striatum during prolonged treatment with fluphenazine.
Topics: Animals; Apomorphine; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Fluphenazine; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Dopamine | 1984 |
Neuroleptic-induced dopamine hyposensitivity.
Topics: Animals; Apomorphine; Dopamine; Drug Interactions; Fluphenazine; Humans; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Thioridazine | 1984 |
Lack of potency of metoclopramide's metabolites in various dopaminergic models.
Topics: Animals; Apomorphine; Dopamine; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Metoclopramide; Prolactin; Rats; Rats, Inbred Strains; Spiperone; Stereotyped Behavior; Tetrahydronaphthalenes | 1983 |
Direct evidence for involvement of dopaminergic inhibition and cholinergic activation in yawning.
Topics: Animals; Apomorphine; Behavior, Animal; Dopamine Antagonists; Fluphenazine; Humans; Male; Parasympathetic Nervous System; Physostigmine; Pilocarpine; Rats; Reflex; Reserpine; Scopolamine; Stereotyped Behavior | 1980 |
Use of the intracerebral injection technique to elucidate mechanisms of apomorphine climbing and its antagonism in the mouse.
Topics: Animals; Apomorphine; Brain; Dose-Response Relationship, Drug; Fluphenazine; Humans; Hydroxydopamines; Injections; Male; Mice; Stereotyped Behavior; Sulpiride | 1981 |
[3H]spiroperidol identifies a D-2 dopamine receptor inhibiting adenylate cyclase activity in the intermediate lobe of the rat pituitary gland.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Binding, Competitive; Butyrophenones; Cholera Toxin; Fluphenazine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Male; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Sulpiride | 1982 |
Effects of haloperidol and apomorphine on catecholamine metabolism in brain slices. Reserpine-like effects of haloperidol.
Topics: Animals; Apomorphine; Brain Chemistry; Catecholamines; Chlorpromazine; Dopamine; Fluphenazine; Haloperidol; Male; Mice; Nerve Tissue Proteins; Reserpine | 1982 |
Tolerance to fluphenazine and supersensitivity to apomorphine in central dopaminergic systems after chronic fluphenazine decanoate treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Tolerance; Fluphenazine; Haloperidol; Homovanillic Acid; Humans; Male; Olfactory Bulb; Rats; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors | 1980 |
Emergence of apomorphine-induced 'vacuous chewing' during 6 months continuous treatment with fluphenazine decanoate.
Topics: Animals; Apomorphine; Fluphenazine; Humans; Male; Rats; Stereotyped Behavior; Time Factors | 1980 |
Striatal muscarinic receptors: regulation by dopaminergic agonists.
Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Fluphenazine; In Vitro Techniques; Isoproterenol; Male; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1981 |
Effect of psychoytopic drugs on high affinity choline uptake by excised tissue of rat nucleus caudatus.
Topics: Animals; Apomorphine; Caudate Nucleus; Choline; Fluphenazine; Haloperidol; Male; Rats; Receptors, Dopamine | 1980 |
Possible genetic factors underlying the pathophysiology of tardive dyskinesia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiparkinson Agents; Apomorphine; Cyclic AMP; Dyskinesia, Drug-Induced; Female; Fluphenazine; In Vitro Techniques; Male; Neostriatum; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1994 |
Altered spontaneous behavior and sensitivity to apomorphine in rats following pretreatment with S(+)-aporphines or fluphenazine.
Topics: Animals; Apomorphine; Aporphines; Behavior, Animal; Dopamine Antagonists; Fluphenazine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1993 |
Effects of dopamine agonists on Cebus apella monkeys with previous long-term exposure to fluphenazine.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Cebus; Dopamine Agonists; Dopamine Antagonists; Female; Fluphenazine; Growth Hormone; Male; Motor Activity; Prolactin; Stereotyped Behavior | 1997 |
Long-term effects of S(+)N-n-propylnorapomorphine compared with typical and atypical antipsychotics: differential increases of cerebrocortical D2-like and striatolimbic D4-like dopamine receptors.
Topics: Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Cell Line; Cerebral Cortex; Clozapine; Dopamine Agonists; Drug Design; Fluphenazine; Limbic System; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D4 | 1997 |
D2 dopamine antisense RNA expression vector, unlike haloperidol, produces long-term inhibition of D2 dopamine-mediated behaviors without causing Up-regulation of D2 dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Catalepsy; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Tolerance; Fluphenazine; Genetic Vectors; Grooming; Haloperidol; Male; Mice; Quinpirole; Receptors, Dopamine D2; RNA, Antisense; Stereotyped Behavior; Up-Regulation | 1998 |
Potent anti-apomorphine action of fluphenazine in pigeons.
Topics: Animals; Apomorphine; Columbidae; Fluphenazine; Humans; Tranquilizing Agents | 1962 |
Circadian-dependent effect of melatonin on dopaminergic D2 antagonist-induced hypokinesia and agonist-induced stereotypies in rats.
Topics: Animals; Apomorphine; Circadian Rhythm; Darkness; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Fluphenazine; Hypokinesia; Light; Male; Melatonin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Stereotyped Behavior | 2004 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |