Page last updated: 2024-08-17

apomorphine and benztropine

apomorphine has been researched along with benztropine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199028 (93.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dunstan, R; Jackson, DM1
Erzin-Waters, C; Muller, P; Seeman, P1
Dawes, P; Redfern, PH1
Carroll, BJ; Curtis, GC; Kokmen, E1
Heffner, TG; Stricker, EM; Zigmond, MJ1
Cheney, DL; Costa, E; Racagni, G; Trabucchi, M1
Braestrup, C; Scheel-Krüger, J1
De la Vega, CE; Friesen, HG; Lal, S; Martin, JB1
Barnett, A; Goldstein, J1
Buckett, WR; Shaw, JS1
Barnett, A; Goldstein, JM; Malick, JB1
Dandiya, PC; Kulkarni, SK1
Davis, JM; Smith, RC1
Carvey, PM; Goetz, CG; Hitri, A; Klawans, HL; Tanner, CM1
Chase, TN1
Benesová, O1
Nymark, M1
Barnett, A; Fiore, JW1
Lal, H; Puri, SK; Reddy, C1
Cashin, CH; Sutton, S1
Lahti, RA; Losey, EG1
Cubeddu, LX; Hoffmann, IS; James, MK1
Ackman, D; Etienne, P; Kiely, ME; Lal, S; Thavundayil, JX1
Cubeddu, LX; Hoffmann, IS1
Carey, RJ; De Veaugh-Geiss, J; Devanand, DP1
Cubeddu, LX; Hoffman, IS1
Spaan, SJ; Westerink, BH1

Reviews

3 review(s) available for apomorphine and benztropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopamine; Drug-Related Side Effects and Adverse Reactions; Extrapyramidal Tracts; Haloperidol; Humans; Methyltyrosines; Movement Disorders; Phenothiazines; Phenylacetates; Probenecid; Reserpine; Synaptic Transmission; Tetrabenazine; Tranquilizing Agents; Trihexyphenidyl

1972
[Review of current pharmacotherapy of Parkinsonism. Comprehensive review].
    Ceskoslovenska neurologie, 1973, Volume: 36, Issue:3

    Topics: 5-Hydroxytryptophan; Amantadine; Anticonvulsants; Apomorphine; Benztropine; Carboxy-Lyases; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Humans; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyphenidyl

1973

Trials

2 trial(s) available for apomorphine and benztropine

ArticleYear
Comparison of the effect of apomorphine and L-DOPA on serum growth hormone levels in normal men.
    Clinical endocrinology, 1975, Volume: 4, Issue:3

    Topics: Adult; Apomorphine; Benztropine; Blood Glucose; Growth Hormone; Humans; Hydrocortisone; Levodopa; Male; Nausea; Placebos; Radioimmunoassay

1975
Effect of apomorphine, a dopamine receptor agonist, on penile tumescence in normal subjects.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:4-6

    Topics: Adult; Apomorphine; Benztropine; Bromocriptine; Cholinergic Fibers; Dopamine; Drug Interactions; Humans; Levodopa; Male; Middle Aged; Penis

1984

Other Studies

25 other study(ies) available for apomorphine and benztropine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The demonstration of a change in adrenergic receptor sensitivity in the central nervous system of mice after withdrawal from long-term treatment with haloperidol.
    Psychopharmacology, 1976, Jul-09, Volume: 48, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Apomorphine; Benztropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Clonidine; Dextroamphetamine; Dopamine; Haloperidol; Male; Mice; Motor Activity; Pimozide; Receptors, Adrenergic; Receptors, Drug

1976
Catalepsy induced by morphine or haloperidol: effects of apomorphine and anticholinergic drugs.
    Canadian journal of physiology and pharmacology, 1976, Volume: 54, Issue:4

    Topics: Animals; Antipsychotic Agents; Apomorphine; Atropine; Benztropine; Catalepsy; Drug Interactions; Haloperidol; Humans; Male; Morphine; Rats; Scopolamine; Time Factors

1976
Changes in the conditiond avoidance behaviour of rats following the administration of drugs to the amygdala [proceedings].
    The Journal of pharmacy and pharmacology, 1976, Volume: 28 Suppl

    Topics: Amygdala; Animals; Apomorphine; Avoidance Learning; Benztropine; Conditioning, Psychological; Desipramine; Dextroamphetamine; Haloperidol; Male; Rats

1976
Paradoxical response to dopamine agonists in tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Apomorphine; Benztropine; Clozapine; Deanol; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Levodopa; Physostigmine; Receptors, Dopamine; Reserpine; Stimulation, Chemical; Thioridazine

1977
Effects of dopaminergic agonists and antagonists of feeding in intact and 6-hydroxydopamine-treated rats.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 201, Issue:2

    Topics: Animals; Apomorphine; Benztropine; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catecholamines; Cocaine; Dextroamphetamine; Dopamine; Dopamine Antagonists; Eating; Hydroxydopamines; Levodopa; Male; Methylphenidate; Methyltyrosines; Motor Activity; Rats; Spiperone; Telencephalon

1977
In vivo actions of clozapine and haloperidol on the turnover rate of acetylcholine in rat striatum.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:2

    Topics: Animals; Apomorphine; Benztropine; Clozapine; Corpus Striatum; Dibenzazepines; Dopamine; Drug Interactions; Humans; Kinetics; Male; Motor Activity; Oxotremorine; Rats; Receptors, Drug; Stereotyped Behavior; Trihexyphenidyl

1976
Methylphenidate-like effects of the new antidepressant drug nomifensine (HOE 984).
    European journal of pharmacology, 1976, Volume: 38, Issue:2

    Topics: Animals; Antidepressive Agents; Apomorphine; Benztropine; Cocaine; Corpus Striatum; Dextroamphetamine; Dopamine; Humans; Isoquinolines; Male; Methylphenidate; Rats; Reserpine; Stereotyped Behavior; Synaptosomes; Time Factors

1976
Head-turning induced by electrical stimulation of the caudate nucleus and its antagonism by anti-parkinson drugs.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:2

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Benztropine; Caudate Nucleus; Depression, Chemical; Electric Stimulation; Humans; Levodopa; Male; Rats; Stereotyped Behavior; Trihexyphenidyl

1975
Dopaminergic drugs antagonize the psychotomimetic effects of partial-agonist analgesics.
    Psychopharmacologia, 1975, Jun-19, Volume: 42, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior; Benztropine; Cyclazocine; Dopamine; Dose-Response Relationship, Drug; Humans; Levallorphan; Levodopa; Male; Motor Activity; Naloxone; Piribedil; Rats; Rats, Inbred Strains; Stereotyped Behavior

1975
The evaluation of anti-parkinson drugs on reserpine-induced rigidity in rats.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Carbidopa; Hindlimb; Levodopa; Male; Methamphetamine; Muscle Rigidity; Rats; Reserpine; Scopolamine; Time Factors; Trihexyphenidyl

1975
Influence of chemical stimulation of central dopaminergic system on the open field behaviour of rats.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1975, Volume: 8, Issue:1

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benztropine; Brain; Dopamine; Levodopa; Male; Rats; Stimulation, Chemical

1975
Behavioral supersensitivity to apomorphine and amphetamine after chronic high dose haloperidol treatment.
    Psychopharmacology communications, 1975, Volume: 1, Issue:3

    Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benztropine; Drug Interactions; Haloperidol; Humans; Male; Motor Activity; Rats; Stereotyped Behavior; Time Factors

1975
Concurrent treatment with benztropine and haloperidol attenuates development of behavioral hypersensitivity but not dopamine receptor proliferation.
    Life sciences, 1988, Volume: 42, Issue:22

    Topics: Animals; Apomorphine; Benztropine; Corpus Striatum; Dopamine; Haloperidol; Homovanillic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Tropanes

1988
Apomorphine provoked stereotype in the dog.
    Psychopharmacologia, 1972, Volume: 26, Issue:4

    Topics: Amitriptyline; Animals; Anisoles; Apomorphine; Atropine; Behavior, Animal; Benzamides; Benztropine; Diazepam; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethylamines; Female; Fluphenazine; Haloperidol; Humans; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Piperazines; Receptors, Drug; Scopolamine; Stereotyped Behavior; Xanthenes

1972
The effect of antiparkinson drugs on the liguomandibular reflex in cats.
    European journal of pharmacology, 1973, Volume: 21, Issue:2

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Cats; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Haloperidol; Lingual Nerve; Mandibular Nerve; Phenoxybenzamine; Receptors, Drug; Reflex

1973
Blockade of central dopaminergic receptors of morphine: effect of haloperidol, apomorphine or benztropine.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:2

    Topics: Animals; Antiparkinson Agents; Apomorphine; Benztropine; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Haloperidol; Humans; Kinetics; Male; Morphine; Rats; Receptors, Drug; Stereotyped Behavior; Tropanes

1973
The effect of anti-Parkinson drugs on catalepsy induced by -methyl-p-tyrosine in rats pretreated with intraventricular 6-hydroxydopamine.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Amantadine; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Benztropine; Brain Chemistry; Catalepsy; Dextroamphetamine; Dihydroxyphenylalanine; Humans; Hydroxydopamines; Methylphenidate; Methyltyrosines; Rats; Reserpine; Scopolamine

1973
Antagonism of the effects of chlorpromazine and morphine on dopamine metabolism by GABA.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 7, Issue:1

    Topics: Acetates; Aminobutyrates; Animals; Apomorphine; Benztropine; Chlorpromazine; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxylamines; Male; Methyltyrosines; Morphine; Rats

1974
Frequency-dependent effects of neuronal uptake inhibitors on the autoreceptor-mediated modulation of dopamine and acetylcholine release from the rabbit striatum.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Benztropine; Bupropion; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Drug Interactions; Electric Stimulation; Neurons; Nomifensine; Propiophenones; Rabbits; Sulpiride

1983
Frequency-dependent release of acetylcholine and dopamine from rabbit striatum: its modulation by dopaminergic receptors.
    Journal of neurochemistry, 1983, Volume: 41, Issue:1

    Topics: Acetylcholine; Animals; Apomorphine; Benztropine; Caudate Nucleus; Corpus Striatum; Dopamine; Electric Stimulation; Haloperidol; In Vitro Techniques; Putamen; Rabbits; Receptors, Dopamine; Sulpiride

1983
Differential liabilities of haloperidol and thioridazine for inducing apomorphine hypersensitivity.
    Biological psychiatry, 1982, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Benztropine; Corpus Striatum; Dose-Response Relationship, Drug; Haloperidol; Humans; Limbic System; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereotyped Behavior; Substance Withdrawal Syndrome; Thioridazine

1982
Presynaptic effects of tetrahydropapaveroline on striatal dopaminergic neurons.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:1

    Topics: Animals; Apomorphine; Benztropine; Bromocriptine; Caudate Nucleus; Dopamine; Female; Haloperidol; In Vitro Techniques; Male; Neurons; Papaverine; Putamen; Rabbits; Synapses; Tetrahydropapaveroline

1982
On the significance of endogenous 3-methoxytyramine for the effects of centrally acting drugs on dopamine release in the rat brain.
    Journal of neurochemistry, 1982, Volume: 38, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Butyrolactone; Animals; Apomorphine; Benztropine; Brain; Chlorpromazine; Dextroamphetamine; Dopamine; Female; Haloperidol; Homovanillic Acid; Kinetics; Morphine; Nomifensine; Oxotremorine; Rats; Rats, Inbred Strains; Reserpine

1982