Page last updated: 2024-08-17

apomorphine and baclofen

apomorphine has been researched along with baclofen in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199018 (54.55)18.7374
1990's4 (12.12)18.2507
2000's8 (24.24)29.6817
2010's3 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andén, NE1
Breese, GR; Mailman, RB; Mueller, RA1
Gianutsos, G; Moore, KE1
Friedle, NM; Moore, KE; Wuerthele, SM1
Demarest, KT; Moore, KE1
Costentin, J; Marcais, H; Protais, P1
Delini-Stula, A1
Kelly, PH; Moore, KE1
Agnati, L; Everitt, BJ; Fuxe, K; Hökfelt, T; Ljungdahl, A; Perez de la Mora, M1
Bond, A; Neal, H1
Höglund, U; Lindgren, S; Westerling, P1
Ito, T; Kadokawa, T; Miura, Y1
Boi, V; Calabresi, P; Gessa, GL; Mereu, G; Muntoni, F; Romani, F1
Aoki, H; Kamata, K; Kameyama, T1
Czuczwar, SJ; Kleinrok, Z; Kozicka, M1
Dahlström, S; Koulu, M; Lammintausta, R1
Argiolas, A; Fadda, F; Gessa, GL; Marcou, M; Melis, MR; Porceddu, ML1
Broxterman, HJ; Noach, EL; van Valkenburg, CF; Wijling, A1
Palermo-Neto, J; Sandoval, MR1
Farahvash, H; Zarrindast, MR1
Dalia, A; Narayanan, S; Uretsky, N; Wallace, L; Willins, D1
Cruijsen, PM; Dotman, CH; Jenks, BG; Roubos, EW1
Argiolas, A; Rosaria Melis, M; Spano, MS; Succu, S1
Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T1
Jang, CG; Kim, HS; Lee, MK; Oh, KW; Oh, SK; Seong, YH; Woo, SH; Yun, JS1
Argiolas, A; Melis, MR1
Aru, GN; Bortolato, M; Frau, R; Gessa, GL; Orrù, M1
Jenks, BG; Roubos, EW; Scheenen, WJ; Zhang, H1

Reviews

1 review(s) available for apomorphine and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

32 other study(ies) available for apomorphine and baclofen

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of gamma-hydroxybutyric acid, baclofen, aminooxyacetic acid, and apomorphine on dopamine turnover in corpus striatum and limbic system.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxybutyrates; Limbic System; Methyltyrosines; Rats; Substantia Nigra; Tyrosine 3-Monooxygenase

1977
The effect of drugs which alter GABA-ergic function on cerebellar guanosine-3',5'-monophosphate content.
    Life sciences, 1978, Aug-14, Volume: 23, Issue:6

    Topics: Animals; Apomorphine; Baclofen; Cerebellum; Cyclic GMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Rats; Time Factors

1978
Increase in mouse brain dopamine content by baclofen: effects of apomorphine and neuroleptics.
    Psychopharmacology, 1977, May-09, Volume: 52, Issue:3

    Topics: Aminobutyrates; Animals; Apomorphine; Baclofen; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Mice; Pimozide

1977
Effects of intranigral administration of dopamine agonists and antagonists and baclofen on concentrations of dopac and dopamine in the striatum and substantia nigra of the rat.
    Journal of neural transmission, 1979, Volume: 45, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aminobutyrates; Animals; Apomorphine; Baclofen; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Phenylacetates; Rats; Substantia Nigra

1979
Comparison of dopamine synthesis regulation in the terminals of nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophyseal neurons.
    Journal of neural transmission, 1979, Volume: 46, Issue:4

    Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Benzyl Alcohols; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hypothalamo-Hypophyseal System; Male; Median Eminence; Nialamide; Olfactory Bulb; Piribedil; Pituitary Gland, Posterior; Rats; Reserpine

1979
Hypersensitivity of the climbing behaviour response to apomorphine induced by a short depression of dopaminergic neurone activity.
    Neuropharmacology, 1979, Volume: 18, Issue:11

    Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Cycloheximide; Dopamine; Hydroxybutyrates; Male; Mice; Motor Activity; Neurons; Sodium Oxybate

1979
Baclofen-induced modification of conditioned discriminative avoidance behaviour and contraversive turning in the rat.
    European journal of pharmacology, 1977, Dec-01, Volume: 46, Issue:3

    Topics: Aminobutyrates; Animals; Apomorphine; Avoidance Learning; Baclofen; Behavior; Discrimination, Psychological; Humans; Hydroxydopamines; Male; Physostigmine; Rats; Stereotyped Behavior; Time Factors

1977
Dopamine concentrations in the rat brain following injections into the substantia nigra of baclofen, gamma-aminobutyric acid, gamma-hydroxybutyric acid, apomorphine and amphetamine.
    Neuropharmacology, 1978, Volume: 17, Issue:3

    Topics: Animals; Apomorphine; Baclofen; Behavior, Animal; Brain Chemistry; Dextroamphetamine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections; Male; Rats; Substantia Nigra; Time Factors

1978
Action of beta(4-chlorphenyl)GABA, gamma-hydroxybutyrolactone, and apomorphine on central dopamine neurons.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: 4-Butyrolactone; Aminobutyrates; Animals; Apomorphine; Baclofen; Brain; Castration; Dopamine; Estrogens; Female; Furans; Neurons; Piribedil; Rats; Receptors, Dopamine; Sexual Behavior, Animal; Time Factors

1977
Quantitative electrocortical changes in the rat induced by phencyclidine and other stimulants.
    Neuropharmacology, 1985, Volume: 24, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Dioxolanes; Electroencephalography; Isoquinolines; Isoxazoles; Male; Muscimol; Phencyclidine; Rats; Rats, Inbred Strains

1985
Dopamine mediated behavior and GABA influence.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:3

    Topics: Animals; Apomorphine; Baclofen; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains

1988
Effects of intraseptally injected dopamine and noradrenaline on hippocampal synchronized theta wave activity in rats.
    Japanese journal of pharmacology, 1987, Volume: 44, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Brain; Dopamine; Electroencephalography; Haloperidol; Hippocampus; Injections; Male; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Theta Rhythm

1987
Responsiveness to 'autoreceptor' doses of apomorphine inversely correlated with the firing rate of dopaminergic A9 neurons: action of baclofen.
    Neuroscience letters, 1986, Apr-11, Volume: 65, Issue:2

    Topics: Animals; Apomorphine; Baclofen; Dopamine; Electrophysiology; Male; Neural Inhibition; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra

1986
Involvement of the dopaminergic system in the regulation of the caudate spindle in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 256, Issue:2

    Topics: Action Potentials; Animals; Antipsychotic Agents; Apomorphine; Baclofen; Caudate Nucleus; Dopamine; Drug Interactions; Male; Methysergide; Physostigmine; Picrotoxin; Rats; Rats, Inbred Strains; Time Factors

1982
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures

1980
Effects of some gamma-aminobutyric acid (GABA)-ergic drugs on the dopaminergic control of human growth hormone secretion.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:1

    Topics: Adult; Apomorphine; Baclofen; Diazepam; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Male; Valproic Acid

1980
Delayed inhibition of dopamine synthesis by gamma-butyrolactone and baclofen: dopamine autoreceptor supersensitivity?
    European journal of pharmacology, 1982, Nov-05, Volume: 85, Issue:1

    Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Furans; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Time Factors

1982
Cross-tolerance of dopamine metabolism to baclofen, gamma-butyrolactone and HA-966 in the striatum and olfactory tubercle of the rat.
    Life sciences, 1981, Mar-02, Volume: 28, Issue:9

    Topics: 4-Butyrolactone; Animals; Apomorphine; Baclofen; Central Nervous System Depressants; Corpus Striatum; Dopamine; Drug Tolerance; Male; Olfactory Bulb; Pyrrolidinones; Rats

1981
Effect of manipulation of the GABA system on dopamine-related behaviors.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1995, Volume: 28, Issue:1

    Topics: 3-Mercaptopropionic Acid; Animals; Apomorphine; Baclofen; Catalepsy; Dopamine Agonists; GABA Agents; Haloperidol; Male; Mice; Motor Activity; Picrotoxin; Rats; Rats, Wistar; Stereotyped Behavior

1995
Effects of GABA-ergic drugs on penile erection induced by apomorphine in rats.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Animals; Apomorphine; Baclofen; Dopamine; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Muscimol; Penile Erection; Rats

1994
Role of dopaminergic mechanisms in the stimulatory effects of MK-801 injected into the ventral tegmental area and the nucleus accumbens.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Apomorphine; Baclofen; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; GABA Agonists; Histocytochemistry; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reserpine; Salicylamides; Stimulation, Chemical; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

1996
Differential action of secreto-inhibitors on proopiomelanocortin biosynthesis in the intermediate pituitary of Xenopus laevis.
    Endocrinology, 1996, Volume: 137, Issue:11

    Topics: alpha-MSH; Analysis of Variance; Animals; Apomorphine; Baclofen; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; In Vitro Techniques; Isonicotinic Acids; Kinetics; Neuropeptide Y; Pituitary Gland; Pro-Opiomelanocortin; Receptors, Dopamine D2; Xenopus laevis

1996
Activation of gamma-aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces apomorphine-, N-methyl-D-aspartic acid- and oxytocin-induced penile erection and yawning in male rats.
    Neuroscience letters, 2000, Mar-10, Volume: 281, Issue:2-3

    Topics: Animals; Apomorphine; Baclofen; Dopamine Agonists; Excitatory Amino Acid Agonists; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Male; Muscimol; N-Methylaspartate; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Yawning

2000
Involvement of GABAergic neurotransmission in the neurobiology of the apomorphine-induced aggressive behavior paradigm, a model of psychotic behavior in rats.
    Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8

    Topics: Aggression; Animals; Apomorphine; Baclofen; Behavior, Animal; Disease Models, Animal; GABA Agonists; Isoxazoles; Male; Neurotransmitter Agents; Psychotic Disorders; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission

2000
Inhibition of baclofen on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity.
    Pharmacological research, 2001, Volume: 43, Issue:4

    Topics: Animals; Apomorphine; Baclofen; Drug Tolerance; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred ICR; Monitoring, Physiologic; Morphine; Motor Activity; Receptors, Dopamine; Synapses; Time Factors

2001
Reduction of drug-induced yawning and penile erection and of noncontact erections in male rats by the activation of GABAA receptors in the paraventricular nucleus: involvement of nitric oxide.
    The European journal of neuroscience, 2002, Volume: 15, Issue:5

    Topics: Animals; Apomorphine; Baclofen; Bicuculline; Copulation; Extracellular Space; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; N-Methylaspartate; Neural Inhibition; Nitrates; Nitric Oxide; Nitrites; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Yawning

2002
Baclofen reverses the reduction in prepulse inhibition of the acoustic startle response induced by dizocilpine, but not by apomorphine.
    Psychopharmacology, 2004, Volume: 171, Issue:3

    Topics: Acoustic Stimulation; Animals; Apomorphine; Baclofen; Dizocilpine Maleate; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle

2004
Receptors for neuropeptide Y, gamma-aminobutyric acid and dopamine differentially regulate Ca2+ currents in Xenopus melanotrope cells via the G(i) protein beta/gamma-subunit.
    General and comparative endocrinology, 2006, Jan-15, Volume: 145, Issue:2

    Topics: Animals; Apomorphine; Baclofen; Calcium; Calcium Channels; Cells, Cultured; Dopamine Agonists; Electric Conductivity; GABA Agonists; GABA-B Receptor Agonists; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Melanocyte-Stimulating Hormones; Neuropeptide Y; Patch-Clamp Techniques; Pituitary Gland; Receptors, Dopamine D2; Receptors, G-Protein-Coupled; Receptors, GABA-B; Receptors, Neuropeptide Y; Xenopus laevis

2006