apomorphine has been researched along with ascorbic acid in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (47.37) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 2 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Crow, TJ; Waddington, JL | 1 |
| Middaugh, LD; Thomas, TN; Tolbert, LC; Zemp, JW | 1 |
| Staib, AH; Westermann, KH | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, E; Miele, M | 3 |
| Abraini, JH; Fechtali, T; Rostain, JC | 1 |
| Bardo, MT; Pierce, RC; Rebec, GV; Rowlett, JK | 1 |
| Braun, T | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Miele, E; Miele, M | 1 |
| Desole, MS; Enrico, P; Miele, E; Miele, M | 1 |
| Kiyatkin, EA | 1 |
| Crisp, T; Henderson, LJ; Trulson, ME | 1 |
| Kruk, ZL; Millar, J; Stamford, JA | 1 |
| Shin, SH; Stirling, R | 1 |
| Lyerly, MA; Nashold, BS; Ovelmen-Levitt, J; Rossitch, E | 1 |
| Reyneke, L; Russell, VA; Taljaard, JJ | 1 |
| Dorris, RL | 1 |
| Cabbat, FS; Heikkila, RE; Manzino, L | 1 |
| Goldman, CP; Riffee, WH; Wilcox, RE; Young, RK | 1 |
| Fishman, RH; Mittleman, L; Yanai, J | 1 |
| Arana, GW; Baldessarini, RJ; Kula, NS | 1 |
| Grecksch, G; Jork, R; Matthies, H | 1 |
| Combs, HF; Corby, DG; Decker, WJ | 1 |
| Humphrey, DW; Riffee, WH; Smith, RV; Wilcox, RE | 1 |
| Kayaalp, SO; Neff, NH | 1 |
| De Natale, G; Desole, MS; Enrico, P; Esposito, G; Fresu, L; Miele, M; Migheli, R | 1 |
| Danhof, M; Neef, C; Roon, KI; Roos, RA; van Laar, T | 1 |
| Sam, EE; Verbeke, N | 1 |
| Fuxe, K; Järv, J; Lepiku, M; Rinken, A | 1 |
| Andreazza, AC; Salvador, M; Soares, DG | 1 |
| Chang, MY; Chung, HY; Kim, JY; Kim, YC; Koh, HC; Lee, JY; Lee, SH; Lee, YS; McKay, R; Son, H; Studer, L | 1 |
| Borman, JB; Chevion, M; Khaliulin, I; Schwalb, H | 1 |
| Feldon, J; Russig, H; Yee, BK | 1 |
| Ingram, WM; Priston, MJ; Sewell, GJ | 1 |
| Deshpande, C; Dhir, A; Kulkarni, SK | 1 |
2 review(s) available for apomorphine and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Selective pharmacological changes of regional ascorbic acid metabolism in the brain].
Topics: Analysis of Variance; Animals; Apomorphine; Ascorbic Acid; Brain; Dextroamphetamine; Haloperidol; Liver; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
1 trial(s) available for apomorphine and ascorbic acid
| Article | Year |
|---|---|
A new sublingual formulation of apomorphine in the treatment of patients with Parkinson's disease.
Topics: Administration, Sublingual; Aged; Antiparkinson Agents; Apomorphine; Ascorbic Acid; Biological Availability; Cross-Over Studies; Female; Humans; Injections, Subcutaneous; Male; Metabolic Clearance Rate; Middle Aged; Neurologic Examination; Parkinson Disease; Treatment Outcome | 1996 |
35 other study(ies) available for apomorphine and ascorbic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Drug-induced rotational behaviour following unilateral intracerebral injection of saline-ascorbate solution: neurotoxicity of ascorbic acid and monoamine-independent circling.
Topics: 5-Methoxytryptamine; 5,7-Dihydroxytryptamine; Animals; Apomorphine; Ascorbic Acid; Behavior; Cerebral Cortex; Corpus Striatum; Dihydroxytryptamines; Dopamine; gamma-Aminobutyric Acid; Humans; Hydroxydopamines; Male; Medial Forebrain Bundle; Motor Activity; Norepinephrine; Rats; Serotonin; Sodium Chloride; Stereotyped Behavior; Tryptamines | 1979 |
Effect of ascorbic acid on neurochemical, behavioral, and physiological systems mediated by catecholamines.
Topics: Adenylyl Cyclases; Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Body Temperature; Brain Chemistry; Catecholamines; Male; Mice; Mice, Inbred C57BL; Time Factors | 1979 |
[Nigrostriatally induced motor reactions in the rat. I. Rotational behavior and posture asymetry after intracerebral injection of apomorphine and dopamine].
Topics: Animals; Apomorphine; Ascorbic Acid; Brain; Caudate Nucleus; Dopamine; Female; Haloperidol; Hydroxydopamines; Injections; Movement Disorders; Posture; Rats; Receptors, Dopamine | 1976 |
Effects of cortical ablation on apomorphine- and scopolamine-induced changes in dopamine turnover and ascorbic acid catabolism in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Ascorbic Acid; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Male; Rats; Rats, Inbred Strains; Scopolamine | 1992 |
Pressure reversed extracellular striatal dopamine decrease produced by D1 receptor agonist SKF 38393, and D2 receptor agonist LY 171555, but failed to change the effect of the activation of both D1 and D2 receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Apomorphine; Ascorbic Acid; Cerebral Ventricles; Corpus Striatum; Dopamine; Dopamine Agents; Electroencephalography; Ergolines; Homovanillic Acid; Injections, Intraventricular; Kinetics; Male; Methyltyrosines; Pargyline; Pressure; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synapses; Uric Acid | 1992 |
Chronic ascorbate potentiates the effects of chronic haloperidol on behavioral supersensitivity but not D2 dopamine receptor binding.
Topics: Amphetamines; Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Drug Synergism; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Up-Regulation | 1991 |
Further investigations into the relationship between the dopaminergic system, ascorbic acid and uric acid in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Ascorbic Acid; Body Temperature; Corpus Striatum; Dehydroascorbic Acid; Dopamine; Male; Motor Activity; Oxidation-Reduction; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine; Stereotyped Behavior; Uric Acid | 1991 |
Investigations into the relationship between the dopaminergic system and ascorbic acid in rat striatum.
Topics: Animals; Apomorphine; Ascorbic Acid; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1991 |
Inhibition of the soluble form of testis adenylate cyclase by catechol estrogens and other catechols.
Topics: Adenylyl Cyclase Inhibitors; Animals; Apomorphine; Ascorbic Acid; Catechols; Dopamine; Dopamine Agents; Estrogens, Catechol; Isoproterenol; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Testis | 1990 |
Analysis of the mechanism of d-amphetamine-and apomorphine-induced changes of ascorbic acid catabolism in discrete brain areas of the rat.
Topics: Animals; Apomorphine; Ascorbic Acid; Brain Chemistry; Corpus Striatum; Dehydroascorbic Acid; Dextroamphetamine; Haloperidol; Hypothalamus; Male; Rats; Rats, Inbred Strains | 1991 |
Dopaminergic involvement in nociceptive sensitivity/behavioral reactivity regulation during aversive states of different nature in the rat.
Topics: Acetates; Acetic Acid; Animals; Apomorphine; Ascorbic Acid; Avoidance Learning; Behavior, Animal; Dopamine; Electromyography; Female; Haloperidol; Nociceptors; Pain; Rats; Synaptic Transmission | 1989 |
Ascorbic acid antagonizes the behavioural effects of LSD in cats.
Topics: Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Cats; Lysergic Acid Diethylamide; Methoxydimethyltryptamines | 1985 |
Ascorbic acid does not modulate stimulated dopamine release: in vivo voltammetric data in the rat.
Topics: Animals; Apomorphine; Ascorbic Acid; Corpus Striatum; Dopamine; Electric Stimulation; In Vitro Techniques; Medial Forebrain Bundle; Metoclopramide; Neural Pathways; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission | 1985 |
Ascorbic acid potentiates the inhibitory effect of dopamine on prolactin release in primary cultured rat pituitary cells.
Topics: Animals; Apomorphine; Ascorbic Acid; Cells, Cultured; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Male; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains | 1988 |
The deafferentation syndrome in the rat: effects of intraventricular apomorphine.
Topics: Afferent Pathways; Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Denervation; Female; Forelimb; Hindlimb; Nervous System Diseases; Pain; Rats; Rats, Inbred Strains; Syndrome | 1988 |
The modulatory effect of neurotensin on [3H]dopamine release from rat nucleus accumbens slices is enhanced after chronic desipramine treatment.
Topics: Animals; Apomorphine; Ascorbic Acid; Desipramine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Male; Neurotensin; Nomifensine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Septal Nuclei; Time Factors; Tritium | 1987 |
Ascorbic acid reduces accumulation of [3H]spiperone in mouse striatum in vivo.
Topics: Animals; Apomorphine; Ascorbic Acid; Cerebellum; Corpus Striatum; Depression, Chemical; Dopamine Antagonists; Drug Synergism; Haloperidol; Mice; Receptors, Dopamine; Spiperone | 1987 |
Studies on the stability of 3H-dopamine, 3H-apomorphine and 3H-ADTN: effects of sodium ascorbate and EDTA.
Topics: Animals; Apomorphine; Ascorbic Acid; Brain; Buffers; Dopamine; Drug Stability; Edetic Acid; Male; Membranes; Naphthalenes; Rats; Temperature; Tetrahydronaphthalenes; Time Factors | 1985 |
Effects of ascorbate on a dopaminergic response: apomorphine-induced modification of pentylenetetrazol-induced seizures in mice.
Topics: Animals; Apomorphine; Ascorbic Acid; Dose-Response Relationship, Drug; Male; Mice; Pentylenetetrazole; Receptors, Dopamine; Seizures; Time Factors | 1984 |
Ascorbic acid effect on ethanol sensitivity via possible dopaminergic mediation.
Topics: Animals; Apomorphine; Ascorbic Acid; Brain; Dose-Response Relationship, Drug; Ethanol; Female; Male; Mice; Mice, Inbred Strains; Motor Activity; Receptors, Dopamine; Sleep Stages | 1984 |
Differential effects of ascorbate and EDTA on high-affinity binding of 3H-apomorphine and 3H-ADTN to calf caudate membranes.
Topics: Animals; Apomorphine; Ascorbic Acid; Cattle; Caudate Nucleus; Dose-Response Relationship, Drug; Edetic Acid; Receptors, Dopamine; Synaptic Membranes; Tetrahydronaphthalenes | 1982 |
Apomorphine and glycoprotein synthesis during consolidation.
Topics: Animals; Apomorphine; Ascorbic Acid; Discrimination Learning; Fucose; Glycoproteins; Hippocampus; Learning; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains | 1982 |
A stable parenteral solution of apomorphine.
Topics: Antioxidants; Apomorphine; Ascorbic Acid; Infusions, Parenteral; Solutions; Sterilization; Time Factors | 1981 |
Stability of apomorphine in solutions containing ascorbic acid and bisulfite and effects of antioxidants on apomorphine-induced cage climbing and hypothermia in mice.
Topics: Animals; Antioxidants; Apomorphine; Ascorbic Acid; Body Temperature; Drug Interactions; Drug Stability; Mice; Motor Activity; Sulfites | 1980 |
Differentiation by ascorbic acid of dopamine agonist and antagonist binding sites in striatum.
Topics: Animals; Apomorphine; Ascorbic Acid; Corpus Striatum; Dopamine Antagonists; Haloperidol; Male; Naphthols; Oxidation-Reduction; Rats; Receptors, Dopamine; Spiperone; Tetrahydronaphthalenes | 1980 |
Cortical ablation and drug-induced changes in striatal ascorbic acid oxidation and behavior in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Cerebral Cortex; Dehydroascorbic Acid; Dopamine; Glutamic Acid; Male; Motor Activity; Neostriatum; Oxidation-Reduction; Rats; Rats, Wistar; Scopolamine; Stereotyped Behavior; Synaptosomes | 1995 |
Free radical scavenging properties of apomorphine enantiomers and dopamine: possible implication in their mechanism of action in parkinsonism.
Topics: Apomorphine; Ascorbic Acid; Corpus Striatum; Dopamine; Free Radicals; Oxidative Stress; Parkinson Disease; Peroxides; Spectrophotometry | 1995 |
Reversible and irreversible components of [(3)H]-N-propylnorapomorphine interaction with rat striatal membranes.
Topics: Animals; Antioxidants; Apomorphine; Ascorbic Acid; Binding Sites; Binding, Competitive; Cell Membrane; Dithiothreitol; Dopamine; Kinetics; Neostriatum; Oxidation-Reduction; Radioactive Tracers; Rats; Receptors, Dopamine; Tritium | 2002 |
Sequestering ability of butylated hydroxytoluene, propyl gallate, resveratrol, and vitamins C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems.
Topics: Antioxidants; Apomorphine; Ascorbic Acid; Benzothiazoles; beta Carotene; Biphenyl Compounds; Butylated Hydroxytoluene; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Paraquat; Picrates; Propyl Gallate; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Sulfonic Acids; Vitamin E | 2003 |
Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression.
Topics: Animals; Antigens, Differentiation; Apomorphine; Ascorbic Acid; Astrocytes; Cell Differentiation; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Dopamine; Gene Expression; Gestational Age; Graft Survival; Male; Mesencephalon; Motor Activity; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Retroviridae; Stem Cell Transplantation; Stem Cells; Transcription Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase | 2003 |
Cardioprotective and antioxidant effects of apomorphine.
Topics: Animals; Antioxidants; Apomorphine; Ascorbic Acid; Copper; Coronary Circulation; Dopamine Agonists; Dose-Response Relationship, Drug; Free Radicals; Heart; Ions; Iron; Male; Models, Chemical; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Oxygen; Rats; Rats, Sprague-Dawley; Spectrophotometry; Time Factors | 2003 |
Apomorphine-induced prepulse inhibition disruption is associated with a paradoxical enhancement of prepulse stimulus reactivity.
Topics: Acoustic Stimulation; Animals; Apomorphine; Ascorbic Acid; Behavior, Animal; Dextroamphetamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Radiation; Drug Interactions; Haloperidol; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Reflex, Startle | 2004 |
Improved assay for R(-)-apomorphine with application to clinical pharmacokinetic studies in Parkinson's disease.
Topics: Apomorphine; Ascorbic Acid; Chromatography, High Pressure Liquid; Drug Stability; Freezing; Humans; Parkinson Disease; Reproducibility of Results; Sensitivity and Specificity | 2006 |
Antagonistic activity of ascorbic acid (vitamin C) on dopaminergic modulation: apomorphine-induced stereotypic behavior in mice.
Topics: Animals; Antioxidants; Antipsychotic Agents; Apomorphine; Ascorbic Acid; Azepines; Benzazepines; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Combinations; Haloperidol; Male; Mice; Reserpine; Stereotyped Behavior; Sulpiride | 2006 |