Page last updated: 2024-08-17

apomorphine and amitriptyline

apomorphine has been researched along with amitriptyline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199020 (68.97)18.7374
1990's1 (3.45)18.2507
2000's4 (13.79)29.6817
2010's4 (13.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Argiolas, A; Fadda, F; Gessa, GL; Klimek, V; Serra, G1
Delini-Stula, A; Vassout, A1
Cuparencu, B; Sandor, V1
Lippman, W; Pugsley, TA1
Fujiwara, M; Inoue, K; Ueki, S1
Chen, PO; Endo, T; Matsuda, H; Nishimori, T; Sato, K; Shibuya, T1
Fujiwara, M; Ibii, N; Inoue, K; Kataoka, Y; Ueki, S1
Narkevich, VB; Prikhozhan, AV; Raevskiĭ, KS1
Chandra, O; Dhawan, KN; Gupta, GP; Saxena, RC1
Nymark, M1
Soyka, D1
Brand, U; Menge, HG1
Dyntarová, H; Votava, Z1
Senault, B1
Pedersen, V1
Costain, DW; Cowen, PJ; Gelder, MG; Grahame-Smith, DG1
Maj, J; Rogóz, Z; Skuza, G; Sowińska, H1
Braddock, LE; Cowen, PJ; Gosden, B1
Wassermann, K1
Antelman, SM; Chiodo, LA1

Reviews

1 review(s) available for apomorphine and amitriptyline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for apomorphine and amitriptyline

ArticleYear
[The effect of psychopharmacological drugs and other central nervous system effecting drugs on experimental nystagmus].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1968, Volume: 36, Issue:9

    Topics: Amitriptyline; Apomorphine; Aporphines; Barbiturates; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Diazepam; Dimenhydrinate; Eye Movements; Fluphenazine; Haloperidol; Humans; Imipramine; Schizophrenia; Thioridazine; Triflupromazine

1968
Electroconvulsive therapy and the brain: evidence for increased dopamine-mediated responses.
    Lancet (London, England), 1982, Aug-21, Volume: 2, Issue:8295

    Topics: Amitriptyline; Antidepressive Agents; Apomorphine; Brain; Depression; Dopamine; Electroconvulsive Therapy; Female; Growth Hormone; Humans; Male

1982

Other Studies

26 other study(ies) available for apomorphine and amitriptyline

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Chronic treatment with antidepressants prevents the inhibitory effect of small doses of apomorphine on dopamine synthesis and motor activity.
    Life sciences, 1979, Jul-30, Volume: 25, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Caudate Nucleus; Chlorpromazine; Dopamine; Imipramine; Male; Mianserin; Motor Activity; Rats; Receptors, Dopamine

1979
Modulation of dopamine-mediated behavioural responses by antidepressants: effects of single and repeated treatment.
    European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Clomipramine; Dopamine; Humans; Hydroxydopamines; Imipramine; Male; Maprotiline; Rats; Rats, Inbred Strains; Stereotyped Behavior; Time Factors

1979
Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.
    Pharmacology, 1977, Volume: 15, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Butyrophenones; Catecholamines; Chlorpromazine; Cocaine; Levodopa; Morphine; Pimozide; Rats; Receptors, Adrenergic; Reserpine; Restraint, Physical; Stomach Ulcer; Sympathomimetics; Trifluperidol

1977
Effects of viloxazine, an antidepressant agent, on biogenic amine uptake mechanisms and related activities.
    Canadian journal of physiology and pharmacology, 1976, Volume: 54, Issue:4

    Topics: Amitriptyline; Animals; Apomorphine; Biogenic Amines; Brain; Desipramine; Drug Synergism; Gastric Juice; Imipramine; In Vitro Techniques; Levodopa; Mice; Morpholines; Myocardium; Norepinephrine; Oxotremorine; Pupil; Rats; Reflex; Reserpine; Serotonin; Tyramine; Viloxazine

1976
[Behavioral pharmacology of a new antidepressant, lopramine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1976, Volume: 72, Issue:5

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Avoidance Learning; Blepharoptosis; Body Temperature; Catalepsy; Dibenzazepines; Drug Synergism; Emotions; Humans; Imipramine; Lethal Dose 50; Levodopa; Male; Methamphetamine; Mice; Motor Activity; Muscle Relaxation; Oxotremorine; Physostigmine; Rats; Stereotyped Behavior

1976
Pharmacological studies of drug action on CNS, with special reference to effects of maprotiline.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:3

    Topics: Action Potentials; Amitriptyline; Animals; Anthracenes; Antiemetics; Apomorphine; Body Weight; Cats; Chlorpromazine; Crowding; Dogs; Humans; Imipramine; Male; Maprotiline; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Rats; Reflex; Reflex, Monosynaptic; Spatial Behavior; Spinal Cord; Stereotyped Behavior

1975
[Behavior pharmacology of maprotiline, a new antidepressant].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: Aggression; Amitriptyline; Animals; Anthracenes; Apomorphine; Behavior, Animal; Body Temperature; Catalepsy; Escape Reaction; Eyelids; Haloperidol; Humans; Imipramine; Levodopa; Maprotiline; Methamphetamine; Mice; Motor Activity; Oxotremorine; Physostigmine; Rats; Reserpine; Sleep; Tetrabenazine

1975
[An experimental study of the antidepressive properties of captopril].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:11

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Captopril; Haloperidol; Male; Mice; Motor Activity; Physical Exertion; Stereotyped Behavior; Sulpiride; Swimming

1991
Assessment of anti-reserpine and anti-apomorphine activities of some psychic energizers in pigeons.
    Psychopharmacologia, 1969, Volume: 15, Issue:4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Columbidae; Deanol; Desipramine; Female; Hydrazines; Imipramine; Male; Opipramol; Orphenadrine; Reserpine; Vomiting

1969
Apomorphine provoked stereotype in the dog.
    Psychopharmacologia, 1972, Volume: 26, Issue:4

    Topics: Amitriptyline; Animals; Anisoles; Apomorphine; Atropine; Behavior, Animal; Benzamides; Benztropine; Diazepam; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethylamines; Female; Fluphenazine; Haloperidol; Humans; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Piperazines; Receptors, Drug; Scopolamine; Stereotyped Behavior; Xanthenes

1972
[Stereotypy following amphetamine and apomorphine and its influencing by drugs].
    Psychopharmacologia, 1971, Volume: 21, Issue:3

    Topics: Amitriptyline; Amphetamine; Animals; Apomorphine; Behavior, Animal; Desipramine; Drug Synergism; Female; Imipramine; Mastication; Mice; Rats; Tranquilizing Agents

1971
Neuropharmacology of apomorphine.
    Activitas nervosa superior, 1970, Volume: 12, Issue:3

    Topics: Amitriptyline; Animals; Apomorphine; Arousal; Behavior, Animal; Benactyzine; Chlorpromazine; Electroencephalography; Imipramine; Nervous System; Perphenazine; Rats

1970
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
Role of catecholaminesi in compulsive gnawing behaviour in mice.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Amitriptyline; Animals; Apomorphine; Catecholamines; Compulsive Behavior; Dihydroxyphenylalanine; Dopamine; Humans; Imipramine; Mastication; Methyltyrosines; Mice; Motor Activity; Stimulation, Chemical; Thiocarbamates

1968
Repeated treatment with antidepressant drugs increases the behavioural response to apomorphine.
    Journal of neural transmission, 1984, Volume: 60, Issue:3-4

    Topics: Amitriptyline; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Citalopram; Drug Synergism; Imipramine; Male; Mianserin; Propylamines; Rats; Rats, Inbred Strains; Zimeldine

1984
The effect of amitriptyline treatment on the growth hormone response to apomorphine.
    Psychopharmacology, 1984, Volume: 83, Issue:4

    Topics: Adult; Amitriptyline; Apomorphine; Growth Hormone; Humans; Male; Time Factors

1984
Pharmacological screening of the nude mouse with respect to some neuroactive drugs.
    Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:2

    Topics: Amitriptyline; Analgesics; Animals; Anticonvulsants; Antidepressive Agents; Apomorphine; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Morphine; Nervous System; Stereotyped Behavior

1983
Dopamine autoreceptor subsensitivity: a mechanism common to the treatment of depression and the induction of amphetamine psychosis.
    Biological psychiatry, 1981, Volume: 16, Issue:8

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents, Tricyclic; Apomorphine; Depressive Disorder; Electroshock; Humans; Imipramine; In Vitro Techniques; Iprindole; Neurons; Psychoses, Substance-Induced; Receptors, Dopamine; Substantia Nigra; Time Factors

1981