Page last updated: 2024-08-17

apomorphine and alpha-synuclein

apomorphine has been researched along with alpha-synuclein in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Mandel, S; Maor, G; Youdim, MB1
Chesselet, MF; Fleming, SM; Hutson, CB; Levine, MS; Masliah, E; Rockenstein, E; Salcedo, J1
Debetto, P; Giusti, P; Guidolin, D; Negro, A; Peroni, D; Recchia, A; Rota, D; Skaper, SD1
Johansson, SM; Modo, MM; Vernon, AC1
Bähr, M; Garrido, M; Kügler, S; Taschenberger, G; Tereshchenko, Y; Zhevtsova, Z1
An, CN; Pu, XP; Sun, SY1
Brekk, OR; Kirik, D; Landeck, N; Papadopoulou-Daifoti, Z; Papasilekas, T; Pitychoutis, PM; Stefanis, L; Xilouri, M1
Aebischer, P; Bensadoun, JC; Coune, PG; Schneider, BL1
Bao, XQ; Kong, LB; Kong, XC; Sun, H; Wu, LY; Zhang, D1
Auburger, G; Bez, F; Brehm, N; Carlsson, T; Cenci, MA; Gispert, S; Kern, B1
Deng, Y; Lu, J; Ma, H; Qing, H; Sun, F1
Chen, NH; Chu, SF; Li, J; Liu, Y; Song, LK; Sun, JD; Yuan, YH1
Li, K; Li, Y; Na, S; Wu, J; Xie, X; Yang, J; Yang, Z; Yu, X; Yue, J1
Felten, P; Heurtaux, T; Kirchmeyer, M; Koncina, E; Mittelbronn, M; Richart, L; Schohn, H; Uriarte Huarte, O1
Abuleil, A; Ajagbe, AO; Alhendawi, BHM; Badri, R; Chaaya, C; Chalhoub, E; Korkusuz, AK; Onyeaka, H; Uwishema, O; Yücel, AN1
Mohajeri, D; Nourazar, MA; Sokouti, H1

Other Studies

16 other study(ies) available for apomorphine and alpha-synuclein

ArticleYear
Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
    Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Apomorphine; Catechin; Disease Models, Animal; Free Radicals; Iron; Iron Chelating Agents; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Synucleins; Ubiquitin

2004
Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein.
    Neuroscience, 2006, Nov-03, Volume: 142, Issue:4

    Topics: alpha-Synuclein; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benserazide; Brain; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Genetic Predisposition to Disease; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Parkinson Disease; Stereotypic Movement Disorder

2006
Generation of a alpha-synuclein-based rat model of Parkinson's disease.
    Neurobiology of disease, 2008, Volume: 30, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dopamine Agonists; Gene Expression Regulation; Gene Products, tat; Genetic Vectors; Green Fluorescent Proteins; Male; Motor Activity; Oxidopamine; Parkinson Disease; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2008
Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
    BMC neuroscience, 2010, Jan-05, Volume: 11

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Apomorphine; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Dopamine Agonists; Iron; Magnetic Resonance Imaging; Male; Mesencephalon; Motor Activity; Neurons; Parkinsonian Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Substantia Nigra

2010
Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons.
    Acta neuropathologica, 2011, Volume: 121, Issue:4

    Topics: alpha-Synuclein; Analysis of Variance; Animals; Apomorphine; Catalytic Domain; Cell Survival; Cysteine; Disease Models, Animal; Dopamine; Dopamine Agonists; Female; Gene Expression Regulation; Gliosis; Glutathione; Glutathione Reductase; Green Fluorescent Proteins; Movement; Nerve Degeneration; Rats; Rats, Wistar; RNA, Small Interfering; Sensation Disorders; Stereotyped Behavior; Substantia Nigra; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins

2011
DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats.
    Brain research bulletin, 2012, Sep-01, Volume: 88, Issue:6

    Topics: alpha-Synuclein; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Dopaminergic Neurons; Drug Evaluation, Preclinical; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Ion Channels; Leupeptins; Male; Microinjections; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mitochondrial Uncoupling Proteins; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Oncogene Proteins; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Protein Deglycase DJ-1; Rats; Rats, Sprague-Dawley; Substantia Nigra; Superoxide Dismutase; Tyrosine 3-Monooxygenase

2012
Boosting chaperone-mediated autophagy in vivo mitigates α-synuclein-induced neurodegeneration.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 7

    Topics: alpha-Synuclein; Amphetamine; Analysis of Variance; Animals; Apomorphine; Autophagy; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Dependovirus; Dopamine; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Genetic Vectors; Green Fluorescent Proteins; Hemagglutinins; Humans; Lysosomal Membrane Proteins; Lysosomal-Associated Membrane Protein 2; Macrolides; Mice; Molecular Chaperones; Motor Activity; Nerve Degeneration; Neuroblastoma; Neurons; Rats; Transfection; Tyrosine 3-Monooxygenase

2013
Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease.
    Journal of Parkinson's disease, 2011, Volume: 1, Issue:4

    Topics: alpha-Synuclein; Animals; Apomorphine; Disease Models, Animal; Dopaminergic Neurons; Exploratory Behavior; Female; Forelimb; Genetic Vectors; Golgi Apparatus; Humans; Male; Mice; Mutation; Parkinson Disease; rab1 GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2011
Squamosamide derivative FLZ protected dopaminergic neuron by activating Akt signaling pathway in 6-OHDA-induced in vivo and in vitro Parkinson's disease models.
    Brain research, 2014, Feb-14, Volume: 1547

    Topics: alpha-Synuclein; Animals; Apomorphine; Benzeneacetamides; Cell Death; Disease Models, Animal; Dopamine Agonists; Dopaminergic Neurons; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Phenols; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Repressor Proteins; Signal Transduction; Transcription Factors; Tyrosine 3-Monooxygenase

2014
A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine.
    Molecular neurobiology, 2015, Volume: 52, Issue:3

    Topics: alpha-Synuclein; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Dyskinesias; Extracellular Signal-Regulated MAP Kinases; Humans; Locomotion; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mutation, Missense; Nerve Tissue Proteins; Parkinsonian Disorders; Phosphorylation; Point Mutation; Post-Synaptic Density; Prions; Promoter Regions, Genetic; Protein Processing, Post-Translational; Stereotyped Behavior; Substantia Nigra; Transgenes

2015
Comparison between α-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model.
    Biochemical and biophysical research communications, 2015, Sep-04, Volume: 464, Issue:4

    Topics: Age Factors; alpha-Synuclein; Amino Acid Substitution; Animals; Apomorphine; Brain; Disease Models, Animal; Dopaminergic Neurons; Immunohistochemistry; Male; Mutant Proteins; Mutation, Missense; Parkinsonian Disorders; Phosphorylation; Protein Aggregation, Pathological; Rats; Rats, Transgenic; Rats, Wistar; Recombinant Proteins; Torsion Abnormality

2015
Environment-contact administration of rotenone: A new rodent model of Parkinson's disease.
    Behavioural brain research, 2015, Nov-01, Volume: 294

    Topics: alpha-Synuclein; Animals; Apomorphine; Body Weight; Brain; Disease Progression; Dopamine; Dopamine Agonists; Enteric Nervous System; Environmental Exposure; Housing, Animal; Male; Mice, Inbred C57BL; Motor Activity; Muscle, Skeletal; Neurons; Olfactory Perception; Parkinsonian Disorders; Rotenone; Tyrosine 3-Monooxygenase

2015
The Protective Role of Brain CYP2J in Parkinson's Disease Models.
    Oxidative medicine and cellular longevity, 2018, Volume: 2018

    Topics: alpha-Synuclein; Animals; Apomorphine; Brain; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytochrome P-450 Enzyme System; Disease Models, Animal; Dopaminergic Neurons; Humans; Lipopolysaccharides; Male; Myeloid Differentiation Factor 88; NF-E2-Related Factor 2; Oxidopamine; Parkinson Disease; Rats; Rats, Wistar; Signal Transduction; Toll-Like Receptor 4

2018
Apomorphine Reduces A53T α-Synuclein-Induced Microglial Reactivity Through Activation of NRF2 Signalling Pathway.
    Cellular and molecular neurobiology, 2022, Volume: 42, Issue:8

    Topics: alpha-Synuclein; Animals; Antioxidants; Apomorphine; Dopamine; Dopamine Agonists; Free Radical Scavengers; Humans; Mice; Microglia; NF-E2-Related Factor 2; Parkinson Disease; RNA, Small Interfering

2022
The understanding of Parkinson's disease through genetics and new therapies.
    Brain and behavior, 2022, Volume: 12, Issue:5

    Topics: alpha-Synuclein; Apomorphine; Dopaminergic Neurons; Humans; Hypokinesia; Parkinson Disease; Tremor

2022
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
    Physiological research, 2022, Aug-31, Volume: 71, Issue:4

    Topics: alpha-Synuclein; Animals; Antioxidants; Apomorphine; Curcumin; Disease Models, Animal; Glutathione Peroxidase; Malondialdehyde; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Parkinson Disease; Rats; Substantia Nigra

2022