apomorphine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (17.74) | 18.7374 |
| 1990's | 24 (38.71) | 18.2507 |
| 2000's | 16 (25.81) | 29.6817 |
| 2010's | 10 (16.13) | 24.3611 |
| 2020's | 1 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Clarke, FH; de Jesus, R; Hutchison, A; Sills, MA; Stone, GA; Sylvester, L; Williams, M | 1 |
| Bhatnagar, RK; Cannon, JG; Jackson, H; Leonard, P; Long, JP | 1 |
| Arvidsson, LE; Carlsson, A; Hacksell, U; Hjorth, S; Johansson, A; Lindberg, P; Nilsson, JL; Sanchez, D; Wikström, H | 1 |
| Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF | 1 |
| Chidester, CG; Haadsma-Svensson, SR; Lahti, RA; Lin, CH; McCall, RB; Phillips, G; Piercey, MF; Schreur, PJ; Smith, MW; Von Voigtlander, PF | 1 |
| Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A | 1 |
| Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S | 1 |
| Alberts, I; Harding, WW; Juarez, R; Karki, A; Namballa, HK | 1 |
| Dourish, CT; Williams, AR | 1 |
| Ewing, FE; Furman, JS; Heym, JH; Howard, HR; Lowe, JA; Nagel, AA; Newman, ME; Schmidt, AW; Seeger, TF; Seymour, PA | 1 |
| De Boer, T; Florijn, WJ; Tonnaer, JA; Van Nispen, JW; Versteeg, DH | 1 |
| Cespuglio, R; Chastrette, N; Jouvet, M; Lin, YL | 1 |
| Backus, LI; Bramwell, SR; Grahame-Smith, DG; Hjorth, S; Sharp, T | 1 |
| De Boer, T; De Vos, CJ; Tonnaer, JA; Van Delft, AM | 1 |
| Carlsson, A; Fredriksson, K; Grol, CJ; Hacksell, U; Johansson, AM; Sundell, S; Svensson, K | 1 |
| Backus, LI; Grahame-Smith, DG; Sharp, T | 1 |
| Lum, JT; Piercey, MF | 1 |
| Gerber, R; Gerhardt, SC; Liebman, JM | 1 |
| Goodwin, GM; Green, AR | 1 |
| De Souza, RJ; Goodwin, GM; Green, AR | 1 |
| Carlsson, A; Johansson, AM; Magnusson, T; Svensson, K | 1 |
| Ahlenius, S; Fernández-Guasti, A; Hjorth, S; Larsson, K | 1 |
| Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Sanchez, D; Svensson, K; Wikström, H | 1 |
| Carlsson, A; Hajos, M; Hjorth, S; Svensson, K | 1 |
| Baldessarini, RJ; Froimowitz, M; Neumeyer, JL | 1 |
| Bone, RG; Villar, HO | 1 |
| Engel, JA; Hjorth, S; Svensson, L; Zhang, J | 1 |
| Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT | 1 |
| Caine, SB; Geyer, MA; Swerdlow, NR | 1 |
| Ikeda, K; Ishibashi, T; Ishida, K; Kato, T; Nakamura, M; Ohno, Y | 1 |
| Rijnders, HJ; Slangen, JL | 1 |
| Kamei, H; Kameyama, T; Nabeshima, T | 1 |
| Argiolas, A; Melis, MR; Stancampiano, R | 1 |
| Kleven, MS; Koek, W | 1 |
| Christoffersen, CL; Meltzer, LT | 1 |
| Comoy, E; Lesourd, M; Protais, P | 1 |
| Baker, GB; Bourin, M; Colombel, MC; Redrobe, JP | 1 |
| Kinney, GG; Saywell, KL; Tricklebank, MD; Wilkinson, LO | 1 |
| Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T | 1 |
| Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J | 1 |
| de Moes, J; Feenstra, RW; Hofma, JJ; Kling, H; Kruse, CG; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA | 1 |
| Cervo, L; De Deurwaerdère, P; Spampinato, U; Stinus, L | 1 |
| Gobert, A; Lejeune, F; Millan, MJ | 1 |
| Adaikan, PG; Hayes, ES | 1 |
| Ago, Y; Baba, A; Matsuda, T; Sakaue, M | 1 |
| van den Buuse, M | 1 |
| Lawrence, AJ; Martin, S; van den Buuse, M | 1 |
| Carey, RJ; Damianopoulos, E; DePalma, G; Huston, JP; Müller, CP; Shanahan, A | 1 |
| Cools, AR; de Jong, TR; Olivier, B; Pattij, T; Uitterdijk, A; van der Graaf, PH; Veening, JG; Waldinger, MD | 1 |
| Carey, RJ; Damianopoulos, E; DePalma, G; Shanahan, A | 1 |
| Ashby, CR; McCreary, AC; Nakamura, K; Suzuki, K | 1 |
| Choy, KH; van den Buuse, M | 1 |
| Fujita, S; Hatanaka, H; Kiguchi, M; Koshikawa, N; Lee, J; Suga, K; Terakado, M | 1 |
| Blier, P; El Mansari, M; Ghanbari, R; Shahid, M | 1 |
| Braszko, JJ | 1 |
| Chavez, C; Gogos, A; Kwek, P; van den Buuse, M | 1 |
| Ermani, M; Freo, U; Merico, A; Ori, C | 1 |
| Chan, JS; de Jong, TR; Olivier, B; Oosting, RS; Snoeren, EM; Waldinger, MD | 1 |
| Filli, L; Schwab, ME; Weinmann, O; Zörner, B | 1 |
| Seftel, A | 1 |
| Dalphin, N; Hyland, BI; Li, Y | 1 |
| Chen, L; Feng, J; Han, LN; Li, LB; Liu, J; Sun, YN; Wang, T; Wang, Y; Zhang, L; Zhang, QJ | 1 |
62 other study(ies) available for apomorphine and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
2H-[1]benzopyrano[3,4-b]pyridines: synthesis and activity at central monoamine receptors.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Models, Molecular; Pyridines; Rats; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Neurotransmitter; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
5-HT1A-receptor antagonism: N-alkyl derivatives of (R)-(-)-8,11-dimethoxynoraporphine.
Topics: Animals; Aporphines; Behavior, Animal; Cats; Chemical Phenomena; Chemistry; Dopamine Agents; Hemodynamics; In Vitro Techniques; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Serotonin; Stereoisomerism | 1989 |
Monophenolic octahydrobenzo[f]quinolines: central dopamine- and serotonin-receptor stimulating activity.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; In Vitro Techniques; Motor Activity; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin | 1982 |
Centrally acting serotonergic and dopaminergic agents. 1. Synthesis and structure-activity relationships of 2,3,3a,4,5,9b-hexahydro-1H-benz[e]indole derivatives.
Topics: Animals; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship | 1993 |
Centrally acting serotonergic and dopaminergic agents. 2. Synthesis and structure-activity relationships of 2,3,3a,4,9,9a-hexahydro-1H-benz[f]indole derivatives.
Topics: Animals; Binding Sites; Brain; Cats; Cattle; Dopamine Agents; Indoles; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes | 1993 |
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming | 2015 |
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines | 2019 |
Identification of C10 nitrogen-containing aporphines with dopamine D
Topics: Aporphines; Dopamine Agonists; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Docking Simulation; Molecular Structure; Receptors, Dopamine D1; Receptors, Dopamine D5; Structure-Activity Relationship | 2020 |
Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Eating; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin Antagonists; Stereotyped Behavior | 1992 |
1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Apomorphine; Autoradiography; Behavior, Animal; Dopamine Antagonists; Haloperidol; Ketanserin; Locomotion; Male; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetrahydronaphthalenes | 1991 |
ACTH/MSH-like peptides inhibit the binding of dopaminergic ligands to the dopamine D2 receptor in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amino Acid Sequence; Animals; Apomorphine; Cosyntropin; Dopamine Agents; In Vitro Techniques; Kinetics; Ligands; Male; Melanocyte-Stimulating Hormones; Molecular Sequence Data; Peptide Fragments; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Structure-Activity Relationship; Tetrahydronaphthalenes | 1991 |
Proopiomelanocortin (POMC)-derived peptides and sleep in the rat. Part 2--Aminergic regulatory processes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; alpha-MSH; Animals; Apomorphine; Bromocriptine; Corticotropin-Like Intermediate Lobe Peptide; Dopamine; Dopamine Antagonists; Hypoxia; Male; Peptide Fragments; Pro-Opiomelanocortin; Rats; Receptors, Dopamine; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Tetrahydronaphthalenes | 1990 |
Further investigation of the in vivo pharmacological properties of the putative 5-HT1A antagonist, BMY 7378.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Apomorphine; Brain Chemistry; Dialysis; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
Neurochemical studies with the potential antipsychotic compound trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Benzazepines; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dibenzoxepins; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Membranes; Mianserin; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Yohimbine | 1990 |
Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Binding, Competitive; Cattle; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Crystallography; Dihydroxyphenylalanine; Dopamine Antagonists; In Vitro Techniques; Isomerism; Male; Molecular Conformation; Molecular Structure; Motor Activity; Rats; Reserpine; Spiperone; Structure-Activity Relationship; Tetrahydronaphthalenes; X-Ray Diffraction | 1990 |
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes | 1990 |
Electrophysiological effects of dopamine autoreceptor antagonists, (+)-AJ 76 and (+)-UH 232.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dendrites; Dopamine; Dopamine Antagonists; Electrophysiology; Feedback; Haloperidol; In Vitro Techniques; Male; Naphthalenes; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra; Tetrahydronaphthalenes | 1990 |
Effects of 5-HT1A agonists and 5-HT2 antagonists on haloperidol-induced dyskinesias in squirrel monkeys: no evidence for reciprocal 5-HT-dopamine interaction.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Avoidance Learning; Buspirone; Dopamine; Haloperidol; Male; Movement Disorders; Pyrimidinones; Saimiri; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1989 |
A behavioural and biochemical study in mice and rats of putative selective agonists and antagonists for 5-HT1 and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Body Temperature; Brain Chemistry; Histamine H2 Antagonists; Hydroxyindoleacetic Acid; Indoles; Kinetics; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Propranolol; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes | 1985 |
The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). A model of presynaptic 5-HT1 function.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Apomorphine; Benzodiazepinones; Body Temperature; Clonidine; Fenclonine; Flumazenil; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Naphthalenes; Tetrahydronaphthalenes; Time Factors | 1985 |
(+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists.
Topics: 4-Butyrolactone; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brain; Male; Methyltyrosines; Motor Activity; Naphthalenes; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Tetrahydronaphthalenes | 1986 |
Separation of dopaminergic and serotonergic inhibitory mechanisms in the mediation of estrogen-induced lordosis behaviour in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine; Ergolines; Estradiol; Female; Haloperidol; Lisuride; Male; Ovariectomy; Posture; Quinpirole; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Tetrahydronaphthalenes | 1987 |
(+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.
Topics: 4-Butyrolactone; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Serotonin; Stereoisomerism; Tetrahydronaphthalenes | 1986 |
In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Functional Laterality; Hydroxydopamines; Male; Naphthalenes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tetrahydronaphthalenes | 1988 |
A stereochemical explanation of the dopamine agonist and antagonist activity of stereoisomeric pairs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Dopamine Antagonists; Molecular Conformation; Naphthalenes; Piperidines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes; Thermodynamics | 1986 |
Discriminating D1 and D2 agonists with a hydrophobic similarity index.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Apomorphine; Benzazepines; Chemical Phenomena; Chemistry, Physical; Chromans; Dopamine Agonists; Drug Design; Ergolines; Indoles; Ligands; Lisuride; Models, Molecular; Phenanthridines; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2 | 1995 |
Changes in the acoustic startle response and prepulse inhibition of acoustic startle in rats after local injection of pertussis toxin into the ventral tegmental area.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dialysis; Male; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Reflex, Startle; Time Factors; Ventral Tegmental Area; Virulence Factors, Bordetella | 1995 |
Effects of atypical antipsychotic agents on social behavior in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior | 1993 |
Effects of D3/D2 dopamine receptor agonists and antagonists on prepulse inhibition of acoustic startle in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Apomorphine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Reflex, Startle; Schizophrenia; Tetrahydronaphthalenes | 1995 |
Effects of chronic treatments with SM-9018, a potential atypical neuroleptic, on behavioral dopaminergic and serotonergic sensitivities in rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Dopamine; Haloperidol; Indoles; Isoindoles; Male; Motor Activity; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Stereotyped Behavior; Thiazoles | 1995 |
The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Benzazepines; Buspirone; Chlordiazepoxide; Discrimination Learning; Discrimination, Psychological; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Generalization, Stimulus; Male; Methysergide; Rats; Rats, Wistar; Reinforcement Schedule | 1993 |
SKF-10,047 reverses stress-induced motor suppression: interaction with dopaminergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Dopamine; Electroshock; Guanidines; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Pentazocine; Phenazocine; Pimozide; Pyrimidines; Receptors, sigma; Stress, Psychological | 1994 |
Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Oxytocin; Penile Erection; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin; Serotonin Receptor Agonists; Synaptic Transmission; Yawning | 1994 |
Dopamine D2 receptors play a role in the (-)-apomorphine-like discriminative stimulus effects of (+)-PD 128907.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Benzopyrans; Conditioning, Operant; Discrimination, Psychological; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Male; Oxazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2 | 1997 |
Reversal of haloperidol-induced extrapyramidal side effects in cebus monkeys by 8-hydroxy-2-(di-n-propylamino)tetralin and its enantiomers.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Apomorphine; Basal Ganglia Diseases; Cebus; Female; Haloperidol; Male; Serotonin Receptor Agonists; Stereoisomerism; Time Factors | 1998 |
Similar pharmacological properties of 8-OH-DPAT and alnespirone (S 20499) at dopamine receptors: comparison with buspirone.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzazepines; Buspirone; Corpus Striatum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Mice; Piperazines; Raclopride; Salicylamides; Serotonin; Serotonin Antagonists; Spiro Compounds; Tritium | 1998 |
Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Antidepressive Agents; Apomorphine; Brain; Clonidine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Indoles; Male; Mice; Motor Activity; Norepinephrine; Paroxetine; Pindolol; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1998 |
Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Amphetamine; Animals; Apomorphine; Dopamine; Dopamine Agonists; Male; Motor Activity; Nucleus Accumbens; Oxidopamine; Phencyclidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Dopamine; Reflex, Startle; Species Specificity; Time Factors | 1999 |
5-HT1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Apomorphine; Behavior, Animal; Buspirone; Exploratory Behavior; Male; Motor Activity; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2000 |
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine | 2001 |
New 1-aryl-4-(biarylmethylene)piperazines as potential atypical antipsychotics sharing dopamine D(2)-receptor and serotonin 5-HT(1A)-receptor affinities.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Benzoxazoles; Dopamine Antagonists; Drug Design; Drug Evaluation, Preclinical; Mice; Piperazines; Rats; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spiperone; Structure-Activity Relationship | 2001 |
Central 5-HT(4) receptors and dopamine-dependent motor behaviors: searching for a functional role.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Catalepsy; Central Nervous System; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Indoles; Injections, Intraventricular; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior; Sulfonamides | 2002 |
The selective neurokinin (NK)(1) antagonist, GR205,171, stereospecifically enhances mesocortical dopaminergic transmission in the rat: a combined dialysis and electrophysiological study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antiemetics; Apomorphine; Depression; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Extracellular Space; Isomerism; Male; Microdialysis; Neural Pathways; Neurokinin-1 Receptor Antagonists; Piperidines; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Neurokinin-1; Serotonin Receptor Agonists; Synaptic Transmission; Tetrazoles; Up-Regulation; Ventral Tegmental Area | 2002 |
The effects of 5HT(1) agonists on erection in rats in vivo and rabbit corpus cavernosum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine Agonists; Male; Muscle, Smooth; Penile Erection; Penis; Pressure; Quinoxalines; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2002 |
The 5-HT1A receptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Administration, Oral; Animals; Apomorphine; Dioxanes; Dioxoles; Dizocilpine Maleate; Drug Interactions; Male; Mice; Piperazines; Pyridines; Reflex, Startle; Risperidone; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Social Isolation | 2003 |
Prepulse inhibition of acoustic startle in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Hypertension; Male; Neural Inhibition; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reflex, Acoustic; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Prepulse inhibition in fawn-hooded rats: increased sensitivity to 5-HT1A receptor stimulation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Neural Inhibition; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Pharmacological inhibition of DA- and 5-HT activity blocks spontaneous and cocaine-activated behavior: reversal by chronic cocaine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Cocaine; Conditioning, Classical; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 2005 |
Individual differences in male rat ejaculatory behaviour: searching for models to study ejaculation disorders.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Brain; Cell Count; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Ejaculation; Exploratory Behavior; Female; Immunohistochemistry; Male; Maze Learning; Oncogene Proteins v-fos; Oxytocin; Rats; Rats, Wistar; Reaction Time; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunction, Physiological; Stereotyped Behavior | 2005 |
Stimulus gated cocaine sensitization: interoceptive drug cue control of cocaine locomotor sensitization.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Central Nervous System Stimulants; Cocaine; Cues; Dopamine Agonists; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 2005 |
The acute and chronic administration of (+/-)-8-hydroxy-2-(Di-n-propylamino)tetralin significantly alters the activity of spontaneously active midbrain dopamine neurons in rats: an in vivo electrophysiological study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analysis of Variance; Animals; Apomorphine; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Male; Mesencephalon; Neurons; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 2006 |
Attenuated disruption of prepulse inhibition by dopaminergic stimulation after maternal deprivation and adolescent corticosterone treatment in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Animals, Newborn; Apomorphine; Autoradiography; Brain Chemistry; Corticosterone; Data Interpretation, Statistical; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Drug Implants; Hyperkinesis; Maternal Deprivation; Motor Activity; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin Receptor Agonists | 2008 |
5-HT(1A) and 5-HT(1B) receptors in the ventrolateral striatum differentially modulate apomorphine-induced jaw movements in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Benzamides; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; Electromyography; Magnetics; Male; Mandible; Masseter Muscle; Microinjections; Movement; Neck Muscles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2008 |
Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Amphetamines; Animals; Apomorphine; Brain; Clonidine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists | 2009 |
(+)-UH 232, a partial agonist of the D3 dopamine receptors, attenuates cognitive effects of angiotensin IV and des-Phe(6)-angiotensin IV in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apomorphine; Avoidance Learning; Cognition; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Partial Agonism; Exploratory Behavior; Male; Maze Learning; Rats; Receptors, Angiotensin; Receptors, Dopamine D3; Recognition, Psychology; Stereotyped Behavior | 2010 |
Estrogen treatment blocks 8-hydroxy-2-dipropylaminotetralin- and apomorphine-induced disruptions of prepulse inhibition: involvement of dopamine D1 or D2 or serotonin 5-HT1A, 5-HT2A, or 5-HT7 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists | 2010 |
Chronic treatment with fluoxetine decreases cerebral metabolic responses to the 5-HT1A agonist 8-hydroxy-2(di-N-propylamino)tetralin and increases those to the 5-HT2A/2C agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane and to the dopaminergic agonist
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Apomorphine; Brain; Dopamine Agonists; Down-Regulation; Drug Administration Schedule; Fluoxetine; Male; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Up-Regulation | 2010 |
A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Female; Male; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunctions, Psychological | 2011 |
Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brown-Sequard Syndrome; Clonidine; Disease Models, Animal; Dopamine Agonists; Drug Interactions; Female; Functional Laterality; Methoxamine; Motor Activity; Motor Neurons; Movement Disorders; Quipazine; Rats; Rats, Inbred Lew; Recovery of Function; Serotonin; Serotonin Receptor Agonists; Spinal Cord Injuries; Sympatholytics; Sympathomimetics; Tyrosine 3-Monooxygenase | 2011 |
Re: A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine Agonists; Female; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sexual Dysfunctions, Psychological | 2011 |
Association with reward negatively modulates short latency phasic conditioned responses of dorsal raphe nucleus neurons in freely moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Apomorphine; Conditioning, Psychological; Cues; Dopamine Agonists; Male; Neurons; Raphe Nuclei; Rats; Rats, Wistar; Reaction Time; Reward; Serotonin Receptor Agonists; Wakefulness | 2013 |
The theta-related firing activity of parvalbumin-positive neurons in the medial septum-diagonal band of Broca complex and their response to 5-HT1A receptor stimulation in a rat model of Parkinson's disease.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Apomorphine; Desipramine; Diagonal Band of Broca; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Parvalbumins; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Substantia Nigra; Theta Rhythm | 2014 |