Page last updated: 2024-08-17

apomorphine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

apomorphine has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199013 (17.33)18.7374
1990's29 (38.67)18.2507
2000's24 (32.00)29.6817
2010's7 (9.33)24.3611
2020's2 (2.67)2.80

Authors

AuthorsStudies
Bard, B; Carrupt, PA; Martel, S1
Wesemann, W1
Kunow, M; Löschmann, PA; Wachtel, H1
Chen, S1
Boyce, S; Crossman, AR; Mitchell, IJ; Sambrook, MA1
Bédard, PJ; Filion, M; Tremblay, L1
Kondo, T; Narabayashi, H; Nishi, K1
Boyce, S; Iversen, SD; Rupniak, NM; Steventon, MJ1
Archer, T; Fredriksson, A; Sundström, E1
Bakay, RA; Byrd, LD; Colbassani, HJ; Herring, CJ; Iuvone, PM; Mandir, A; Sweeney, KM; Watts, RL1
Deutch, AY; Roth, RH; Sladek, JR; Yurek, DM1
Cantrill, RC; Kurstjens, NP1
Calderon, SF; el-Etri, MM; Norman, AB; Sanberg, PR; Shipley, MT; Weissman, EM; Zubrycki, EM1
Boyce, S; Clarke, CE; Crossman, AR; Robertson, RG; Sambrook, MA1
Bédard, PJ; Bouchard, S; Boucher, R; Di Paolo, T; Falardeau, P1
Fung, YK; Lau, YS1
Bankiewicz, KS; Chiueh, CC; Doppman, JL; Jacobowitz, DM; Kopin, IJ; Oldfield, EH1
Neumeyer, JL; Szabo, S1
Jarvis, MF; Wagner, GC1
Cohen, O; Globus, M; Melamed, E; Rosenthal, J; Uzzan, A1
Andrews, JS; Biggins, JA; Candy, JM; Edwardson, JA; Keith, AB; Sahgal, A; Turner, JD; Wright, C1
Lahaye, D; Markstein, R1
Boyce, S; Jenner, P; Kelly, E; Marsden, CD; Reavill, C1
Akai, T; Kuno, S; Mizuta, E; Ozawa, M; Yamaguchi, M1
Christoffersen, CL; Corbin, AE; Heffner, TG; Meltzer, LT; Ninteman, FW; Serpa, KA; Wiley, JN; Wise, LD1
Pontieri, FE; Porrino, LJ; Sokoloff, L; Viola, JJ1
Block, F; Clement, HW; Grote, C; Sontag, KH; Wesemann, W1
Hikosaka, O; Kato, M; Kori, A; Matsumura, M; Miyashita, N; Usui, S1
Roeltgen, DP; Schneider, JS; Sun, ZQ1
Bankiewicz, KS; Cummins, A; Oldfield, EH; Palmatier, M; Plunkett, RJ1
Aosaki, T; Graybiel, AM; Kimura, M1
Herrero, MT; Laguna, J; Luquin, MR; Obeso, JA1
Agnati, LF; Altamimi, U; Andbjer, B; Finnman, UB; Fuxe, K; Goldstein, M; Janson, AM; Rosén, L; Ueki, A1
Kuno, S; Mizuta, E; Sasa, M; Yoshida, O; Yoshimura, N1
Benabid, AL; Gervason, CL; Jeanneau-Nicolle, E; Limousin, P; Pollak, P1
Yoshida, M1
Barnéoud, P; Boireau, A; Doble, A; Dubédat, P; Mazadier, M; Miquet, JM; Parmentier, S1
Heneka, MT; Klockgether, T; Kunow, M; Löschmann, PA; Schulz, JB; Wachtel, H; Wüllner, U1
Kuno, S1
Guerra, MJ; Labandeira-García, JL; López-Martín, E; Rozas, G1
Berkuzki, T; Grünblatt, E; Mandel, S; Youdim, MB1
Hashimoto, T; Izawa, Y; Kato, T; Moriizumi, T; Yokoyama, H1
Grünblatt, E; Mandel, S; Youdim, MB1
Jenner, P; Smith, LA; Treseder, SA1
Gassen, M; Gross, A; Grünblatt, E; Mandel, S; Youdim, MB1
Bezard, E; Bioulac, B; Boraud, T; Gross, CE1
Grünblatt, E; Mandel, S; Maor, G; Youdim, MB2
Brotchie, JM; Crossman, AR; Fox, SH; Henry, B; Hill, MP; Peggs, D1
Brotchie, JM; Crossman, AR; Silverdale, MA1
Battaglia, G; Busceti, CL; Cuomo, L; De Blasi, A; Fornai, F; Giorgi, FS; Nicoletti, F; Orzi, F; Ruggieri, S1
Castri, P; Fornai, F; Orzi, F1
Battaglia, G; Busceti, CL; Fornai, F; Gesi, M; Lenzi, P; Nicoletti, F; Orzi, F; Rampello, L; Ruggieri, S; Soldani, P1
Matsumura, M1
Cannizzaro, C; Jackson, MJ; Jenner, P; Maratos, EC; Pearce, RK1
Bjarkam, C; Cumming, P; Gillings, NM; Gjedde, A; Jensen, SB1
Bibbiani, F; Castagnoli, N; Chase, TN; Chen, JF; Oh, JD; Petzer, JP; Schwarzschild, MA1
Hanger, D; Joyce, JN; Reploge, M; Yarkov, AV1
Bergman, H; Fainstein, N; Morris, G; Nevet, A; Saban, G1
Mandel, S; Maor, G; Youdim, MB1
Bibbiani, F; Chase, TN; Costantini, LC; Patel, R1
Mewes, K; Russo, GS; Rye, DB; Vitek, JL; Zhang, J1
Billinton, A; Brown, M; Chapman, H; Quinn, LP; Stean, TO; Upton, N; Vidgeon-Hart, M; Virley, DJ1
Brotchie, JM; Fox, SH; Gomez-Ramirez, J; Johnston, TH; Pires, D; Visanji, NP; Voon, V1
Ding, XJ; Tao, EX; Xu, YM1
Ai, Y; Andersen, A; Ding, F; Forman, E; Gash, DM; Gerhardt, GA; Grondin, R; Hardy, P; Luan, L; Zhang, Z1
Ding-Fang, C; Guo-Hua, W; Hong-Min, T; Hua-Wei, L; Jun, M; Jun-Peng, G; Shan, S; Wen-Wei, L; Xiang-Yu, W; Ya-Ling, H; Yan-Hong, T; Yi, F; Yue, F; Yun-Ke, Y1
Funayama, M; Hattori, N; Ikeda, K; Kitazawa, S; Shimo, Y; Shiotsuki, H; Takahashi, R; Takamatsu, Y; Yoshimi, K1
Bordet, R; Destée, A; Duhamel, A; Kreisler, A; Vanbesien-Mailliot, C1
Bortolanza, M; Brandão, ML; Carvalho, MC; Correia, D; Da Cunha, C; Dombrowski, PA; Dos Santos, LM; Eckart, MT; Miyoshi, E; Schwarting, RK; Wietzikoski, EC1
Andersen, AH; Forman, E; Gash, DM; Gerhardt, GA; Grondin, RC; Hardy, PA; Zhang, Z1
Li, J; Liao, S; Lin, Y; Liu, Y; Quan, H; Yang, Q1
Ai, Y; Andersen, AH; Evans, A; Forman, E; Gash, DM; Grondin, R; Hardy, PA; Yue, G; Yue, J; Zhang, R; Zhang, Z1
Tian, H; Xiao, W; Xue, B1
Kadiri, SK; Karkar, VV; Pal Roy, S; Rao Konijeti, S1

Reviews

3 review(s) available for apomorphine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Iron chelating, antioxidant and cytoprotective properties of dopamine receptor agonist; apomorphine.
    Journal of neural transmission. Supplementum, 2000, Issue:58

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Apomorphine; Chelating Agents; Dopamine Agonists; Humans; Iron; Parkinson Disease; Parkinsonian Disorders; Reactive Oxygen Species

2000
Apomorphine as a neuroprotective drug: a study in MPTP-treated mice and potential relevance to ischemia.
    Functional neurology, 2001, Volume: 16, Issue:4 Suppl

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Brain; Brain Ischemia; Dopamine Agents; Dopamine Agonists; Humans; Neuroprotective Agents

2001
Experimental parkinsonism in primates.
    Stereotactic and functional neurosurgery, 2001, Volume: 77, Issue:1-4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Apomorphine; Basal Ganglia; Bicuculline; Cerebral Cortex; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrocoagulation; GABA Antagonists; Globus Pallidus; Humans; Models, Neurological; MPTP Poisoning; Muscle Rigidity; Neurotoxins; Parkinsonian Disorders; Primates; Substance-Related Disorders; Substantia Nigra; Tegmentum Mesencephali; Thalamus

2001

Other Studies

72 other study(ies) available for apomorphine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Therapy of Morbus Parkinson and radical-induced neurotoxicity in the rat--in vivo voltammetric studies.
    Journal of neural transmission. Supplementum, 1992, Volume: 38

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Electrochemistry; Free Radicals; Haloperidol; Hydroxyindoleacetic Acid; Male; Memantine; Neurotoxins; Parkinson Disease; Rats; Rats, Wistar; Rotenone; Serotonin; Substantia Nigra

1992
Synergism of NBQX with dopamine agonists in the 6-OHDA rat model of Parkinson's disease.
    Journal of neural transmission. Supplementum, 1992, Volume: 38

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Drug Synergism; Lisuride; Male; Motor Activity; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Rats; Rats, Wistar; Stereotaxic Techniques; Substantia Nigra

1992
[Dopa-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated hemiparkinsonian monkeys].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamines; Animals; Apomorphine; Benserazide; Carboxy-Lyases; Drug Combinations; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca mulatta; Parkinson Disease, Secondary

1992
A 2-deoxyglucose study of the effects of dopamine agonists on the parkinsonian primate brain. Implications for the neural mechanisms that mediate dopamine agonist-induced dyskinesia.
    Brain : a journal of neurology, 1992, Volume: 115 ( Pt 3)

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Deoxyglucose; Female; Globus Pallidus; Levodopa; Macaca fascicularis; Male; Parkinson Disease; Thalamic Nuclei

1992
Effects of dopamine agonists on the spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism.
    Brain research, 1991, Apr-26, Volume: 547, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Basal Ganglia; Dopamine Agents; Electrophysiology; Globus Pallidus; Macaca fascicularis; Motor Activity; Neurons; Parkinson Disease, Secondary; Phenethylamines

1991
Destruction of norepinephrine terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice reduces locomotor activity induced by L-dopa.
    Neuroscience letters, 1991, Feb-25, Volume: 123, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Benzylamines; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Endings; Neurotoxins; Norepinephrine

1991
Differential effects of D1 and D2 agonists in MPTP-treated primates: functional implications for Parkinson's disease.
    Neurology, 1990, Volume: 40, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Behavior, Animal; Benzazepines; Dyskinesia, Drug-Induced; Levodopa; Male; Motor Activity; Oxazines; Parkinson Disease, Secondary; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Saimiri

1990
Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.
    Brain research, 1990, Oct-01, Volume: 528, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Body Weight; Corpus Striatum; Disease Models, Animal; Dopamine; Hydrazines; Levodopa; Male; Methyltyrosines; Mice; Mice, Inbred C57BL; Motor Activity; Parkinson Disease, Secondary; Receptors, Dopamine; Stereotyped Behavior

1990
Preliminary report on adrenal medullary grafting and cografting with sural nerve in the treatment of hemiparkinson monkeys.
    Progress in brain research, 1990, Volume: 82

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Medulla; Animals; Apomorphine; Behavior, Animal; Carbidopa; Caudate Nucleus; Disease Models, Animal; Dopamine; Dyskinesia, Drug-Induced; Levodopa; Macaca mulatta; Motor Activity; Parkinson Disease; Sural Nerve; Transplantation, Heterotopic

1990
Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Brain research, 1989, Sep-18, Volume: 497, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain; Circadian Rhythm; Ditiocarb; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Motor Activity; Reference Values; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1989
Systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine reduces the release of [3H]dopamine from rat striatal slices.
    European journal of pharmacology, 1989, Oct-04, Volume: 169, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholine; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Kinetics; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Spiperone

1989
The effect of prenatal treatment with MPTP or MPP+ on the development of dopamine-mediated behaviors in rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Amphetamines; Animals; Apomorphine; Corpus Striatum; Dopamine; Female; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Stereotyped Behavior

1989
Drug-induced dyskinesia in primates rendered hemiparkinsonian by intracarotid administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Journal of the neurological sciences, 1989, Volume: 90, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dose-Response Relationship, Drug; Ergolines; Injections, Intravenous; Levodopa; Macaca fascicularis; Movement Disorders; Parkinson Disease, Secondary; Pyridines; Quinpirole; Stereotyped Behavior

1989
Behavioral and biochemical effect of chronic treatment with D-1 and/or D-2 dopamine agonists in MPTP monkeys.
    European journal of pharmacology, 1988, May-20, Volume: 150, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Benzazepines; Brain Chemistry; Dopamine; Dyskinesia, Drug-Induced; Female; Homovanillic Acid; Macaca fascicularis; Motor Activity; Parkinson Disease, Secondary; Pyridines; Receptors, Dopamine; Spiperone

1988
Pharmacological effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine receptor system.
    Brain research, 1986, Mar-26, Volume: 369, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Calmodulin; Corpus Striatum; Male; Mice; Motor Activity; Nerve Tissue Proteins; Phosphorylation; Pyridines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Species Specificity

1986
Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Life sciences, 1986, Jul-07, Volume: 39, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Brain; Brain Chemistry; Carbidopa; Carotid Artery, Internal; Disease Models, Animal; Dominance, Cerebral; Dopamine; Homovanillic Acid; Injections, Intra-Arterial; Levodopa; Macaca fascicularis; Movement; Neurons; Parkinson Disease, Secondary; Pyridines

1986
Evidence for the involvement of dopamine agonists and antagonists in duodenal ulcer disease.
    Klinische Wochenschrift, 1986, Volume: 64 Suppl 7

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Brain Chemistry; Cysteamine; Dopamine; Duodenal Ulcer; Gastric Juice; Monoamine Oxidase; Nitriles; Norepinephrine; Pancreatic Juice; Pyridines; Receptors, Dopamine; Secretory Rate; Serotonin; Structure-Activity Relationship

1986
Neurochemical and functional consequences following 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) and methamphetamine.
    Life sciences, 1985, Jan-21, Volume: 36, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Corpus Striatum; Dopamine; Drug Interactions; Female; Male; Methamphetamine; Pargyline; Pyridines; Rats; Rats, Inbred Strains; Serotonin; Species Specificity

1985
Suppression of MPTP-induced dopaminergic neurotoxicity in mice by nomifensine and L-DOPA.
    Brain research, 1985, Sep-09, Volume: 342, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Bromocriptine; Corpus Striatum; Dopamine; Haloperidol; Levodopa; Male; Mice; Mice, Inbred C57BL; Nomifensine; Pyridines

1985
N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects locomotor activity without producing a nigrostriatal lesion in the rat.
    Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Corpus Striatum; Depression, Chemical; Disease Models, Animal; Male; Motor Activity; Neural Pathways; Parkinson Disease; Pyridines; Rats; Rats, Inbred Strains; Substantia Nigra

1984
Neurochemical investigations in vitro with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in preparations of rat brain.
    European journal of pharmacology, 1984, Nov-13, Volume: 106, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholine; Adenylyl Cyclases; Animals; Apomorphine; Brain Chemistry; Cerebral Cortex; Choline; Corpus Striatum; Dopamine; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mitochondria; Monoamine Oxidase; Norepinephrine; Pyridines; Rats; Spiperone

1984
Repeated administration of N-methyl-4-phenyl 1,2,5,6-tetrahydropyridine to rats is not toxic to striatal dopamine neurones.
    Biochemical pharmacology, 1984, Jun-01, Volume: 33, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Apomorphine; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Motor Activity; Neurons; Pyridines; Rats; Rats, Inbred Strains

1984
Behavioral involvement of central dopamine D1 and D2 receptors in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned parkinsonian cynomolgus monkeys.
    Japanese journal of pharmacology, 1995, Volume: 67, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Macaca fascicularis; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2; Sulpiride; Time Factors

1995
CI-1007, a dopamine partial agonist and potential antipsychotic agent. II. Neurophysiological and behavioral effects.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antipsychotic Agents; Apomorphine; Autoreceptors; Avoidance Learning; Basal Ganglia Diseases; Dopamine Agonists; Male; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Saimiri

1995
Selective metabolic activation by apomorphine in striosomes of denervated striatum in MPTP-induced hemiparkinsonian monkeys.
    Neuroreport, 1995, Jun-19, Volume: 6, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Autoradiography; Corpus Striatum; Female; Glucose; Macaca mulatta; Male; Parkinson Disease, Secondary; Receptors, Dopamine

1995
Functional studies on monoaminergic transmitter release in parkinsonism.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Monoamines; Dopamine; Dopamine Agents; Dopamine Antagonists; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Tryptophan

1993
Eye movements in monkeys with local dopamine depletion in the caudate nucleus. I. Deficits in spontaneous saccades.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:1 Pt 2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Caudate Nucleus; Dopamine; Dopamine Agonists; Eye Movements; Injections; Macaca; Male; Reaction Time; Saccades

1995
Effects of dopamine agonists on delayed response performance in chronic low-dose MPTP-treated monkeys.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Conditioning, Operant; Dopamine Agents; Ergolines; Female; Macaca; Male; Methylphenidate; Psychomotor Performance; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2

1994
Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus.
    Journal of neurosurgery, 1994, Volume: 81, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amnion; Animals; Apomorphine; Caudate Nucleus; Cerebral Ventricles; Dopamine; Dopamine beta-Hydroxylase; Fetal Tissue Transplantation; Graft Survival; Macaca mulatta; Motor Activity; Nerve Fibers; Nerve Regeneration; Nucleus Accumbens; Parkinson Disease, Secondary; Putamen; Substantia Nigra; Tyrosine 3-Monooxygenase

1994
Effect of the nigrostriatal dopamine system on acquired neural responses in the striatum of behaving monkeys.
    Science (New York, N.Y.), 1994, Jul-15, Volume: 265, Issue:5170

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Apomorphine; Behavior, Animal; Conditioning, Classical; Corpus Striatum; Dopamine; Haloperidol; Macaca; Male; Neuronal Plasticity; Neurons; Substantia Nigra

1994
Behavioral tolerance to repeated apomorphine administration in parkinsonian monkeys.
    Journal of the neurological sciences, 1993, Volume: 114, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Dopamine; Dopamine Agents; Drug Tolerance; Female; Macaca fascicularis; Male; MPTP Poisoning; Oxazines; Parkinson Disease, Secondary; Psychomotor Performance

1993
The vigilance-promoting drug modafinil counteracts the reduction of tyrosine hydroxylase immunoreactivity and of dopamine stores in nigrostriatal dopamine neurons in the male rat after a partial transection of the dopamine pathway.
    Experimental brain research, 1993, Volume: 93, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Arousal; Benzhydryl Compounds; Biogenic Monoamines; Central Nervous System Stimulants; Corpus Striatum; Dopamine; Dopamine Agents; Male; Modafinil; Nerve Degeneration; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase

1993
The dopamine D1 receptor agonist SKF 38393 suppresses detrusor hyperreflexia in the monkey with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Neuropharmacology, 1993, Volume: 32, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Dopamine Agents; Ergolines; Macaca fascicularis; Male; Parkinson Disease, Secondary; Quinpirole; Reflex; Urinary Bladder; Urination

1993
External and implanted pumps for apomorphine infusion in parkinsonism.
    Acta neurochirurgica. Supplementum, 1993, Volume: 58

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Animals; Apomorphine; Female; Humans; Infusion Pumps, Implantable; Macaca fascicularis; Male; Middle Aged; Motor Activity; Parkinson Disease; Receptors, Dopamine

1993
The neuronal mechanism underlying parkinsonism and dyskinesia, and differential roles of the putamen and caudate nucleus.
    Advances in neurology, 1993, Volume: 60

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Bicuculline; Cats; Caudate Nucleus; Globus Pallidus; Injections, Subcutaneous; Macaca; Motor Skills; Movement Disorders; Neural Pathways; Neurons; Parkinson Disease, Secondary; Picrotoxin; Putamen; Rats; Rats, Wistar; Synaptic Transmission

1993
Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat.
    Neuroscience, 1996, Volume: 74, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Brain Chemistry; Central Nervous System Stimulants; Conditioning, Operant; Dopamine Agonists; Female; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Inbred Strains; Riluzole; Stereotyped Behavior; Substantia Nigra; Sympatholytics; Thiazoles

1996
Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease.
    Synapse (New York, N.Y.), 1997, Volume: 26, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dopamine Agonists; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Oxidopamine; Parkinson Disease, Secondary; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Rotation; Stereotyped Behavior

1997
Differential therapeutic effects of dopamine D1 and D2 agonists in MPTP-induced parkinsonian monkeys: clinical implications.
    European neurology, 1997, Volume: 38 Suppl 1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Benzazepines; Dopamine Agonists; Macaca fascicularis; Parkinson Disease, Secondary; Receptors, Dopamine D1; Receptors, Dopamine D2

1997
The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism.
    Journal of neuroscience methods, 1998, Sep-01, Volume: 83, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Levodopa; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Parkinson Disease, Secondary; Tyrosine 3-Monooxygenase

1998
Apomorphine protects against MPTP-induced neurotoxicity in mice.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Tyrosine 3-Monooxygenase

1999
A new video/computer method to measure the amount of overall movement in experimental animals (two-dimensional object-difference method).
    Journal of neuroscience methods, 1999, Sep-15, Volume: 91, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Callithrix; Computer Storage Devices; Disease Models, Animal; Dopamine Agents; Dopamine Agonists; Image Interpretation, Computer-Assisted; Movement; Parkinson Disease; Time Factors; Video Recording

1999
The pivotal role of iron in NF-kappa B activation and nigrostriatal dopaminergic neurodegeneration. Prospects for neuroprotection in Parkinson's disease with iron chelators.
    Annals of the New York Academy of Sciences, 1999, Volume: 890

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Ferritins; Iron; Lipid Peroxidation; Mice; Nerve Degeneration; NF-kappa B; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Tyrosine 3-Monooxygenase

1999
Endogenous dopaminergic tone and dopamine agonist action.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adamantane; alpha-Methyltyrosine; Animals; Antiparkinson Agents; Apomorphine; Benzopyrans; Callithrix; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Female; Levodopa; Locomotion; Male; Quinpirole; Receptors, Dopamine D1; Receptors, Dopamine D2; Tyrosine 3-Monooxygenase

2000
Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey.
    Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Animals; Apomorphine; Dopamine Agonists; Dyskinesia, Drug-Induced; Female; Globus Pallidus; Macaca fascicularis; Neural Pathways; Neurons; Parkinsonian Disorders; Piribedil; Receptors, Dopamine D1; Receptors, Dopamine D2

2001
Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss.
    Journal of neurochemistry, 2001, Volume: 77, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Binding, Competitive; Catecholamines; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agonists; Glutathione; Glutathione Disulfide; Immunohistochemistry; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Stereoisomerism; Substantia Nigra; Tyrosine 3-Monooxygenase

2001
Gene expression analysis in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease using cDNA microarray: effect of R-apomorphine.
    Journal of neurochemistry, 2001, Volume: 78, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; DNA, Complementary; Dopamine Agents; Gene Expression; In Situ Hybridization; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Parkinson Disease; Parkinson Disease, Secondary; Reverse Transcriptase Polymerase Chain Reaction

2001
Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: evidence from the effects of the alpha(2) adrenoceptor antagonist idazoxan.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Apomorphine; Callithrix; Corpus Striatum; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Globus Pallidus; Idazoxan; Levodopa; Male; Neurologic Examination; Neurons; Norepinephrine; Substantia Nigra

2001
Striatal AMPA receptor binding is unaltered in the MPTP-lesioned macaque model of Parkinson's disease and dyskinesia.
    Experimental neurology, 2002, Volume: 174, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alanine; Animals; Apomorphine; Autoradiography; Binding, Competitive; Corpus Striatum; Disease Models, Animal; Dyskinesia, Drug-Induced; Excitatory Amino Acid Agonists; Female; Ligands; Macaca mulatta; Male; Organ Specificity; Parkinson Disease, Secondary; Pyrimidines; Radioligand Assay; Receptors, AMPA

2002
Continuous subcutaneous infusion of apomorphine rescues nigro-striatal dopaminergic terminals following MPTP injection in mice.
    Neuropharmacology, 2002, Volume: 42, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Corpus Striatum; Dopamine; Dopamine Agents; Infusion Pumps; Injections, Subcutaneous; Mice; Mice, Inbred C57BL; Presynaptic Terminals; Substantia Nigra

2002
Morphological and biochemical evidence that apomorphine rescues striatal dopamine terminals and prevents methamphetamine toxicity.
    Annals of the New York Academy of Sciences, 2002, Volume: 965

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Body Temperature; Catecholamines; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Immunohistochemistry; Kinetics; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Norepinephrine; Serotonin; Tyrosine 3-Monooxygenase

2002
Both short- and long-acting D-1/D-2 dopamine agonists induce less dyskinesia than L-DOPA in the MPTP-lesioned common marmoset (Callithrix jacchus).
    Experimental neurology, 2003, Volume: 179, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Callithrix; Disability Evaluation; Disease Models, Animal; Dopamine Agonists; Dyskinesia, Drug-Induced; Levodopa; Motor Activity; Parkinsonian Disorders; Pergolide; Receptors, Dopamine D1; Receptors, Dopamine D2; Severity of Illness Index

2003
Kinetics of the uptake and distribution of the dopamine D(2,3) agonist (R)-N-[1-(11)C]n-propylnorapomorphine in brain of healthy and MPTP-treated Göttingen miniature pigs.
    Nuclear medicine and biology, 2003, Volume: 30, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Brain; Carbon Radioisotopes; Kinetics; Metabolic Clearance Rate; Parkinsonian Disorders; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Reference Values; Swine, Miniature; Tissue Distribution

2003
A2A antagonist prevents dopamine agonist-induced motor complications in animal models of Parkinson's disease.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Apomorphine; Denervation; Dopamine Agonists; Dyskinesia, Drug-Induced; Levodopa; Macaca fascicularis; Male; Neurons; Oxidopamine; Parkinson Disease, Secondary; Phosphorylation; Purines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Sympatholytics

2003
Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 76, Issue:3-4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Autoradiography; Behavior, Animal; Benzopyrans; Carbidopa; Cocaine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Grooming; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Nerve Tissue Proteins; Oxazines; Pyrroles; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Stereotyped Behavior

2003
Discharge rate of substantia nigra pars reticulata neurons is reduced in non-parkinsonian monkeys with apomorphine-induced orofacial dyskinesia.
    Journal of neurophysiology, 2004, Volume: 92, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dopamine Agents; Dopamine Agonists; Dyskinesia, Drug-Induced; Electrophysiology; Female; Globus Pallidus; Macaca; Neurons; Parkinson Disease, Secondary; Substantia Nigra

2004
Iron and alpha-synuclein in the substantia nigra of MPTP-treated mice: effect of neuroprotective drugs R-apomorphine and green tea polyphenol (-)-epigallocatechin-3-gallate.
    Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Apomorphine; Catechin; Disease Models, Animal; Free Radicals; Iron; Iron Chelating Agents; Lewy Bodies; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Substantia Nigra; Synucleins; Ubiquitin

2004
Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates.
    Experimental neurology, 2005, Volume: 192, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Implants; Dyskinesias; Inflammation; Injections, Subcutaneous; Macaca fascicularis; Male; Movement; Parkinsonian Disorders; Polyvinyls; Recovery of Function; Steroids

2005
Lesions in monkey globus pallidus externus exacerbate parkinsonian symptoms.
    Experimental neurology, 2006, Volume: 199, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Catheter Ablation; Disease Models, Animal; Dopamine Agonists; Globus Pallidus; Macaca mulatta; Movement; Neurons; Parkinson Disease, Secondary

2006
Further validation of LABORAS using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration.
    Journal of neuroscience methods, 2006, Sep-30, Volume: 156, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Animals; Apomorphine; Automation; Behavior, Animal; Benzazepines; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Electrochemistry; Haloperidol; Hyperkinesis; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nerve Degeneration; Psychology, Experimental; Reproducibility of Results; Substantia Nigra

2006
Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:11

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amantadine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Callithrix; Disability Evaluation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced; Female; Grooming; Hallucinations; Levodopa; Parkinsonian Disorders; Psychomotor Agitation; Psychotic Disorders; Statistics, Nonparametric; Stereotyped Behavior

2006
[Responsive changes to MPTP in rats with DAT inhibited by antisense oligonucleotides].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2008, Volume: 25, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dopamine Plasma Membrane Transport Proteins; Immunohistochemistry; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley

2008
Pharmacological MRI (phMRI) monitoring of treatment in hemiparkinsonian rhesus monkeys.
    Cell transplantation, 2008, Volume: 17, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Brain; Female; Glial Cell Line-Derived Neurotrophic Factor; Humans; Macaca mulatta; Magnetic Resonance Imaging; Neurotoxins; Parkinson Disease, Secondary

2008
New evidences for fractalkine/CX3CL1 involved in substantia nigral microglial activation and behavioral changes in a rat model of Parkinson's disease.
    Neurobiology of aging, 2011, Volume: 32, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Antibodies; Antiparkinson Agents; Apomorphine; Chemokine CX3CL1; Disease Models, Animal; DNA Nucleotidylexotransferase; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Levodopa; Male; Mental Disorders; Nerve Tissue Proteins; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reaction Time; Stereotyped Behavior; Substantia Nigra; Tyrosine 3-Monooxygenase

2011
A rotarod test for evaluation of motor skill learning.
    Journal of neuroscience methods, 2010, Jun-15, Volume: 189, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Skills; Nomifensine; Receptors, Dopamine; Rotarod Performance Test; Rotation; Time Factors; Ubiquitin-Protein Ligases

2010
Differing short-term neuroprotective effects of the fibrates fenofibrate and bezafibrate in MPTP and 6-OHDA experimental models of Parkinson's disease.
    Behavioural pharmacology, 2010, Volume: 21, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Apomorphine; Bezafibrate; Cell Count; Disease Models, Animal; Drug Interactions; Exploratory Behavior; Fenofibrate; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; Statistics, Nonparametric; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2010
Microdialysis study of striatal dopamine in MPTP-hemilesioned rats challenged with apomorphine and amphetamine.
    Behavioural brain research, 2010, Dec-20, Volume: 215, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amphetamine; Analysis of Variance; Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Male; Microdialysis; Rats; Rats, Wistar; Stereotyped Behavior; Video Recording

2010
Pharmacologic MRI (phMRI) as a tool to differentiate Parkinson's disease-related from age-related changes in basal ganglia function.
    Neurobiology of aging, 2015, Volume: 36, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Apomorphine; Basal Ganglia; Benzazepines; Diagnosis, Differential; Dopamine Agents; Female; Macaca mulatta; Magnetic Resonance Imaging; Motor Activity; Parkinson Disease, Secondary; Raclopride

2015
Involvement of microRNA-135a-5p in the Protective Effects of Hydrogen Sulfide Against Parkinson's Disease.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3' Untranslated Regions; Animals; Apomorphine; Astrocytes; Base Sequence; Behavior, Animal; Cell Line; Dopamine; Humans; Hydrogen Sulfide; Male; Mice, Inbred C57BL; MicroRNAs; Models, Biological; Neostriatum; Parkinson Disease; Protective Agents; Protein Biosynthesis; rho-Associated Kinases; RNA, Messenger; Rotation

2016
Objectively measuring effects of electro-acupuncture in parkinsonian rhesus monkeys.
    Brain research, 2018, Jan-01, Volume: 1678

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acupuncture Therapy; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Electroacupuncture; Female; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Motor Activity; Motor Cortex; Parkinson Disease; Parkinson Disease, Secondary

2018
Nei-like 1 inhibition results in motor dysfunction and promotes inflammation in Parkinson's disease mice model.
    Biochemical and biophysical research communications, 2020, 01-01, Volume: 521, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Apomorphine; Disease Models, Animal; DNA Glycosylases; Inflammation; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Oxidopamine; Parkinson Disease; Stereotaxic Techniques

2020
Antiparkinsonian activity of Tabebuia impetiginosa bark and biochemical analysis of dopamine in rat brain homogenates.
    Annales pharmaceutiques francaises, 2022, Volume: 80, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adjuvants, Immunologic; Animals; Antioxidants; Antiparkinson Agents; Antipsychotic Agents; Apomorphine; Brain; Catalepsy; Catatonia; Dopamine; Haloperidol; Hypokinesia; Muscle Rigidity; Plant Bark; Rats; Reserpine; Tabebuia; Tremor; Water

2022