aphidicolin glycinate has been researched along with aphidicolin in 5 studies
| Studies (aphidicolin glycinate) | Trials (aphidicolin glycinate) | Recent Studies (post-2010) (aphidicolin glycinate) | Studies (aphidicolin) | Trials (aphidicolin) | Recent Studies (post-2010) (aphidicolin) |
|---|---|---|---|---|---|
| 6 | 1 | 0 | 1,647 | 3 | 136 |
| Protein | Taxonomy | aphidicolin glycinate (IC50) | aphidicolin (IC50) |
|---|---|---|---|
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain KOS | 0.438 | |
| DNA polymerase catalytic subunit | Human alphaherpesvirus 1 strain 17 | 0.5 | |
| DNA polymerase catalytic subunit | Human herpesvirus 5 strain AD169 | 0.4435 | |
| DNA polymerase catalytic subunit | Human herpesvirus 3 strain Dumas | 1.6 | |
| DNA polymerase alpha catalytic subunit | Homo sapiens (human) | 2.98 | |
| DNA polymerase catalytic subunit | Human herpesvirus 6 (strain Uganda-1102) | 0.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, F; D'Incalci, M; Damia, G; Davoli, E; Sessa, C; Tagliabue, G; Zucchetti, M | 1 |
| Califano, R; Cavalli, F; D'Incalci, M; Davoli, E; Frustaci, S; Gumbrell, L; Sessa, C; Sulkes, A; Winograd, B; Zucchetti, M | 1 |
| Dempke, WC; Fichtinger-Schepman, AM; Hill, BT; Shellard, SA | 1 |
| Cysyk, R; Hamilton, TC; Harrison, SD; Moyer, JD; O'Dwyer, PJ; Plowman, J; Suffness, M | 1 |
| Ali-Osman, F; Bigner, DD; Elion, GB; Friedman, HS; Keir, S; Marcelli, S; Moynihan, K | 1 |
1 trial(s) available for aphidicolin glycinate and aphidicolin
| Article | Year |
|---|---|
Phase I and clinical pharmacological evaluation of aphidicolin glycinate.
Topics: Adult; Aged; Antineoplastic Agents; Aphidicolin; Diterpenes; DNA Polymerase II; Drug Administration Schedule; Drug Evaluation; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged | 1991 |
4 other study(ies) available for aphidicolin glycinate and aphidicolin
| Article | Year |
|---|---|
Activity of aphidicolin glycinate alone or in combination with cisplatin in a murine ovarian tumor resistant to cisplatin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Cell Line; Cisplatin; Drug Administration Schedule; Drug Resistance; Drug Synergism; Female; Half-Life; Infusions, Intravenous; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Ovarian Neoplasms | 1992 |
Lack of significant modulation of the formation and removal of platinum-DNA adducts by aphidicolin glycinate in two logarithmically-growing ovarian tumour cell lines in vitro.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Cisplatin; Diterpenes; DNA; DNA Damage; DNA Polymerase II; DNA Repair; Female; Guanine; Humans; Ovarian Neoplasms; Platinum; Tumor Cells, Cultured | 1991 |
Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Cisplatin; Disease Models, Animal; DNA Repair; DNA-Directed DNA Polymerase; Drug Administration Schedule; Drug Resistance; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Ovarian Neoplasms | 1994 |
Enhancement of melphalan activity by inhibition of DNA polymerase-alpha and DNA polymerase-beta.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Aphidicolin; Carmustine; DNA Polymerase I; DNA Polymerase II; Drug Synergism; Enzyme Inhibitors; Female; Guanine; Humans; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Rhabdomyosarcoma; Zalcitabine | 1996 |