aphidicolin and fosmidomycin

aphidicolin has been researched along with fosmidomycin* in 1 studies

Other Studies

1 other study(ies) available for aphidicolin and fosmidomycin

Article	Year
Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis. Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:5 Specific inhibitors of the MVA pathway (pravastatin) and the MEP pathway (fosmidomycin) were used to interfere with the biosynthetic flux which leads to the production of aphidicolin-like diterpene in leaf organ cultures of Scoparia dulcis. Treatment of leaf organs with fosmidomycin resulted in dose dependent inhibition of chlorophylls, carotenoids, scopadulcic acid B (SDB) and phytol production, and no effect on sterol production was observed. In response to the pravastatin treatment, a significant decrease in sterol and perturbation of SDB production was observed. Topics: Anti-Bacterial Agents; Antioxidants; Aphidicolin; Carotenoids; Chlorophyll; Chromatography, Gas; Chromatography, High Pressure Liquid; Diterpenes; Erythritol; Fosfomycin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Photosynthesis; Plant Leaves; Pravastatin; Scoparia; Seeds; Spectrophotometry, Ultraviolet; Sterols; Sugar Phosphates	2006

Article

Year

Involvement of 2-C-methyl-D-erythritol-4-phosphate pathway in biosynthesis of aphidicolin-like tetracyclic diterpene of Scoparia dulcis.

Chemical & pharmaceutical bulletin, 2006, Volume: 54, Issue:5

Specific inhibitors of the MVA pathway (pravastatin) and the MEP pathway (fosmidomycin) were used to interfere with the biosynthetic flux which leads to the production of aphidicolin-like diterpene in leaf organ cultures of Scoparia dulcis. Treatment of leaf organs with fosmidomycin resulted in dose dependent inhibition of chlorophylls, carotenoids, scopadulcic acid B (SDB) and phytol production, and no effect on sterol production was observed. In response to the pravastatin treatment, a significant decrease in sterol and perturbation of SDB production was observed.

Topics: Anti-Bacterial Agents; Antioxidants; Aphidicolin; Carotenoids; Chlorophyll; Chromatography, Gas; Chromatography, High Pressure Liquid; Diterpenes; Erythritol; Fosfomycin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Photosynthesis; Plant Leaves; Pravastatin; Scoparia; Seeds; Spectrophotometry, Ultraviolet; Sterols; Sugar Phosphates

2006