ao-128 and 3-hydroxybutanal

ao-128 has been researched along with 3-hydroxybutanal* in 1 studies

Other Studies

1 other study(ies) available for ao-128 and 3-hydroxybutanal

ArticleYear
Intramolecular direct aldol reactions of sugar diketones: syntheses of valiolamine and validoxylamine G.
    Organic letters, 2008, Sep-18, Volume: 10, Issue:18

    A new and stereoselective intramolecular direct aldol reaction of diketones derived from carbohydrates has been developed to construct carbocycles with D-gluco-, D-galacto-, D-manno-, and L-ido-configurations. The stereochemical outcome of the aldol reaction of the diketone is dependent on the base used. Transformation of D-gluco-aldols readily affords valiolamine which also constitutes a formal synthesis of voglibose. Facile conversion of D-gluco-cyclohexanones into validoxylamine G has been achieved in 12 steps with 15.1% overall yield from D-glucose.

    Topics: Aldehydes; Carbohydrates; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Inositol; Ketones

2008