antofine has been researched along with ipalbidine* in 1 studies
1 other study(ies) available for antofine and ipalbidine
| Article | Year |
|---|---|
Total syntheses of arylindolizidine alkaloids (+)-ipalbidine and (+)-antofine.
This paper presents the first application of two recently developed reactions to natural product synthesis. The first method involves a 6-endo-trig cyclization to prepare a versatile chiral enaminone building block. The second is a direct C-H arylation reaction. As a showcase for the utility of these methods, (+)-antofine and (+)-ipalbidine were synthesized in only 8 steps and 24-26% overall yields. Topics: Indoles; Indolizines; Molecular Structure; Phenanthrolines; Stereoisomerism | 2010 |