antofine has been researched along with carbene* in 2 studies
2 other study(ies) available for antofine and carbene
| Article | Year |
|---|---|
Platinum-catalyzed synthesis of substituted phenanthrenes from biphenyl propargyl alcohols via a carbene intermediate.
An efficient synthesis for phenanthrenes via a Pt-carbene intermediate is described. Using Pt as a catalyst, the readily accessible biphenyl propargyl alcohol substrate can be transformed to the vinylphenanthrene system through a cascade involving electrophilic cyclization, dehydration, and 1,2-H migration. The synthetic utility and efficiency of this protocol were demonstrated via the concise total synthesis of antofine. Topics: Alkynes; Catalysis; Cyclization; Indoles; Methane; Molecular Structure; Phenanthrenes; Phenanthrolines; Platinum Compounds; Propanols | 2014 |
Total synthesis of antofine using the net [5+5]-cycloaddition of gamma,delta-unsaturated carbene complexes and 2-alkynylphenyl ketones as a key step.
A compound containing all of the carbons of the anticancer agent antofine was produced in a single step from the coupling of a gamma,delta-unsaturated carbene complex with a 2-alkynylphenyl ketone derivative. Subsequent conversion to antofine was effected in three steps. Topics: Hydrocarbons; Indoles; Ketones; Methane; Molecular Structure; Phenanthrolines | 2006 |