antipyrine has been researched along with ranitidine in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (31.43) | 18.7374 |
1990's | 1 (2.86) | 18.2507 |
2000's | 13 (37.14) | 29.6817 |
2010's | 9 (25.71) | 24.3611 |
2020's | 1 (2.86) | 2.80 |
Authors | Studies |
---|---|
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Avdeef, A; Tam, KY | 1 |
Akamatsu, M | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Cho, HY; Jeon, YH; Jung, K; Kim, HS; Kim, K; Kim, S; Kwon, NH; Lee, JY; Lee, S; Seo, B; Suh, YG | 1 |
Blaschke, TF; Espiritu-Quiza, MF; Skinner, MH | 1 |
Akamatsu, K; Hirabayashi, Y; Kanaoka, M; Masumoto, S; Nakanishi, K; Nishinobu, M; Ohta, Y; Okada, S; Sakaue, H; Sasaki, T | 1 |
Dicke, JM; Henderson, GI; Johnson, RF; Kuehl, TJ; Schenker, S | 1 |
Kuroiwa, Y; Misawa, S; Nakamura, K; Tanaka, E | 1 |
Crewe, HK; Lennard, MS; Tucker, GT; Woods, HF | 1 |
Clarke, J; Dawson, P | 1 |
Bell, GD; Henry, DA; Kitchingman, G; Langman, MJ; Macdonald, IA | 1 |
de Vries, J; Kather, H; Simon, B; Staiger, C; Walter, E | 1 |
Henry, DA; Langman, MJ | 1 |
Breen, KJ; Bury, R; Desmond, PV; Mashford, ML; Morphett, B; Shaw, RG; Westwood, B | 1 |
Kather, H; Simon, B; Staiger, C; Walter, E | 1 |
Abernethy, DR; Eshelman, FN; Greenblatt, DJ; Shader, RI | 1 |
Iwaki, M; Kawase, A; Tanino, T; Tsuji, A; Uno, S | 1 |
2 trial(s) available for antipyrine and ranitidine
Article | Year |
---|---|
Cimetidine and ranitidine: comparison of effects on hepatic drug metabolism.
Topics: Aminopyrine; Antipyrine; Cimetidine; Furans; Guanidines; Half-Life; Histamine H2 Antagonists; Humans; Microsomes, Liver; Ranitidine | 1980 |
Ranitidine does not impair oxidative or conjugative metabolism: noninteraction with antipyrine, diazepam, and lorazepam.
Topics: Adult; Antipyrine; Biotransformation; Diazepam; Drug Interactions; Humans; Kinetics; Lorazepam; Male; Middle Aged; Random Allocation; Ranitidine | 1984 |
33 other study(ies) available for antipyrine and ranitidine
Article | Year |
---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Lysine-tRNA Ligase; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Molecular Structure; Pyridines; Structure-Activity Relationship | 2021 |
Ranitidine alters antipyrine metabolism in control and phenobarbital-treated mice.
Topics: Animals; Antipyrine; Breath Tests; Cytochrome P-450 Enzyme System; Half-Life; Injections, Intraperitoneal; Liver; Male; Mice; Phenobarbital; Ranitidine | 1990 |
Effects of prolonged oral cimetidine, ranitidine, and famotidine therapy on antipyrine elimination.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antipyrine; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Ranitidine; Thiazoles | 1987 |
A comparative evaluation of the transport of H2-receptor antagonists by the human and baboon placenta.
Topics: Adolescent; Adult; Animals; Antipyrine; Biological Transport; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Nizatidine; Papio; Perfusion; Placenta; Pregnancy; Ranitidine; Thiazoles | 1988 |
The effect of H2-receptor antagonists on antipyrine and pentobarbital metabolism in male and female rats.
Topics: Animals; Antipyrine; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Male; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Ranitidine; Rats; Rats, Inbred Strains; Sex Factors; Thiazoles | 1988 |
Metoprolol oxidation by rat liver microsomes. Inhibition by debrisoquine and other drugs.
Topics: Animals; Antipyrine; Cimetidine; Debrisoquin; Guanidines; Isoquinolines; Metoprolol; Microsomes, Liver; Ranitidine; Rats; Rats, Inbred Strains | 1986 |
A study to evaluate the effect of a course of ranitidine on antipyrine kinetics.
Topics: Adult; Antipyrine; Drug Interactions; Half-Life; Humans; Male; Ranitidine | 1987 |
[Influence of ranitidine on antipyrine metabolism (author's transl)].
Topics: Adult; Antipyrine; Female; Furans; Half-Life; Histamine H2 Antagonists; Humans; Male; Ranitidine; Time Factors | 1980 |
The effects of H2 receptor antagonists on hepatic drug metabolism.
Topics: Adult; Aminopyrine; Antipyrine; Breath Tests; Cimetidine; Furans; Guanidines; Histamine H2 Antagonists; Humans; Liver; Middle Aged; Ranitidine; Structure-Activity Relationship | 1981 |
Effects of cimetidine and ranitidine on hepatic drug metabolism.
Topics: Adult; Antipyrine; Cimetidine; Drug Interactions; Female; Furans; Guanidines; Half-Life; Histamine H2 Antagonists; Humans; Liver; Male; Mixed Function Oxygenases; Ranitidine; Theophylline | 1982 |
Influence of ranitidine on antipyrine pharmacokinetics in healthy volunteers.
Topics: Antipyrine; Drug Interactions; Furans; Humans; Peptic Ulcer; Ranitidine | 1980 |
Decreased intestinal CYP3A and P-glycoprotein activities in rats with adjuvant arthritis.
Topics: Animals; Antipyrine; Arthritis, Experimental; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blotting, Western; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Diffusion Chambers, Culture; Female; Fluorescent Dyes; In Vitro Techniques; Intestinal Mucosa; Intestines; Microsomes; Midazolam; Ranitidine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger | 2007 |