antipyrine and phenobarbital

antipyrine has been researched along with phenobarbital in 163 studies

Research

Studies (163)

Timeframe	Studies, this research(%)	All Research%
pre-1990	134 (82.21)	18.7374
1990's	16 (9.82)	18.2507
2000's	11 (6.75)	29.6817
2010's	2 (1.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Caron, G; Ermondi, G	1
Carrupt, PA; Martel, S; Ottaviani, G	2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC	1
Kirchhof, B; Ohnhaus, EE; Peheim, E	1
Ohnhaus, EE; Park, BK	1
Durrington, PN	1
Breimer, DD; Danhof, M; Krom, DP	1
Pasricha, JS	1
Hildebrandt, AG; Roots, I; Saalfrank, K	1
Lader, MH	1
Albanus, L; Jönsson, M; Sparf, B	1
Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE	1
Clark, CR; Gee, SJ; Krieger, RI; Miller, JL	1
Ilett, KF; McManus, ME	1
Abdul-Rahman, A; Dahlgren, N; Ingvar, M; Rehncrona, S; Siesjö, BK	1
Hepner, GW; Piken, E	1
Streeter, AJ; Timbrell, JA	1
David, A; Flek, J; Frantík, E; Gut, I; Sedivec, V	1
Allemand, H; Bechtel, P; Carayon, P; Deschamps, JP; Gisselbrecht, H; Joanne, C; Miguet, JP; Vuitton, D	1
Aarbakke, J	1
Challiner, MR; Park, BK; Whittaker, AD	1
Curry, S; Lader, M; Loga, S	1
Krieger, RI; Miller, JL; Rorvik, M; Ruebner, BH; Tsao, M	1
Gram, TE; Guarino, AM; Litterst, CL; Mimnaugh, EG; Simon, RC	1
Alvares, AP; Bickers, DR; Bradlow, HL; Kappas, A	1
Kellermann, G; Luyten-Kellermann, M	1
Colombo, JP; Kinser, J; Martin, J; Ohnhaus, EE	1
Bill, P; Buchanan, N; Eyberg, C; Moodley, G	1
Ohnhaus, EE	1
Alvares, AP; Anderson, KE; Kappas, A; Peterson, CM	1
Bekersky, I; Boxenbaum, HG; Cohn, PD; Kaplan, SA; Maggio, AC; Mattaliano, V; Maynard, DE	1
Dixon, MF; Kelleher, J; Losowsky, MS; McLachlan, MS; Walker, BE	1
Barak, AJ; Burnett, DA; Sorrell, MF; Tuma, DJ	1
Branch, RA; Halliwell, M; Jackson, L; Roberts, CJ	2
Reidenberg, MM	1
Harber, MJ; Maddocks, JL; Wake, CJ	1
Aitio, ML; Arvela, P; Bartsch, H; Béréziat, JC; Hietanen, E	1
Natsuhori, M; Van 't Klooster, GA; Van Miert, AS; Witkamp, RF	1
Bammel, A; Kirch, W; Ohnhaus, EE; van der Mee, K	1
Kaka, JS	1
Heidemann, HT; Neumann, U; Ohnhaus, EE; Wensing, G	1
Fischer-Nielsen, A; Hage, E; Hansen, BA; Keiding, S; Poulsen, HE	1
Blaschke, TF; Espiritu-Quiza, MF; Skinner, MH	1
Peterson, EL; Pilla, AM; Popovich, J; Svensson, CK; Zarowitz, BJ	1
Luoma, PV; Marniemi, J; Rautio, A; Sotaniemi, EA; Stengård, J	1
Houston, JB; Matthew, DE	1
Premereur, N; Roels, F; Van den Branden, C	1
Gelboin, HV; Park, SS; Slusher, LB; Vesell, ES	1
Desager, JP; Harvengt, C; Horsmans, Y; Leclercq, V; Van Nieuwenhuyze, Y	1
Karvonen, I; Sotaniemi, EA	1
Loft, S; Poulsen, HE	1
Clerc, JT; Kosmeas, N	1
Breimer, DD; Brugman, M; Schellens, JH; van der Wart, JH	1
Abramson, FP	1
Henderson, DJ; van Bezooijen, CF	1
Aitio, A; Elovaara, E; Engström, K; Hase, T; Häyri, L	1
Breckenridge, AM; Ohnhaus, EE; Park, BK	1
Bachmann, KA; Jahn, D; Schwartz, J; Yang, C	1
Weissel, M	1
Trott, C; Weiss, H	1
Mirvis, DM; Pieper, JA; Rutledge, DR	1
Desager, JP; Harvengt, C; Heller, FR	1
Funae, Y; Imaoka, S; Inoue, K	1
Eksymä, S; Gachalyi, B; Hämäläinen, A; Lahtela, JT; Sotaniemi, EA	1
Korhonen, T; Laakso, M; Laitinen, M; Pyörälä, K; Sarlund, H; Silvasti, M; Uusitupa, M; Voutilainen, E	1
Feely, MP; Hay, A; Mehta, A; Park, BK; Price, DE	1
Døssing, M; Jørgensen, BG; Loft, S; Petersen, KT; Poulsen, HE; Sonne, J	1
Døssing, M; Loft, S; Pilsgaard, H; Poulsen, HE; Rasmussen, B; Sonne, J	1
Kohno, M; Kurata, N; Kuroiwa, Y; Tanaka, E; Yoshida, T	1
Eichelbaum, M; Mineshita, S; Ohnhaus, EE; Zekorn, C	1
Bien, E; Witt, M	1
Bien, E; Gebert, I; Skorka, G	1
Chang, T; Jaffe, JM; Tse, FL	1
Buppodom, P; Koga, N; Yamada, H; Yoshimura, H	1
Datta, DV; Mathur, VS; Narang, AP	2
Kobayashi, S; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H	1
Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H	1
Greene, FE; Page, JG; Passananti, GT; Vesell, ES	1
Passananti, GT; Vessell, ES	1
Bye, A; Chang, R; Conney, AH; Finster, M; Jacobson, M; Kuntzman, R; Munro-Faure, AD; Peck, AW; Poland, A; Poppers, PJ; Welch, R; Wolff, JA	1
Edds, GT; Himes, JA; Shetty, SN	1
Welch, RM	1
Estabrook, RW; Greim, H; Remmer, H; Schenkman, J	1
Burns, JJ	2
Branch, RA; Nies, AS; Shand, DG; Wilkinson, GR	1
Breckenridge, A; Davies, L; Orme, ML	1
Chasseaud, LF; Down, WH; Grundy, RK	1
Kampffmeyer, HG	2
Fouts, JR; Gram, TE; Wilson, JT	1
Hospador, MA; Manthei, RW	1
Grosso, LS; Hospador, MA; Manthei, RW	1
Rawlins, MD; Smith, SE; Taylor, SA	1
Aarbakke, J; Bakke, OM; Bending, M; Davies, DS	1
Ikeda, M; Imamura, T; Otsuji, H	1
Branch, RA; Nies, AS; Shand, DG	1
Jori, A; Pugliatti, C; Santini, V	1
Enna, SJ; Schanker, LS	1
Branch, RA; Herbert, CM; Read, AE	1
Breckenridge, A; Davies, DS; Davies, L; Orme, M	1
Sotaniemi, EA	1
Barnes, JR; Ranta, KE	1
Breckenridge, A; Davies, DS; Ohnhaus, EE; Thorgeirsson, SS	1
Breckenridge, A; Orme, M	1
Page, JG; Vesell, ES	1
Alexanderson, B; Azarnoff, DL; Orrenius, S; Sjoqvist, F; von Bahr, C	1
LeValley, SE; Mitoma, C	1
Schmidt, P; Schulz, KH	1
Dibbern, HW	1
Pelkonen, RO; Puukka, M; Sotaniemi, EA	1
Branch, RA; Herman, RJ	1
Bässmann, H; Böttcher, J; Schüppel, R	1
Vesell, ES	1
Arranto, AJ; Keinänen, K; Kerola, T; Saarni, HU; Sotaniemi, EA; Stengård, JH; Sutinen, S	1
Perlík, F	1
Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF	1
Huang, Y; Li, D; Xu, H; Yang, J; Zhu, H	1
Blouin, RA; Brouwer, KL; Kostenbauder, HB; McNamara, PJ	1
Abramson, FP; Bai, SA; Robinson, D	1
Døssing, M; Pilsgaard, H; Poulsen, HE; Rasmussen, B	1
Chiba, K; Ishizaki, T; Nakagawa, A; Nakamura, K	1
Toftgård, R	1
Breimer, DD; Teunissen, MW; Van Graft, M; Vermeulen, NP	1
Bien, E	1
Kaatz, G; Ohnhaus, EE; Park, BK; Wilson, AC	1
Lavarenne, J; Paire, M	1
Datta, DV; Narang, AP	1
Burger, A; Bürgi, H; Ohnhaus, EE; Studer, H	1
Chiba, K; Ishizaki, T; Nakazawa, Y; Tabuchi, T; Wagatsuma, T	1
Gerber-Taras, E; Ohnhaus, EE; Park, BK	2
Ohnhaus, EE; Studer, H	1
Back, DJ; Breckenridge, AM; Crawford, F; Cross, K; MacIver, M; Orme, ML; Rowe, PH; Smith, E	1
Goldberg, DM	1
Arranto, AJ; Rautio, A; Sotaniemi, EA	1
Larson, RE; Moldowan, MJ; Wilson, VL	1
Boobis, AR; Davies, DS; Kahn, GC; Murray, S	1
Baldauf, J; Büch, HP; Wolff, I	1
Maier-Lenz, H; Ringwelski, L; Windorfer, A	1
Inaba, T; Kalow, W; Lucassen, M	1
Ishizaki, T; Tawara, K	1
Gachályi, B; Renczes, G; Szabó, I	1
Breimer, DD; Groen, K; Jansen, EJ; van Bezooijen, CF	1
Buters, JT; Reichen, J; Zysset, T	1
Advenier, C; Dubor, F; Palette, C; Rovei, V	1
Bachmann, KA; Jauregui, L	1
Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM	1
Hojo, T; Kokue, E; Ohno, R; Shimoda, M	1
ZAKHARIIA, EA; ZAPADNIUK, VI	1
KRISCHEK, J	1
Fujiwara, M; Fukunaga, K; Matsuo, E; Mishima, K; Muto, M; Orito, K; Saito, M	1

Reviews

6 review(s) available for antipyrine and phenobarbital

Article	Year
Drug metabolism in uremia. Clinical nephrology, 1975, Volume: 4, Issue:3 Topics: Acetohexamide; Animals; Antipyrine; Humans; Hydrolysis; Lipid Metabolism; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Rats; Tolbutamide; Uremia; Vitamin D	1975
[Modification of peripheral thyroid hormone metabolism by drugs]. Acta medica Austriaca, 1988, Volume: 15 Suppl 1 Topics: Amiodarone; Antipyrine; Dexamethasone; Heparin; Humans; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Rifampin; Thiouracil; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1988
Utility of clinical chemical determinations of drug concentrations in biological fluids. Clinical chemistry, 1971, Volume: 17, Issue:9 Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays	1971
Effects of environmental chemicals on the metabolism of drugs, carcinogens, and normal body constituents in man. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: 17-Ketosteroids; Alcohols; Androstanes; Animals; Antipyrine; Azo Compounds; Benzopyrenes; Bilirubin; DDT; Dioxoles; Environmental Exposure; Enzyme Induction; Estradiol; Estrone; Ethers; Female; Half-Life; Humans; Hydrocortisone; Infant, Newborn; Male; Metabolism; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Phenylbutazone; Placenta; Polycyclic Compounds; Pregnancy; Rats; Smoking	1971
Hemodynamic drug interactions. Cardiovascular clinics, 1974, Volume: 6, Issue:2 Topics: Animals; Antipyrine; Dogs; Dopamine; Drug Interactions; Enzyme Induction; Glucagon; Half-Life; Hemodynamics; Humans; Lidocaine; Liver Circulation; Macaca mulatta; Metabolic Clearance Rate; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Propranolol; Time Factors	1974
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry. Clinical chemistry, 1980, Volume: 26, Issue:6 Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin	1980

Trials

11 trial(s) available for antipyrine and phenobarbital

Article	Year
Interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man. British journal of clinical pharmacology, 1975, Volume: 2, Issue:3 Topics: Adult; Antipyrine; Chlorpromazine; Clinical Trials as Topic; Drug Interactions; Female; Half-Life; Humans; Male; Orphenadrine; Phenobarbital; Psychotic Disorders	1975
A comparison of three different enzyme inducing agents and their influence on plasma lipids in man [proceedings]. British journal of clinical pharmacology, 1977, Volume: 4, Issue:3 Topics: Antipyrine; Enzyme Induction; Humans; Lipids; Phenobarbital; Rifampin	1977
Glucose tolerance and insulin response to glucose load before and after enzyme inducing therapy in subjects with glucose intolerance and patients with NIDDM having hyperinsulinemia or relative insulin deficiency. Diabetes research (Edinburgh, Scotland), 1989, Volume: 11, Issue:3 Topics: Adult; Antipyrine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Models, Biological; Phenobarbital; Reference Values	1989
The effect of liver microsomal enzyme inducing and inhibiting drugs on insulin mediated glucose metabolism in man. British journal of clinical pharmacology, 1986, Volume: 21, Issue:1 Topics: Adult; Antipyrine; Benzhydryl Compounds; Cimetidine; Enzyme Induction; Enzyme Inhibitors; Female; Glucose; Humans; Insulin; Kinetics; Male; Microsomes, Liver; Phenobarbital	1986
Lack of effect of hepatic enzyme induction on metabolic control in patients with type 2 (non-insulin-dependent) diabetes. Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6 Topics: Adult; Aged; Antipyrine; Diabetes Mellitus, Type 2; Double-Blind Method; Enzyme Induction; Female; Glucose; Humans; Insulin; Lipids; Lipoproteins; Liver; Male; Middle Aged; Phenobarbital; Random Allocation	1987
[Biological half-life of phenacetin and phenazone in man before and after treatment with phenobarbital]. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4 Topics: Acetaminophen; Antipyrine; Clinical Trials as Topic; Half-Life; Humans; Male; Phenacetin; Phenobarbital	1970
Failure to detect increased elimination rate of phenacetin in man after treatment with phenobarbital. Klinische Wochenschrift, 1969, Nov-15, Volume: 47, Issue:22 Topics: Acetaminophen; Adult; Antipyrine; Humans; Male; Phenacetin; Phenobarbital; Time Factors	1969
[Clinical evaluation of analgesics]. Casopis lekaru ceskych, 1984, Jan-20, Volume: 123, Issue:3 Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Phenobarbital	1984
Comparison of in-vivo and in-vitro drug metabolism in patients with Gilbert's syndrome. The Journal of the Association of Physicians of India, 1982, Volume: 30, Issue:6 Topics: Adult; Antipyrine; Bilirubin; Clinical Trials as Topic; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; In Vitro Techniques; Male; Metabolic Clearance Rate; Phenobarbital	1982
The effect of antipyrine, phenobarbitol and rifampicin on thyroid hormone metabolism in man. European journal of clinical investigation, 1981, Volume: 11, Issue:5 Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Male; Microsomes, Liver; Phenobarbital; Rifampin; Thyroid Hormones; Thyrotropin; Thyroxine	1981
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid	1993

Other Studies

146 other study(ies) available for antipyrine and phenobarbital

Article	Year
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13 Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water	2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Drug concentration in saliva. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5 Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide	1978
Effect of enzyme induction on plasma lipids using antipyrine, phenobarbital, and rifampicin. Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:5 Pt 1 Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Cholesterol; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Hydroxylation; Lipids; Lipoproteins; Male; Microsomes, Liver; Phenobarbital; Phospholipids; Rifampin; Triglycerides	1979
Measurement of urinary 6-beta-hydroxycortisol excretion as an in vivo parameter in the clinical assessment of the microsomal enzyme-inducing capacity of antipyrine, phenobarbitone and rifampicin. European journal of clinical pharmacology, 1979, Mar-26, Volume: 15, Issue:2 Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Hydroxylation; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rifampin	1979
Effect of phenobarbitone on plasma apolipoprotein B and plasma high-density-lipoprotein cholesterol in normal subjects. Clinical science (London, England : 1979), 1979, Volume: 56, Issue:5 Topics: Antipyrine; Apolipoproteins; Cholesterol; Female; gamma-Glutamyltransferase; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phenobarbital	1979
Studies on the different metabolic pathways of antipyrine in rats: influence of phenobarbital and 3-methylcholanthrene treatment. Xenobiotica; the fate of foreign compounds in biological systems, 1979, Volume: 9, Issue:11 Topics: Animals; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Half-Life; Kinetics; Male; Methylcholanthrene; Phenobarbital; Rats	1979
Drugs causing fixed eruptions. The British journal of dermatology, 1979, Volume: 100, Issue:2 Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phenacetin; Phenobarbital; Pyridones; Sulfadiazine; Sulfanilamides; Tetracycline	1979
Comparison of methods to study enzyme induction in man. Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00 Topics: 17-Hydroxycorticosteroids; Acetates; Adipates; Adult; Amines; Aminopyrine; Antipyrine; Biotransformation; Clemastine; Enzyme Induction; gamma-Glutamyltransferase; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Phenobarbital; Sugar Acids	1975
[Rational utilization of the major tranquilizers]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:9 Topics: Adult; Antipsychotic Agents; Antipyrine; Chlorpromazine; Drug Interactions; Drug Therapy, Combination; Drug Utilization; Electroencephalography; Half-Life; Humans; Liver; Male; Orphenadrine; Phenobarbital; Psychotic Disorders; Theta Rhythm; Time Factors	1975
Multiple oral doses of diazepam, oxazepam and phenobarbital to dogs--behavioural effects and correlation with antipyrine half-life. Acta pharmacologica et toxicologica, 1977, Volume: 40 Suppl 1, Issue:1 Topics: Administration, Oral; Animals; Antipyrine; Behavior, Animal; Diazepam; Dogs; Drug Evaluation, Preclinical; Half-Life; Male; Oxazepam; Phenobarbital; Time Factors	1977
Use of saliva in therapeutic drug monitoring. Clinical chemistry, 1977, Volume: 23, Issue:2 PT. 1 Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline	1977
Antipyrine plasma half-life. In vivo indicator of oxidative metabolic capability in Rhesus monkeys (Macaca mulatta). Pharmacology, 1978, Volume: 16, Issue:5 Topics: Animals; Antipyrine; Chromatography, Liquid; Half-Life; Haplorhini; Liver; Macaca mulatta; Male; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Time Factors	1978
Comparison of rate of hepatic metabolism in vitro and half-life for antipyrine in vivo in three species. Xenobiotica; the fate of foreign compounds in biological systems, 1979, Volume: 9, Issue:2 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Half-Life; Kinetics; Macropodidae; Male; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Species Specificity	1979
Local versus regional cerebral blood flow in the rat at high (hypoxia) and low (phenobarbital anesthesia) flow rates. Acta physiologica Scandinavica, 1979, Volume: 106, Issue:1 Topics: Anesthesia, General; Animals; Antipyrine; Autoradiography; Carbon Radioisotopes; Cerebrovascular Circulation; Hypoxia; Male; Nitrous Oxide; Partial Pressure; Phenobarbital; Rats; Scintillation Counting	1979
Decreased hepatic microsomal reserve in patients with cirrhosis. Studies using aminopyrine as model drug. The Journal of laboratory and clinical medicine, 1979, Volume: 94, Issue:6 Topics: Adult; Aminopyrine; Antipyrine; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Spironolactone	1979
The effect of dichloralphenazone pretreatment on paracetamol hepatotoxicity in mice. Biochemical pharmacology, 1979, Oct-01, Volume: 28, Issue:19 Topics: Acetaminophen; Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Chloral Hydrate; Cytochrome P-450 Enzyme System; Glutathione; Male; Mice; Mice, Inbred BALB C; Organ Size; Phenobarbital	1979
Influence of phenobarbital on xylene metabolism in man and rats. International archives of occupational and environmental health, 1979, Volume: 44, Issue:2 Topics: Animals; Antipyrine; Humans; Lung; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Rats; Species Specificity; Xylenes	1979
[Hepatic drug metabolism in patients with intrahepatic cholestasis (author's transl)]. Gastroenterologie clinique et biologique, 1979, Volume: 3, Issue:5 Topics: Adolescent; Adult; Aged; Antipyrine; Cholestasis, Intrahepatic; Female; Humans; Liver; Male; Middle Aged; Phenobarbital	1979
Impaired oxidation of antipyrine in stagnant loop rats. Scandinavian journal of gastroenterology, 1977, Volume: 12, Issue:8 Topics: Acetaminophen; Animals; Antipyrine; Biotransformation; Blind Loop Syndrome; Half-Life; Lincomycin; Liver; Male; Phenobarbital; Rats	1977
The effect of enzyme induction on the irreversible binding of ethynyloestradiol to guinea pig liver microsomes. Life sciences, 1978, Dec-18, Volume: 23, Issue:25 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Ethinyl Estradiol; Flavonoids; Guinea Pigs; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rifampin; Spironolactone	1978
Hepatic and metabolic effects of ethanol on rhesus monkeys. Advances in experimental medicine and biology, 1975, Volume: 59 Topics: Animals; Antipyrine; Diet; Endoplasmic Reticulum; Ethanol; Haplorhini; Liver; Macaca mulatta; Mitochondria, Liver; Phenobarbital; Triglycerides	1975
Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice. Journal of toxicology and environmental health, 1975, Volume: 1, Issue:1 Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Aniline Hydroxylase; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Glucuronosyltransferase; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Morphine Derivatives; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxidoreductases; Phenobarbital	1975
Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug. The Journal of clinical investigation, 1977, Volume: 59, Issue:1 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstenes; Antipyrine; Female; Humans; Ketosteroids; Liver; Male; Oxidoreductases; Phenobarbital; Phenylbutazone; Porphyrias; Testosterone	1977
Phenobarbital-induced drug metabolism in man. Toxicology and applied pharmacology, 1977, Volume: 39, Issue:1 Topics: Adolescent; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Enzyme Induction; Female; Half-Life; Humans; Lymphocytes; Male; Phenobarbital	1977
Enzyme induction and renal function in man. British journal of clinical pharmacology, 1977, Volume: 4, Issue:1 Topics: Adult; Alanine Transaminase; Antipyrine; Enzyme Induction; Half-Life; Humans; Kidney; Male; Microsomes, Liver; p-Aminohippuric Acid; Phenobarbital	1977
The metabolism of phenobarbitone, phenytoin and antipyrine in Black patients. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Aug-27, Volume: 52, Issue:10 Topics: Adult; Antipyrine; Black People; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; South Africa	1977
Oxidative drug metabolism and inducibility by phenobarbital in sickle cell anemia. Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 1 Topics: Adolescent; Adult; Anemia, Sickle Cell; Antipyrine; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oxidation-Reduction; Phenobarbital; Phenylbutazone	1977
Influence of phenobarbital on the disposition of clonazepam and antipyrine in the dog. Journal of pharmacokinetics and biopharmaceutics, 1977, Volume: 5, Issue:5 Topics: Animals; Antipyrine; Benzodiazepinones; Clonazepam; Dogs; Drug Interactions; Kinetics; Male; Phenobarbital	1977
Portal venous infusion of paracetamol and antipyrine in the rat. Pharmacological research communications, 1977, Volume: 9, Issue:8 Topics: Acetaminophen; Animals; Antipyrine; Chemical and Drug Induced Liver Injury; Half-Life; Injections, Intravenous; Male; Phenobarbital; Portal Vein; Rats; Spleen	1977
Paradoxical urinary excretion of D-glucaric acid in acute viral hepatitis. Clinical pharmacology and therapeutics, 1976, Volume: 20, Issue:3 Topics: Acute Disease; Antipyrine; Female; Glucaric Acid; Hepatitis A; Humans; Male; Phenobarbital; Sugar Acids	1976
The relationship between liver volume, antipyrine clearance and indocyanine green clearance before and after phenobarbitone administration in man. British journal of clinical pharmacology, 1976, Volume: 3, Issue:5 Topics: Adult; Antipyrine; Biotransformation; Female; Humans; Indocyanine Green; Liver; Liver Function Tests; Male; Phenobarbital; Ultrasonics	1976
Proceedings: The relationships between liver volume and the disposition of antipyrine and indocyanine green before and after phenobarbitone treatment. British journal of pharmacology, 1975, Volume: 55, Issue:2 Topics: Animals; Antipyrine; Indocyanine Green; Liver; Organ Size; Phenobarbital; Rats	1975
The plasma half-life of antipyrine in chromic uraemic and normal subjects. British journal of clinical pharmacology, 1975, Volume: 2, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Enzyme Induction; Female; Half-Life; Humans; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Phenobarbital; Uremia	1975
Drug metabolism in rats with cancer induced by N-nitrosodiethylamine and phenobarbital. Pharmacology & toxicology, 1992, Volume: 70, Issue:6 Pt 1 Topics: Animals; Antipyrine; Debrisoquin; Diethylnitrosamine; Liver; Male; Microsomes, Liver; Neoplasms, Experimental; Organ Size; Phenobarbital; Rats; Rats, Wistar; Stereoisomerism; Warfarin	1992
Metabolism of antipyrine and sulphadimidine in dwarf goats: effects of the enzyme-inducing agents phenobarbital, troleandomycin and rifampicin. Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:11 Topics: Animals; Antipyrine; Biotransformation; Enzyme Induction; Female; Goats; Male; Oxidation-Reduction; Phenobarbital; Rifampin; Sulfamethazine; Troleandomycin	1992
Divergent effects of different enzyme-inducing agents on endogenous and exogenous testosterone. European journal of clinical pharmacology, 1992, Volume: 42, Issue:6 Topics: Adult; Antipyrine; Biotransformation; Enzyme Induction; Gonadotropins, Pituitary; Humans; Male; Microsomes, Liver; Phenobarbital; Rifampin; Testosterone	1992
Concurrent bromosulphophthalein and antipyrine administration to assess liver blood flow and hepatic enzymes in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:6 Topics: Animals; Antipyrine; Drug Administration Schedule; Drug Combinations; Drug Interactions; Injections, Intravenous; Liver; Liver Circulation; Male; Metabolic Clearance Rate; Phenobarbital; Rats; Rats, Inbred Strains; Sulfobromophthalein	1991
Effect of antipyrine and phenobarbital on renal gamma-glutamyltransferase excretion in human urine. Clinical pharmacology and therapeutics, 1990, Volume: 48, Issue:5 Topics: Adolescent; Adult; Antipyrine; Creatinine; Enzyme Induction; gamma-Glutamyltransferase; Humans; Kidney; Male; Microsomes; Phenobarbital	1990
CCl4 cirrhosis in rats: irreversible histological changes and differentiated functional impairment. Journal of hepatology, 1991, Volume: 12, Issue:1 Topics: Animals; Antipyrine; Carbon Tetrachloride; Galactose; Liver; Liver Cirrhosis, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Urea	1991
Ranitidine alters antipyrine metabolism in control and phenobarbital-treated mice. Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:9 Topics: Animals; Antipyrine; Breath Tests; Cytochrome P-450 Enzyme System; Half-Life; Injections, Intraperitoneal; Liver; Male; Mice; Phenobarbital; Ranitidine	1990
Bioimpedance assessment of antipyrine pharmacokinetics before and after enzyme induction. DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:6 Topics: Adult; Antipyrine; Body Composition; Body Weight; Electric Conductivity; Enzyme Induction; Humans; Male; Microsomes, Liver; Models, Biological; Oxidation-Reduction; Phenobarbital; Regression Analysis	1990
High-density lipoprotein subfractions, apolipoproteins and antipyrine clearance in normal subjects. European journal of clinical pharmacology, 1990, Volume: 38, Issue:6 Topics: Adult; Antipyrine; Apolipoproteins; Cholesterol; Cholesterol, HDL; Female; Humans; Lipoproteins, HDL; Male; Phenobarbital; Risk Factors; Triglycerides	1990
Drug metabolizing capacity in vitro and in vivo--II. Correlations between hepatic microsomal monooxygenase markers in phenobarbital-induced rats. Biochemical pharmacology, 1990, Aug-15, Volume: 40, Issue:4 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antipyrine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide	1990
Demonstration of H2O2 production in vivo during aminopyrine metabolism and phenobarbital induction. Archives internationales de physiologie et de biochimie, 1985, Volume: 93, Issue:3 Topics: Aminopyrine; Amitrole; Animals; Antipyrine; Catalase; Cytochrome P-450 Enzyme System; Guinea Pigs; Hydrogen Peroxide; Male; Methanol; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity	1985
Studies on the metabolism of aminopyrine, antipyrine and theophylline using monoclonal antibodies to cytochrome P-450 isozymes purified from rat liver. Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14 Topics: Aminopyrine; Animals; Antibodies, Monoclonal; Antibody Specificity; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Activation; Epitopes; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Theophylline	1987
Influence of rifampicin, phenobarbital and cimetidine on mixed function monooxygenase in extensive and poor metabolizers of debrisoquine. International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:12 Topics: Adult; Antipyrine; Biotransformation; Cimetidine; Debrisoquin; Half-Life; Humans; Hydroxylation; Isoquinolines; Male; Mixed Function Oxygenases; Phenobarbital; Phenotype; Rifampin	1989
Metabolism of metronidazole and antipyrine in isolated rat hepatocytes. Influence of sex and enzyme induction and inhibition. Biochemical pharmacology, 1989, Apr-01, Volume: 38, Issue:7 Topics: Acetates; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Glucuronates; Hydroxides; Isoenzymes; Kinetics; Liver; Male; Methylcholanthrene; Metronidazole; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Sulfates	1989
[A quick DC method for simultaneous quantitative determination of paracetamol, caffeine, phenobarbital and propyphenazone in plasma]. Pharmaceutica acta Helvetiae, 1989, Volume: 64, Issue:1 Topics: Acetaminophen; Antipyrine; Caffeine; Humans; Phenobarbital	1989
Influence of enzyme induction and inhibition on the oxidation of nifedipine, sparteine, mephenytoin and antipyrine in humans as assessed by a "cocktail" study design. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2 Topics: Adult; Antipyrine; Cimetidine; Enzyme Induction; Female; Humans; Hydantoins; Male; Mephenytoin; Metabolic Clearance Rate; Nifedipine; Oxidation-Reduction; Phenobarbital; Smoking; Sparteine	1989
Parallel induction of plasma alpha 1-acid glycoprotein concentration and antipyrine clearance by drugs. Progress in clinical and biological research, 1989, Volume: 300 Topics: Animals; Antipyrine; Chromatography, Gas; Colorimetry; Cytochrome P-450 Enzyme System; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Liver; Male; Metabolic Clearance Rate; Orosomucoid; Phenobarbital; Phenytoin	1989
The effect of age on antipyrine metabolism by liver microsomes isolated from phenobarbital-treated rats. Mechanisms of ageing and development, 1989, Volume: 49, Issue:3 Topics: Aging; Animals; Antipyrine; Male; Microsomes, Liver; Phenobarbital; Rats	1989
Metabolism of antipyrine and m-xylene in rats after prolonged pretreatment with xylene alone or xylene with ethanol, phenobarbital or 3-methylcholanthrene. Xenobiotica; the fate of foreign compounds in biological systems, 1989, Volume: 19, Issue:9 Topics: Administration, Inhalation; Administration, Oral; Animals; Antipyrine; Drug Interactions; Ethanol; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Xylenes	1989
Urinary excretion of 6 beta-hydroxycortisol and the time course measurement of enzyme induction in man. European journal of clinical pharmacology, 1989, Volume: 36, Issue:1 Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Hydrocortisone; Kinetics; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rifampin; Time Factors	1989
The use of single sample clearance estimates to probe hepatic drug metabolism in rats. II. Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:2 Topics: Animals; Antipyrine; Benzoflavones; beta-Naphthoflavone; Clofibrate; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Safrole; Theophylline; Valproic Acid; Warfarin	1988
[The effect of melting temperature and a detergent additive on the melting behavior of propyphenazone-containing suppositories]. Die Pharmazie, 1988, Volume: 43, Issue:1 Topics: Antipyrine; Chemistry, Pharmaceutical; Detergents; Phenobarbital; Suppositories; Surface-Active Agents; Temperature	1988
Effects of chronic phenobarbital on verapamil disposition in humans. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: Adult; Algorithms; Antipyrine; Humans; Male; Phenobarbital; Reference Values; Verapamil	1988
Changes in plasma activities of lipolytic enzymes and lipids of normolipidemic subjects given phenobarbital, a strong microsomal inducer, alone or in combination with fenofibrate. International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:3 Topics: Adult; Antipyrine; Enzyme Induction; Fenofibrate; Humans; Hypolipidemic Agents; Lipase; Lipids; Lipoprotein Lipase; Liver; Male; Microsomes, Liver; Phenobarbital; Phosphatidylcholine-Sterol O-Acyltransferase; Propionates	1988
Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography. Archives of biochemistry and biophysics, 1988, Aug-15, Volume: 265, Issue:1 Topics: Aminopyrine; Ampyrone; Animals; Antipyrine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dipyrone; Female; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazolones; Rats; Rats, Inbred Strains	1988
The effect of low-dose phenobarbitone on three indices of hepatic microsomal enzyme induction. British journal of clinical pharmacology, 1986, Volume: 22, Issue:6 Topics: Adult; Antipyrine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glucaric Acid; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Microsomes, Liver; Phenobarbital	1986
Inhibition and induction of metronidazole and antipyrine metabolism. European journal of clinical pharmacology, 1987, Volume: 32, Issue:1 Topics: Adult; Antipyrine; Cimetidine; Drug Interactions; Female; Humans; Hydroxylation; Kinetics; Male; Metronidazole; Phenobarbital	1987
Effect of concomitant administration of cimetidine and phenobarbital on antipyrine elimination and metabolite formation. International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:4 Topics: Adult; Antipyrine; Biotransformation; Cimetidine; Female; Humans; Male; Phenobarbital	1987
Induction of cytochrome P-450 and related drug-oxidizing activities in muscone (3-methylcyclopentadecanone)-treated rats. Biochemical pharmacology, 1987, Dec-15, Volume: 36, Issue:24 Topics: 5-Aminolevulinate Synthetase; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Antipyrine; Biotransformation; Cycloparaffins; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Trimethadione	1987
The influence of enzyme induction on polymorphic sparteine oxidation. British journal of clinical pharmacology, 1986, Volume: 22, Issue:1 Topics: Adult; Antipyrine; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Middle Aged; Oxidation-Reduction; Phenobarbital; Rifampin; Sparteine	1986
Influence of pyrazolones on hepatic glutathione in rats. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1985, Volume: 8 Topics: 1-Propanol; Acetaminophen; Aminopyrine; Animals; Antipyrine; Carbon Tetrachloride; Cobalt; Female; Glutathione; Liver; Phenobarbital; Propanols; Pyrazoles; Rats; Rats, Inbred Strains; Thioacetamide	1985
Biphasic effect of pyrazolone derivatives on drug-metabolizing enzyme in rat liver. Die Pharmazie, 1985, Volume: 40, Issue:6 Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Dealkylation; Female; Hexobarbital; Liver; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors	1985
Effect of butalbital and phenobarbital pretreatment on antipyrine clearance in the rat. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:2 Topics: Animals; Antipyrine; Barbiturates; Enzyme Induction; Kinetics; Liver; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors	1986
Studies on rat liver cytochrome P-450s involved in the metabolism of antipyrine: phenobarbital- and 3-methylcholanthrene-inducible isozymes possessing 4-hydroxylase activity. Biochemical pharmacology, 1986, Apr-15, Volume: 35, Issue:8 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Isoenzymes; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains	1986
Impairment of drug elimination in patients with liver disease. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:1 Topics: Adult; Antipyrine; Female; Half-Life; Humans; Kinetics; Liver Diseases; Liver Function Tests; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital	1985
The effects of short-term administration of ibuprofen on trimethadione metabolism and antipyrine metabolite formation in the rat. Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:2 Topics: Animals; Antipyrine; Ibuprofen; Liver; Male; Methylcholanthrene; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione	1985
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator. Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9 Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione	1985
Genetic control of drug levels and of the induction of drug-metabolizing enzymes in man: individual variability in the extent of allopurinol and nortriptyline inhibition of drug metabolism. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Adult; Allopurinol; Aniline Compounds; Animals; Antipyrine; Coffee; Cytochromes; Dicumarol; Ethanol; Female; Half-Life; Humans; Kinetics; Male; Mathematics; Metabolism; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Morphinans; Nortriptyline; Oxidoreductases; Pharmacogenetics; Phenobarbital; Phenylbutazone; Pregnancy; Rats; Smoking; Statistics as Topic; Tea; Twins; White People	1971
Enzyme induction in sheep: effects of phenobarbital on in vivo and in vitro drug metabolism. American journal of veterinary research, 1972, Volume: 33, Issue:5 Topics: Anesthesia; Aniline Compounds; Animals; Antipyrine; Cytochromes; Dicumarol; Enzyme Induction; Female; Formaldehyde; Half-Life; Hexobarbital; Metabolic Clearance Rate; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenols; Proteins; Sheep; Sleep; Sulfobromophthalein; Time Factors	1972
Drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs. Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226 Topics: Allopurinol; Animals; Antipyrine; Blood Coagulation; Dicumarol; Dogs; Drug Interactions; Drug Synergism; Enzyme Induction; Half-Life; Liver; Methods; Oxidoreductases; Phenobarbital; Phenylbutazone; Protein Binding; Prothrombin Time; Time Factors; Tolbutamide	1973
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2 Topics: Aniline Compounds; Animals; Antipyrine; Benzopyrenes; Cytochromes; Dicumarol; Electron Transport; Enzyme Induction; Hexobarbital; Kinetics; Liver; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Prothrombin Time	1968
IV. Pharmacogenetics and drug toxicity. Variation of drug metabolism in animals and the prediction of drug action in man. Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2 Topics: Animals; Antipyrine; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cats; Chlordan; Dicumarol; Dogs; Environmental Exposure; Ethyl Biscoumacetate; Glucuronates; Guinea Pigs; Haplorhini; Horses; Humans; Meperidine; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Phenols; Phenylbutazone; Rabbits; Species Specificity; Sulfates	1968
Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow. The Journal of clinical investigation, 1974, Volume: 53, Issue:4 Topics: Animals; Antipyrine; Blood Flow Velocity; Cardiac Output; Enzyme Induction; Half-Life; Haplorhini; Kinetics; Liver; Liver Circulation; Macaca; Male; Metabolic Clearance Rate; Microspheres; Organ Size; Phenobarbital; Propranolol	1974
Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone). Clinical science and molecular medicine, 1974, Volume: 46, Issue:4 Topics: Adolescent; Adult; Animals; Antipyrine; Bilirubin; Glucuronates; Glucuronosyltransferase; Humans; Hyperbilirubinemia, Hereditary; Kinetics; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Proteins; Rats; Uracil Nucleotides	1974
Effect of silybin on the hepatic microsomal drug-metabolising enzyme system in the rat. Arzneimittel-Forschung, 1974, Volume: 24, Issue:12 Topics: Alcohols; Aniline Compounds; Animals; Anisoles; Antipyrine; Binding Sites; Body Weight; Cytochrome P-450 Enzyme System; Flavonoids; Glucuronosyltransferase; Half-Life; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Morphine Derivatives; Nitro Compounds; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Protein Binding; Rats	1974
Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit. The Journal of pharmacology and experimental therapeutics, 1968, Volume: 159, Issue:1 Topics: Aminopyrine; Animals; Antipyrine; Chromatography, Thin Layer; Formaldehyde; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Microsomes; NADP; Oxygen; Phenobarbital; Rabbits; Rats	1968
Influence of age and diet on the induction of hexobarbital-metabolizing enzymes in the mouse. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 128, Issue:1 Topics: Age Factors; Animals; Animals, Newborn; Antipyrine; Benzopyrenes; Biotransformation; Caseins; Diet; Enzyme Induction; Hexobarbital; Histamine H1 Antagonists; Liver; Male; Metronidazole; Mice; Microsomes; Oils; Phenobarbital; Piperazines; Sleep; Starvation; Zea mays	1968
Influence of age and diet on the induction of microsomal enzymes in the mouse. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:3 Topics: Aging; Animals; Antipyrine; Benzopyrenes; Biotransformation; Caseins; Cytochromes; Dietary Proteins; Enzyme Induction; Hexobarbital; Male; Mice; Microsomes, Liver; Phenobarbital; Piperazines; Protein Binding; Proteins; Spectrophotometry; Stimulation, Chemical; Ultracentrifugation	1971
Spironolactone--a weak enzyme inducer in man. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:7 Topics: Adult; Antipyrine; Biotransformation; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Liver; Male; Phenobarbital; Spironolactone	1972
14C-antipyrine as a model compound in the study of drug oxidation and enzyme induction in individual surviving rats. Acta pharmacologica et toxicologica, 1974, Volume: 35, Issue:2 Topics: Animals; Antipyrine; Carbon Radioisotopes; Chromatography, Thin Layer; Enzyme Induction; Half-Life; Male; Methods; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry; Stimulation, Chemical; Time Factors	1974
Comparative studies on hepatic N- and O-demethylation. Japanese journal of pharmacology, 1972, Volume: 22, Issue:4 Topics: Aniline Compounds; Animals; Anisoles; Antipyrine; Benzene; Biotransformation; Depression, Chemical; Ethylamines; Female; Hydroxylation; Kinetics; Liver; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Pyridines; Rats; Stimulation, Chemical; Tolbutamide	1972
Differences in microsomal enzyme induction between Sprague-Dawley and Long-Evans rats. Pharmacology, 1972, Volume: 7, Issue:5 Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Antipyrine; Brain Chemistry; DDT; Enzyme Induction; Eucalyptus; Female; Liver; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Sleep	1972
Absorption of drugs from the rat lung. The American journal of physiology, 1972, Volume: 223, Issue:5 Topics: Absorption; Aminohippuric Acids; Aniline Compounds; Animals; Antipyrine; Diffusion; Intestinal Absorption; Lung; Male; Pentobarbital; Permeability; Pharmaceutical Preparations; Phenobarbital; Procainamide; Pulmonary Alveoli; Rats; Salicylates; Sulfonic Acids; Tetraethylammonium Compounds	1972
Determinants of serum antipyrine half-lives in patients with liver disease. Gut, 1973, Volume: 14, Issue:7 Topics: Adult; Alkaline Phosphatase; Antipyrine; Aspartate Aminotransferases; Bilirubin; Half-Life; Hepatitis; Humans; Hypoproteinemia; Hypoprothrombinemias; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Microsomes, Liver; Middle Aged; Phenobarbital; Prednisone; Prothrombin; Serum Albumin	1973
Dose-dependent enzyme induction. British journal of pharmacology, 1973, Volume: 47, Issue:3 Topics: Amobarbital; Animals; Antipyrine; Dose-Response Relationship, Drug; Enzyme Induction; Half-Life; Humans; Microsomes, Liver; Morphinans; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Secobarbital; Sleep; Warfarin	1973
Effects of drug pretreatment on antipyrine levels in blood and tissues: an example of multiple drug interactions. Pharmacology, 1973, Volume: 10, Issue:5 Topics: Animals; Antipyrine; Brain; Brain Chemistry; Drug Interactions; Enzyme Induction; Half-Life; Kinetics; Liver; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Time Factors	1973
Interaction of environmental agents and drugs. Environmental research, 1969, Volume: 2, Issue:5 Topics: Animals; Anticoagulants; Antipyrine; Benzopyrenes; Chlordan; DDT; Dogs; Environment; Environmental Exposure; Enzyme Induction; Haplorhini; Humans; Male; Microsomes, Liver; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Toxicology; Zoxazolamine	1969
The metabolism of dimethylformamide and dimethylacetamide. Toxicology and applied pharmacology, 1972, Volume: 23, Issue:2 Topics: Acetamides; Animals; Antipyrine; Chromatography, Gas; Chromatography, Thin Layer; Dimethylformamide; Enzyme Induction; In Vitro Techniques; Liver; Male; Mass Spectrometry; Methylation; Phenobarbital; Rats; Spectrophotometry, Infrared	1972
Changes in liver blood flow during enzyme induction. Biochemical pharmacology, 1971, Volume: 20, Issue:10 Topics: Animals; Antipyrine; Benzopyrenes; Cytochromes; Dealkylation; Enzyme Induction; In Vitro Techniques; Liver Circulation; Male; Microsomes, Liver; Morphinans; Oxidoreductases; Pentobarbital; Phenobarbital; Rats; Sleep; Stimulation, Chemical	1971
Clinical implications of enzyme induction. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Alcohols; Amobarbital; Animals; Antipyrine; Benzazepines; Blood Coagulation; Chloral Hydrate; Chlordiazepoxide; Enzyme Induction; Ethanol; Fluorometry; Half-Life; Humans; Hydrocortisone; Hypnotics and Sedatives; Ketones; Kinetics; Male; Metabolism; Microsomes, Liver; Morphinans; Nitro Compounds; Paralysis; Phenobarbital; Rats; Rheumatic Heart Disease; Secobarbital; Sleep; Time Factors; Warfarin	1971
Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man. The Journal of clinical investigation, 1969, Volume: 48, Issue:12 Topics: Adult; Alcohol Drinking; Antipyrine; Coffee; Female; Genetics, Medical; Humans; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Pregnancy; Smoking; Tea; Twins	1969
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats. European journal of pharmacology, 1970, Volume: 9, Issue:1 Topics: Animals; Antipyrine; Desipramine; Enzyme Induction; In Vitro Techniques; Liver; Male; Nortriptyline; Perfusion; Phenobarbital; Phenylbutazone; Rats; Tremorine	1970
Effect on newborn rats of perinatal exposure to phenobarbital. Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 187, Issue:1 Topics: Acetaminophen; Animals; Animals, Newborn; Antipyrine; Brain; Female; Hexobarbital; Microsomes, Liver; Nitrophenols; Phenobarbital; Pregnancy; Pyrazoles; Rats; Sleep; Spectrophotometry	1970
[Fixed exanthema due to 3 different drugs with separate localization. Contribution to the problem of barbiturate allergy]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Jul-15, Volume: 42, Issue:14 Topics: Antipyrine; Barbiturates; Drug Hypersensitivity; Exanthema; Female; Humans; Middle Aged; Phenobarbital; Phenolphthaleins; Skin Tests	1967
[On the resportion profile of drugs. 2. On studies with the resorption model]. Arzneimittel-Forschung, 1966, Volume: 16, Issue:10 Topics: Absorption; Antipyrine; Aspirin; Codeine; Hydrogen-Ion Concentration; Models, Biological; Phenacetin; Phenobarbital; Tolbutamide	1966
Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays. European journal of clinical pharmacology, 1980, Volume: 17, Issue:4 Topics: Adult; Aged; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; Hepatitis; Histamine H1 Antagonists; Humans; Liver; Liver Cirrhosis; Male; Medroxyprogesterone; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Prednisolone; Rifampin	1980
Enzyme induction and beta-adrenergic receptor blocking drugs. British journal of clinical pharmacology, 1984, Volume: 17 Suppl 1 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antipyrine; Drug Interactions; Enzyme Induction; Half-Life; Humans; Kinetics; Middle Aged; Phenobarbital; Propranolol; Rifampin; Smoking	1984
Quantitation of norantipyrine sulphate and norantipyrine glucuronide as major metabolites of antipyrine in man and rat. The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:6 Topics: Adult; Animals; Antipyrine; Chromatography, Thin Layer; Edaravone; Glucuronates; Humans; Hydrolysis; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Solubility; Sulfates	1984
Complex, dynamically interacting host factors that affect the disposition of drugs and carcinogens. IARC scientific publications, 1982, Issue:39 Topics: Animals; Antipyrine; Carcinogens; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Enzyme Induction; Fasting; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnancy; Rats; Twins	1982
Hepatic glucose-6-phosphatase activity in non-insulin dependent diabetics. Effect of enzyme-inducing drugs. Acta medica Scandinavica, 1984, Volume: 215, Issue:4 Topics: Aged; Antipyrine; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Enzyme Induction; Female; Glipizide; Glucose-6-Phosphatase; Humans; Liver; Liver Glycogen; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Middle Aged; Phenobarbital	1984
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients. British journal of clinical pharmacology, 1984, Volume: 18, Issue:3 Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid	1984
[Effect of anti-arrhythmia agent, gallanilide, on hepatic drug metabolizing enzymes in rats]. Yao xue xue bao = Acta pharmaceutica Sinica, 1984, Volume: 19, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Antipyrine; Gallic Acid; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains	1984
Phenobarbital in the genetically obese Zucker rat. II. In vivo and in vitro assessments of microsomal enzyme induction. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Male; Metabolic Clearance Rate; Microsomes, Liver; Obesity; Phenobarbital; Rats; Rats, Inbred Strains; Rats, Zucker	1984
Relationships between propranolol plasma protein binding, glycoprotein concentration, and enzyme induction following phenobarbital administration in the dog. Biochemical pharmacology, 1983, Sep-01, Volume: 32, Issue:17 Topics: Animals; Antipyrine; Blood Proteins; Cytochrome P-450 Enzyme System; Dogs; Glycoproteins; Half-Life; Kinetics; Male; Orosomucoid; Phenobarbital; Propranolol	1983
Time course of phenobarbital and cimetidine mediated changes in hepatic drug metabolism. European journal of clinical pharmacology, 1983, Volume: 25, Issue:2 Topics: Adult; Aminopyrine; Antipyrine; Biotransformation; Breath Tests; Cimetidine; Female; Half-Life; Humans; Liver; Male; Phenobarbital	1983
Influence of cigarette smoke on antipyrine metabolite formation in rats. Research communications in chemical pathology and pharmacology, 1983, Volume: 41, Issue:3 Topics: Animals; Antipyrine; Biotransformation; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Smoking	1983
Effects of xylene exposure on the metabolism of antipyrine in vitro and in vivo in the rat. Toxicology, 1983, Volume: 28, Issue:1-2 Topics: Animals; Antipyrine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Kinetics; Male; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Xylenes	1983
Influence of allylisopropylacetamide and phenobarbital treatment on in vivo antipyrine metabolite formation in rats. Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:8 Topics: Acetamides; Allylisopropylacetamide; Animals; Antipyrine; Biotransformation; Half-Life; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors	1983
[Effect of pyrazolone derivatives on the level of reduced glutathione in rat liver]. Biomedica biochimica acta, 1983, Volume: 42, Issue:5 Topics: Aminopyrine; Animals; Antipyrine; Cobalt; Female; Glutathione; Liver; Male; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains	1983
Enzyme induction by phenobarbitone and vitamin K1 disposition in man. British journal of clinical pharmacology, 1984, Volume: 18, Issue:1 Topics: Antipyrine; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Vitamin K 1	1984
[Drug interactions with macrolids compared action of two macrolids on liver microsomal activity ]. Pathologie-biologie, 1982, Volume: 30, Issue:6 Pt 2 Topics: Adult; Anti-Bacterial Agents; Antipyrine; Drug Interactions; Female; Humans; Kinetics; Leucomycins; Male; Microsomes, Liver; Phenobarbital; Troleandomycin	1982
Antipyrine disposition in relation to lowered anticonvulsant plasma level during pregnancy. Obstetrics and gynecology, 1982, Volume: 60, Issue:5 Topics: Adult; Anticonvulsants; Antipyrine; Delivery, Obstetric; Dose-Response Relationship, Drug; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Postpartum Period; Pregnancy; Pregnancy Complications; Time Factors; Valproic Acid	1982
Enzyme-inducing drug combinations and their effects on liver microsomal enzyme activity in man. European journal of clinical pharmacology, 1983, Volume: 24, Issue:2 Topics: Adult; Antipyrine; Drug Combinations; Enzyme Induction; Female; Humans; Hydrocortisone; Male; Microsomes, Liver; Phenobarbital; Rifampin	1983
A link between liver microsomal enzyme activity and thyroid hormone metabolism in man. British journal of clinical pharmacology, 1983, Volume: 15, Issue:1 Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rifampin; Thyroid Hormones	1983
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids. Ciba Foundation symposium, 1980, Volume: 76 Topics: Animals; Antipyrine; Contraceptives, Oral; Environment; Ethinyl Estradiol; Female; Half-Life; Humans; Intestinal Mucosa; Jejunum; Kinetics; Norethindrone; Norgestrel; Phenobarbital; Rats; Rifampin	1980
Pericellular collagen in alcoholics with liver cirrhosis. Research communications in chemical pathology and pharmacology, 1982, Volume: 35, Issue:1 Topics: Adult; Antipyrine; Collagen; Humans; Liver; Liver Cirrhosis, Alcoholic; Male; Medroxyprogesterone; Metabolic Clearance Rate; Middle Aged; Phenobarbital	1982
A non-invasive method for the study of hepatic drug metabolism in rodents: antineoplastic drug effects on antipyrine metabolism in mice. Chemico-biological interactions, 1982, Volume: 40, Issue:2 Topics: Aminopyrine; Animals; Antineoplastic Agents; Antipyrine; Carmustine; Half-Life; Liver; Male; Mice; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Saliva	1982
Impairment of hepatic drug metabolism in patients with Budd-Chiari syndrome. The Indian journal of medical research, 1982, Volume: 75 Topics: Adolescent; Adult; Antipyrine; Budd-Chiari Syndrome; Female; Half-Life; Humans; Inactivation, Metabolic; Liver; Liver Function Tests; Male; Middle Aged; Phenobarbital	1982
Differential effects of 3-methylcholanthrene and phenobarbitone treatment on the oxidative metabolism of antipyrine in vitro by microsomal fractions of rat liver. Xenobiotica; the fate of foreign compounds in biological systems, 1982, Volume: 12, Issue:8 Topics: Animals; Antipyrine; Biotransformation; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains	1982
[Drug distribution during convulsive seizure in comparison with narcosis]. Arzneimittel-Forschung, 1980, Volume: 30, Issue:12 Topics: Adipose Tissue; Animals; Antipyrine; Brain; Female; Liver; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Spleen	1980
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)]. Arzneimittel-Forschung, 1981, Volume: 31, Issue:1 Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets	1981
The estimation of 6 beta-hydroxycortisol in urine -- a comparison of two methods: high performance liquid chromatography and radioimmunoassay. Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1981, Volume: 19, Issue:8 Topics: Antipyrine; Chromatography, High Pressure Liquid; Humans; Hydrocortisone; Phenobarbital; Radioimmunoassay; Rifampin	1981
Antipyrine metabolism in the rat by three hepatic monooxygenases. Life sciences, 1980, Jun-09, Volume: 26, Issue:23 Topics: Animals; Antipyrine; Drug Stability; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Sex Factors; Time Factors	1980
Absence of changes in drug disposition and catecholamine sensitivity in the hyperthyroid dog. British journal of pharmacology, 1980, Volume: 71, Issue:1 Topics: Animals; Antipyrine; Catecholamines; Dogs; Female; Heart Rate; Hyperthyroidism; Kinetics; Male; Pharmaceutical Preparations; Phenobarbital; Propranolol	1980
The effect of combined pre-treatment on the metabolism of antipyrine in the rat. Acta physiologica Hungarica, 1995, Volume: 83, Issue:1 Topics: Animals; Antipyrine; Enzyme Activation; Half-Life; Kinetics; Male; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Wistar; Spironolactone	1995
The influence of aging on the metabolism of simultaneously administered hexobarbital enantiomers and antipyrine before and after phenobarbital induction in male rats: a longitudinal study. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2 Topics: Aging; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Longitudinal Studies; Male; Metabolic Clearance Rate; Phenobarbital; Rats; Rats, Inbred BN; Stereoisomerism	1994
Metabolism of antipyrine in vivo in two rat models of liver cirrhosis. Its relationship to intrinsic clearance in vitro and microsomal membrane lipid composition. Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6 Topics: Animals; Antipyrine; Bile Acids and Salts; Breath Tests; Carbon Tetrachloride; Lipids; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Membrane Fluidity; Microsomes, Liver; Models, Biological; Organ Size; Phenobarbital; Rats; Rats, Sprague-Dawley; Saliva	1993
Determination of antipyrine sulphoconjugates in isolated cultured rat hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:2 Topics: Animals; Antipyrine; Cells, Cultured; Chromatography; Drug Stability; Liver; Male; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Solvents; Sulfates	1993
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:11 Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin	1996
Enzyme and plasma protein induction by multiple oral administrations of phenobarbital at a therapeutic dosage regimen in dogs. Journal of veterinary pharmacology and therapeutics, 2002, Volume: 25, Issue:2 Topics: Administration, Oral; Animals; Anticonvulsants; Antipyrine; Cytochrome P-450 Enzyme System; Dogs; Drug Administration Schedule; Enzyme Induction; Male; Microsomes, Liver; Orosomucoid; Phenobarbital	2002
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS]. Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57 Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology	1964
[Migraine therapy with migraine kranit]. Die Medizinische Welt, 1951, Sep-15, Volume: 20, Issue:37 Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital	1951
Long-lasting enhancement of CYP activity after discontinuation of repeated administration of phenobarbital in dogs. Research in veterinary science, 2009, Volume: 87, Issue:3 Topics: Animals; Anticonvulsants; Antipyrine; Area Under Curve; Cytochrome P-450 Enzyme System; Dogs; Drug Administration Schedule; Enzyme Activation; Half-Life; Liver; Phenobarbital	2009