antipyrine and oxazepam

antipyrine has been researched along with oxazepam in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's5 (20.83)18.2507
2000's10 (41.67)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghuloum, AM; Jain, AN; Sage, CR1
Coassolo, P; Lavé, T; Schneider, G1
Ertl, P; Rohde, B; Selzer, P1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Albanus, L; Jönsson, M; Sparf, B1
Kellermann, GH; Luyten-Kellermann, M1
Andreasen, F; Andreasen, PB; Døssing, M; Loft, S; Sonne, J1
Dorfeldt, A; Hamberg, O; Loft, S; Ovesen, L; Sonne, J1
Andreasen, F; Dragsted, J; Døssing, M; Loft, S; Sonne, J1
Denke, M; Inturrisi, CE; Wissel, PS1
Benzi, G; Berté, F; Crema, A1
Mascherpa, P1
Andersen, V; Larsen, S; Sonne, J1
Blanchard, N; Coassolo, P; Hewitt, NJ; Jones, H; Lavé, T; Silber, P1

Trials

2 trial(s) available for antipyrine and oxazepam

ArticleYear
The effect of dietary energy and protein deficiency on drug metabolism.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:6

    Topics: Adult; Antipyrine; Biotransformation; Body Weight; Diet; Energy Metabolism; Glucuronates; Humans; Male; Metronidazole; Oxazepam; Oxidation-Reduction; Pharmaceutical Preparations; Protein Deficiency; Saliva

1990
Antipyrine, oxazepam, and indocyanine green clearance in patients with chronic pancreatitis and healthy subjects.
    Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chronic Disease; Coloring Agents; Female; GABA Modulators; Humans; Inactivation, Metabolic; Indocyanine Green; Male; Middle Aged; Models, Biological; Oxazepam; Pancreatitis; Statistics, Nonparametric

1999

Other Studies

22 other study(ies) available for antipyrine and oxazepam

ArticleYear
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
    Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10

    Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship

1999
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
    Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20

    Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results

2000
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Multiple oral doses of diazepam, oxazepam and phenobarbital to dogs--behavioural effects and correlation with antipyrine half-life.
    Acta pharmacologica et toxicologica, 1977, Volume: 40 Suppl 1, Issue:1

    Topics: Administration, Oral; Animals; Antipyrine; Behavior, Animal; Diazepam; Dogs; Drug Evaluation, Preclinical; Half-Life; Male; Oxazepam; Phenobarbital; Time Factors

1977
On the regulation of antipyrine and oxazepam metabolism in man.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 23, Issue:2

    Topics: Antipyrine; Biotransformation; Female; Glucuronates; Half-Life; Humans; Male; Oxazepam

1979
Glucuronidation of oxazepam is not spared in patients with hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6

    Topics: Absorption; Adult; Antipyrine; Female; Glucuronates; Hepatic Encephalopathy; Humans; Male; Osmolar Concentration; Oxazepam

1990
Influence of a very low calorie diet on the clearance of oxazepam and antipyrine in man.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:4

    Topics: Adult; Antipyrine; Body Weight; Chromatography, High Pressure Liquid; Diet, Reducing; Energy Intake; Female; Humans; Middle Aged; Obesity; Oxazepam

1989
A comparison of the effects of a macrobiotic diet and a Western diet on drug metabolism and plasma lipids in man.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:4

    Topics: Adult; Antipyrine; Body Weight; Cholesterol; Diet; Humans; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Methadone; Oxazepam; Pharmaceutical Preparations

1987
Investigation of hepatic drug metabolism by isolated perfused liver in situ.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:7

    Topics: Aminopyrine; Animals; Antipyrine; Dogs; Extracorporeal Circulation; Haplorhini; Liver; Oxazepam; Perfusion; Tranquilizing Agents

1967
[Aspects of iatrogenic pharmacology and toxicology at the fetal level].
    Minerva ginecologica, 1969, Sep-30, Volume: 21, Issue:18

    Topics: Aminopyrine; Amitriptyline; Animals; Anti-Bacterial Agents; Antipyrine; Diazepam; Dogs; Female; Fetal Diseases; Fetus; Glucuronates; Humans; Iatrogenic Disease; Oxazepam; Pregnancy; Rabbits; Rats; Tranquilizing Agents

1969
Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:5

    Topics: Antipyrine; Bosentan; Cell Culture Techniques; Cryopreservation; Hepatocytes; Humans; Kinetics; Metabolic Clearance Rate; Models, Biological; Monte Carlo Method; Oxazepam; Pharmaceutical Preparations; Protein Binding; Reproducibility of Results; Serum; Sulfonamides

2006