antipyrine and nicotine

antipyrine has been researched along with nicotine in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (29.03)	18.7374
1990's	2 (6.45)	18.2507
2000's	14 (45.16)	29.6817
2010's	6 (19.35)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Caron, G; Ermondi, G	1
Jolivette, LJ; Ward, KW	1
Carrupt, PA; Martel, S; Ottaviani, G	2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Breckenridge, AM; Ohnhaus, EE; Park, BK	1
Jusko, WJ	1
Klatzo, I; Nowak, TS; Tomida, S; Wagner, HG	1
Ask, P; Michel, ME; Oberg, PA; Rapoport, SI; Rundquist, I; Smith, QR	1
Page, JG; Vesell, ES	1
Oldendorf, WH	1
Chinard, FP; Effros, RM	1
Kamat, UG; Pradhan, RJ; Sheth, UK	1
Dawson, GW; Vestal, RE	1
Acuff, V; Bereczki, D; Chen, JL; Fenstermacher, JD; Ghersi-Egea, JF; Hans, FJ; Otsuka, T; Patlak, C; Wei, L	1
Chance, MB; Goddijn-Wessel, TA; Hemontolor, ME; Sastry, BV	1
Ahmed, MS; Hankins, GD; Keyler, DE; Nanovskaya, TN; Nekhayeva, IA; Pentel, PR	1
Auriola, S; Halonen, T; Karttunen, V; Myllynen, P; Myöhänen, K; Vähäkangas, K; Veid, J	1

Reviews

3 review(s) available for antipyrine and nicotine

Article	Year
[Modification of the action of drugs by inhibition of their metabolism]. Recenti progressi in medicina, 1979, Volume: 67, Issue:3 Topics: Antipyrine; Barbiturates; Drug Interactions; Enzyme Induction; Enzyme Repression; Ethanol; gamma-Glutamyltransferase; Glucaric Acid; Humans; Nicotine; Pharmaceutical Preparations; Pharmacology; Phenytoin; Rifampin	1979
Role of tobacco smoking in pharmacokinetics. Journal of pharmacokinetics and biopharmaceutics, 1978, Volume: 6, Issue:1 Topics: Animals; Antipyrine; Cadmium; Carbon Monoxide; Cyanides; Drug Interactions; Humans; Kinetics; Nicotine; Pesticides; Pharmaceutical Preparations; Phenacetin; Polycyclic Compounds; Smoking; Xanthines	1978
Smoking and drug metabolism. Pharmacology & therapeutics, 1981, Volume: 15, Issue:2 Topics: Antipyrine; Carbon Monoxide; Cyanides; Humans; Nicotiana; Nicotine; Pesticides; Pharmaceutical Preparations; Plants, Toxic; Polycyclic Compounds; Smoke; Smoking; Trace Elements	1981

Other Studies

28 other study(ies) available for antipyrine and nicotine

Article	Year
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability. Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13 Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water	2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Effect of acute electrode placement on regional CBF in the gerbil: a comparison of blood flow measured by hydrogen clearance, [3H]nicotine, and [14C]iodoantipyrine techniques. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:1 Topics: Animals; Antipyrine; Cerebrovascular Circulation; Electrodes; Female; Gerbillinae; Hydrogen; Methods; Nicotine	1989
Sciatic nerve blood flow measured by laser Doppler flowmetry and [14C]iodoantipyrine. The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 2 Topics: Animals; Antipyrine; Autoradiography; Blood Pressure; Carbon Radioisotopes; Cobalt Radioisotopes; Male; Microspheres; Nicotine; Rats; Regional Blood Flow; Rheology; Sciatic Nerve; Tritium; Ultrasonography	1985
Genetic control of dicumarol levels in man. The Journal of clinical investigation, 1968, Volume: 47, Issue:12 Topics: Adult; Antipyrine; Caffeine; Centrifugation; Coffee; Dicumarol; Female; Genetics, Medical; Humans; Male; Methylcholanthrene; Middle Aged; Nicotine; Phenylbutazone; Pregnancy; Prothrombin Time; Smoking; Spectrophotometry; Twins	1968
Brain uptake of metabolites and drugs following carotid arterial injections. Transactions of the American Neurological Association, 1971, Volume: 96 Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats	1971
The in vivo pH of the extravascular space of the lung. The Journal of clinical investigation, 1969, Volume: 48, Issue:11 Topics: Amines; Aniline Compounds; Animals; Antipyrine; Atropine; Carbon Dioxide; Dogs; Dye Dilution Technique; Guanidines; Histamine; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Ketones; Lung; Mathematics; Mescaline; Morphine; Nicotine; Oxyphenbutazone; Partial Pressure; Quinine; Radioisotope Dilution Technique; Tritium	1969
Potentiation of a non-narcotic analgesic, dipyrone, by cholinomimetic drugs. Psychopharmacologia, 1972, Volume: 23, Issue:2 Topics: Animals; Antipyrine; Atropine; Carbachol; Dextroamphetamine; Drug Antagonism; Drug Synergism; Female; Male; Methylamines; Mice; Neostigmine; Nicotine; Physostigmine; Pilocarpine; Sulfonic Acids; Sympathomimetics; Tremorine	1972
Nicotine raises the influx of permeable solutes across the rat blood-brain barrier with little or no capillary recruitment. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:4 Topics: 3-O-Methylglucose; Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Blood-Brain Barrier; Capillaries; Capillary Permeability; Cerebrovascular Circulation; Erythrocyte Count; Kinetics; Male; Methylglucosides; Nicotine; Rats; Rats, Sprague-Dawley; Serum Albumin, Radio-Iodinated	1995
Formation and retention of cotinine during placental transfer of nicotine in human placental cotyledon. Pharmacology, 1998, Volume: 57, Issue:2 Topics: Adult; Antipyrine; Cotinine; Female; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Nicotine; Perfusion; Placenta; Pregnancy	1998
Effects of nicotine-specific antibodies, Nic311 and Nic-IgG, on the transfer of nicotine across the human placenta. Biochemical pharmacology, 2005, Nov-25, Volume: 70, Issue:11 Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antipyrine; Drug Evaluation, Preclinical; Female; Humans; Immunoglobulin G; Maternal-Fetal Exchange; Mice; Nicotine; Perfusion; Placenta; Pregnancy; Protein Binding; Rabbits	2005
Acute effects of ethanol on the transfer of nicotine and two dietary carcinogens in human placental perfusion. Toxicology letters, 2011, Sep-10, Volume: 205, Issue:3 Topics: Adenocarcinoma; Antipyrine; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Carbon Radioisotopes; Carcinogens; Cell Line, Tumor; Diffusion; Dimethylnitrosamine; Ethanol; Female; Food Contamination; Humans; Imidazoles; In Vitro Techniques; Indicators and Reagents; Kinetics; Neoplasm Proteins; Nicotine; Perfusion; Placenta; Pregnancy	2011