antipyrine and morphine

antipyrine has been researched along with morphine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199018 (58.06)18.7374
1990's1 (3.23)18.2507
2000's8 (25.81)29.6817
2010's4 (12.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Jolivette, LJ; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Booker, PD; Chapman, DH1
Ishikawa, M; Sasaki, K; Sugawara, S; Takayanagi, Y1
Cozzolino, S; La Rotonda, MI; Lembo, S; Lisciani, R; Silipo, C; Vittoria, A1
Hachisu, M; Hiranuma, T; Murata, S; Shibazaki, Y; Takahashi, H1
Bartsch, H; Day, NE; Ghadirian, P; Gorodetzky, C; Mahon, GA; Roberfroid, MB; Stein, GF1
Passananti, GT; Vessell, ES1
Guivernau, M; Muñoz, C; Paeile, C1
Oldendorf, WH1
Arnold, W1
Chinard, FP; Effros, RM1
Inukai, T; Nakama, M; Takagi, H1
Kreppel, E1
Breckenridge, A; Brooks, RV; Davies, DS; Orme, ML; Thorgeirsson, S1
Ankermann, H; Klinger, W; Kusch, T; Neugebauer, A; Splinter, FK1
Aanderud, L; Bakke, OM1
Bertolini, A; Pini, LA; Sandrini, M; Sternieri, E; Vitale, G1
AXELROD, J1
CHANG, TM; WU, YP1
JACOB, J; SZERB, J1

Reviews

1 review(s) available for antipyrine and morphine

ArticleYear
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays

1971

Trials

1 trial(s) available for antipyrine and morphine

ArticleYear
Premedication in children undergoing day-care surgery.
    British journal of anaesthesia, 1979, Volume: 51, Issue:11

    Topics: Acetaminophen; Administration, Oral; Antipyrine; Atropine; Child; Child, Preschool; Chloral Hydrate; Day Care, Medical; Humans; Infant; Injections, Intramuscular; Morphine; Postoperative Complications; Premedication; Surgical Procedures, Operative

1979

Other Studies

29 other study(ies) available for antipyrine and morphine

ArticleYear
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
The effect of endotoxin on nociception in mice.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 65, Issue:1

    Topics: Animals; Antipyrine; Benzoquinones; Dose-Response Relationship, Drug; Endotoxins; Male; Mice; Mice, Inbred Strains; Morphine; Nociceptors; Pain; Quinones; Time Factors

1989
Structure-analgesic activity relationships in a set of 2-aminobenzamide derivatives.
    Il Farmaco; edizione scientifica, 1986, Volume: 41, Issue:2

    Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Autonomic Nervous System; Behavior, Animal; Chemical Phenomena; Chemistry; Codeine; Female; Lethal Dose 50; Male; Mice; Morphine; ortho-Aminobenzoates; Prostaglandins; Rats; Rats, Inbred Strains; Species Specificity; Structure-Activity Relationship

1986
Relationship between enkephalinase inhibition of thiorphan in vivo and its analgesic activity.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9

    Topics: Amino Acids, Sulfur; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Brain; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Mice; Morphine; Neprilysin; Nerve Tissue Proteins; Nociceptors; Protease Inhibitors; Rats; Rats, Inbred Strains; Reaction Time; Thiorphan; Tiopronin

1985
Oesophageal cancer studies in the Caspian littoral of Iran: some residual results, including opium use as a risk factor.
    International journal of cancer, 1985, May-15, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Antipyrine; Child; Esophageal Neoplasms; Female; Half-Life; Humans; Iran; Male; Middle Aged; Morphine; Opium; Risk; Sex Factors; Substance-Related Disorders

1985
Influence of anti-inflammatory drugs on the electroencephalographic effect of morphine in rabbits.
    Pharmacology, 1974, Volume: 11, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antipyrine; Electroencephalography; Indomethacin; Male; Mefenamic Acid; Mesylates; Morphine; Rabbits; Salicylates; Stimulation, Chemical

1974
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
[GC/MS demonstration of opium alkaloids in opium preparations (in connection with an on-line linked small computer)].
    Beitrage zur gerichtlichen Medizin, 1974, Volume: 32

    Topics: Antipyrine; Chromatography, Gas; Codeine; Computers; Morphine; Noscapine; Opium; Papaverine

1974
The in vivo pH of the extravascular space of the lung.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:11

    Topics: Amines; Aniline Compounds; Animals; Antipyrine; Atropine; Carbon Dioxide; Dogs; Dye Dilution Technique; Guanidines; Histamine; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Ketones; Lung; Mathematics; Mescaline; Morphine; Nicotine; Oxyphenbutazone; Partial Pressure; Quinine; Radioisotope Dilution Technique; Tritium

1969
A modification of Haffner's method for testing analgesics.
    Japanese journal of pharmacology, 1966, Volume: 16, Issue:3

    Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Biological Assay; Codeine; Female; Male; Mice; Morphine; Phenacetin

1966
[Principles and risks of drug treatment of pain].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Aminopyrine; Analgesics; Antidepressive Agents; Antipyrine; Aspirin; Codeine; Dibenzazepines; Humans; Imipramine; Levallorphan; Levorphanol; Methadone; Morphine; Pain; Phenacetin; Phenylbutazone; Pyrazoles; Salicylamides; Salicylates; Sulfonic Acids

1969
Drug interactions with warfarin: studies with dichloralphenazone, chloral hydrate and phenazone (antipyrine).
    Clinical science, 1971, Volume: 40, Issue:4

    Topics: Animals; Antipyrine; Carbon Isotopes; Chloral Hydrate; Enzyme Induction; Glucocorticoids; Humans; Liver; Microsomes, Liver; Morphine; Pentobarbital; Rats; Warfarin; Zoxazolamine

1971
[Studies of the mechanism of enzyme induction. XIV. Effect of age on the activity and inducibility of phenazone hydroxylases, aminophenazone-N-demethylase, codeine-O-demethylase and nitroreductase of the rat liver].
    Acta biologica et medica Germanica, 1968, Volume: 21, Issue:3

    Topics: Age Factors; Aging; Aminopyrine; Animals; Animals, Newborn; Antipyrine; Barbiturates; Codeine; Enzyme Induction; Injections, Intraperitoneal; Liver; Male; Mixed Function Oxygenases; Morphine; Nitrobenzenes; Oxidoreductases; Proteins; Rats; Spectrophotometry

1968
Pharmacokinetics of antipyrine, paracetamol, and morphine in rat at 71 ATA.
    Undersea biomedical research, 1983, Volume: 10, Issue:3

    Topics: Acetaminophen; Animals; Antipyrine; Atmosphere Exposure Chambers; Atmospheric Pressure; Carbon Radioisotopes; Kinetics; Male; Morphine; Rats; Rats, Inbred Strains; Time Factors; Tritium

1983
Effects of chronic treatment with phenazone on the hot-plate test and [3H]serotonin binding sites in pons and cortex membranes of the rat.
    Pharmacology, 1993, Volume: 47, Issue:2

    Topics: Animals; Antipyrine; Binding Sites; Cerebral Cortex; Male; Morphine; Pain Threshold; Pons; Rats; Rats, Wistar; Receptors, Serotonin

1993
PHARMACODYNAMICS OF HUMAN DISEASE. 1. BIOCHEMICAL FACTORS IN THE ACTION OF ANALGESIC AND NARCOTIC DRUGS.
    Postgraduate medicine, 1963, Volume: 34

    Topics: Acetanilides; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Drug Tolerance; Enzymes; Glucuronates; Humans; Metabolism; Morphine; NAD; NADP; Narcotics; Phenacetin; Uracil Nucleotides

1963
[SOME PHARMACOLOGICAL PROPERTIES OF ACEPROMAZINE: ITS POTENTIATING ACTION AND ITS EFFECT ON THE RELEASE OF THE TRANSMITTER FROM THE POST-GANGLIONIC SYMPATHETIC NERVE FIBRES].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1964, Volume: 11

    Topics: Acepromazine; Analgesia; Animals; Antipyrine; Blood Pressure; Cats; Chloral Hydrate; Chlorpromazine; Cornea; Epinephrine; Ileum; Morphine; Muscle, Smooth; Nerve Endings; Nerve Fibers; Nictitating Membrane; Norepinephrine; Peripheral Nerves; Pharmacology; Procaine; Research; Sympathetic Nervous System; Vasomotor System

1964
[Effects of adrenalectomy on the thermoanalgesic phenomena provoked by cortisone, ACTH, formalin, epinephrine, morphine & pyramidone].
    Experientia, 1951, Volume: 7, Issue:12

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Antipyrine; Cortisone; Epinephrine; Formaldehyde; Humans; Morphine

1951