antipyrine has been researched along with metronidazole in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (35.48) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 6 (19.35) | 29.6817 |
| 2010's | 3 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Loft, S; Otte, J; Poulsen, HE; Sørensen, H | 1 |
| Borg, BE; Loft, S; Nielsen, AJ; Poulsen, HE | 1 |
| Loft, S; Poulsen, HE | 3 |
| Loft, S | 1 |
| Weiss, M | 1 |
| Dorfeldt, A; Hamberg, O; Loft, S; Ovesen, L; Sonne, J | 1 |
| Døssing, M; Loft, S; Schroeder, E; Sonne, J | 1 |
| Døssing, M; Loft, S; Poulsen, HE; Sonne, J | 1 |
| Descotes, J; Evreux, JC; Simonet, R | 1 |
| Døssing, M; Jørgensen, BG; Loft, S; Petersen, KT; Poulsen, HE; Sonne, J | 1 |
| Back, DJ; Breckenridge, AM; Purba, HS | 1 |
| Gugler, R; Jensen, JC | 1 |
| Hospador, MA; Manthei, RW | 1 |
| Gajewska, M | 1 |
| Baird-Lambert, J; Buchanan, N; Cvejic, M; Farrell, G; Zaluzny, L | 1 |
| de Vries, J; Staiger, C; Wang, NS; Weber, E | 1 |
| Brøsen, K; Dalhoff, K; Flachs, H; Loft, S; Poulsen, HE; Ranek, L; Wantzin, P | 1 |
| Jeding, IB; Loft, S; Poulsen, HE | 1 |
| Edwards, G; Glazier, AP; Ismail, S; Kokwaro, GO; Ward, SA | 1 |
2 review(s) available for antipyrine and metronidazole
| Article | Year |
|---|---|
Prediction of xenobiotic metabolism by non-invasive methods.
Topics: Acetylation; Aminopyrine; Antipyrine; Biotransformation; Carbon Dioxide; Cytochrome P-450 Enzyme System; Humans; Metronidazole; Saliva; Xenobiotics | 1990 |
Metronidazole and antipyrine as probes for the study of foreign compound metabolism.
Topics: Animals; Antipyrine; Humans; Metronidazole; Xenobiotics | 1990 |
2 trial(s) available for antipyrine and metronidazole
| Article | Year |
|---|---|
The effect of dietary energy and protein deficiency on drug metabolism.
Topics: Adult; Antipyrine; Biotransformation; Body Weight; Diet; Energy Metabolism; Glucuronates; Humans; Male; Metronidazole; Oxazepam; Oxidation-Reduction; Pharmaceutical Preparations; Protein Deficiency; Saliva | 1990 |
[Effect of metronidazole on phenazone metabolism].
Topics: Adult; Antipyrine; Cimetidine; Drug Interactions; Female; Humans; Hydroxylation; Kinetics; Male; Metronidazole; Time Factors | 1984 |
27 other study(ies) available for antipyrine and metronidazole
| Article | Year |
|---|---|
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics | 1996 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Influence of intact and myrosinase-treated indolyl glucosinolates on the metabolism in vivo of metronidazole and antipyrine in the rat.
Topics: Animals; Antipyrine; Body Weight; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucosinolates; Glycoside Hydrolases; Hydrolysis; Indoles; Isoenzymes; Liver; Male; Metronidazole; Organ Size; Rats; Rats, Wistar | 1992 |
Metronidazole and antipyrine metabolism in the rat: clearance determination from one saliva sample.
Topics: Animals; Antipyrine; Drug Interactions; Male; Metabolic Clearance Rate; Metronidazole; Rats; Rats, Inbred Strains; Saliva | 1991 |
Metabolism of metronidazole and antipyrine in hepatocytes isolated from mouse and rat.
Topics: Acetates; Acetic Acid; Animals; Antipyrine; Glucuronates; Hydroxylation; Kinetics; Liver; Male; Metronidazole; Mice; Rats; Rats, Inbred Strains | 1990 |
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Ketanserin; Lidocaine; Liver Diseases; Metronidazole; Nomifensine; Triamterene | 1990 |
Metabolism of metronidazole and antipyrine in isolated rat hepatocytes. Influence of sex and enzyme induction and inhibition.
Topics: Acetates; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Glucuronates; Hydroxides; Isoenzymes; Kinetics; Liver; Male; Methylcholanthrene; Metronidazole; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors; Sulfates | 1989 |
Antipyrine and metronidazole metabolism during occupational exposure to gasoline.
Topics: Adult; Antipyrine; Environmental Exposure; Gasoline; Humans; Metronidazole; Middle Aged; Petroleum; Smoking | 1988 |
Metronidazole clearance: a one-sample method and influencing factors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Antipyrine; Chromatography, High Pressure Liquid; Coffee; Drug Interactions; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Metronidazole; Middle Aged; Saliva; Smoking; Tea | 1988 |
[Spiramycin-metronidazole combination: absence of metabolic interactions].
Topics: Adult; Antipyrine; Drug Combinations; Drug Interactions; Female; Humans; Leucomycins; Male; Metronidazole; Middle Aged | 1987 |
Inhibition and induction of metronidazole and antipyrine metabolism.
Topics: Adult; Antipyrine; Cimetidine; Drug Interactions; Female; Humans; Hydroxylation; Kinetics; Male; Metronidazole; Phenobarbital | 1987 |
Inhibition of estrogen 2-hydroxylase.
Topics: Animals; Antipyrine; Chloroquine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Diethylstilbestrol; Estradiol; Ethinyl Estradiol; Imidazoles; Kinetics; Male; Metronidazole; Microsomes, Liver; Primaquine; Rats; Rats, Inbred Strains; Steroid Hydroxylases | 1986 |
Interaction between metronidazole and drugs eliminated by oxidative metabolism.
Topics: Administration, Oral; Adult; Antipyrine; Chromatography, Gas; Diazepam; Drug Interactions; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Male; Metronidazole; Phenytoin | 1985 |
Influence of age and diet on the induction of hexobarbital-metabolizing enzymes in the mouse.
Topics: Age Factors; Animals; Animals, Newborn; Antipyrine; Benzopyrenes; Biotransformation; Caseins; Diet; Enzyme Induction; Hexobarbital; Histamine H1 Antagonists; Liver; Male; Metronidazole; Mice; Microsomes; Oils; Phenobarbital; Piperazines; Sleep; Starvation; Zea mays | 1968 |
Complexometric determination of various diazole derivatives with cupric picrate.
Topics: Aminopyrine; Antipyrine; Azoles; Copper; Histamine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Methods; Metronidazole; Phenylbutazone; Phenytoin; Picrates; Structure-Activity Relationship; Tolazoline | 1972 |
Impaired elimination of metronidazole in decompensated chronic liver disease.
Topics: Adult; Aged; Antipyrine; Female; Half-Life; Hepatitis, Chronic; Humans; Liver Diseases, Alcoholic; Male; Metronidazole; Middle Aged | 1983 |
Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis.
Topics: Adult; Aged; Antipyrine; Chemical and Drug Induced Liver Injury; Complement C3; Female; Halothane; HLA Antigens; Humans; Male; Mephenytoin; Metronidazole; Middle Aged; Phenotype; Phenytoin; Polymorphism, Genetic; Sparteine | 1993 |
Non-induction of extrahepatic antipyrine and metronidazole metabolism evaluated from partially hepatectomized rats.
Topics: Administration, Oral; Animals; Antipyrine; Benzoflavones; beta-Naphthoflavone; Hepatectomy; Injections, Intraperitoneal; Intestinal Mucosa; Intestines; Male; Metronidazole; Organ Size; Rats; Rats, Wistar; Saliva | 1993 |
Effect of malaria infection and endotoxin-induced fever on the metabolism of antipyrine and metronidazole in the rat.
Topics: Animals; Antipyrine; Body Temperature; Disease Models, Animal; Endotoxins; Fever; Lipopolysaccharides; Malaria; Male; Metabolic Clearance Rate; Metronidazole; Pharmaceutical Preparations; Plasmodium berghei; Rats; Rats, Wistar; Saliva | 1993 |