Compounds > antipyrine

antipyrine and melphalan

antipyrine has been researched along with melphalan in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Gutsche, W; Jungstand, W; Werner, W; Wohlrabe, K1
Noker, PE; Simpson-Herren, L1
Collins, FG; Skibba, JL1

Other Studies

7 other study(ies) available for antipyrine and melphalan

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[The synthesis and carcinostatic effect of 4-[bis-(2-chloroethyl)-amino]-2, 3-dimethyl-1-phenyl-5-pyrazolone ("imet 3995")].
    Die Pharmazie, 1975, Volume: 30, Issue:7

    Topics: Ampyrone; Animals; Antineoplastic Agents; Antipyrine; Carcinoma 256, Walker; Drug Evaluation, Preclinical; Female; Lethal Dose 50; Leukemia, Experimental; Male; Melphalan; Mice; Nitrogen Mustard Compounds; Rats; Sarcoma 180

1975
Diversity of penetration of anti-cancer agents into solid tumours.
    Cell proliferation, 1991, Volume: 24, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Antineoplastic Agents; Antipyrine; Biological Transport; Breast Neoplasms; Carbon Radioisotopes; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Melphalan; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Transplantation, Heterologous

1991
Altered hepatic functions and microsomal activity in perfused rat liver by hyperthermia combined with alkylating agents.
    Cancer biochemistry biophysics, 1983, Volume: 6, Issue:4

    Topics: Alkylating Agents; Animals; Antipyrine; Biotransformation; Cyclophosphamide; Gluconeogenesis; Liver; Male; Mechlorethamine; Melphalan; Microsomes, Liver; Oxygen Consumption; Rats; Urea

1983