antipyrine and hydroxyl radical

antipyrine has been researched along with hydroxyl radical in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (14.29)18.2507
2000's13 (61.90)29.6817
2010's4 (19.05)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Egawa, M; Nishi, H; Watanabe, T; Yuki, S1
Kogure, K; Mitsuka, M; Saito, KI; Watanabe, T; Yamamoto, T; Yuki, S1
Mizuno, A; Nakashima, M; Umemura, K1
Ikeda, Y; Satoh, K; Shioda, S; Tobe, T; Yoshikawa, T1
Hashiba, Y; Imai, H; Saito, N; Sasaki, T; Shimizu, T; Tosaka, M1
Abe, S; Hasegawa, T; Houchi, H; Kirima, K; Okamoto, M; Tamaki, T; Tsuchiya, K; Yoshizumi, M1
Harada, N; Maehara, Y; Ninomiya, M; Shimada, M; Soejima, Y; Suehiro, T1
Nomoto, N1
Akamatsu, H; Mikawa, K; Nishina, K; Niwa, Y; Obara, H1
Jesmin, S; Kakehata, H; Matsumoto, M; Otani, H; Sakuma, I; Togashi, H; Yamaguchi, T; Yoshioka, M1
Hayakawa, Y; Masaoka, N; Nagaishi, M; Nakajima, Y; Sakata, H; Watanabe, M; Yamamoto, T1
H S, AK; Patel, RJ; Saini, AK; Sharma, SS1
Kimata, A; Miyata, N; Nakagawa, H; Ohyama, R; Suzuki, T1
Deshmukh, AB; Patel, NJ; Patel, RJ1
Chen, FJ; Liu, XH; Liu, Y; Xi, PX; Xu, ZH; Zeng, ZZ; Zhang, XW1
Ding, SJ; Han, N; Wu, T; Zhu, YL1
Fu, H; Hata, K; Katsumura, Y; Lin, M; Muroya, Y; Nakagawa, H; Yamashita, S1
Galano, A; Pérez-González, A1
Daoud, GA; Fukuda, S; Goto, T; Hashimoto, T; Hussein, MH; Ito, T; Kakita, H; Kato, I; Kato, S; Mizuno, H; Suzuki, S; Togari, H; Yamaguchi, S1
Fu, H; Hata, K; Katsumura, Y; Lin, M; Muroya, Y; Shikazono, N; Urushibara, A; Yamashita, S; Yokoya, A1
Chu, W; Gan, L; Gong, H; Lai, WY; Lin, J; Wang, Q; Xu, L1

Other Studies

21 other study(ies) available for antipyrine and hydroxyl radical

ArticleYear
Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Alloxan; Animals; Antioxidants; Antipyrine; Brain; Brain Ischemia; Edaravone; Embolization, Therapeutic; Energy Metabolism; Free Radical Scavengers; Hydroxyl Radical; Islets of Langerhans; Lipid Peroxidation; Male; Mitochondria; Rats; Rats, Wistar; Regional Blood Flow; Superoxides

1994
Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia.
    Brain research, 1997, Jul-11, Volume: 762, Issue:1-2

    Topics: Animals; Antipyrine; Brain Ischemia; Cell Death; Edaravone; Free Radical Scavengers; Hippocampus; Hydroxybenzoates; Hydroxyl Radical; Iron Chelating Agents; Male; Microdialysis; Neurons; Rats; Rats, Wistar; Reperfusion Injury

1997
Inhibitory effect of MCI-186, a free radical scavenger, on cerebral ischemia following rat middle cerebral artery occlusion.
    General pharmacology, 1998, Volume: 30, Issue:4

    Topics: Animals; Antipyrine; Brain; Brain Ischemia; Cerebral Arteries; Constriction; Edaravone; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Male; Rats; Rats, Wistar; Visual Cortex

1998
Edarabone scavenges nitric oxide.
    Redox report : communications in free radical research, 2002, Volume: 7, Issue:4

    Topics: Antioxidants; Antipyrine; Dose-Response Relationship, Drug; Edaravone; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Nitric Oxide

2002
Contractile responses to reactive oxygen species in the canine basilar artery in vitro: selective inhibitory effect of MCI-186, a new hydroxyl radical scavenger.
    Acta neurochirurgica, 2002, Volume: 144, Issue:12

    Topics: Animals; Antipyrine; Basilar Artery; Disease Models, Animal; Dogs; Edaravone; Female; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Male; Oxidants; Reactive Oxygen Species; Superoxides; Vasospasm, Intracranial

2002
The reaction rate of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with hydroxyl radical.
    Chemical & pharmaceutical bulletin, 2004, Volume: 52, Issue:2

    Topics: Antipyrine; Cyclic N-Oxides; Edaravone; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Oxidation-Reduction; Spin Trapping

2004
The hydroxyl radical scavenger MCI-186 protects the liver from experimental cold ischaemia-reperfusion injury.
    The British journal of surgery, 2004, Volume: 91, Issue:2

    Topics: Animals; Antipyrine; Cold Temperature; Edaravone; Free Radical Scavengers; Hydroxyl Radical; Interleukin-10; Liver; Liver Diseases; Male; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Weight Gain

2004
Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats.
    Journal of the neurological sciences, 2004, Apr-15, Volume: 219, Issue:1-2

    Topics: Animals; Antipyrine; Brain; Edaravone; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Male; Movement Disorders; Nitriles; Rats; Rats, Wistar

2004
Effects of edaravone on human neutrophil function.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:3

    Topics: Antipyrine; Calcium; Chemotaxis; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Neutrophils; Phagocytosis; Reactive Oxygen Species; Reference Values; Xanthine; Xanthine Oxidase

2005
Temporal effects of edaravone, a free radical scavenger, on transient ischemia-induced neuronal dysfunction in the rat hippocampus.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: Animals; Antipyrine; Blotting, Western; Brain Ischemia; Edaravone; Fibroblast Growth Factor 2; Fluorescent Antibody Technique; Free Radical Scavengers; Hippocampus; Hydroxyl Radical; Long-Term Potentiation; Male; Microscopy, Confocal; Nitric Oxide Synthase; Perforant Pathway; Rats; Rats, Wistar; Time Factors; Vascular Endothelial Growth Factor A

2005
The production of hydroxyl radicals in the fetal lamb brain resulting from occlusion of the umbilical circulation and the transplacental effect of MCI-186 to inhibit hydroxyl radical production.
    Pediatric research, 2006, Volume: 59, Issue:2

    Topics: Animals; Antipyrine; Brain; Catechols; Edaravone; Female; Free Radical Scavengers; Hydroxybenzoates; Hydroxyl Radical; Maternal-Fetal Exchange; Pregnancy; Regional Blood Flow; Sheep; Umbilical Cord

2006
Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats.
    Pharmacological research, 2006, Volume: 54, Issue:1

    Topics: Angiotensin II; Animals; Antipyrine; Aorta, Thoracic; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Edaravone; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; tert-Butylhydroperoxide; Vasoconstriction

2006
Hydroxyl radical scavenging by edaravone derivatives: Efficient scavenging by 3-methyl-1-(pyridin-2-yl)-5-pyrazolone with an intramolecular base.
    Bioorganic & medicinal chemistry letters, 2006, Dec-01, Volume: 16, Issue:23

    Topics: Antipyrine; Edaravone; Free Radical Scavengers; Hydroxyl Radical; Molecular Structure; Oxidation-Reduction; Pyrazolones; Pyridines

2006
Hydroxyl radical mediates the augmented angiotensin II responses in thoracic aorta of spontaneously hypertensive rats.
    Pharmacology, 2007, Volume: 79, Issue:2

    Topics: Angiotensin II; Animals; Antipyrine; Aorta, Thoracic; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Hydrogen Peroxide; Hydroxyl Radical; Muscle, Smooth, Vascular; Peroxides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; tert-Butylhydroperoxide; Vasoconstriction

2007
Synthesis, characterization, antioxidant activity and DNA-binding studies of three rare earth (III) complexes with 1-(4-aminoantipyrine)-3-tosylurea ligand.
    Journal of fluorescence, 2009, Volume: 19, Issue:1

    Topics: Antioxidants; Antipyrine; Binding Sites; Circular Dichroism; DNA; Dose-Response Relationship, Drug; Electrodes; Hydroxyl Radical; Ligands; Metals, Rare Earth; Molecular Structure; Organometallic Compounds; Spectrometry, Fluorescence; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Urea; Viscosity

2009
Correlation of free radical level and apoptosis after intracerebral hemorrhage in rats.
    Neuroscience bulletin, 2008, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Antipyrine; Apoptosis; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Hydroxyl Radical; In Situ Nick-End Labeling; Linear Models; Male; Malondialdehyde; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors

2008
Pulse radiolysis study on free radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one). 2: A comparative study on edaravone derivatives.
    Journal of radiation research, 2011, Volume: 52, Issue:1

    Topics: Antipyrine; Computer Simulation; Edaravone; Free Radical Scavengers; Hydroxyl Radical; Models, Chemical; Nitrogen; Pulse Radiolysis

2011
OH radical scavenging activity of Edaravone: mechanism and kinetics.
    The journal of physical chemistry. B, 2011, Feb-10, Volume: 115, Issue:5

    Topics: Antipyrine; Diffusion; Edaravone; Electron Transport; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Thermodynamics

2011
Edaravone, a hydroxyl radical scavenger, ameliorates the severity of pulmonary hypertension in a porcine model of neonatal sepsis.
    The Tohoku journal of experimental medicine, 2011, Volume: 223, Issue:4

    Topics: Animals; Antipyrine; Blood Pressure; Edaravone; Free Radical Scavengers; Humans; Hydroxyl Radical; Hypertension, Pulmonary; Infant, Newborn; Infant, Newborn, Diseases; Sepsis; Swine; Tumor Necrosis Factor-alpha

2011
Chemical repair activity of free radical scavenger edaravone: reduction reactions with dGMP hydroxyl radical adducts and suppression of base lesions and AP sites on irradiated plasmid DNA.
    Journal of radiation research, 2015, Volume: 56, Issue:1

    Topics: Antipyrine; Base Sequence; DNA Adducts; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Edaravone; Free Radical Scavengers; Hydroxyl Radical; Molecular Sequence Data; Oxidation-Reduction; Plasmids; Pulse Radiolysis; Radiation Dosage

2015
A comparative study on phenazone degradation by sulfate radicals based processes.
    Environmental research, 2020, Volume: 191

    Topics: Antipyrine; Environmental Pollutants; Hydroxyl Radical; Oxidation-Reduction; Sulfates; Water Pollutants, Chemical

2020