antipyrine has been researched along with fluorouracil in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Capel, ID; Dorrell, HM; Jenner, M; Williams, DC | 1 |
| Cieślińska, A; Orzechowska-Juzwenko, K; Roszkowska, E; Wiela, A | 1 |
| Aarbakke, J; Høyem-Johansen, T; Slørdal, L | 1 |
| Huttunen, R; Kairaluoma, MI; Laitinen, S; Larmi, TK; Mokka, RE; Sotaniemi, EA | 1 |
| Allen-Mersh, TG; Burke, D; Carnochan, P; Glover, C | 1 |
13 other study(ies) available for antipyrine and fluorouracil
| Article | Year |
|---|---|
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics | 1996 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Hepatic function assessed (in rats) during chemotherapy with some anti-cancer drugs.
Topics: Alkaline Phosphatase; alpha-Fetoproteins; Animals; Antipyrine; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cyclophosphamide; Dactinomycin; Fluorouracil; gamma-Glutamyltransferase; Glutamate Dehydrogenase; Liver; Male; Methotrexate; Ornithine Carbamoyltransferase; Rats; Vincristine | 1979 |
Metabolic efficiency of the liver in patients with breast cancer as determined by pharmacokinetics of phenazone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antipyrine; Biotransformation; Breast Neoplasms; Carcinoma; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Liver; Metabolic Clearance Rate; Methotrexate; Middle Aged | 1987 |
Microsomal metabolism of antipyrine in rats treated with antineoplastic drugs.
Topics: Animals; Antineoplastic Agents; Antipyrine; Body Weight; Cyclophosphamide; Fluorouracil; Kinetics; Male; Methotrexate; Microsomes, Liver; Organ Size; Rats; Rats, Inbred Strains | 1983 |
Effect of surgery on liver function in patients with liver cancer.
Topics: Adult; Aged; Antipyrine; Female; Fluorouracil; Humans; Ligation; Liver; Liver Function Tests; Liver Neoplasms; Male; Middle Aged | 1982 |
Correlation between tumour blood flow and fluorouracil distribution in a hypovascular liver metastasis model.
Topics: Animals; Antimetabolites, Antineoplastic; Antipyrine; Calibration; Colorectal Neoplasms; Fluorouracil; Liver Neoplasms; Male; Rats; Regional Blood Flow | 2000 |