antipyrine has been researched along with digoxin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bender, AD; Richey, DP | 1 |
| Bass, O; Baur, HR; Masson, JP; Ohnhaus, EE | 1 |
| Petrin, A | 1 |
| Cohn, VH; Sieber, SM; Wynn, WT | 1 |
| Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K | 1 |
| Jung, S; Reinsberg, J; Schlebusch, H; Schmolling, J | 2 |
| Gandia, P; Houin, G; Lacombe, O; Woodley, J | 1 |
| Brenner, SS; Drescher, S; Eichelbaum, M; Fromm, MF; Glaeser, H; Heinkele, G; Hofmann, U; Igel, S; Mürdter, T; Omari, T; Schäfer, C; Somogyi, AA; Tegude, H | 1 |
| Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
2 review(s) available for antipyrine and digoxin
| Article | Year |
|---|---|
Pharmacokinetic consequences of aging.
Topics: Adult; Aged; Aging; Aminopyrine; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Blood Proteins; Digoxin; Disease; Female; Humans; Intestinal Absorption; Kidney; Kinetics; Male; Middle Aged; Pharmaceutical Preparations; Phenytoin; Protein Binding; Rats | 1977 |
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
2 trial(s) available for antipyrine and digoxin
| Article | Year |
|---|---|
Lack of pantoprazole drug interactions in man.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin | 1994 |
Increased absorption of digoxin from the human jejunum due to inhibition of intestinal transporter-mediated efflux.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport, Active; Digoxin; Enterocytes; Enzyme Inhibitors; Epithelial Cells; Humans; Intestinal Absorption; Jejunum; Male; Protein Transport; Quinidine; Xenobiotics | 2007 |
17 other study(ies) available for antipyrine and digoxin
| Article | Year |
|---|---|
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
[The pharmacokinetics of digoxin during chronic spironolacton treatment (author's transl)].
Topics: Adult; Aged; Antipyrine; Digoxin; Feces; Female; Half-Life; Heart Failure; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Spironolactone | 1978 |
[Pharmacokinetics of drugs in the elderly].
Topics: Adult; Age Factors; Aged; Aging; Antipyrine; Digoxin; Dihydrostreptomycin Sulfate; Glomerular Filtration Rate; Humans; Kinetics; Middle Aged; Penicillin G; Penicillin V; Penicillins; Pharmaceutical Preparations; Phenylbutazone; Tetracycline | 1974 |
The entry of foreign compounds into the thoracic duct lymph of the rat.
Topics: Acids; Alcohols; Amines; Aniline Compounds; Animals; Anthracenes; Antipyrine; Benzoates; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Chromatography, Thin Layer; Chylomicrons; DDT; Digoxin; Estradiol; Isoniazid; Lymph; Male; Phenanthrenes; Salicylates; Testosterone; Thoracic Duct; Time Factors; Tritium | 1974 |
Digoxin transfer across the isolated placenta is influenced by maternal and fetal albumin concentrations.
Topics: Anti-Arrhythmia Agents; Antipyrine; Culture Media; Digoxin; Female; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Medigoxin; Metabolic Clearance Rate; Perfusion; Placenta; Pregnancy; Serum Albumin, Bovine; Statistics, Nonparametric | 1996 |
Diffusion characteristics of placental preparations affect the digoxin passage across the isolated placental lobule.
Topics: Anti-Arrhythmia Agents; Antipyrine; Diffusion; Digoxin; Female; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Perfusion; Placenta; Pregnancy | 1997 |
The perfused everted intestinal segment of rat. 1st communication: absorption kinetics of markers of different permeation mechanisms.
Topics: Algorithms; Animals; Antipyrine; Cardiotonic Agents; Digoxin; In Vitro Techniques; Intestinal Absorption; Intestines; Mannitol; Models, Biological; Perfusion; Permeability; Proteins; Rats | 2004 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |