antipyrine and diazepam

antipyrine has been researched along with diazepam in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (40.00)	18.7374
1990's	9 (16.36)	18.2507
2000's	16 (29.09)	29.6817
2010's	8 (14.55)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ghuloum, AM; Jain, AN; Sage, CR	1
Coassolo, P; Lavé, T; Schneider, G	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Ertl, P; Rohde, B; Selzer, P	1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Bas, D; Bruneau, P; Chipot, C; Dorison-Duval, D; Moreau, S	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Caron, G; Ermondi, G	1
Carrupt, PA; Martel, S; Ottaviani, G	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Colombo, JP; Heizmann, P; Ohnhaus, EE; Park, BK	1
Paumgartner, G	1
Albanus, L; Jönsson, M; Sparf, B	1
Dengler, HJ; Eichelbaum, M	1
Benes, I; Blum, AL; Herz, R; Koelz, HR; Sonnenberg, A	1
Azarnoff, DL; Gugler, R	1
Harvey, HA; Hepner, GW; Lipton, A; Schenker, S; Vesell, ES; Wilkinson, GR	1
Eichhorst, BC; Seeds, AE; Stolee, A	1
Anan'ev, EA; Grek, OR; Kolpakov, MA; Sharapov, VI	1
Humphries, TJ	1
Karim, A; Nicholson, PA; Smith, M	1
Bianchi, M; Caccia, S; Conti, I; Duan, L; Ghezzi, P; Tridico, R	1
Brockmeyer, N; Dylewicz, P; Habicht, H; Ohnhaus, EE	1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y	1
Gugler, R; Jensen, JC	1
Breckenridge, A; Moss, DW; Neale, G; Orme, M; Whitfield, JB	1
Mascherpa, P	1
Johnstone, M	1
Trzaski, M	1
Abernethy, DR; Eshelman, FN; Greenblatt, DJ; Shader, RI	1
Hignite, CE; Hodges, GR; Kemner, JM; Melethil, S; Snodgrass, WR; Tschanz, C; Worley, SE	1
Keller, F; Waser, PG	1
Klotz, U; Reimann, I	1
Abernethy, DR; Ameer, B; Divoll, M; Greenblatt, DJ; Shader, RI	1
Abernethy, DR; Divoll, M; Greenblatt, DJ; Harmatz, JS; Shader, RI	1
Roberts, MS; Singh, P	1
Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K	1
Grek, OR; Sharapov, VI	1
Koester, A; Roberts, MS; Weiss, M; Wu, ZY	1
Charman, SA; Katneni, K; Porter, CJ	1
Kim, S; Koyanagi, T; Yamaura, Y; Yamazaki, H; Yano, K	1

Reviews

4 review(s) available for antipyrine and diazepam

Article	Year
Drug protein binding and the nephrotic syndrome. Clinical pharmacokinetics, 1976, Volume: 1, Issue:1 Topics: Antipyrine; Blood Proteins; Clofibrate; Diazepam; Half-Life; Humans; Kinetics; Nephrotic Syndrome; Pharmaceutical Preparations; Phenytoin; Prednisone; Protein Binding; Serum Albumin	1976
Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole. Digestive diseases and sciences, 1991, Volume: 36, Issue:12 Topics: Aminopyrine; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Omeprazole; Phenytoin; Propranolol; Theophylline; Warfarin	1991
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats. Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5 Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin	1985
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994

Trials

2 trial(s) available for antipyrine and diazepam

Article	Year
Ranitidine does not impair oxidative or conjugative metabolism: noninteraction with antipyrine, diazepam, and lorazepam. Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:2 Topics: Adult; Antipyrine; Biotransformation; Diazepam; Drug Interactions; Humans; Kinetics; Lorazepam; Male; Middle Aged; Random Allocation; Ranitidine	1984
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994

Article

Year

Ranitidine does not impair oxidative or conjugative metabolism: noninteraction with antipyrine, diazepam, and lorazepam.

Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:2

Topics: Adult; Antipyrine; Biotransformation; Diazepam; Drug Interactions; Humans; Kinetics; Lorazepam; Male; Middle Aged; Random Allocation; Ranitidine

1984

Lack of pantoprazole drug interactions in man.

International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8

Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin

1994

Other Studies

50 other study(ies) available for antipyrine and diazepam

Article	Year
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules. Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10 Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship	1999
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques. Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25 Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats	1999
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20 Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results	2000
Experimental and computational screening models for the prediction of intestinal drug absorption. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil	2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Rational determination of transfer free energies of small drugs across the water-oil interface. Journal of medicinal chemistry, 2002, Jan-03, Volume: 45, Issue:1 Topics: Alkanes; Antipyrine; Caffeine; Computer Simulation; Ganciclovir; Glucose; Pharmaceutical Preparations; Solubility; Water	2002
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities. Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4 Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effect of enzyme induction on diazepam metabolism in man. British journal of clinical pharmacology, 1979, Volume: 8, Issue:6 Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Biotransformation; Diazepam; Endoplasmic Reticulum; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Kinetics; Male	1979
[Drug metabolism in liver diseases]. Zeitschrift fur Gastroenterologie. Verhandlungsband, 1979, Volume: 16 Topics: Antipyrine; Biological Availability; Biotransformation; Diazepam; Humans; Liver; Liver Diseases; Pharmaceutical Preparations; Propranolol; Protein Binding	1979
Multiple oral doses of diazepam, oxazepam and phenobarbital to dogs--behavioural effects and correlation with antipyrine half-life. Acta pharmacologica et toxicologica, 1977, Volume: 40 Suppl 1, Issue:1 Topics: Administration, Oral; Animals; Antipyrine; Behavior, Animal; Diazepam; Dogs; Drug Evaluation, Preclinical; Half-Life; Male; Oxazepam; Phenobarbital; Time Factors	1977
[Polymorphisms and deficient drug metabolism as triggers of toxic reactions (author's transl)]. Arzneimittel-Forschung, 1977, Volume: 27, Issue:96 Topics: Animals; Antipyrine; Cyclacillin; Diazepam; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney Diseases; Pharmacogenetics; Phenylbutazone; Polymorphism, Genetic; Primidone; Rats	1977
[Effect of oral contraceptives on the demethylation of diazepam and dimethyl-N-aminoantipyrine]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Antipyrine; Contraceptives, Oral, Hormonal; Diazepam; Female; Humans	1978
Disposition of aminopyrine, antipyrine, diazepam, and indocyanine green in patients with liver disease or on anticonvulsant drug therapy: diazepam breath test and correlations in drug elimination. The Journal of laboratory and clinical medicine, 1977, Volume: 90, Issue:3 Topics: Adult; Aged; Aminopyrine; Anticonvulsants; Antipyrine; Breath Tests; Diazepam; Half-Life; Humans; Indocyanine Green; Liver; Liver Diseases; Male; Metabolic Clearance Rate; Middle Aged; Time Factors	1977
Permeability of human chorion laeve to diazepam and meperidine. Obstetrics and gynecology, 1976, Volume: 47, Issue:1 Topics: Aminohippuric Acids; Antipyrine; Cell Membrane Permeability; Chorion; Diazepam; Diffusion; Extraembryonic Membranes; Female; Fetal Blood; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Meperidine; Placenta; Pregnancy	1976
[Pharmacokinetics of antipyrine, nifedipine and diazepam in experimental myocardial infarct]. Biulleten' eksperimental'noi biologii i meditsiny, 1992, Volume: 113, Issue:4 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Hydroxylation; Male; Microsomes, Liver; Myocardial Infarction; Nifedipine; Rats; Rats, Wistar; Time Factors	1992
Pharmacokinetics of misoprostol in the elderly, in patients with renal failure and when coadministered with NSAID or antipyrine, propranolol or diazepam. The Journal of rheumatology. Supplement, 1990, Volume: 20 Topics: Adult; Aged; Aging; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Diazepam; Drug Interactions; Humans; Kidney Failure, Chronic; Liver; Misoprostol; Propranolol	1990
Recombinant tumor necrosis factor reduces hepatic drug metabolism in vivo in the rat. Journal of biological response modifiers, 1988, Volume: 7, Issue:4 Topics: Animals; Antipyrine; Diazepam; In Vitro Techniques; Liver; Male; Rats; Recombinant Proteins; Tumor Necrosis Factor-alpha	1988
The effect of antipyrine and rifampin on the metabolism of diazepam. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2 Topics: 17-Hydroxycorticosteroids; Adult; Antipyrine; Diazepam; Endoplasmic Reticulum; Humans; Hydrocortisone; Kinetics; Male; Microsomes, Liver; Rifampin	1987
Interaction between metronidazole and drugs eliminated by oxidative metabolism. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:4 Topics: Administration, Oral; Adult; Antipyrine; Chromatography, Gas; Diazepam; Drug Interactions; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Male; Metronidazole; Phenytoin	1985
Changes in plasma -glutamyl transpeptidase activity associated with alterations in drug metabolism in man. British medical journal, 1973, Feb-10, Volume: 1, Issue:5849 Topics: Acyltransferases; Adult; Aged; Amobarbital; Antipyrine; Chlordiazepoxide; Diazepam; Enzyme Induction; Female; gamma-Glutamyltransferase; Humans; Male; Methaqualone; Middle Aged; Nitrazepam; Secobarbital; Time Factors; Warfarin	1973
[Aspects of iatrogenic pharmacology and toxicology at the fetal level]. Minerva ginecologica, 1969, Sep-30, Volume: 21, Issue:18 Topics: Aminopyrine; Amitriptyline; Animals; Anti-Bacterial Agents; Antipyrine; Diazepam; Dogs; Female; Fetal Diseases; Fetus; Glucuronates; Humans; Iatrogenic Disease; Oxazepam; Pregnancy; Rabbits; Rats; Tranquilizing Agents	1969
The effects of oral sedatives on the vasoconstrictive reaction to fear. British journal of anaesthesia, 1971, Volume: 43, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Barbiturates; Benperidol; Benzazepines; Blood Vessels; Chloral Hydrate; Chlormethiazole; Diazepam; Dilatation; Diphenhydramine; Drug Synergism; Fear; Fingers; Humans; Hypnotics and Sedatives; Methaqualone; Middle Aged; Plethysmography; Postoperative Care; Preoperative Care	1971
[Effect of various drugs in vivo and in vitro on the results of the most frequently performed enzymatic determinations in a clinical laboratory]. Folia medica Cracoviensia, 1980, Volume: 22, Issue:3-4 Topics: Alanine Transaminase; Alkaline Phosphatase; Aminopyrine; Amylases; Antipyrine; Ascorbic Acid; Aspartate Aminotransferases; Chlorpropamide; Clinical Enzyme Tests; Diazepam; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Female; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Pemoline; Phenylbutazone; Poland; Salicylates	1980
Effect of oxygen-carrying resuscitation fluids on the pharmacokinetics of antipyrine, diazepam, penicillin, and sulfamethazine in rats. Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3 Topics: Animals; Antipyrine; Blood Substitutes; Diazepam; Drug Combinations; Fluorocarbons; Hemoglobins; Hydroxyethyl Starch Derivatives; Kinetics; Male; Penicillins; Rats; Rats, Inbred Strains; Sulfamethazine	1984
Brain pharmacokinetics of centrally acting drugs, a quantitative autoradiographic study. Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 267, Issue:2 Topics: Animals; Antipyrine; Autoradiography; Brain; Cerebrovascular Circulation; Chlorpromazine; Diazepam; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains	1984
Delayed clearance of diazepam due to cimetidine. The New England journal of medicine, 1980, May-01, Volume: 302, Issue:18 Topics: Adult; Antipyrine; Cimetidine; Diazepam; Drug Interactions; Drug Synergism; Female; Guanidines; Half-Life; Humans; Kinetics; Male; Nordazepam	1980
Differential effect of cimetidine on drug oxidation (antipyrine and diazepam) vs. conjugation (acetaminophen and lorazepam): prevention of acetaminophen toxicity by cimetidine. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:3 Topics: Acetaminophen; Adult; Animals; Antipyrine; Biotransformation; Cimetidine; Diazepam; Guanidines; Humans; Kinetics; Lethal Dose 50; Lorazepam; Male; Mice; Oxidation-Reduction	1983
Alterations in drug distribution and clearance due to obesity. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3 Topics: Adult; Antipyrine; Diazepam; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Obesity; Pharmaceutical Preparations	1981
Deep tissue penetration of bases and steroids after dermal application in rat. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:12 Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Antipyrine; Diazepam; Fluocinolone Acetonide; Haloperidol; Hydrocortisone; Male; Progesterone; Rats; Rats, Wistar; Skin Absorption; Steroids; Testosterone	1994
[Activity of liver monooxygenase system in rats with low and high resistance to hypoxia]. Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:9 Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochromes b5; Diazepam; Hypoxia; Male; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Rats; Rats, Wistar; Species Specificity	1996
Distribution kinetics of diazepam, lidocaine and antipyrine in the isolated perfused rat hindlimb. Pharmaceutical research, 1997, Volume: 14, Issue:11 Topics: Animals; Antipyrine; Diazepam; Hindlimb; In Vitro Techniques; Lidocaine; Male; Perfusion; Rats; Rats, Wistar; Tissue Distribution	1997
Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach. Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:10 Topics: Animals; Antipyrine; Cinnarizine; Diazepam; Glycerol; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Micelles; Naproxen; Permeability; Polysorbates; Propranolol; Rats; Rats, Sprague-Dawley; Solubility; Water	2006
Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs. Xenobiotica; the fate of foreign compounds in biological systems, 2014, Volume: 44, Issue:10 Topics: Acetaminophen; Age Factors; Aging; Albumins; Animals; Antipyrine; Blood Proteins; Diazepam; Diphenhydramine; Dogs; Gastric Juice; Hydrogen-Ion Concentration; Macaca fascicularis; Male; Models, Animal; Ofloxacin	2014