antipyrine and chlorpropamide

antipyrine has been researched along with chlorpropamide in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19905 (38.46)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bending, MR; Dollery, CT; Kahn, GC; Mucklow, JC1
Daintith, H; O'Malley, K; Stevenson, IH1
Kärkkäinen, S; Lehtovaara, R; Neuvonen, PJ1
Trzaski, M1
Arranto, AJ; Keinänen, K; Kerola, T; Saarni, HU; Sotaniemi, EA; Stengård, JH; Sutinen, S1
Elliott, BD; Johnson, R; Langer, O; Prihoda, T; Schenker, S1

Other Studies

13 other study(ies) available for antipyrine and chlorpropamide

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Drug concentration in saliva.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Antipyrine; Chlorpropamide; Humans; Hydrogen-Ion Concentration; Male; Meperidine; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Protein Binding; Saliva; Tolbutamide

1978
Influence of diabetes mellitus on drug metabolism in man.
    International journal of clinical pharmacology and biopharmacy, 1976, Volume: 13, Issue:1

    Topics: Antipyrine; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Half-Life; Humans; Insulin; Kinetics; Male; Middle Aged; Pharmaceutical Preparations; Tolbutamide

1976
Pharmacokinetics of chlorpropamide in epileptic patients: effects of enzyme induction and urine pH on chlorpropamide elimination.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:3

    Topics: Adult; Anticonvulsants; Antipyrine; Chlorpropamide; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Middle Aged

1987
[Effect of various drugs in vivo and in vitro on the results of the most frequently performed enzymatic determinations in a clinical laboratory].
    Folia medica Cracoviensia, 1980, Volume: 22, Issue:3-4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aminopyrine; Amylases; Antipyrine; Ascorbic Acid; Aspartate Aminotransferases; Chlorpropamide; Clinical Enzyme Tests; Diazepam; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Erythromycin; Female; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Pemoline; Phenylbutazone; Poland; Salicylates

1980
Hepatic glucose-6-phosphatase activity in non-insulin dependent diabetics. Effect of enzyme-inducing drugs.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:4

    Topics: Aged; Antipyrine; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Enzyme Induction; Female; Glipizide; Glucose-6-Phosphatase; Humans; Liver; Liver Glycogen; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Middle Aged; Phenobarbital

1984
Comparative placental transport of oral hypoglycemic agents in humans: a model of human placental drug transfer.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Antipyrine; Biological Transport; Chlorpropamide; Chromatography, High Pressure Liquid; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Maternal-Fetal Exchange; Models, Biological; Molecular Weight; Placenta; Pregnancy; Regression Analysis; Tolbutamide

1994