antipyrine and carbamazepine

antipyrine has been researched along with carbamazepine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19909 (21.43)18.7374
1990's9 (21.43)18.2507
2000's12 (28.57)29.6817
2010's10 (23.81)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Blake, JF; Curatolo, WJ; Lombardo, F1
Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Conradi, R; Lee, PH; Shanmugasundaram, V1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Petruch, F; Schüppel, RV1
Beastall, GH; Brodie, MJ; Forrest, G; Larkin, JG; Lloyd, P; Lowrie, JI; McKee, PJ; Park, BK1
Bachmann, KA; Forney, RB; Jauregui, L; Martin, M; Nunlee, M; Schwartz, J1
Elyas, AA; Patsalos, PN; Zakrzewska, JM1
Büchsel, R; Kohl, D; Kreiten, K; Matern, S; Wietholtz, H; Zysset, T1
Brodie, MJ; Butler, E; Larkin, JG; McLellan, A; Munday, A; Sutherland, M1
André, P; Descotes, J; Evreux, JC1
Hopkins, K; Houston, JB; Morselli, PL; Rowland, M; Shaw, PN; Thiercelin, JF1
Moreland, TA; Park, BK; Rylance, GW1
Brodie, MJ; Connell, JM; Gordon, S; Rapeport, WG1
Hedges, A; Makki, KA; Perucca, E; Richens, A; Ruprah, M; Wilson, JF1
Agnew, E; Brodie, MJ; Macphee, GJ; McColl, KE; Murray, T; Park, BK; Scobie, G; Thompson, GG1
Arvela, P; Hartikainen, AL; Herva, R; Partanen, T; Pelkonen, O; Pienimäki, P; Vähäkangas, K1
Airaksinen, KE; Isojärvi, JI; Mustonen, JN; Myllylä, VV; Pakarinen, AJ; Pelkonen, O; Rautio, A1
Dieterle, W; Flesch, G; Lloyd, P1
Bachmann, KA; Jauregui, L1
Heberer, T; Mersmann, P; Scheytt, TJ1
Brümmer, J; Paschke, A; Schüürmann, G1
Benotti, MJ; Brownawell, BJ1
Kusakabe, O; Tran, NH; Urase, T1
Kuroda, K; Murakami, M; Muramatsu, Y; Oguma, K; Takada, H; Takizawa, S1
Hübner, U; Jekel, M; Miehe, U1
Kirchler, CG; Meischl, F; Rainer, M; Stuppner, SE1
Brenčič, M; Koroša, A; Mali, N1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1

Reviews

2 review(s) available for antipyrine and carbamazepine

ArticleYear
Pharmacokinetic drug interactions with macrolide antibiotics.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 15, Issue:6

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipyrine; Carbamazepine; Drug Interactions; Ergot Alkaloids; Erythromycin; Humans; Kinetics; Pharmaceutical Preparations; Theophylline; Troleandomycin

1985
Clinical pharmacology and pharmacokinetics of oxcarbazepine.
    Epilepsia, 1994, Volume: 35 Suppl 3

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Antipyrine; Carbamazepine; Child; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Kidney Diseases; Kinetics; Liver; Oxcarbazepine

1994

Trials

2 trial(s) available for antipyrine and carbamazepine

ArticleYear
A double-blind comparison of conventional and controlled-release carbamazepine in healthy subjects.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:3

    Topics: Adult; Antipyrine; Biological Availability; Carbamazepine; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Male; Psychomotor Performance; Time Factors

1989
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
    Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3

    Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid

1993

Other Studies

38 other study(ies) available for antipyrine and carbamazepine

ArticleYear
Computation of brain-blood partitioning of organic solutes via free energy calculations.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics

1996
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
    Journal of medicinal chemistry, 1998, Dec-03, Volume: 41, Issue:25

    Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship

1998
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
    Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Effects of anticonvulsive treatment on drug elimination in man. Induction of liver hydroxylating enzyme system by diphenylhydantoin and carbamazepine].
    Bibliotheca psychiatrica, 1975, Issue:151

    Topics: Adult; Antipyrine; Bilirubin; Carbamazepine; Creatinine; Epilepsy; Female; Half-Life; Humans; Hydroxylation; Liver; Male; Middle Aged; Phenytoin; Time Factors; Trigeminal Neuralgia

1975
Lack of enzyme induction with oxcarbazepine (600 mg daily) in healthy subjects.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:1

    Topics: Adult; Antipyrine; Carbamazepine; Enzyme Induction; Half-Life; Hormones; Humans; Hydrocortisone; Liver; Male; Mixed Function Oxygenases; Oxcarbazepine; Sex Hormone-Binding Globulin

1991
The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:5

    Topics: Antipyrine; Carbamazepine; Glucuronosyltransferase; Humans; Liver; Lorazepam; Male; Metabolic Clearance Rate; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Polycyclic Compounds; Quinidine; Smoking; Theophylline; Valproic Acid

1990
Dose dependent enzyme induction by oxcarbazepine?
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:2

    Topics: Aged; Anticonvulsants; Antipyrine; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Liver; Male; Middle Aged; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia

1990
Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Aged; Antipyrine; Caffeine; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Hydrocortisone; Male; Middle Aged; Phenytoin; Valproic Acid

1989
Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:6

    Topics: Adult; Antipyrine; Biotransformation; Carbamazepine; Drug Interactions; Half-Life; Humans; Kinetics; Male; Phenytoin; Saliva

1985
Microsomal enzyme induction in children: the influence of carbamazepine treatment on antipyrine kinetics, 6 beta-hydroxycortisol excretion and plasma gamma-glutamyltranspeptidase activity.
    British journal of clinical pharmacology, 1982, Volume: 14, Issue:6

    Topics: Adolescent; Antipyrine; Carbamazepine; Child; Enzyme Induction; gamma-Glutamyltransferase; Half-Life; Humans; Hydrocortisone; Kinetics; Microsomes; Saliva

1982
Changes in circulating thyroid hormones during short-term hepatic enzyme induction with carbamazepine.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:4

    Topics: Adult; Antipyrine; Carbamazepine; Chromatography, High Pressure Liquid; Enzyme Induction; Half-Life; Humans; Liver; Male; Microsomes, Liver; Oxygenases; Thyroid Hormones; Thyroxine-Binding Proteins; Time Factors

1984
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:3

    Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid

1984
Effects of cimetidine on carbamazepine auto- and hetero-induction in man.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Adult; Antipyrine; Carbamazepine; Cimetidine; Half-Life; Humans; Leukocytes; Male; Time Factors

1984
Carbamazepine and its metabolites in human perfused placenta and in maternal and cord blood.
    Epilepsia, 1995, Volume: 36, Issue:3

    Topics: Antipyrine; Biological Transport; Blood; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; Mass Spectrometry; Maternal-Fetal Exchange; Placenta; Pregnancy

1995
Thyroid and myocardial function after replacement of carbamazepine by oxcarbazepine.
    Epilepsia, 1995, Volume: 36, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Antipyrine; Carbamazepine; Cytochrome P-450 Enzyme System; Echocardiography; Epilepsy; Female; Follow-Up Studies; Heart Function Tests; Humans; Liver; Male; Oxcarbazepine; Prospective Studies; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine; Ventricular Function

1995
Mobility of pharmaceuticals carbamazepine, diclofenac, ibuprofen, and propyphenazone in miscible-displacement experiments.
    Journal of contaminant hydrology, 2006, Feb-01, Volume: 83, Issue:1-2

    Topics: Adsorption; Antipyrine; Carbamazepine; Diclofenac; Geologic Sediments; Ibuprofen; Silicon Dioxide; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Water Supply

2006
Silicone rod extraction of pharmaceuticals from water.
    Analytical and bioanalytical chemistry, 2007, Volume: 387, Issue:4

    Topics: Antipyrine; Carbamazepine; Diclofenac; Ibuprofen; Pharmaceutical Preparations; Silicones; Time Factors; Water

2007
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
    Environmental pollution (Barking, Essex : 1987), 2009, Volume: 157, Issue:3

    Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical

2009
The characteristics of enriched nitrifier culture in the degradation of selected pharmaceutically active compounds.
    Journal of hazardous materials, 2009, Nov-15, Volume: 171, Issue:1-3

    Topics: Antipyrine; Bacteria; Biodegradation, Environmental; Bioreactors; Carbamazepine; Chemistry, Pharmaceutical; Clofibric Acid; Diclofenac; Nitrogen; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification

2009
Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers.
    Environmental science & technology, 2012, Feb-07, Volume: 46, Issue:3

    Topics: Antipyrine; Caffeine; Carbamazepine; Chromatography, Gas; Cosmetics; DEET; Drug Combinations; Environmental Monitoring; Escherichia coli; Groundwater; Mass Spectrometry; Salicylamides; Sewage; Terpenes; Tokyo; Toluidines; Water Movements; Water Pollutants, Chemical; Water Pollution

2012
Optimized removal of dissolved organic carbon and trace organic contaminants during combined ozonation and artificial groundwater recharge.
    Water research, 2012, Nov-15, Volume: 46, Issue:18

    Topics: Antipyrine; Carbamazepine; Carbon; Filtration; Groundwater; Metoprolol; Organic Chemicals; Ozone; Primidone; Sulfamethoxazole; Triazoles; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification

2012
Comparative study of substituted poly(4-vinylbenzyl chloride/ethylene glycol dimethacrylate) sorbents for enrichment of selected pharmaceuticals and estrogens from aqueous samples.
    Journal of hazardous materials, 2018, 08-05, Volume: 355

    Topics: Adsorption; Antipyrine; Carbamazepine; Estradiol; Estriol; Estrogens; Estrone; Ibuprofen; Methacrylates; Naproxen; Polyethylene Glycols; Polymerization; Polyvinyls; Water Pollutants, Chemical; Water Purification

2018
Estimating the transport parameters of propyphenazone, caffeine and carbamazepine by means of a tracer experiment in a coarse-gravel unsaturated zone.
    Water research, 2020, May-15, Volume: 175

    Topics: Antipyrine; Caffeine; Carbamazepine; Groundwater; Water Movements; Water Pollutants, Chemical

2020
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021