antipyrine has been researched along with caffeine in 180 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 91 (50.56) | 18.7374 |
| 1990's | 31 (17.22) | 18.2507 |
| 2000's | 37 (20.56) | 29.6817 |
| 2010's | 19 (10.56) | 24.3611 |
| 2020's | 2 (1.11) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, T; Nakajima, M; Nishioka, T | 1 |
| Fujiwara, H; Kai, J; Masuda, T; Nakamura, K; Ueda, I | 1 |
| Blake, JF; Curatolo, WJ; Lombardo, F | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bas, D; Bruneau, P; Chipot, C; Dorison-Duval, D; Moreau, S | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 2 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Akamatsu, M | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Freiberg, N; Gustafsson, B; Hellem, S; Huitfeldt, B; Nord, PG; Persson, G | 1 |
| Pasricha, JS | 1 |
| Böhme, P; Keip, R | 1 |
| Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
| Hill, RC; van Graffenried, B | 1 |
| Bengtsson, U | 2 |
| Passananti, GT; Shively, CA; Vesell, ES | 1 |
| Fukuda, Y; Iwaki, R; Kaizukaya, F; Kitagawa, H | 1 |
| Beubler, E; Lembeck, F | 1 |
| Kakac, B; Ryska, M; Sarsunova, M | 1 |
| Andres, R; Cohen, BH; Norris, AH; Shock, NW; Tobin, JD; Vestal, RE | 1 |
| Alsar Ortiz, MJ; Soto Alvarez, J | 1 |
| Michaelis, HC; Schoel, G; Sharifi, S | 1 |
| Kusec, Z; Marković, S | 1 |
| Hutson, PR; Mutch, RS | 1 |
| Cruccu, G; Ferracuti, S; Innocenti, P; Leardi, MG; Prandi, P | 1 |
| Aboul Khier, A; el Sadek, M; el Shanawany, A; Rücker, G | 2 |
| Weiss, M | 1 |
| Boyet, S; Dumont, I; Nehlig, A; Pereira de Vasconcelos, A | 1 |
| Everson, GT; Lewis, F; Rector, WG; Robertson, AD | 1 |
| Cooksley, WG; Halliday, JW; McIvor, C; Murphy, TL; Powell, LW; Yap, A | 1 |
| Avramova, J | 1 |
| Büchsel, R; Kohl, D; Kreiten, K; Matern, S; Wietholtz, H; Zysset, T | 1 |
| Clerc, JT; Kosmeas, N | 1 |
| Tománková, H; Vasatová, M | 1 |
| Kala, H; Mank, R; Richter, M | 1 |
| La Cascia, C; Mascarella, A; Migneco, G; Navetta, A; Tripi, S | 1 |
| Døssing, M; Loft, S; Poulsen, HE | 1 |
| Bosco, U; Castelli, F; Cosentina, R; Milone, V; Rosaschino, F | 1 |
| Horváth, T; Jávor, T; Rechenbach, C; Traeger, A | 1 |
| Cooksley, WG; George, J; Halliday, JW; Murphy, T; Powell, LW; Roberts, R | 1 |
| Preisig, R | 1 |
| Eigendorf, HG; Hüttner, A | 1 |
| Vesell, ES | 1 |
| Page, JG; Vesell, ES | 1 |
| Sugimoto, I | 2 |
| Pietras, RJ; Wright, EM | 2 |
| Krepinský, J; Stiborova, J | 1 |
| Reiter, W | 1 |
| Oldendorf, WH | 1 |
| Cohn, VH; Sieber, SM; Wynn, WT | 1 |
| Naess, K | 2 |
| Oesch, M; Sahli, M | 1 |
| Gabka, J; Schwietzer, CH | 1 |
| Kincaid-Smith, P; Nanra, RS | 1 |
| Frankendal, B | 1 |
| Campiglio, A | 1 |
| Maickel, RP; Snodgrass, WR | 1 |
| Rabindranath, G | 1 |
| Samková, M | 1 |
| Hill, RC; Turner, P | 1 |
| Anderson, M; Smart, GA; Wilkinson, R | 1 |
| Haefelfinger, P; Ritter, H; Schmidli, B | 1 |
| Rehse, K | 1 |
| Levy, G | 1 |
| Raymann, F | 1 |
| Faust, B | 1 |
| De Santis, A; Re-Garbagnati, V | 1 |
| Ahrenbergová, M; Fischer, R; Prokupek, J; Vondrácek, V | 1 |
| Drtil, J; Sandz, Z | 1 |
| Hsiu, HC; Shih, TB; Wang, KT | 1 |
| Ingbar, SH; Pasternak, DP; Socolow, EL | 1 |
| Levine, J; Weber, JD | 1 |
| Hata, S; Sano, H; Tomioka, S; Yamakawa, M | 1 |
| Krynyckyj, V; Sedivec, V | 1 |
| Johansson, S | 1 |
| Døssing, M | 1 |
| Chan, HL | 1 |
| Perlík, F | 1 |
| Granberg-Ohman, I; Hjerpe, A; Johansson, S | 1 |
| Kalow, W | 1 |
| Anderson, KE; Buening, MK; Conney, AH; Fortner, JG; Kappas, A; Pantuck, CB; Pantuck, EJ | 1 |
| De Ritis, G; De Rossi, P; Diamanti, E; Lauretti, MC; Maggio, F; Marchionni, G; Morabito, F; Roscioni, C | 1 |
| Even-Adin, D; Vanherweghem, JL | 1 |
| Maier-Lenz, H; Ringwelski, L; Windorfer, A | 1 |
| Kocan, A; Ulicná, O; Volmut, J | 1 |
| Johansson, SL | 1 |
| Daniel, V; Howard, M; Nanra, RS | 1 |
| Monshouwer, M; Nijmeijer, SM; Pijpers, A; Van Miert, AS; Verheijden, JH; Witkamp, RF | 1 |
| Arvela, P; Klebovich, I; Pelkonen, O; Rautio, A; Salonpää, P; Sotaniemi, EA | 1 |
| Berry, EM; Caraco, Y; Levy, M; Zylber-Katz, E | 1 |
| Bacracheva, N; Drenska, A; Gorantcheva, J; Tyutyulkova, N; Vlahov, V | 1 |
| Boothe, DM; Brown, SA; Calvin, JA; Corrier, DE; Cullen, JM; Green, RA; Jenkins, WL | 1 |
| Everson, GT; Rector, WG; Robertson, AD | 1 |
| Zollinger, HU | 2 |
| Biber, A; Dienel, A | 1 |
| Hummel, T; Kobal, G; Kraetsch, HG; Kussat, R; Lötsch, J | 1 |
| Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
| Danilov, AB; Vornovskaia, OV | 1 |
| Bouhsain, Z; de la Guardia, M; Garrigues, S | 1 |
| Everson, GT; Marsano, L; McKinley, C; Showalter, R; Shrestha, R; Vivian, B; Wilner, K | 1 |
| Bronner, T; Everson, GT; McKinley, C; Russ, P; Scherzinger, A; Sherstha, R; Showalter, R | 1 |
| Alsar, MJ; Soto, J | 1 |
| Danilov, AB; Poliakova, LV; Tuter, NV | 1 |
| Breimer, DD; Tanaka, E | 1 |
| Carson, SW; Early, JJ; Frye, RF; Matzke, GR; Straka, RJ | 1 |
| Hund, E; Massart, DL; Smeyers-Verbeke, J | 1 |
| Baker, AB; Gao, L; Ramzan, I | 1 |
| Dinç, E; Kökdil, G; Onur, F | 1 |
| Burdan, F; Siezieniewska, Z; Urbanowicz, Z | 1 |
| Kiersch, TA; Minić, MR | 1 |
| Burdan, F | 2 |
| Abe, K; Abe, M; Horiike, N; Kumagi, T; Michitaka, K; Nakanishi, S; Okura, I; Onji, M; Yamagami, T; Yamashita, H | 1 |
| Fu, CM; Huang, J; Huang, XR; Liu, WN; Song, WS; Wang, SX; Zhang, YS; Zhang, ZH | 1 |
| NYKANEN, L; SJOSTROM, E | 1 |
| IDESTROM, CM | 1 |
| SCHEIBL, F; WACHTER, H | 1 |
| CUSSINI, G; GALLIANI, A | 1 |
| IINUMA, I; MORITA, K | 1 |
| SIEGWAN, NA | 1 |
| FRUHMANN, G; TERPLAN, M | 1 |
| BUESSOW, H | 1 |
| MONTANINI, I; PRIOLI, G | 1 |
| BOTTKE, H; GUENTHNER, W | 1 |
| MIRECKI, GB | 1 |
| DINIC, M | 1 |
| KAMP, W | 1 |
| JASINSKI, B | 1 |
| KRISCHEK, J | 1 |
| Ivanovic, D; Jancic, B; Malenovic, A; Medenica, M; Misljenovic, Dj | 1 |
| Aboul-Enein, HY; Baleanu, D; Dinç, E | 1 |
| Abou-Shakra, F; Crowther, D; Jensen, BP; Smith, C; Wilson, ID | 1 |
| FAHRNI, R | 1 |
| Gilbert-López, B; Llorent-Martínez, EJ; Molina-Díaz, A; Ortega-Barrales, P | 1 |
| Emre, D; Ozaltin, N | 1 |
| Dou, Y; Liu, T; Qu, N; Ren, Y; Zou, T | 1 |
| Boskovic, M; Injac, R; Karljikovic-Rajic, K; Prijatelj, M; Srdjenovic, B; Strukelj, B | 1 |
| Jasti, B; Kulkarni, U; Li, X; Mahalingam, R; Pather, SI | 1 |
| Benotti, MJ; Brownawell, BJ | 1 |
| Copanaki, E; Deller, T; Korkotian, E; Schonfeld, E; Segal, M; Vlachos, A | 1 |
| Knudsen, LE; Mose, T; Poulsen, MS; Rytting, E | 1 |
| Chocholous, P; Satínský, D; Sklenárová, H; Solich, P | 1 |
| Kuroda, K; Murakami, M; Muramatsu, Y; Oguma, K; Takada, H; Takizawa, S | 1 |
| Mimura, H; Nasu, M; Nemoto, T; Sako, K | 1 |
| Cui, J; Li, J; Li, R; Lin, W; Ling, X; Yang, H; Yu, N; Zhang, J | 1 |
| Jiang, JG; Song, GS; Zhang, XR; Zhang, YH | 1 |
| Brabcová, I; Chocholouš, P; Maroušková, A; Šatínský, D; Solich, P | 1 |
| Høiseth, G; Karinen, R; Rogde, S; Svendsen, KO; Vindenes, V | 1 |
| Brenčič, M; Koroša, A; Mali, N | 1 |
| Hamdy, AM; Ibrahim, H; Merey, HA; Saad, AS | 1 |
8 review(s) available for antipyrine and caffeine
| Article | Year |
|---|---|
Prevention of renal disease.
Topics: Anti-Glomerular Basement Membrane Disease; Antipyrine; Caffeine; Chronic Disease; Female; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Diseases; Kidney Neoplasms; Kidney Transplantation; Lithium; Phenacetin; Pyelonephritis; Solvents; Uremia | 1979 |
Polygenic factors controlling drug response.
Topics: Adult; Animals; Antipyrine; Caffeine; Dicumarol; Environment; Ethanol; Female; Genetic Variation; Half-Life; Halothane; Humans; Isoniazid; Male; Metabolic Clearance Rate; Mice; Middle Aged; Nortriptyline; Pharmaceutical Preparations; Phenylbutazone; Pregnancy; Smoking; Twins | 1974 |
Chronic effect of analgesics on the kidney.
Topics: Aminopyrine; Analgesics; Animals; Antipyrine; Aspirin; Caffeine; Chronic Disease; Drug Combinations; Drug Synergism; Female; Humans; Kidney; Kidney Diseases; Kidney Papillary Necrosis; Male; Mefenamic Acid; Middle Aged; Nephritis; Phenacetin; Pyrazoles; Substance-Related Disorders; Time Factors | 1972 |
[Filling of drugs into gelatine capsules in pharmacies].
Topics: Acetanilides; Antipyrine; Aspirin; Bicarbonates; Bismuth; Caffeine; Capsules; Codeine; Dosage Forms; Methods; Nitrates; Pharmacies; Phosphates; Quinine; Salicylates; Sodium; Starch; Sulfates; Technology, Pharmaceutical | 1969 |
Noninvasive assessment of microsomal enzyme activity in occupational medicine: present state of knowledge and future perspectives.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; gamma-Glutamyltransferase; Glucaric Acid; Humans; Hydrocortisone; Microsomes, Liver; Occupational Medicine | 1984 |
In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease.
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Erythromycin; Humans; Liver Diseases; Liver Function Tests; Trimethadione | 1997 |
Potential use of pharmacological markers to quantitatively assess liver function during liver transplantation surgery.
Topics: Adult; Antipyrine; Biomarkers; Breath Tests; Caffeine; Coloring Agents; Galactose; Humans; Indocyanine Green; Lidocaine; Liver; Liver Function Tests; Liver Transplantation; Postoperative Period; Reference Values | 2000 |
The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).
Topics: Adult; Antipyrine; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Phenacetin; Placebo Effect; Pyridones; Single-Blind Method; Toothache | 2002 |
14 trial(s) available for antipyrine and caffeine
| Article | Year |
|---|---|
A model for evaluating the analgesic effect of a new fixed ratio combination analgesic in patients undergoing oral surgery.
Topics: Adult; Analgesics; Antipyrine; Aspirin; Caffeine; Dextropropoxyphene; Drug Combinations; Drug Evaluation; Female; Humans; Male; Pain, Postoperative; Parasympatholytics; Phenothiazines; Tooth Extraction; Tooth, Impacted | 1979 |
Headache as a model for testing mild analgesics.
Topics: Adult; Aminopyrine; Analgesics; Antipyrine; Aspirin; Barbiturates; Caffeine; Clinical Trials as Topic; Dihydroergotamine; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Headache; Humans; Male; Placebos; Quinazolines | 1978 |
[Electric stimulation of the dental pulp in the evaluation of the central effect of analgesics].
Topics: Adult; Analgesics; Antipyrine; Benzocaine; Caffeine; Dental Pulp; Diphenhydramine; Diphenylacetic Acids; Dipyrone; Double-Blind Method; Drug Combinations; Drug Evaluation; Electric Stimulation; Ethylmorphine; Humans; Pain Measurement; Sensory Thresholds | 1990 |
[Clinical testing of a new analgesic combination on cancer patients in chronic pain].
Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Dextropropoxyphene; Female; Genital Neoplasms, Female; Humans; Middle Aged; Pain; Placebos; Time Factors | 1973 |
Clinical trial of a new analgesic.
Topics: Analgesics; Antipyrine; Caffeine; Clinical Trials as Topic; Humans; Phenacetin; Phenazines; Placebos | 1968 |
A comparison of codeine compound and "saridone" in the pain of rheumatoid arthritis.
Topics: Adult; Aged; Antipyrine; Arthritis, Rheumatoid; Caffeine; Clinical Trials as Topic; Codeine; Female; Humans; Male; Middle Aged; Phenacetin; Placebos | 1970 |
[Clinical evaluation of analgesics].
Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Phenobarbital | 1984 |
[Comparison of the clinical activity of 2 analgesic formulations].
Topics: Adult; Analgesics; Antipyrine; Caffeine; Clinical Trials as Topic; Drug Combinations; Female; Humans; Lactose; Pain; Phenacetin; Quinine | 1981 |
Antipyrine, coumarin and glipizide affect n-acetylation measured by caffeine test.
Topics: Acetylation; Adult; Analysis of Variance; Antipyrine; Caffeine; Coumarins; Diabetes Mellitus, Type 2; Female; Glipizide; Humans; Hypoglycemic Agents; Male; Middle Aged; Uracil; Xanthines | 1995 |
Caffeine pharmacokinetics in obesity and following significant weight reduction.
Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Body Mass Index; Caffeine; Female; Humans; Male; Middle Aged; Obesity; Weight Loss | 1995 |
Comparative bioavailability of two oral metamizole formulations. Influence of the acetylation phenotype.
Topics: Acetylation; Adult; Antipyrine; Biological Availability; Bulgaria; Caffeine; Cross-Over Studies; Dipyrone; Female; Humans; Male; Phenotype; Therapeutic Equivalency | 1995 |
Pharmacokinetics of losigamone, a new antiepileptic drug, in healthy male volunteers.
Topics: Administration, Oral; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Aspartate Aminotransferases; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Furans; Humans; Male | 1996 |
Analgesic effects of propyphenazone in comparison to its combination with caffeine.
Topics: Administration, Oral; Adult; Analgesia; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Synergism; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Evoked Potentials, Somatosensory; Female; Humans; Male; Nasal Mucosa; Pain | 1996 |
Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity.
Topics: Acetylation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Antitussive Agents; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Dextromethorphan; Diabetes Mellitus, Type 2; Female; Half-Life; Humans; Liver; Male; Middle Aged; Phenotype; Prospective Studies | 2000 |
158 other study(ies) available for antipyrine and caffeine
| Article | Year |
|---|---|
Hydrogen-bonding parameter and its significance in quantitative structure--activity studies.
Topics: Acetylcholinesterase; Anesthetics; Benzene Derivatives; Benzenesulfonates; Carbamates; Chemical Phenomena; Chemistry; Chemistry, Physical; Hydrogen Bonding; Models, Biological; Models, Chemical; Phenoxyacetates; Solubility; Structure-Activity Relationship | 1977 |
Thermodynamic aspects of hydrophobicity and the blood-brain barrier permeability studied with a gel filtration chromatography.
Topics: Blood-Brain Barrier; Chromatography, Gel; Hydrogen Bonding; Micelles; Permeability; Solubility; Thermodynamics | 1996 |
Computation of brain-blood partitioning of organic solutes via free energy calculations.
Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics | 1996 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Rational determination of transfer free energies of small drugs across the water-oil interface.
Topics: Alkanes; Antipyrine; Caffeine; Computer Simulation; Ganciclovir; Glucose; Pharmaceutical Preparations; Solubility; Water | 2002 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water | 2006 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Drugs causing fixed eruptions.
Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phenacetin; Phenobarbital; Pyridones; Sulfadiazine; Sulfanilamides; Tetracycline | 1979 |
[Phenomenology of antipyresis. A study on Fortalidon].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Fever; Humans | 1977 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Failure of cola nut chewing to alter antipyrine disposition in normal male subjects from a small town in South Central Pennsylvania.
Topics: Adult; Africa, Western; Antipyrine; Caffeine; Half-Life; Humans; Male; Metabolic Clearance Rate; Nuts; Pennsylvania; Saliva | 1979 |
[Studies on drug interaction of combined drug. I. Toxicological interaction among isopropylantipyrine, allylisopropylacetylurea, Phenacetin and caffeine on acute toxicity in rats (author's transl)].
Topics: Animals; Antipyrine; Caffeine; Drug Combinations; Drug Interactions; Female; Lethal Dose 50; Male; Phenacetin; Rats; Urea | 1977 |
Methylxanthines and intestinal drug absorption.
Topics: Animals; Antipyrine; Caffeine; Female; Intestinal Absorption; Jejunum; Male; Pharmaceutical Preparations; Rats; Regional Blood Flow; Salicylates; Theophylline; Tritium; Urea; Water | 1976 |
[Study on the effect of detection with iodine on the determination of aromatic compounds after their chromatographic separation, XII].
Topics: Aminopyrine; Antipyrine; Barbiturates; Caffeine; Chromatography, Thin Layer; Iodine; Mass Spectrometry; Theophylline | 1976 |
Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Alcohol Drinking; Antipyrine; Body Water; Caffeine; Coffee; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Regression Analysis; Smoking; Tea | 1975 |
[The assessment of liver microsomal oxidative capacity via caffeine and antipyrine elimination in patients with chronic active hepatitis: preliminary results].
Topics: Adult; Antipyrine; Caffeine; Female; Hepatitis, Chronic; Humans; Liver Function Tests; Male; Microsomes, Liver; Middle Aged; Oxidation-Reduction; Reproducibility of Results | 1992 |
Rhabdomyolysis after suicidal ingestion of an overdose of caffeine, acetaminophen and phenazone as a fixed-dose combination (Spalt N).
Topics: Acetaminophen; Adult; Antipyrine; Caffeine; Creatine Kinase; Drug Combinations; Drug Overdose; Humans; Male; Myoglobin; Rhabdomyolysis; Suicide, Attempted; Tablets | 1991 |
Determination of butalbital, caffeine and propyphenazone in pharmaceutical preparations by gas chromatography method.
Topics: Antipyrine; Barbiturates; Caffeine; Chromatography, Gas; Reference Standards; Tablets | 1991 |
Stability of antipyrine plus caffeine in intravenous solution.
Topics: Antipyrine; Caffeine; Drug Stability; Drug Therapy, Combination; Injections, Intravenous; Solutions | 1991 |
Quantitative determination of analgesic mixture of phenazone, phenacetin and caffeine in the presence of some of their degradation products.
Topics: Analgesics; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Combinations; Phenacetin | 1991 |
Determination of the components of analgesic mixtures using high-performance thin-layer chromatography.
Topics: Acetaminophen; Analgesics; Antipyrine; Ascorbic Acid; Caffeine; Chromatography, High Pressure Liquid; Phenacetin; Phenylephrine | 1990 |
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Ketanserin; Lidocaine; Liver Diseases; Metronidazole; Nomifensine; Triamterene | 1990 |
Effects of caffeine, L-phenylisopropyladenosine and their combination on local cerebral blood flow in the rat.
Topics: Adenosine; Animals; Antipyrine; Blood Pressure; Caffeine; Cerebrovascular Circulation; Drug Interactions; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1990 |
Renal sodium retention complicating alcoholic liver disease: relation to portosystemic shunting and liver function.
Topics: Adult; Antipyrine; Ascites; Caffeine; Cholic Acid; Cholic Acids; Humans; Kidney; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Male; Portal System; Sodium | 1990 |
The effect of smoking on caffeine elimination: implications for its use as a semiquantitative test of liver function.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Liver Function Tests; Male; Middle Aged; Smoking; Substance Withdrawal Syndrome | 1988 |
Simultaneous determination of propyphenazone, paracetamol and caffeine in blood by high-performance liquid chromatography.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Rats | 1989 |
Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism.
Topics: Adolescent; Adult; Aged; Antipyrine; Caffeine; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Hydrocortisone; Male; Middle Aged; Phenytoin; Valproic Acid | 1989 |
[A quick DC method for simultaneous quantitative determination of paracetamol, caffeine, phenobarbital and propyphenazone in plasma].
Topics: Acetaminophen; Antipyrine; Caffeine; Humans; Phenobarbital | 1989 |
[Densitometric determination of propyphenazone, paracetamol, guaiacol glycerol ether, caffeine and acetylsalicylic acid in analgesic-antipyretic preparations with thin-layer chromatography].
Topics: Acetaminophen; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Densitometry; Drug Combinations; Guaifenesin | 1989 |
[Preparation of oral sustained-action preparations with a base of biologically degradable polymers. 2. Preparation of matrix tablets with a base of polylactic acid].
Topics: Antipyrine; Caffeine; Chemistry, Pharmaceutical; Delayed-Action Preparations; Lactates; Lactic Acid; Polyesters; Polymers; Solubility; Tablets | 1989 |
[Cytolytic episodes during cirrhosis].
Topics: Antipyrine; Anxiety Disorders; Barbiturates; Caffeine; Cholestasis; Drug Therapy, Combination; Female; Haloperidol; Humans; Liver Cirrhosis; Maprotiline; Middle Aged; Recurrence; Temazepam; Time Factors | 1986 |
Influence of age and consumption of tobacco, alcohol and caffeine on antipyrine clearance.
Topics: Adult; Age Factors; Alcohol Drinking; Antipyrine; Caffeine; Humans; Male; Middle Aged; Saliva; Smoking | 1988 |
[A new analgesic in pediatric practice: Sig 8304].
Topics: Adolescent; Analgesics; Antipyrine; Benzoates; Caffeine; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Female; Humans; Infant; Male; Pain | 1986 |
Beta-adrenoceptor blocking drugs and cytochrome P-450: the influence of propranolol treatment on caffeine, antipyrine, D-glucaric acid and indocyanine green elimination in patients with hepatic disorders.
Topics: Adult; Antipyrine; Caffeine; Cytochrome P-450 Enzyme System; Female; Glucaric Acid; Humans; Indocyanine Green; Liver Diseases, Alcoholic; Male; Middle Aged; Propranolol | 1986 |
Influence of alcohol and caffeine consumption on caffeine elimination.
Topics: Adult; Alcohol Drinking; Antipyrine; Caffeine; Coffee; Half-Life; Humans; Kinetics; Male | 1986 |
[Foreign substances as indicators of liver function].
Topics: Aminopyrine; Antipyrine; Breath Tests; Caffeine; Cytosol; Humans; Indocyanine Green; Liver; Liver Circulation; Liver Function Tests; Portal System | 1985 |
[Simultaneous determination of propyphenazone, caffeine and codeine in drug mixtures by reverse phase HPLC].
Topics: Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Spectrophotometry, Ultraviolet | 1986 |
Genetic control of dicumarol levels in man.
Topics: Adult; Antipyrine; Caffeine; Centrifugation; Coffee; Dicumarol; Female; Genetics, Medical; Humans; Male; Methylcholanthrene; Middle Aged; Nicotine; Phenylbutazone; Pregnancy; Prothrombin Time; Smoking; Spectrophotometry; Twins | 1968 |
Studies on complexes. XIV. Effect of complex formation on drug absorption from alimentary tract. (5). Enhancing the absorption of certain drugs by complex formation.
Topics: Animals; Antipyrine; Caffeine; Indoles; Intestinal Absorption; Intestine, Small; Niacinamide; Rats; Salicylates; Theophylline | 1969 |
Non-electrolyte probes of membrane structure in ADH-treated toad urinary bladder.
Topics: Amides; Animals; Antipyrine; Biological Transport; Bufo marinus; Butyrates; Caffeine; Glycols; In Vitro Techniques; Membranes; Niacinamide; Permeability; Propylene Glycols; Urinary Bladder; Vasopressins | 1974 |
Routes of nonelectrolyte permeation across epithelial membranes.
Topics: Acetamides; Alcohols; Animals; Antipyrine; Bufo marinus; Caffeine; Choroid Plexus; Epithelium; Erythritol; Gallbladder; Glycerol; Kinetics; Mannitol; Mathematics; Membranes; Niacinamide; Organ Specificity; Permeability; Rabbits; Rana catesbeiana; Sucrose; Urea; Urinary Bladder; Water | 1974 |
[Determination of amidopyrine, antipyrine and caffeine in mixtures using a volumetric solution of perchloric acid].
Topics: Aminopyrine; Antipyrine; Caffeine; Chemistry, Pharmaceutical; Perchlorates | 1966 |
[Effect of non-aqueous elution agents on the behavior of extremely weak bases in ion exchange chromatography using an example of pharmaceutical agent mixture].
Topics: 1-Propanol; Antipyrine; Benzamides; Benzoates; Caffeine; Catechols; Central Nervous System Stimulants; Chromatography, Ion Exchange; Chromatography, Thin Layer; Ethanol; Methanol; Salicylamides; Solvents; Spectrophotometry; Tablets; Theophylline; Ultraviolet Rays; Water | 1969 |
Brain uptake of metabolites and drugs following carotid arterial injections.
Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats | 1971 |
The entry of foreign compounds into the thoracic duct lymph of the rat.
Topics: Acids; Alcohols; Amines; Aniline Compounds; Animals; Anthracenes; Antipyrine; Benzoates; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Chromatography, Thin Layer; Chylomicrons; DDT; Digoxin; Estradiol; Isoniazid; Lymph; Male; Phenanthrenes; Salicylates; Testosterone; Thoracic Duct; Time Factors; Tritium | 1974 |
[Combinated oral antiasthmatics--how effective are they? An invitation to discussion].
Topics: Administration, Oral; Antipyrine; Asthma; Caffeine; Drug Combinations; Ephedrine; Humans; Parasympatholytics; Theophylline | 1974 |
[Gas chromatographic determination of phenacetin, caffeine, antipyrine and dimethylaminoantipyrine in pharmaceutical specialties].
Topics: Antipyrine; Caffeine; Chromatography, Gas; Dimethylamines; Phenacetin | 1974 |
[Intensification of effect using a combination of analgesic drugs in a split-tablet].
Topics: Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Mandelic Acids; Pain; Salicylamides; Salicylates | 1974 |
[Determination of the N-methyl group in organic substances on the micro and decimomilligram scale].
Topics: Acetanilides; Aminopyrine; Antipyrine; Caffeine; Diphenhydramine; Ephedrine; Indicators and Reagents; Methylation; Microchemistry; Theobromine; Theophylline | 1973 |
Physicochemical factors in maternal-fetal distribution of drugs.
Topics: Amphetamine; Aniline Compounds; Animals; Antipyrine; Aspirin; Atropine; Benzoates; Caffeine; Carbon Radioisotopes; Decamethonium Compounds; Female; Gestational Age; Half-Life; Hexamethonium Compounds; Inulin; Maternal-Fetal Exchange; Mescaline; Pentobarbital; Pharmaceutical Preparations; Pregnancy; Rats; Reserpine; Tetraethylammonium Compounds; Time Factors; Tritium | 1973 |
[Risks in long-term treatment with analgesics].
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Caffeine; Diuresis; Drug Combinations; Humans; Kidney Diseases; Mental Disorders; Phenacetin; Substance-Related Disorders | 1973 |
Phenacetin and renal pelvic carcinoma.
Topics: Age Factors; Antipyrine; Caffeine; Female; Humans; Kidney Failure, Chronic; Kidney Neoplasms; Kidney Pelvis; Male; Papilloma; Phenacetin; Salicylates; Sex Factors; Substance-Related Disorders; Sweden; Time Factors | 1974 |
Growth-hormone deficiency in iatrogenic hypothyroidism.
Topics: Adult; Antipyrine; Body Height; Caffeine; Dwarfism, Pituitary; Growth Hormone; Humans; Hypothyroidism; Iodine; Male; Phenacetin; Plant Extracts; Puberty | 1972 |
[Quantitative determination of phenacetin, isopropylantipyrine, caffeine, and persedon in a pharmaceutical combination preparation].
Topics: Analgesics; Antipyrine; Caffeine; Chemistry, Pharmaceutical; Phenacetin | 1964 |
[Drug analysis by nuclear magnetic resonance. 3. Qualitative and quantitative analysis of analgesic combination preparations].
Topics: Aminopyrine; Antipyrine; Caffeine; Magnetic Resonance Spectroscopy; Phenacetin; Spectrum Analysis | 1970 |
Effect of complex formation on drug absorption.
Topics: Amides; Animals; Antipyrine; Body Weight; Caffeine; Cyprinidae; Drug Interactions; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Prednisone; Propionates; Rats; Salicylamides; Secobarbital; Solubility; Surface-Active Agents; Time Factors | 1971 |
[Pain from the viewpoint of the general practitioner. Experiences with a new analgesic].
Topics: Adolescent; Adult; Aged; Amobarbital; Analgesics; Antipyrine; Caffeine; Family Practice; Humans; Middle Aged; Pain; Phenazines; Pyrazines | 1969 |
[Ambulatory experiences with a new analgesic].
Topics: Adult; Aged; Ambulatory Care; Aminopyrine; Amobarbital; Analgesics; Antipyrine; Caffeine; Female; Humans; Male; Middle Aged; Pain; Propylamines; Psychophysiologic Disorders | 1969 |
[Proposed methods of analysis of F.G.N. preparations. Tablets of an aminophenazone compound].
Topics: Antipyrine; Caffeine; Chromatography; Pharmaceutic Aids; Phenacetin; Tablets | 1967 |
Recent patterns of addiction in Czechoslovakia.
Topics: Adult; Analgesics; Antipyrine; Aspirin; Barbiturates; Bronchodilator Agents; Caffeine; Czechoslovakia; Ephedrine; Female; Hospitals, Psychiatric; Humans; Hypnotics and Sedatives; Meprobamate; Phenmetrazine; Procaine; Psychoses, Substance-Induced; Substance-Related Disorders | 1968 |
[Changes in the gastric mucosa following the use of various antiasthmatics and analgesics-antipyretics].
Topics: Adult; Analgesics; Antipyrine; Barbiturates; Bronchodilator Agents; Caffeine; Chronic Disease; Gastric Mucosa; Gastritis; Humans; Male; Phenacetin; Pyrazoles; Substance-Related Disorders | 1968 |
Studies on complexes. XII. Effect of complex formation on drug absorption from the alimentary tract. (3).
Topics: Animals; Antipyrine; Caffeine; Intestinal Absorption; Kinetics; Rats; Sulfonamides | 1968 |
Polyamide layer chromatography of some antipyretics.
Topics: Acetanilides; Amides; Aminopyrine; Analgesics; Antipyrine; Aspirin; Caffeine; Chromatography, Thin Layer; Indomethacin; Oxyphenbutazone; Phenacetin; Salicylates | 1969 |
Synergistic interaction of phenazone and iodide on thyroid hormone biosynthesis in the rat.
Topics: Animals; Antipyrine; Asthma; Caffeine; Chromatography, Paper; Digitalis; Diiodotyrosine; Drug Synergism; Goiter; Iodides; Iodine; Iodine Isotopes; Male; Monoiodotyrosine; Myxedema; Phenacetin; Plants, Medicinal; Plants, Toxic; Rats; Strophanthins; Thyroglobulin; Thyroid Gland | 1969 |
Determination of antipyrine in combinations with other drugs.
Topics: Antipyrine; Benzocaine; Caffeine; Chemistry, Pharmaceutical; Salicylates | 1965 |
Quantum chemical considerations on the stability of aqueous solution of an electron acceptor such as menadione.
Topics: Antipyrine; Caffeine; Chemical Phenomena; Chemistry, Physical; Theophylline; Vitamin K | 1965 |
[Mental disorders in chronic Yastyl poisoning].
Topics: Adult; Antipyrine; Asthma; Caffeine; Ephedrine; Humans; Male; Middle Aged; Procaine; Psychoses, Substance-Induced | 1966 |
Cardiovascular lesions in Sprague-Dawley rats induced by long-term treatment with caffeine.
Topics: Acetaminophen; Animals; Antipyrine; Caffeine; Cardiovascular Diseases; Heart; Male; Myocardial Infarction; Myocardium; Necrosis; Phenacetin; Polyarteritis Nodosa; Rats; Rats, Inbred Strains; Splanchnic Circulation | 1981 |
Fixed drug eruptions. A study of 20 occurrences in Singapore.
Topics: Adult; Aged; Ampicillin; Analgesics; Antipyrine; Aspirin; Caffeine; Chlorothiazide; Drug Combinations; Drug Eruptions; Female; Humans; Male; Methimazole; Middle Aged; Phenacetin; Phenolphthaleins; Promethazine; Pyrazoles; Pyrazolones; Pyridones; Singapore; Tetracyclines | 1984 |
Sister-chromatid exchanges and chromosomal aberrations in rats treated with phenacetin, phenazone and caffeine.
Topics: Animals; Antipyrine; Blood Cells; Caffeine; Chromosome Aberrations; Drug Therapy, Combination; Mutagenicity Tests; Mutagens; Phenacetin; Rats; Sister Chromatid Exchange; Specific Pathogen-Free Organisms | 1980 |
Pharmacoanthropology: drug metabolism.
Topics: Antipyrine; Asian People; Biotransformation; Caffeine; Ethnicity; Humans; White People | 1984 |
Regulation of human drug metabolism by dietary factors.
Topics: Adult; Antipyrine; Biotransformation; Caffeine; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Half-Life; Humans; Metabolic Clearance Rate; Oxidation-Reduction; Pharmaceutical Preparations; Theobromine; Theophylline; Vegetables | 1980 |
Epidemiology of analgesic nephropathy in Belgium.
Topics: Acetaminophen; Analgesics; Antipyrine; Aspirin; Belgium; Caffeine; Drug Combinations; Humans; Kidney Diseases; Phenacetin | 1982 |
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)].
Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets | 1981 |
[Possibility of caffeine occurring as an unknown drug in the determination of antipyrine in plasma].
Topics: Antipyrine; Caffeine; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans | 1981 |
Carcinogenicity of analgesics: long-term treatment of Sprague-Dawley rats with phenacetin, phenazone, caffeine and paracetamol (acetamidophen).
Topics: Acetaminophen; Adenocarcinoma; Analgesics; Animals; Antipyrine; Caffeine; Carcinogens; Carcinoma, Squamous Cell; Kidney; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Phenacetin; Rats; Rats, Inbred Strains; Sarcoma; Time Factors; Urinary Tract; Urologic Diseases | 1981 |
Analgesic nephropathy induced by common proprietary mixtures.
Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Caffeine; Drug Combinations; Female; Humans; Kidney Papillary Necrosis; Nonprescription Drugs; Phenacetin; Rats; Salicylamides; Substance-Related Disorders | 1980 |
Selective effects of a bacterial infection (Actinobacillus pleuropneumoniae) on the hepatic clearances of caffeine, antipyrine, paracetamol, and indocyanine green in the pig.
Topics: Acetaminophen; Actinobacillus Infections; Actinobacillus pleuropneumoniae; Animals; Antipyrine; Caffeine; Creatinine; Indocyanine Green; Liver; Male; Swine | 1995 |
Antipyrine and caffeine dispositions in clinically normal dogs and dogs with progressive liver disease.
Topics: Analysis of Variance; Animals; Antipyrine; Caffeine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Dogs; Female; Liver; Liver Diseases; Male; Reference Values | 1994 |
Sodium retention does not occur at a critical threshold of liver function in alcoholic cirrhosis.
Topics: Antipyrine; Ascites; Blood Volume; Caffeine; Cholic Acid; Cholic Acids; Humans; Liver; Liver Cirrhosis, Alcoholic; Male; Serum Albumin; Sodium | 1994 |
[Scientific raisins from 125 years SMW (Swiss Medical Weekly). Chronic interstitial nephritis in abuse of phenacetin-containing analgesics (Saridon etc.) 1953].
Topics: Antipyrine; Caffeine; Drug Combinations; History, 20th Century; Humans; Nephritis, Interstitial; Phenacetin; Pyridones | 1995 |
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers.
Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin | 1996 |
[Caffetin in the treatment of neck pain and lumbago-sciatica].
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Codeine; Drug Combinations; Drug Evaluation; Humans; Low Back Pain; Neck Pain; Pain Measurement; Sciatica | 1997 |
Clean method for the simultaneous determination of propyphenazone and caffeine in pharmaceuticals by flow injection Fourier transform infrared spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Chemistry, Pharmaceutical; Solvents; Spectroscopy, Fourier Transform Infrared | 1997 |
Quantitative liver function tests define the functional severity of liver disease in early-stage cirrhosis.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Caffeine; Cholic Acid; Cholic Acids; Disease Progression; Female; Humans; Injections, Intravenous; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Prognosis | 1997 |
Postmenopausal estrogen therapy selectively stimulates hepatic enlargement in women with autosomal dominant polycystic kidney disease.
Topics: Antipyrine; Caffeine; Cysts; Estrogen Replacement Therapy; Female; Hormones; Humans; Kidney; Liver; Liver Diseases; Middle Aged; Polycystic Kidney, Autosomal Dominant; Tomography, X-Ray Computed | 1997 |
A pilot study of the effect of antipyrine on caffeine kinetics in six healthy volunteer subjects.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Area Under Curve; Caffeine; Drug Interactions; Female; Half-Life; Humans; Liver; Male; Pilot Projects; Saliva | 1997 |
[The treatment of a complex regional pain syndrome].
Topics: Acetaminophen; Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Cerebrovascular Disorders; Codeine; Combined Modality Therapy; Drug Combinations; Evaluation Studies as Topic; Hand Injuries; Humans; Hyperbaric Oxygenation; Leg Injuries; Nerve Compression Syndromes; Pain Measurement; Reflex Sympathetic Dystrophy; Soft Tissue Injuries | 1997 |
Evaluation of the H-point standard additions method (HPSAM) and the generalized H-point standard additions method (GHPSAM) for the UV-analysis of two-component mixtures.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antipyrine; Atovaquone; Caffeine; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Evaluation Studies as Topic; Models, Chemical; Naphthoquinones; Proguanil; Spectrophotometry, Ultraviolet | 1999 |
Derivative ratio spectra-zero crossing spectrophotometry and LC method applied to the quantitative determination of paracetamol, propyphenazone and caffeine in ternary mixtures.
Topics: Acetaminophen; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Solutions; Spectrophotometry, Ultraviolet; Tablets | 2001 |
Combined effects of acetaminophen, isopropylantipyrine and caffeine on pregnant and nonpregnant liver.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Body Weight; Caffeine; Central Nervous System Stimulants; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Liver; Liver Function Tests; Organ Size; Periodic Acid-Schiff Reaction; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar | 2001 |
Effects of prenatal exposure to combination of acetaminophen, isopropylantipyrine and caffeine on intrauterine development in rats.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic and Fetal Development; Female; Male; Pregnancy; Rats; Rats, Wistar | 2002 |
Drug-induced hepatitis with hepatic granuloma due to saridon.
Topics: Adult; Antipyrine; Biopsy, Needle; Caffeine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Granuloma; Headache; Humans; Immunohistochemistry; Liver Function Tests; Phenacetin; Pyridones; Risk Assessment; Severity of Illness Index | 2002 |
[Determination of naoning pian by multi-wavelength linear regression method].
Topics: Analgesics, Non-Narcotic; Antipyrine; Caffeine; Drug Combinations; Linear Models; Pharmaceutical Preparations; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets | 2001 |
[Chronic interstitial nephritis caused by the abuse of analgetics containing phenacetin (Saridon etc.)].
Topics: Antipyrine; Caffeine; Drug Combinations; Humans; Nephritis; Nephritis, Interstitial; Phenacetin; Pyridones | 1955 |
Ion exchange method for determination of caffeine in presence of antipyrine and phenacetin.
Topics: Aminopyrine; Antipyrine; Caffeine; Health Services; Ion Exchange; Phenacetin | 1958 |
[Phenacetin-phenazone-caffeine addiction. An experimental study].
Topics: Antipyrine; Behavior, Addictive; Caffeine; Phenacetin; Substance-Related Disorders | 1960 |
[On the demonstration of the active substances of saridon].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Caffeine; Drug Combinations; Phenacetin; Pyridones | 1960 |
[Chronic bronchopneumopathy in young and old smokers: therapeutic effectiveness of a multivalent drug].
Topics: Antipyrine; Bronchi; Bronchial Diseases; Caffeine; Digitalis; Digitalis Glycosides; Disease; Lung Diseases; Phenacetin; Smoking; Strophanthins | 1962 |
[Eye diseases caused by internally administered migrenin].
Topics: Antipyrine; Caffeine; Citrates; Exanthema; Eye Diseases; Eyelids; Humans; Keratitis; Optic Neuritis | 1962 |
[CLINICAL TRIAL OF LUNEDON AS AN ANALGESIC FOR ELDERLY PATIENTS].
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Caffeine; Codeine; Geriatrics; Humans; Sweden; Thiazines | 1964 |
[ON THE THERAPY OF BRONCHIAL ASTHMA AND ASTHMATOID BRONCHITIS.SPIROGRAPHIC AND RESPIRATORY FUNCTION STUDIES].
Topics: Antipyrine; Asthma; Bronchitis; Bronchodilator Agents; Caffeine; Humans; Isoproterenol; Respiratory Function Tests; Spirometry | 1964 |
[ON THE PROBLEM OF PSYCHOSES DUE TO ANTIASTHMATIC DRUGS].
Topics: Anti-Asthmatic Agents; Antipyrine; Asthma; Atropine; Caffeine; Digitalis Glycosides; Ephedrine; Hallucinations; Humans; Lobelia; Mental Disorders; Paranoid Disorders; Phenacetin; Psychoses, Substance-Induced; Psychotic Disorders; Strophanthins; Toxicology | 1964 |
[SURFACE TENSION AND THE FORMATION OF MOLECULAR COMPOUNDS. IV. MOLECULAR ASSOCIATIONS OF CAFFEINE].
Topics: Acetanilides; Antipyrine; Aspirin; Benzene; Benzoates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chloral Hydrate; Cinnamates; Research; Resorcinols; Salicylamides; Salicylates; Surface Tension; Urethane | 1964 |
[EXPERIMENTAL STUDIES OF AN ASTHMA POWDER IN A DOUBLE BLIND TRIAL].
Topics: Antipyrine; Asthma; Biomedical Research; Bronchodilator Agents; Caffeine; Double-Blind Method; Drug Therapy; Humans; Metaproterenol; Powders; Respiratory Function Tests | 1964 |
[FURTHER EXPERIENCES WITH VERTEBRAN IN ORTHOPEDIC PRACTICE].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Atropine; Back Pain; Brachial Plexus Neuritis; Caffeine; Drug Therapy; Ergotamine; Humans; Hydrocortisone; Joint Diseases; Osteochondritis; Polymyalgia Rheumatica; Prednisolone; Prednisone; Procaine; Reflex Sympathetic Dystrophy; Spinal Osteophytosis; Spondylitis; Spondylitis, Ankylosing; Strychnine | 1965 |
[DETERMINATION OF ANTIPYRINE, CITRATE AND CAFFINE IN POWDERS AND TABLETS].
Topics: Antipyrine; Caffeine; Citrates; Citric Acid; Powders; Research; Tablets | 1965 |
[The determination of antipyrine and caffeine in the presence of phenacetin with the aid of ion exchange resins].
Topics: Antipyrine; Caffeine; Health Services; Ion Exchange Resins; Phenacetin | 1959 |
[Addenda to our knowledge on the pathogenesis of toxico-hemolytic anemia following the administration of phenacetin (saridon)].
Topics: Anemia; Anemia, Hemolytic; Antipyrine; Caffeine; Drug Combinations; Humans; Phenacetin; Pyridones | 1950 |
[Migraine therapy with migraine kranit].
Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital | 1951 |
Optimization of the RP-HPLC method for multicomponent analgetic drug determination.
Topics: Acetaminophen; Analgesics; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Reference Standards; Spectrophotometry, Ultraviolet; Tablets | 2003 |
Wavelet analysis for the multicomponent determination in a binary mixture of caffeine and propyphenazone in tablets.
Topics: Antipyrine; Caffeine; Chemistry, Pharmaceutical; Spectrophotometry, Ultraviolet; Tablets | 2004 |
High-performance liquid chromatography/inductively coupled plasma mass spectrometry and tandem mass spectrometry for the detection of carbon-containing compounds.
Topics: Antipyrine; Caffeine; Carbon; Chromatography, High Pressure Liquid; Mass Spectrometry; Phenacetin; Solvents; Sulfanilamide; Sulfanilamides | 2004 |
Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antipyrine; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryonic Development; Female; Fetal Development; Fetal Weight; Organ Size; Placenta; Pregnancy; Rats; Rats, Wistar; Toxicity Tests | 2004 |
[Toxic psychoses due to sedormid, saridon and contra-pain].
Topics: Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Hypnotics and Sedatives; Pain; Phenacetin; Psychoses, Substance-Induced; Psychotic Disorders; Pyridones; Urea | 1950 |
Development of a multicommuted flow-through optosensor for the determination of a ternary pharmaceutical mixture.
Topics: Antipyrine; Buffers; Caffeine; Flow Injection Analysis; Methanol; Pharmaceutical Preparations; Reproducibility of Results; Salicylamides; Sensitivity and Specificity; Silica Gel; Silicon Dioxide; Software; Solvents; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical; Water | 2007 |
Simultaneous determination of paracetamol, caffeine and propyphenazone in ternary mixtures by micellar electrokinetic capillary chromatography.
Topics: Acetaminophen; Antipyrine; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Molecular Structure; Reproducibility of Results | 2007 |
Calibration in non-linear NIR spectroscopy using principal component artificial neural networks.
Topics: Antipyrine; Caffeine; Calibration; Citrates; Neural Networks, Computer; Principal Component Analysis; Reference Standards; Regression Analysis; Spectroscopy, Near-Infrared | 2007 |
Determination of caffeine and associated compounds in food, beverages, natural products, pharmaceuticals, and cosmetics by micellar electrokinetic capillary chromatography.
Topics: Acetaminophen; Antipyrine; Aspirin; Beverages; Biological Products; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Codeine; Cosmetics; Food Analysis; Linear Models; Pharmaceutical Preparations; Salicylic Acid; Theobromine; Theophylline | 2008 |
Porcine buccal mucosa as an in vitro model: relative contribution of epithelium and connective tissue as permeability barriers.
Topics: Administration, Buccal; Animals; Antipyrine; Bupivacaine; Buspirone; Caffeine; Cell Membrane Permeability; Connective Tissue Cells; Diffusion; Diffusion Chambers, Culture; Epithelial Cells; Kinetics; Lipid Bilayers; Models, Biological; Mouth Mucosa; Swine; Technology, Pharmaceutical | 2009 |
Microbial degradation of pharmaceuticals in estuarine and coastal seawater.
Topics: Absorption; Antipyrine; Bacteria; Biodegradation, Environmental; Caffeine; Carbamazepine; Cotinine; Diltiazem; Ecology; Endocrine Disruptors; Half-Life; New York; Nifedipine; Pharmaceutical Preparations; Seawater; Solubility; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical | 2009 |
Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons.
Topics: Acetaminophen; Actins; Animals; Animals, Newborn; Antipyrine; Caffeine; Calcium; Cells, Cultured; Codeine; Dendritic Spines; Drug Combinations; Electric Stimulation; Excitatory Amino Acid Agents; Green Fluorescent Proteins; Hippocampus; Microfilament Proteins; Models, Biological; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Transport; Rats; Receptors, AMPA; RNA, Small Interfering; Ryanodine Receptor Calcium Release Channel; Synaptophysin; Transfection | 2009 |
Modeling placental transport: correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion.
Topics: Antipyrine; Benzoic Acid; Caffeine; Cell Line; Cell Membrane Permeability; Female; Glycine; Glyphosate; Humans; Kinetics; Maternal Exposure; Maternal-Fetal Exchange; Models, Biological; Perfusion; Placenta; Pregnancy | 2009 |
Two-column sequential injection chromatography--new approach for fast and effective analysis and its comparison with gradient elution chromatography.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Spectrophotometry, Ultraviolet; Tablets | 2010 |
Assessment of groundwater pollution in Tokyo using PPCPs as sewage markers.
Topics: Antipyrine; Caffeine; Carbamazepine; Chromatography, Gas; Cosmetics; DEET; Drug Combinations; Environmental Monitoring; Escherichia coli; Groundwater; Mass Spectrometry; Salicylamides; Sewage; Terpenes; Tokyo; Toluidines; Water Movements; Water Pollutants, Chemical; Water Pollution | 2012 |
Development of qualitative and quantitative analysis methods in pharmaceutical application with new selective signal excitation methods for 13 C solid-state nuclear magnetic resonance using 1 H T1rho relaxation time.
Topics: Acetaminophen; Antipyrine; beta-Cyclodextrins; Caffeine; Carbon Isotopes; Chemistry, Pharmaceutical; Crystallization; Drug Combinations; Excipients; Indomethacin; Lactose; Magnetic Resonance Spectroscopy; Nifedipine; Pharmaceutical Preparations; Phenacetin; Povidone; Protons; Pyridones; Signal Processing, Computer-Assisted; Technology, Pharmaceutical | 2013 |
Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC-DAD: a cocktail approach.
Topics: Administration, Oral; Animals; Antipyrine; Caffeine; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dapsone; Limit of Detection; Linear Models; Male; Metoprolol; Omeprazole; Piperazines; Random Allocation; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Solid Phase Extraction | 2013 |
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Green chromatography separation of analytes of greatly differing properties using a polyethylene glycol stationary phase and a low-toxic water-based mobile phase.
Topics: Acetaminophen; Acetonitriles; Aminophenols; Antipyrine; Caffeine; Calibration; Chromatography, High Pressure Liquid; Ethylamines; Hydrophobic and Hydrophilic Interactions; Methanol; Polyethylene Glycols; Reproducibility of Results; Tablets; Ultraviolet Rays | 2013 |
A fatal intoxication with phenazone (antipyrine).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Caffeine; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Tandem Mass Spectrometry | 2015 |
Estimating the transport parameters of propyphenazone, caffeine and carbamazepine by means of a tracer experiment in a coarse-gravel unsaturated zone.
Topics: Antipyrine; Caffeine; Carbamazepine; Groundwater; Water Movements; Water Pollutants, Chemical | 2020 |
Simultaneous Determination of Paracetamol, Propyphenazone and Caffeine in Presence of Paracetamol Impurities Using Dual-Mode Gradient HPLC and TLC Densitometry Methods.
Topics: Acetaminophen; Aminophenols; Antipyrine; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Densitometry; Drug Combinations; Drug Contamination; Limit of Detection; Meprobamate; Nitrophenols; Reproducibility of Results; Sensitivity and Specificity; Solvents; Tablets | 2021 |