antipyrine has been researched along with atenolol in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.11) | 18.7374 |
| 1990's | 7 (15.56) | 18.2507 |
| 2000's | 21 (46.67) | 29.6817 |
| 2010's | 11 (24.44) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Ax, F; Bonham, NM; Hallberg, A; Karlén, A; Lennernäs, H; Winiwarter, S | 1 |
| Ghuloum, AM; Jain, AN; Sage, CR | 1 |
| Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S | 1 |
| Ertl, P; Rohde, B; Selzer, P | 1 |
| Artursson, P; Luthman, K; Norinder, U; Stenberg, P | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Caron, G; Ermondi, G | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Chatterjee, J; Gilon, C; Hoffman, A; Kessler, H; Marinelli, L; Ovadia, O; Zahn, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Thorling, CA; Zhang, Q | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Belpaire, FM; Bogaert, MG; Chauvelot-Moachon, L; de Smet, F; Rosseel, MT; Vermeulen, AM; Vynckier, LJ | 1 |
| Hansen, JM; Jørgensen, B; Kayser, L; Perrild, H; Poulsen, HE; Skovsted, L | 1 |
| Baljet, AV; Breimer, DD; Danhof, M; de Boer, AG; van Bree, JB; van Geyt, A | 1 |
| Hutt, HJ; Kirch, W; Kitteringham, NR; Mutschler, E; Ohnhaus, EE; Spahn, H | 1 |
| Daneshmend, TK; Roberts, CJ | 1 |
| Bax, ND; Crewe, K; Lennard, MS; Tucker, GT; Woods, HF | 1 |
| Ahrenstedt, O; Lennernäs, H; Ungell, AL | 1 |
| Abrahamsson, B; Knutson, L; Knutson, TW; Lennernäs, H; Lindahl, A; Sandström, R; Ungell, AL | 1 |
| Fagerholm, U; Lennernäs, H; Lindahl, A | 1 |
| Grudén, AC; Krondahl, E; Lennernäs, H; Lindahl, A; Ungell, AL | 1 |
| Amidon, GL; Hilgendorf, C; Langguth, P; Lipka, E; Regårdh, CG; Spahn-Langguth, H | 1 |
| Chang, P; Hung, DY; Roberts, MS; Siebert, GA | 1 |
| Aungst, B; Dobson, G; Hidalgo, I; Letendre, L; Scott, M | 1 |
| Kataoka, M; Masaoka, Y; Sakuma, S; Tanaka, Y; Yamashita, S | 1 |
| Bansal, T; Jaggi, M; Khar, RK; Mishra, G; Mukherjee, R; Singh, M; Talegaonkar, S | 1 |
| Fontaine, F; Goh, LA; Khlentzos, AM; Liu, X; Nikolovski, J; Roberts, MS; Wang, JY | 1 |
| Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Weiss, M; Zhang, Q | 1 |
| Collares, EF; Vinagre, AM | 1 |
| Funai, Y; Horiuchi, T; Ichijo, K; Inoue, K; Ishihara, M; Kishimoto, H; Moteki, Y; Oda, R; Okada, R; Shirasaka, Y | 1 |
| Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
3 trial(s) available for antipyrine and atenolol
| Article | Year |
|---|---|
Differential effect of continuous administration of beta-adrenoceptor antagonists on antipyrine and phenytoin clearance.
Topics: Adrenergic beta-Antagonists; Adult; Antipyrine; Atenolol; Humans; Male; Metoprolol; Phenytoin; Propranolol | 1989 |
Lack of effect of atenolol on antipyrine clearance.
Topics: Adult; Antipyrine; Atenolol; Drug Interactions; Humans; Kinetics; Male; Metabolic Clearance Rate; Propanolamines | 1982 |
Intestinal drug absorption during induced net water absorption in man; a mechanistic study using antipyrine, atenolol and enalaprilat.
Topics: Adult; Antipyrine; Atenolol; Cell Membrane Permeability; Enalaprilat; Female; Humans; Intestinal Absorption; Jejunum; Male; Pharmaceutical Preparations; Reference Values; Water | 1994 |
42 other study(ies) available for antipyrine and atenolol
| Article | Year |
|---|---|
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
Topics: Humans; Intestinal Absorption; Jejunum; Models, Biological; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship | 1998 |
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance | 2000 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Experimental and computational screening models for the prediction of intestinal drug absorption.
Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Multiple N-methylation by a designed approach enhances receptor selectivity.
Topics: Binding Sites; Drug Design; Integrin alpha5beta1; Integrin alphaVbeta3; Ligands; Methylation; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Platelet Glycoprotein GPIIb-IIIa Complex; Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cations; Cytochrome P-450 Enzyme System; Disease Models, Animal; Emulsions; Fats; Fatty Liver; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of aging on the pharmcokinetics of atenolol, metoprolol and propranolol in the rat.
Topics: Aging; Animals; Antipyrine; Atenolol; Male; Metabolic Clearance Rate; Metoprolol; Orosomucoid; Propranolol; Rats; Rats, Inbred Strains | 1990 |
The unit impulse response procedure for the pharmacokinetic evaluation of drug entry into the central nervous system.
Topics: Acetaminophen; Animals; Antipyrine; Atenolol; Brain; Central Nervous System; Computers; Diffusion; Drug Carriers; Injections, Intravenous; Injections, Intraventricular; Male; Models, Biological; Pharmacokinetics; Rats; Rats, Inbred Strains | 1989 |
Interaction between the beta-adrenoceptor blockers metoprolol and atenolol with amitriptyline and their effects on oxidative liver metabolism.
Topics: Adult; Amitriptyline; Antipyrine; Atenolol; Double-Blind Method; Drug Interactions; Female; Humans; Hydrocortisone; Kinetics; Liver; Male; Metoprolol; Oxidation-Reduction; Random Allocation | 1984 |
The short term effects of propranolol, atenolol and labetalol on antipyrine kinetics in normal subjects.
Topics: Adult; Antipyrine; Atenolol; Drug Interactions; Female; Half-Life; Humans; Kinetics; Labetalol; Male; Propranolol; Sympatholytics | 1982 |
Jejunal permeability and hepatic extraction of fluvastatin in humans.
Topics: Adult; Antipyrine; Atenolol; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Infusions, Intravenous; Intestinal Absorption; Jejunum; Liver; Male; Metoprolol; Perfusion | 1996 |
Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensive Agents; Antipyrine; Atenolol; Biological Transport; Colon; Fatty Acids, Monounsaturated; Fluvastatin; Glucose; Hydrogen-Ion Concentration; Ileum; Indoles; Intestinal Absorption; Jejunum; Levodopa; Membrane Fluidity; Metoprolol; Naproxen; Perfusion; Permeability; Rats; Stereoisomerism; Structure-Activity Relationship | 1997 |
Is the jejunal permeability in rats age-dependent?
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Glucose; Jejunum; Male; Metoprolol; Permeability; Rats; Rats, Sprague-Dawley | 1997 |
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.
Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Membrane Permeability; Cellular Senescence; Coculture Techniques; Furosemide; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoprofen; Mannitol; Metoprolol; Microscopy, Electron; Piroxicam; Reproducibility of Results; Terbutaline | 2000 |
Ion-trapping, microsomal binding, and unbound drug distribution in the hepatic retention of basic drugs.
Topics: Animals; Antipyrine; Atenolol; Hydrogen-Ion Concentration; Liver; Male; Microsomes, Liver; Models, Biological; Propranolol; Rats; Rats, Wistar | 2004 |
Evaluating barriers to bioavailability in vivo: validation of a technique for separately assessing gastrointestinal absorption and hepatic extraction.
Topics: Amoxicillin; Animals; Antipyrine; Area Under Curve; Atenolol; Biological Availability; Gastrointestinal Tract; Intestinal Absorption; Liver; Male; Models, Animal; Propranolol; Rats; Rats, Sprague-Dawley; Testosterone | 2004 |
Site of drug absorption after oral administration: assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract.
Topics: Administration, Oral; Animals; Antipyrine; Atenolol; Cell Membrane Permeability; Intestinal Absorption; Intestinal Mucosa; Male; Membrane Fluidity; Metoprolol; Rats; Rats, Wistar | 2006 |
Concurrent determination of topotecan and model permeability markers (atenolol, antipyrine, propranolol and furosemide) by reversed phase liquid chromatography: utility in Caco-2 intestinal absorption studies.
Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Chromatography, High Pressure Liquid; Drug Stability; Furosemide; Humans; Intestinal Absorption; Permeability; Propranolol; Reproducibility of Results; Sensitivity and Specificity; Topotecan | 2007 |
Influence of perfusate composition on drug disposition in the in-situ perfused rat lung.
Topics: Animals; Antipyrine; Atenolol; Buffers; Carbon Radioisotopes; Deuterium Oxide; Dextrans; Evans Blue; Hydrogen-Ion Concentration; Indicator Dilution Techniques; Lung; Male; Models, Biological; Morpholines; Perfusion; Permeability; Pressure; Propranolol; Rats; Rats, Wistar; Serum Albumin, Bovine; Sucrose | 2009 |
Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
Topics: Adrenergic Antagonists; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Failure; Labetalol; Linear Models; Liver; Liver Cirrhosis; Liver Diseases; Male; Metabolic Clearance Rate; Metoprolol; Microsomes, Liver; Models, Biological; Necrosis; Nonlinear Dynamics; Perfusion; Propranolol; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2012 |
Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats.
Topics: Adrenergic beta-Antagonists; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Butoxamine; Dipyrone; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Ganglionectomy; Gastric Emptying; Male; Models, Animal; Propanolamines; Rats, Wistar; Receptors, Adrenergic, beta; Sympathetic Nervous System | 2016 |
Osmolality of Orally Administered Solutions Influences Luminal Water Volume and Drug Absorption in Intestine.
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Dextrans; Fluorescein-5-isothiocyanate; Intestinal Absorption; Intestinal Mucosa; Male; Osmolar Concentration; Rats; Rats, Wistar; Water | 2017 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |