antipyrine and allopurinol

antipyrine has been researched along with allopurinol in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19908 (29.63)18.7374
1990's0 (0.00)18.2507
2000's15 (55.56)29.6817
2010's4 (14.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bobo, L; Crom, WR; Evans, WE; Relling, MV; Teresi, ME; Webster, SL1
Greene, FE; Passananti, GT; Vesell, ES1
Greene, FE; Page, JG; Passananti, GT; Vesell, ES1
Passananti, GT; Vessell, ES1
Welch, RM1
O'Sullivan, WJ1
Lane, AC; McCoubrey, A; Smith, MH1
Bozal, J; Calvet, F; Ramia, J1
Albaladejo, V; Bournique, B; Lerche-Langrand, C; Martin, H; Sarsat, JP1
Fung, KP; Wu, J; Wu, TW; Zeng, LH1
Akamatsu, H; Mikawa, K; Nishina, K; Niwa, Y; Obara, H1
Chen, YZ; Li, ZR; Yap, CW1
Koizumi, T; Sakaki, S; Shimazaki, S; Tanaka, H1
Haruma, K; Iida, M; Koga, H; Shimizu, K1
Ahmed, M; Hossain, M; Miyajima, K; Muntasir, HA; Nagatomo, T; Nakazawa, M1
Shimizu, M1
Fujio, A; Goto, M; Hara, Y; Kashiwadate, T; Kawagishi, N; Maida, K; Miyagi, S; Miyazawa, K; Murakami, K; Nakanishi, C; Nakanishi, W; Ohuchi, N; Yamaya, H1
Chen, Y; Gao, F; Huang, Z; Li, W; Liao, H; Lu, S; Shi, G; Sun, T; Wang, B; Xu, H; Zhang, Y; Zheng, F; Zhong, S1

Reviews

2 review(s) available for antipyrine and allopurinol

ArticleYear
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays

1971
[Topics of the brain protection in neonate, which has been your better choice, the brain hypothermia or the medicine?].
    No to hattatsu = Brain and development, 2009, Volume: 41, Issue:2

    Topics: Allopurinol; Antioxidants; Antipyrine; Edaravone; Erythropoietin; Free Radical Scavengers; Free Radicals; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Neuroprotective Agents; Oxidative Stress

2009

Other Studies

25 other study(ies) available for antipyrine and allopurinol

ArticleYear
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Simultaneous administration of multiple model substrates to assess hepatic drug clearance.
    Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6

    Topics: Administration, Oral; Adult; Allopurinol; Antipyrine; Drug Interactions; Humans; Indocyanine Green; Infusions, Intravenous; Liver; Lorazepam; Male; Metabolic Clearance Rate

1987
Impairment of drug metabolism in man by allopurinol and nortriptyline.
    The New England journal of medicine, 1970, Dec-31, Volume: 283, Issue:27

    Topics: Adult; Allopurinol; Aniline Compounds; Animals; Antipyrine; Biotransformation; Cytochromes; Dicumarol; Humans; Male; Microsomes, Liver; Morphinans; Nortriptyline; Oxidoreductases; Pharmaceutical Preparations; Rats; Time Factors

1970
Genetic control of drug levels and of the induction of drug-metabolizing enzymes in man: individual variability in the extent of allopurinol and nortriptyline inhibition of drug metabolism.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Adult; Allopurinol; Aniline Compounds; Animals; Antipyrine; Coffee; Cytochromes; Dicumarol; Ethanol; Female; Half-Life; Humans; Kinetics; Male; Mathematics; Metabolism; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Morphinans; Nortriptyline; Oxidoreductases; Pharmacogenetics; Phenobarbital; Phenylbutazone; Pregnancy; Rats; Smoking; Statistics as Topic; Tea; Twins; White People

1971
Drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Allopurinol; Animals; Antipyrine; Blood Coagulation; Dicumarol; Dogs; Drug Interactions; Drug Synergism; Enzyme Induction; Half-Life; Liver; Methods; Oxidoreductases; Phenobarbital; Phenylbutazone; Protein Binding; Prothrombin Time; Time Factors; Tolbutamide

1973
Metabolic side-effects of allopurinol.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Allopurinol; Antipyrine; Azathioprine; Azauridine; Benzothiadiazines; Dicumarol; Diuretics; Drug Synergism; Erythrocytes; Humans; Leukocytes; Mercaptopurine; Orotic Acid; Pentosyltransferases; Pyrimidines; Sodium Chloride Symporter Inhibitors; Thymidine; Xanthine Oxidase

1974
Inhibition of enzymes by alkylsalicylic acids.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5

    Topics: Aldehydes; Animals; Antipyrine; Carbonic Anhydrase Inhibitors; D-Amino-Acid Oxidase; Esterases; Flufenamic Acid; Glucosephosphate Dehydrogenase; Glycyrrhiza; Guinea Pigs; Indomethacin; Phenylacetates; Phenylbutazone; Plants, Medicinal; Rabbits; Rats; Salicylates; Serum Albumin; Succinate Dehydrogenase; Xanthine Oxidase

1970
[Influence of some therapeutic agents on the biosynthesis of uric acid].
    Revista espanola de fisiologia, 1966, Volume: 22, Issue:3

    Topics: Animals; Antipyrine; Benzoates; Chickens; Colchicine; Liver; Phenylbutazone; Rats; Salicylates; Swine; Uric Acid; Xanthine Oxidase

1966
Cryopreserved rat liver slices: a critical evaluation of cell viability, histological integrity, and drug-metabolizing enzymes.
    Cryobiology, 2000, Volume: 41, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Antipyrine; Apoptosis; Biotransformation; Cell Survival; Cryopreservation; Cryoprotective Agents; Dimethyl Sulfoxide; Glutathione; Hepatocytes; Insulin; Liver; Male; Organ Culture Techniques; Organ Preservation Solutions; Oxidation-Reduction; Proteins; Raffinose; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles

2000
MCI-186: further histochemical and biochemical evidence of neuroprotection.
    Life sciences, 2000, Sep-29, Volume: 67, Issue:19

    Topics: Animals; Antipyrine; Brain; Brain Infarction; Creatine Kinase; Cytochrome c Group; Edaravone; Free Radical Scavengers; Free Radicals; Hypoxanthine; Male; Neuroprotective Agents; Propyl Gallate; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Xanthine Oxidase

2000
Effects of edaravone on human neutrophil function.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:3

    Topics: Antipyrine; Calcium; Chemotaxis; Dose-Response Relationship, Drug; Edaravone; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Neutrophils; Phagocytosis; Reactive Oxygen Species; Reference Values; Xanthine; Xanthine Oxidase

2005
Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods.
    Journal of molecular graphics & modelling, 2006, Volume: 24, Issue:5

    Topics: Adult; Algorithms; Allopurinol; Antipyrine; Carbidopa; Chlorpheniramine; Fendiline; Humans; Male; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Quinazolines; Reproducibility of Results; Statistics as Topic; Thiophenes; Tocainide

2006
The therapeutic efficacy of edaravone in extensively burned rats.
    Archives of surgery (Chicago, Ill. : 1960), 2006, Volume: 141, Issue:10

    Topics: Animals; Antipyrine; Burns; Disease Models, Animal; Edaravone; Free Radical Scavengers; Free Radicals; Lung; Male; Malondialdehyde; Prospective Studies; Random Allocation; Rats; Rats, Wistar; Xanthine Oxidase

2006
Microcirculatory changes in experimental mesenteric longitudinal ulcers of the small intestine in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:11

    Topics: Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Cytokines; Disease Models, Animal; Disease Progression; Edaravone; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Ileal Diseases; Ileum; Indomethacin; Laser-Doppler Flowmetry; Male; Mesentery; Microcirculation; Peroxidase; Rats; Rats, Wistar; Regional Blood Flow; Ulcer

2007
Differential inhibition by oxygen radicals of vasoactive amines-induced contractions in the porcine coronary artery.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:7

    Topics: Acetylcholine; Animals; Antipyrine; Calcium; Coronary Vessels; Edaravone; Free Radicals; Histamine; Hydrogen Peroxide; Serotonin; Swine; Vasoconstriction; Xanthine; Xanthine Oxidase

2007
Edaravone, a free radical scavenger, improves the graft viability on liver transplantation from non-heart-beating donors in pigs.
    Transplantation proceedings, 2014, Volume: 46, Issue:4

    Topics: Adenosine; Allopurinol; Animals; Antipyrine; Biomarkers; Cold Ischemia; Cytoprotection; Edaravone; Free Radical Scavengers; Glutathione; Graft Survival; Insulin; Liver; Liver Transplantation; Male; Models, Animal; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Swine; Time Factors; Tissue and Organ Harvesting; Tissue Survival; Warm Ischemia

2014
Effect of N-n-butyl haloperidol iodide on ROS/JNK/Egr-1 signaling in H9c2 cells after hypoxia/reoxygenation.
    Scientific reports, 2015, Jul-02, Volume: 5

    Topics: Acetylcysteine; Antipyrine; Cell Hypoxia; Cell Line; Early Growth Response Protein 1; Edaravone; Gene Expression Regulation; Haloperidol; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Xanthine Oxidase

2015