antipyrine and 4-hydroxy-2-nonenal

antipyrine has been researched along with 4-hydroxy-2-nonenal in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's12 (66.67)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andoh, A; Araki, Y; Asano, N; Bamba, S; Fujiyama, Y; Ishizuka, I; Yokono, T; Yoshikawa, K1
Andoh, A; Araki, Y; Fujiyama, Y1
Ishii, H; Kameyama, K; Kitamura, K; Kurita, S; Nakamoto, N; Saito, H; Saito, Y; Tada, S1
Abe, K; Hayashi, T; Horiuchi, S; Kato, S; Nagano, I; Omori, N; Sato, K; Zhang, W1
Hashikura, Y; Ikeda, U; Ise, H; Ishida, A; Miyagawa, S; Nakayama, J; Suzuki, F; Takahashi, M1
Komine-Kobayashi, M; Liu, M; Mizuno, Y; Tanaka, R; Urabe, T; Zhang, N1
Hashimoto, M; Mikuriya, T; Okuda, T; Shimogori, H; Sugahara, K; Takemoto, T; Takeno, K; Tanaka, K; Yamashita, H1
Akishita, M; Eto, M; Hasegawa, H; Kozaki, K; Nagai, K; Toba, K; Xi, H; Yu, W1
Mikuriya, T; Shimogori, H; Takemoto, T; Yamashita, H1
Miyamoto, R; Ogihara, T; Shimakawa, S; Suzuki, S; Tamai, H1
Maekawa, H; Masuda, Y; Matsunobu, T; Onozato, K; Shiotani, A; Tanabe, T; Tsuda, H1
Hashimoto, S; Ito, H; Itoh, T; Nishida, S; Satou, T; Tsubaki, M1
Hashimoto, S; Imano, M; Ito, H; Itoh, T; Nishida, S; Satou, T; Tsubaki, M1
Kadokami, T; Maeda, T; Makino, N; Oyama, J; Satoh, S; Suematsu, N; Sugano, M1
Miller, JW; Murakami, Y; Roh, MI; Thanos, A; Vavvas, DG1
Hashimoto, T; Hasumi, K; Honda, K; Nobe, K; Shibata, K1
Fukui, M; Miyamoto, R; Nomura, S; Shimakawa, S; Tamai, H1
Li, F; Li, J; Liu, X; Wang, Q; Yang, R1

Other Studies

18 other study(ies) available for antipyrine and 4-hydroxy-2-nonenal

ArticleYear
The free radical scavenger edaravone suppresses experimental closed duodenal loop-induced acute pancreatitis in rats.
    International journal of molecular medicine, 2003, Volume: 12, Issue:1

    Topics: Aldehydes; Amylases; Animals; Antipyrine; Ascitic Fluid; Edaravone; Free Radical Scavengers; Malondialdehyde; Pancreatitis, Acute Necrotizing; Rats

2003
The free radical scavenger edaravone suppresses experimental dextran sulfate sodium-induced colitis in rats.
    International journal of molecular medicine, 2003, Volume: 12, Issue:1

    Topics: Aldehydes; Animals; Antipyrine; Colitis; Edaravone; Free Radical Scavengers; Interleukin-6; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley

2003
A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury.
    Free radical research, 2003, Volume: 37, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Disease; Alanine Transaminase; Aldehydes; Animals; Antipyrine; Apoptosis; Cell Death; Cytokines; Deoxyguanosine; Edaravone; Free Radical Scavengers; Growth Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-10; Interleukin-4; Interleukin-6; Liver; Male; Models, Chemical; Necrosis; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2003
Extension of ischemic therapeutic time window by a free radical scavenger, Edaravone, reperfused with tPA in rat brain.
    Neurological research, 2004, Volume: 26, Issue:3

    Topics: Aldehydes; Animals; Antipyrine; Brain Ischemia; Cell Count; Deoxyadenosines; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Edaravone; Fibrinolytic Agents; Free Radical Scavengers; Glycation End Products, Advanced; Hemorrhage; Immunohistochemistry; In Situ Nick-End Labeling; Male; Rats; Rats, Wistar; Survival Analysis; Tetrazolium Salts; Time Factors; Tissue Plasminogen Activator

2004
MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats.
    Transplant international : official journal of the European Society for Organ Transplantation, 2005, Volume: 18, Issue:7

    Topics: Alanine Transaminase; Aldehydes; Animals; Antipyrine; Chemokines; Cytokines; Edaravone; Free Radical Scavengers; Immunohistochemistry; Liver; Macrophages; Male; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Time Factors

2005
Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Antipyrine; Brain; Brain Ischemia; Deoxyguanosine; DNA Damage; Edaravone; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Immunoblotting; Immunohistochemistry; Inflammation; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reperfusion Injury; Time Factors; Tyrosine

2005
Post-exposure administration of edaravone attenuates noise-induced hearing loss.
    European journal of pharmacology, 2005, Oct-17, Volume: 522, Issue:1-3

    Topics: Aldehydes; Animals; Antipyrine; Auditory Threshold; Brain Stem; Cell Count; Edaravone; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory, Outer; Hearing Loss; Immunohistochemistry; Male; Noise; Organ of Corti; Phytotherapy

2005
Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis.
    Atherosclerosis, 2007, Volume: 191, Issue:2

    Topics: Aldehydes; Animals; Antipyrine; Apolipoproteins E; Apoptosis; Atherosclerosis; Cells, Cultured; Cholesterol, Dietary; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Endothelial Cells; Free Radical Scavengers; Hydrogen Peroxide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidants; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors; Tyrosine; Vascular Cell Adhesion Molecule-1

2007
Edaravone protects the vestibular periphery from free radical-induced toxicity in response to perilymphatic application of (+/-)-alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid.
    European journal of pharmacology, 2007, Jan-12, Volume: 554, Issue:2-3

    Topics: Aldehydes; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipyrine; Edaravone; Excitatory Amino Acid Agonists; Free Radical Scavengers; Free Radicals; Guinea Pigs; Immunohistochemistry; Infusion Pumps; Male; Nystagmus, Pathologic; Reflex, Vestibulo-Ocular; Vestibular Diseases; Vestibular Function Tests; Vestibule, Labyrinth

2007
Edaravone prevents kainic acid-induced neuronal death.
    Brain research, 2008, May-13, Volume: 1209

    Topics: Aldehydes; Animals; Antipyrine; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Edaravone; Epilepsy; Free Radical Scavengers; Glutathione; Kainic Acid; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Status Epilepticus; Treatment Outcome

2008
Therapeutic effect of edaravone on inner ear barotrauma in the guinea pig.
    Neurochemistry international, 2009, Volume: 54, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antipyrine; Barotrauma; Cochlea; Deoxyguanosine; Ear, Inner; Edaravone; Evoked Potentials, Auditory, Brain Stem; Female; Free Radical Scavengers; Guinea Pigs; Hearing Loss; Immunohistochemistry; Organ of Corti; Pressure; Spiral Ganglion; Stria Vascularis

2009
The novel free radical scavenger, edaravone, increases neural stem cell number around the area of damage following rat traumatic brain injury.
    Neurotoxicity research, 2009, Volume: 16, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult Stem Cells; Aldehydes; Animals; Antipyrine; Behavior, Animal; Brain Injuries; Cell Count; Cell Differentiation; Cell Proliferation; Cells, Cultured; Deoxyguanosine; Disease Models, Animal; DNA, Single-Stranded; Edaravone; ELAV Proteins; Free Radical Scavengers; Linear Models; Lipid Peroxidation; Male; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Statistics, Nonparametric; Time Factors

2009
Edaravone protects against apoptotic neuronal cell death and improves cerebral function after traumatic brain injury in rats.
    Neurochemical research, 2010, Volume: 35, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antipyrine; Apoptosis; Behavior, Animal; Brain Injuries; Deoxyguanosine; DNA, Single-Stranded; Edaravone; ELAV Proteins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Maze Learning; Rats; Rats, Wistar

2010
Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo.
    Heart and vessels, 2010, Volume: 25, Issue:5

    Topics: Acetylcholine; Aged; Aldehydes; Antipyrine; Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Echocardiography, Doppler; Edaravone; Endothelium, Vascular; Female; Free Radical Scavengers; Free Radicals; Humans; Infusions, Intra-Arterial; Isosorbide Dinitrate; Japan; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Vasodilation; Vasodilator Agents

2010
Edaravone, an ROS scavenger, ameliorates photoreceptor cell death after experimental retinal detachment.
    Investigative ophthalmology & visual science, 2011, Jun-01, Volume: 52, Issue:6

    Topics: Aldehydes; Animals; Antipyrine; Blotting, Western; Caspases; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Edaravone; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Free Radical Scavengers; In Situ Nick-End Labeling; Oxidative Stress; Photoreceptor Cells, Vertebrate; Protein Carbonylation; Rats; Rats, Inbred BN; Reactive Oxygen Species; Retinal Detachment

2011
Neuroprotective mechanisms of SMTP-7 in cerebral infarction model in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 384, Issue:1

    Topics: Aldehydes; Animals; Antipyrine; Benzopyrans; Brain; Cerebral Infarction; Disease Models, Animal; Edaravone; Ferrous Compounds; Free Radical Scavengers; Gene Expression; Lipid Peroxidation; Male; Mice; Mice, Inbred Strains; NADPH Oxidases; Neuroprotective Agents; Pyrrolidinones; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Thiobarbituric Acid Reactive Substances; Tissue Plasminogen Activator

2011
3-Methyl-1-phenyl-2-pyrazolin-5-one or N-acetylcysteine prevents hippocampal mossy fiber sprouting and rectifies subsequent convulsive susceptibility in a rat model of kainic acid-induced seizure ceased by pentobarbital.
    Brain research, 2014, Nov-24, Volume: 1590

    Topics: Acetylcysteine; Aldehydes; Animals; Anticonvulsants; Antipyrine; Cell Survival; Edaravone; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Glutathione; Kainic Acid; Male; Mossy Fibers, Hippocampal; Pentobarbital; Rats; Rats, Sprague-Dawley; Seizures

2014
Edaravone injection ameliorates cognitive deficits in rat model of Alzheimer's disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:11

    Topics: Acetylcholinesterase; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antipyrine; Choline O-Acetyltransferase; Dentate Gyrus; Disease Models, Animal; Edaravone; Immunohistochemistry; Maze Learning; Neuroprotective Agents; Nootropic Agents; Oxidative Stress; Peptide Fragments; Random Allocation; Rats, Wistar; Spatial Memory

2015