Page last updated: 2024-08-24

antineoplaston a10 and 2-piperidone

antineoplaston a10 has been researched along with 2-piperidone in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199022 (26.51)18.7374
1990's21 (25.30)18.2507
2000's13 (15.66)29.6817
2010's11 (13.25)24.3611
2020's16 (19.28)2.80

Authors

AuthorsStudies
Bronowicz, A; Kochman, A1
Eriguchi, N; Hara, H; Ishii, K; Nishida, H; Sasaki, K; Sugihara, S; Tanaka, N; Tsuda, H; Yoshimura, S1
Green, S1
Copland, JA; Hendry, LB; Muldoon, TG; Wood, JC1
Michalska, D1
Wang, H; Xu, W; Yuan, Y2
Hara, H; Hashimoto, K; Kakegawa, T; Koga, T; Shintomi, Y; Tanaka, M; Tsuda, H1
Tsuda, H1
Hendry, LB; Muldoon, TG1
Eriguchi, N; Hara, H; Ikeda, I; Inoue, S; Nakayama, T; Nishida, H; Ohishi, K; Tsuda, H; Yoshida, H1
Ashraf, AQ; Burzynski, SR; Kampalath, BN; Liau, MC1
Burzynski, B; Burzynski, SR; Kampalath, BN; Liau, MC1
Burzynski, B; Burzynski, SR; Liau, MC; Szopa, M1
Burzynski, SR; Copland, JA; Hendry, LB; Lehner, AF; Muldoon, TG1
Copland, JA; Hendry, LB; Lehner, AF; Muldoon, TG1
Hara, H; Hirohata, M; Maruiwa, H; Shigemori, M; Sugita, Y; Tsuda, H1
Chu, CK; Copland, JA; Hendry, LB; Mahesh, VB1
Chu, CK; Copland, JA; Hendry, LB; Mahesh, VB; Pantazis, CG; Wood, JC; Wrenn, RW1
Burzynski, SR2
Eriguchi, N; Hara, H; Kumabe, T; Nishida, H; Sugita, Y; Tsuda, H; Yoshida, H1
Hara, H; Iemura, A; Sata, M; Tsuda, H; Uchida, M; Yamana, K1
D'Avignon, DA; Revelle, LK; Wilson, JA1
Reepmeyer, JC; Revelle, LK; Tang, Y; Wilson, JA1
Cheon, SH; Cho, WJ; Choi, BG; Choi, SU; Chung, BH; Kim, OY; Lee, CO1
Ames, MM; Buckner, JC; Cascino, TL; Figg, WD; Lim, S; Malkin, MG; Reed, E; Reid, JM; Tong, WP1
Choi, BG; Choi, SU; Chung, BH; Lee, CO; Seo, HK1
Abou-Zeid, L; Badria, F; Khafagy, W; Mabed, M1
Abou-Zeid, L; Al-Nashar, E; Badria, F; El-Awadi, M; Hawas, S; Mabed, M1
Abdelal, AM; Abou-Zeid, LA; Badria, FA; el-Ashmawy, MB; el-Mowafy, AM; Hendry, LB1
Axler, ML; Bestak, M; Burzynski, SR; Janicki, TJ; Jurida, GF; Khan, MI; Lewy, RI; Paszkowiak, JK; Szymkowski, BG; Weaver, RA1
Akagi, Y; Araki, Y; Hara, H; Kumabe, T; Matono, K; Ogata, Y; Saitsu, H; Sata, M; Shirouzu, K; Tsuda, H1
LIDEN, K1
AUBEL, G1
DUNNEBACKE, TH; MATTERN, CF2
FISENKO, Ia; SERGIENKO, IN; SUSLOVA, EM1
FRIEDRICH, W; RADL, H1
DURNOV, LA; LEBEDEV, VI1
LINDROOS, B; NYYSSOENEN, O; SETAELAE, K1
NOZDRACHEV, AD; SHICHKO, GA; SYRENSKII, VI1
KORANTZES, S1
FILIPPKIN, MA1
LEYNS, J1
HAYBITTLE, JL1
MATTERN, CF1
PARKER, AJ1
Matono, K; Ogata, Y; Shirouzu, K1
Hammer, MR; Jonas, WB1
Burzynski, SR; Janicki, T; Jurida, G; Khan, M; Larisma, CB; Lewy, RI; Paszkowiak, J; Szymkowski, B; Weaver, R1
Bestak, M; Burzynski, SR; Janicki, TJ; Jurida, GF; Khan, MI; Lewy, RI; Szymkowski, BG; Weaver, RA1
Burzynski, SR; Dolgopolov, V; Janicki, T; Jurida, G; Khan, M; Szymkowski, B; Weaver, RA1
Fujii, T; Kawamura, D; Kuwano, M; Miwa, K; Nakamura, AM; Shirouzu, K; Tayama, K; Toh, U; Tsuda, H; Yamaguchi, M; Yamana, H; Yokoyama, G1
Burzynski, B; Burzynski, SR; Janicki, TJ; Weaver, RA1
Farokhzad, OC; Gu, F; Langer, R; Mann, N; Radovic-Moreno, AF; Teply, BA; Wang, A; Zhang, L1
Cho, SW; Kim, AR; Kim, DI; Lee, JY; Shin, SW; Um, SH1
Abnous, K; Danesh, NM; Ramezani, M; Sarreshtehdar Emrani, A; Tabrizian, K; Taghdisi, SM; Zandkarimi, M1
Burzynski, GS; Burzynski, SR; Janicki, TJ; Marszalek, A2
Clerici, CA; Massimino, M1
Di Rocco, C1
Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Uchida, S; Ushijima, M1
Chen, W; He, W; Huang, M; Weng, Y; Xie, J; Yan, Y; Zhang, Y; Zheng, K; Zhu, Y1
Abdelbary, AA; Aboumanei, MH; El-Kolaly, MT; Ibrahim, IT; Tadros, MI2
Chen, CY; Da Silva, J; Hatakeyama, W; Kihara, H; Kim, DM; Kondo, H; Lee, C; Nagai, M; Nagai, S; Nojiri, T1
Cui, B; Cui, L; Dong, F; Li, K; Liang, Z; Liu, P; Ma, C; Wu, X; Zheng, H1
Berra, S; Borrell, C; Pasarín, MI; Rocha, KB; Rodríguez-Sanz, M1
Ge, X; Guo, C; King, GJ; Li, G; Li, H; Li, Z; Liu, K; Tian, Y; Wan, M; Wang, B; Wang, J; Yin, S1
Huang, M; Huang, Z; Li, F; Liu, X; Ma, K; Niu, J; Yang, W; Yu, X1
Blayney, A; Campbell, D; Chalasani, A; Chan, E; Ho, D; McCullough, J; Wake, E; Walters, K; Winearls, J1
Fang, F; Ji, T; Li, C; Liu, J; Liu, L; Teng, Z; Wang, J; Wu, J; Yang, Y; Zhang, W; Zhang, X1
Bartlewski, PM; Ekanayake, DL; Małopolska, MM; Schwarz, T; Tuz, R1
Abid, C; Chiab, N; Gargouri-Bouzid, R; Ghazala, I; Karray, F; Nouri-Ellouz, O; Samet, M; Sayadi, S1
Contreras, J; Duan, A; Fudge, JL; Kelly, EA; Vassell, R1
Chen, L; Duan, S; He, Z; Jin, W; Li, Q; Li, Y; Liu, Q; Ma, S; Qin, M; Shi, L; Wang, J; Yang, F; Zhang, J; Zhang, W; Zhang, Y; Zhao, Y1
Border, EC; Pumphrey, NJ; Simister, PC; Vieira, JF1
Hu, Y; Song, J; Wang, L; Wang, Y; Zhang, Y; Zhao, W; Zhong, M1
Dong, P; Feng, S; Jin, L; Li, Z1
Bansal, C; Crespi, M; Gupta, A; Mathur, S; Rao, S; Sorin, C1
deLaforcade, AM; Molitoris, AM; Pfaff, A; Rozanski, EA1
Chen, T; Chen, W; Chen, Y; Cun, Z; Du, L; Gan, Q; Han, M; He, J; Li, J; Liu, C; Liu, G; Lu, Z; Luo, Y; Ma, W; Peng, J; Wang, M; Zheng, Q1

Reviews

4 review(s) available for antineoplaston a10 and 2-piperidone

ArticleYear
[Antineoplastons--structure, chemical properties and mechanism of activity].
    Postepy higieny i medycyny doswiadczalnej, 1992, Volume: 46, Issue:6

    Topics: Animals; Benzeneacetamides; Humans; Piperidones

1992
'Antineoplastons'. An unproved cancer therapy.
    JAMA, 1992, Jun-03, Volume: 267, Issue:21

    Topics: Benzeneacetamides; Humans; Neoplasms; Peptides; Piperidines; Piperidones

1992
Potential of antineoplastons in diseases of old age.
    Drugs & aging, 1995, Volume: 7, Issue:3

    Topics: Aged; Aging; Animals; Antineoplastic Agents; Benzeneacetamides; Drug Combinations; Glutamine; Growth Inhibitors; Humans; Neoplasms; Peptides; Phenylacetates; Piperidones

1995
The roles and expression of HOXA/Hoxa10 gene: A prospective marker of mammalian female fertility?
    Reproductive biology, 2022, Volume: 22, Issue:2

    Topics: Animals; Benzeneacetamides; Endometrium; Female; Fertility; Homeobox A10 Proteins; Homeodomain Proteins; Mammals; Piperidones; Prospective Studies; Swine

2022

Trials

10 trial(s) available for antineoplaston a10 and 2-piperidone

ArticleYear
Toxicological study on antineoplastons A-10 and AS2-1 in cancer patients.
    The Kurume medical journal, 1995, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Child; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Phenylacetates; Piperidones

1995
Phase II study of antineoplastons A10 (NSC 648539) and AS2-1 (NSC 620261) in patients with recurrent glioma.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:2

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Confusion; Disorders of Excessive Somnolence; Drug Administration Schedule; Drug Combinations; Female; Glioblastoma; Glutamine; Humans; Injections, Intravenous; Male; Middle Aged; Patient Selection; Phenylacetates; Piperidones; Seizures; Severity of Illness Index; Treatment Outcome

1999
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report.
    Drugs in R&D, 2003, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Cerebral Angiography; Child; Drug Combinations; Glioma; Glutamine; Humans; Karnofsky Performance Status; Phenylacetates; Piperidones; Risk Assessment; Time Factors

2003
Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma : a preliminary report.
    Drugs in R&D, 2004, Volume: 5, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Glioma; Glutamine; Humans; Infant; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2004
Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1.
    Integrative cancer therapies, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Benzeneacetamides; Brain Neoplasms; Child, Preschool; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Glutamine; Humans; Infant; Male; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2005
Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.
    Integrative cancer therapies, 2006, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Glioma; Glutamine; Humans; Injections, Intravenous; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasm Staging; Phenylacetates; Piperidones; Risk Assessment; Survival Analysis; Treatment Outcome

2006
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Survival Rate

2014
Commentary: The response and survival of children with recurrent diffuse intrisic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma, by Burzynski G, et al.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Biomedical Research; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Prognosis; Survival Rate; Treatment Outcome

2014
Main editor's comment to the paper: the response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma. Stanislaw R. Burzynski, Tomasz J. Janicki
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Survival Rate; Treatment Outcome

2014
Randomized phase II study of 5-fluorouracil hepatic arterial infusion with or without antineoplastons as an adjuvant therapy after hepatectomy for liver metastases from colorectal cancer.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Glutamine; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2015

Other Studies

69 other study(ies) available for antineoplaston a10 and 2-piperidone

ArticleYear
The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis-diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:5

    Topics: alpha-Fetoproteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Carcinoma, Hepatocellular; Cell Division; Cisplatin; Dose-Response Relationship, Drug; Humans; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Piperidones; Tumor Cells, Cultured

1992
3-phenylacetylamino-2,6-piperidinedione inhibition of rat Nb2 lymphoma cell mitogenesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 197, Issue:4

    Topics: Animals; Benzeneacetamides; Cell Division; Chromium; DNA; Interleukin-2; Lymphocytes; Mitogens; Molecular Structure; Piperidones; Prolactin; Rats; Tumor Cells, Cultured

1991
Theoretical investigations on the structure and potential binding sites of antineoplaston A10 and experimental findings.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:7

    Topics: Antineoplastic Agents; Benzeneacetamides; Binding Sites; Mathematical Computing; Models, Molecular; Molecular Conformation; Molecular Structure; Piperidines; Piperidones

1990
Pharmacokinetic study of radioactive antineoplaston A10 in rats and mice.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Male; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Tissue Distribution

1990
Studies of the release rate and bioavailability of antineoplaston A10 capsule.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzeneacetamides; Biological Availability; Capsules; Injections, Intravenous; Piperidines; Piperidones; Rabbits

1990
The anticancer effect of antineoplaston A-10 on human breast cancer serially transplanted to athymic mice.
    Nihon Gan Chiryo Gakkai shi, 1990, Jan-20, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Piperidines; Piperidones; Transplantation, Heterologous

1990
Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines. The members of Antineoplaston Study Group.
    The Kurume medical journal, 1990, Volume: 37, Issue:2

    Topics: Administration, Oral; Animals; Benzeneacetamides; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Piperidines; Piperidones; Transplantation, Heterologous; Tumor Cells, Cultured

1990
Actions of an endogenous antitumorigenic agent on mammary tumor development and modeling analysis of its capacity for interacting with DNA.
    Journal of steroid biochemistry, 1988, Volume: 30, Issue:1-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzeneacetamides; DNA, Neoplasm; Female; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Orchiectomy; Piperidines; Piperidones; Rats; Tamoxifen

1988
Chemopreventive effect of antineoplaston A-10 on urethane-induced pulmonary neoplasm in mice.
    Nihon Gan Chiryo Gakkai shi, 1988, Jul-20, Volume: 23, Issue:7

    Topics: Adenoma; Animals; Benzeneacetamides; Female; Lung Neoplasms; Mice; Piperidines; Piperidones; Urethane

1988
Pharmacokinetic study of radioactive antineoplaston A10 following oral administration in rats.
    Drugs under experimental and clinical research, 1987, Volume: 13 Suppl 1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzeneacetamides; Feces; Kinetics; Male; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Tissue Distribution

1987
Chemoprevention by antineoplaston A10 of benzo(a)pyrene-induced pulmonary neoplasia.
    Drugs under experimental and clinical research, 1987, Volume: 13 Suppl 1

    Topics: Adenoma; Animals; Antineoplastic Agents; Benzeneacetamides; Benzo(a)pyrene; Body Weight; Female; Lung Neoplasms; Mice; Mice, Inbred A; Piperidines; Piperidones

1987
Chemo-surveillance: a novel concept of the natural defence mechanism against cancer.
    Drugs under experimental and clinical research, 1987, Volume: 13 Suppl 1

    Topics: Antineoplastic Agents; Benzeneacetamides; Humans; Neoplasms; Peptides; Piperidines; Piperidones

1987
Stereochemical modelling studies of the interaction of antineoplaston A10 with DNA.
    Drugs under experimental and clinical research, 1987, Volume: 13 Suppl 1

    Topics: Antineoplastic Agents; Benzeneacetamides; Chemical Phenomena; Chemistry, Physical; DNA; Humans; Models, Chemical; Molecular Conformation; Piperidines; Piperidones

1987
Inhibition of spontaneous mouse mammary tumour development by antineoplaston A10.
    Drugs under experimental and clinical research, 1987, Volume: 13 Suppl 1

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Female; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Orchiectomy; Piperidines; Piperidones

1987
The effect of Antineoplaston, a new antitumor agent on malignant brain tumors.
    The Kurume medical journal, 1995, Volume: 42, Issue:3

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Child; Drug Combinations; Female; Glioblastoma; Glioma; Glutamine; Humans; Male; Medulloblastoma; Middle Aged; Phenylacetates; Piperidones

1995
Antiestrogenic piperidinediones designed prospectively using computer graphics and energy calculations of DNA-ligand complexes.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:5-6

    Topics: Benzeneacetamides; Breast Neoplasms; Computer-Aided Design; DNA, Neoplasm; Drug Design; Estrogen Antagonists; Humans; Ligands; Piperidones; Thermodynamics; Tumor Cells, Cultured

1994
Inhibition of estrogen stimulated mitogenesis by 3-phenylacetylamino-2,6-piperidinedione and its para-hydroxy analog.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 46, Issue:4

    Topics: Animals; Benzeneacetamides; Binding, Competitive; Cell Division; Cell Nucleus; Cytosol; Estrogen Antagonists; Female; Growth Inhibitors; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Piperidones; Receptors, Estrogen; Receptors, Progesterone; Structure-Activity Relationship; Tumor Cells, Cultured

1993
Inhibitory effect of antineoplaston A10 and AS2-1 on human hepatocellular carcinoma.
    The Kurume medical journal, 1996, Volume: 43, Issue:2

    Topics: Antineoplastic Agents; Benzeneacetamides; Carcinoma, Hepatocellular; Drug Combinations; Glutamine; Humans; Liver Neoplasms; Phenylacetates; Piperidones; Tumor Cells, Cultured

1996
3-[(Phenylacetyl)amino]-2,6-piperidinedione hydrolysis studies with improved synthesis and characterization of hydrolysates.
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:10

    Topics: Antineoplastic Agents; Benzeneacetamides; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Piperidones; Reference Standards

1996
Enantioseparation of 3-phenylacetylamino-2,6-piperidinedione and related chiral compounds.
    Journal of chromatography. A, 1996, Nov-01, Volume: 752, Issue:1-2

    Topics: Benzeneacetamides; Chromatography, High Pressure Liquid; Piperidones; Spectrophotometry, Ultraviolet; Stereoisomerism

1996
Synthesis of antineoplaston A10 analogs as potential antitumor agents.
    Archives of pharmacal research, 1998, Volume: 21, Issue:2

    Topics: Antineoplastic Agents; Benzeneacetamides; Drug Screening Assays, Antitumor; Humans; Hydrogenation; Piperidones; Structure-Activity Relationship; Tumor Cells, Cultured

1998
Synthesis of Mannich bases of antineoplaston A10 and their antitumor activity.
    Archives of pharmacal research, 1994, Volume: 17, Issue:6

    Topics: Antineoplastic Agents; Benzeneacetamides; Drug Screening Assays, Antitumor; Humans; Mannich Bases; Piperidones; Tumor Cells, Cultured

1994
Efficacy of antineoplastons A10 and AS2-1.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:6

    Topics: Antineoplastic Agents; Benzeneacetamides; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Glioma; Glutamine; Humans; National Institutes of Health (U.S.); Phenylacetates; Piperidones; Treatment Failure; United States

1999
Potential utility of antineoplaston A-10 levels in breast cancer.
    Cancer letters, 2000, Jul-03, Volume: 155, Issue:1

    Topics: Adult; Aged; Benzeneacetamides; Breast Neoplasms; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Humans; Middle Aged; Peptides; Piperidones; Risk

2000
Immune modulatory potentials of antineoplaston A-10 in breast cancer patients.
    Cancer letters, 2000, Aug-31, Volume: 157, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; Apoptosis; Benzeneacetamides; Breast Neoplasms; Cells, Cultured; DNA Fragmentation; Female; Humans; Middle Aged; Neutrophils; Piperidones

2000
Novel piperidinedione analogs as inhibitors of breast cancer cell growth.
    Archiv der Pharmazie, 2000, Volume: 333, Issue:12

    Topics: Adjuvants, Immunologic; Antineoplastic Agents; Benzeneacetamides; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Piperidones; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Long-term survival following treatment with antineoplastons for colon cancer with unresectable multiple liver metastases: report of a case.
    Surgery today, 2003, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Aged; Benzeneacetamides; Colectomy; Colonic Neoplasms; Combined Modality Therapy; Electrocoagulation; Humans; Liver Neoplasms; Male; Microwaves; Piperidones; Prognosis; Survivors

2003
A 10-curie Co60 telegamma unit; preliminary report.
    Acta radiologica, 1952, Volume: 38, Issue:2

    Topics: Benzeneacetamides; Cobalt; Cobalt Radioisotopes; Piperidones; Radioactivity

1952
[Action of carbohydrates and related compound on human isohemagglutinins beta(A10) and alpha(BO)].
    Bulletin de la Societe de chimie biologique, 1958, Volume: 40, Issue:5-6

    Topics: Antibodies; Benzeneacetamides; Carbohydrates; Hemagglutinins; Humans; Piperidones

1958
A comparison of the growth properties of Coxsackie virus strains A-9 and A-10 with poliovirus strain Mahoney in cultures of primary human amnion cells.
    Journal of immunology (Baltimore, Md. : 1950), 1961, Volume: 86

    Topics: Amnion; Benzeneacetamides; Coxsackievirus Infections; Enterovirus; Piperidones; Poliomyelitis; Poliovirus; Viruses

1961
Adaptation of Coxsackie virus strain A-10 to human amnion cells in tissue culture.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 105

    Topics: Acclimatization; Adaptation, Physiological; Amnion; Benzeneacetamides; Coxsackievirus Infections; Enterovirus; Piperidones; Tissue Culture Techniques

1960
[ON THE USE OF A 10 PER CENT SOLUTION OF SODIUM CHLORIDE IN DUODENAL INTUBATION].
    Laboratornoe delo, 1963, Volume: 39

    Topics: Benzeneacetamides; Duodenum; Humans; Intubation; Intubation, Gastrointestinal; Pharmaceutical Solutions; Piperidones; Sodium Chloride; Solutions

1963
[SEPSIS ASPERGILLOSA IN A 10-MONTH OLD GIRL].
    Munchener medizinische Wochenschrift (1950), 1963, Oct-18, Volume: 105

    Topics: Aspergillosis; Benzeneacetamides; Female; Fungi; Humans; Infant; Lung Diseases, Fungal; Piperidones; Sepsis

1963
[REANIMATION OF AN 8-DAY-OLD CHILD AFTER A 10 MINUTE PERIOD OF CLINICAL DEATH].
    Khirurgiia, 1963, Volume: 39

    Topics: Benzeneacetamides; Cellulitis; Child; Death; Heart Arrest; Heart Massage; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Piperidones; Resuscitation

1963
[EFFECT OF IONIZING RAYS OF MITOSIS IN MALIGNANT AND BENIGN EPIDERMAL HYPERPLASIA IN MICE. V. EFFECT OF A SINGLE CONTACT IRRADIATION FOLLOWING A 10-DAY PERIOD OF PRETREATMENT WITH CARCINOGENS OR TUMOR-INDUCING AGENTS].
    Strahlentherapie, 1963, Volume: 122

    Topics: Benz(a)Anthracenes; Benzeneacetamides; Carcinogens; Cell Division; Hyperplasia; Hypertrophy; Mice; Mitosis; Neoplasms; Piperidones; Radiation Effects; Research; Skin; Skin Neoplasms; Strontium Isotopes; Surface-Active Agents; Toxicology; Yttrium Isotopes

1963
[THE SIZE OF THE DOG BRAIN BEFORE AND AFTER ITS FIXATION BY MEANS OF PERFUSION OF A 10 PER CENT FORMALIN SOLUTION].
    Biulleten' eksperimental'noi biologii i meditsiny, 1963, Volume: 56

    Topics: Benzeneacetamides; Brain; Dogs; Formaldehyde; Histological Techniques; Perfusion; Pharmaceutical Solutions; Piperidones; Research

1963
[CASE OF NAILING OF A LEG FRACTURE IN A 10-DAY-OLD INFANT].
    Hellenike iatrike, 1964, Volume: 33

    Topics: Benzeneacetamides; Birth Injuries; Femoral Fractures; Fracture Fixation; Fracture Fixation, Intramedullary; Fractures, Bone; Humans; Leg; Piperidones

1964
[MULTIPLE PROGRESSIVE OSSIFYING MYOSITIS IN A 10 MONTH OLD INFANT].
    Voprosy okhrany materinstva i detstva, 1964, Volume: 9

    Topics: Benzeneacetamides; Humans; Infant; Myositis Ossificans; Pathology; Piperidones

1964
[RADIUM TREATED BOTRYOID SARCOMA OF THE VAGINA IN A 10-MONTH OLD GIRL].
    Nederlandsch tijdschrift voor verloskunde en gynaecologie, 1965, Volume: 64

    Topics: Benzeneacetamides; Female; Humans; Infant; Mesenchymoma; Neoplasms; Piperidones; Radium; Rhabdomyosarcoma, Embryonal; Vaginal Neoplasms

1965
A 10 curie strontium 90 beta-ray therapy unit.
    The British journal of radiology, 1960, Volume: 33

    Topics: Benzeneacetamides; Beta Particles; Equipment and Supplies; Piperidones; Radioactivity; Radiotherapy; Strontium; Strontium Radioisotopes

1960
Some physical and chemical properties of Coxsackie viruses A9 and A10.
    Virology, 1962, Volume: 17

    Topics: Benzeneacetamides; Enterovirus; Enterovirus B, Human; Piperidones

1962
A 10-minute check for your 1961 tax return.
    GP, 1962, Volume: 25

    Topics: Benzeneacetamides; Humans; Income Tax; Piperidones

1962
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured

2003
Managing social conflict in complementary and alternative medicine research: the case of antineoplastons.
    Integrative cancer therapies, 2004, Volume: 3, Issue:1

    Topics: Benzeneacetamides; Brain Neoplasms; Clinical Trials, Phase II as Topic; Communication; Complementary Therapies; Conflict of Interest; Documentation; Drug Combinations; Glutamine; Humans; Interprofessional Relations; Phenylacetates; Physician's Role; Piperidones; Power, Psychological; Problem Solving; Social Conditions; Trust

2004
Long-term survival and complete response of a patient with recurrent diffuse intrinsic brain stem glioblastoma multiforme.
    Integrative cancer therapies, 2004, Volume: 3, Issue:3

    Topics: Adult; Benzeneacetamides; Brain Stem Neoplasms; Disease-Free Survival; Drug Combinations; Glioblastoma; Glutamine; Health Status; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Survival Analysis; Time Factors; Treatment Outcome

2004
Antineoplaston induces G(1) arrest by PKCalpha and MAPK pathway in SKBR-3 breast cancer cells.
    Oncology reports, 2005, Volume: 14, Issue:2

    Topics: Benzeneacetamides; Blotting, Western; Breast Neoplasms; Carbazoles; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G1 Phase; Humans; Indoles; Isoenzymes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Piperidones; Protein Kinase C; Protein Kinase C-alpha; Retinoblastoma Protein; Time Factors; Tumor Suppressor Proteins

2005
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Feb-19, Volume: 105, Issue:7

    Topics: Animals; Benzeneacetamides; Biophysical Phenomena; Biophysics; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Endocytosis; Glycolates; Humans; Lactic Acid; Ligands; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Nanoparticles; Piperidones; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostate-Specific Antigen; Surface Properties; Xenograft Model Antitumor Assays

2008
A light-driven anti-cancer dual-therapeutic cassette enhances solid tumour regression.
    Advanced healthcare materials, 2013, Volume: 2, Issue:9

    Topics: Animals; Antibiotics, Antineoplastic; Benzeneacetamides; Cell Line; Cell Survival; DNA; Doxorubicin; Drug Design; Gold; Humans; Hyperthermia, Induced; Light; Male; Metal Nanoparticles; Mice; Mice, Nude; Nanoparticles; Piperidones; Prostatic Neoplasms; RNA; Transplantation, Heterologous

2013
Targeted delivery of Epirubicin to cancer cells by PEGylated A10 aptamer.
    Journal of drug targeting, 2013, Volume: 21, Issue:8

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Aptamers, Nucleotide; Benzeneacetamides; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Epirubicin; Humans; Male; Piperidones; Polyethylene Glycols; Prostatic Neoplasms

2013
Complete response and long-term survival (>20 years) of a child with tectal glioma: a case report.
    Pediatric neurosurgery, 2015, Volume: 50, Issue:2

    Topics: Adolescent; Benzeneacetamides; Brain Neoplasms; Drug Combinations; Follow-Up Studies; Glioma; Glutamine; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Treatment Outcome

2015
[Molecular epidemiology of hand-foot-mouth disease associated pathogen Coxsackievirus A10 identified in Fujian province, 2011-2014].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2016, Volume: 37, Issue:4

    Topics: Benzeneacetamides; Child; Child, Preschool; China; Enterovirus A, Human; Epidemics; Female; Hand, Foot and Mouth Disease; Humans; Infant; Male; Molecular Epidemiology; Molecular Sequence Data; Open Reading Frames; Phylogeny; Piperidones; Serogroup

2016
Design and development of microemulsion systems of a new antineoplaston A10 analog for enhanced intravenous antitumor activity: In vitro characterization, molecular docking,
    International journal of pharmaceutics, 2018, Jul-10, Volume: 545, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Drug Compounding; Emulsions; Ethanol; Female; Histone Deacetylases; Humans; Injections, Intravenous; Iodine Radioisotopes; Male; MCF-7 Cells; Microscopy, Electron, Transmission; Molecular Docking Simulation; Piperidones; Polysorbates; Rabbits; Repressor Proteins; Technology, Pharmaceutical; Tissue Distribution

2018
Improved Targeting and Tumor Retention of a Newly Synthesized Antineoplaston A10 Derivative by Intratumoral Administration: Molecular Docking, Technetium 99m Radiolabeling, and In Vivo Biodistribution Studies.
    Cancer biotherapy & radiopharmaceuticals, 2018, Volume: 33, Issue:6

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Breast Neoplasms; Cell Line, Tumor; Drug Delivery Systems; Drug Screening Assays, Antitumor; Emulsions; Female; Humans; Injections, Intralesional; Injections, Intravenous; Mice; Molecular Docking Simulation; Particle Size; Piperidones; Technetium; Tissue Distribution; Xenograft Model Antitumor Assays

2018
Epithelial cell adhesion efficacy of a novel peptide identified by panning on a smooth titanium surface.
    International journal of oral science, 2018, 07-02, Volume: 10, Issue:3

    Topics: Amino Acid Sequence; Animals; Benzeneacetamides; Cattle; Cell Adhesion; Cell Movement; Cells, Cultured; Cytokines; Dental Implants; Enzyme-Linked Immunosorbent Assay; Epithelial Attachment; Epithelial Cells; Microscopy, Confocal; Microscopy, Electron, Scanning; Piperidones; Platelet-Rich Plasma; Receptors, Thrombin; Surface Properties; Titanium

2018
Development of a pseudovirus-based assay for measuring neutralizing antibodies against Coxsackievirus A10.
    Human vaccines & immunotherapeutics, 2020, 06-02, Volume: 16, Issue:6

    Topics: Antibodies, Neutralizing; Benzeneacetamides; Child; Enterovirus A, Human; Hand, Foot and Mouth Disease; Humans; Piperidones; Vaccination

2020
[Modified version of the PCAT-A10 tool for the evaluation of primary care].
    Atencion primaria, 2021, Volume: 53, Issue:1

    Topics: Adult; Benzeneacetamides; Cross-Sectional Studies; Humans; Piperidones; Primary Health Care; Psychometrics; Reproducibility of Results; Surveys and Questionnaires

2021
Transposon insertions within alleles of BnaFLC.A10 and BnaFLC.A2 are associated with seasonal crop type in rapeseed.
    Journal of experimental botany, 2020, 08-06, Volume: 71, Issue:16

    Topics: Alleles; Benzeneacetamides; Brassica napus; Flowers; Gene Expression Regulation, Plant; Piperidones; Seasons

2020
Protective effect of transient receptor potential melastatin 2 inhibitor A10 on oxygen glucose deprivation/reperfusion model.
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2021, 02-25, Volume: 50, Issue:1

    Topics: Apoptosis; Benzeneacetamides; Cell Survival; Glucose; Humans; Oxygen; Piperidones; Reactive Oxygen Species; Reperfusion; TRPM Cation Channels

2021
Substitution of ROTEM FIBTEM A5 for A10 in trauma: an observational study building a case for more rapid analysis of coagulopathy.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:2

    Topics: Benzeneacetamides; Blood Coagulation Disorders; Fibrinogen; Humans; Piperidones; Retrospective Studies; Thrombelastography

2022
Genomic surveillance of coxsackievirus A10 reveals genetic features and recent appearance of genogroup D in Shanghai, China, 2016-2020.
    Virologica Sinica, 2022, Volume: 37, Issue:2

    Topics: Benzeneacetamides; China; Enterovirus; Genomics; Genotype; Hand, Foot and Mouth Disease; Humans; Phylogeny; Piperidones

2022
Isolation of bacterial strains from compost teas and screening of their PGPR properties on potato plants.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:50

    Topics: Achromobacter; Bacteria; Benzeneacetamides; Cadmium; Coffee; Composting; Fertilizers; Industrial Waste; Pesticides; Phylogeny; Piperidones; Siderophores; Soil; Soil Microbiology; Solanum tuberosum; Tea; Wastewater

2022
Unbiased Stereological Estimates of Dopaminergic and GABAergic Neurons in the A10, A9, and A8 Subregions in the Young Male Macaque.
    Neuroscience, 2022, 08-01, Volume: 496

    Topics: Animals; Benzeneacetamides; Dopamine; Dopaminergic Neurons; GABAergic Neurons; gamma-Aminobutyric Acid; Macaca; Male; Mesencephalon; Piperidones; Substantia Nigra

2022
Pathogenic analysis of coxsackievirus A10 in rhesus macaques.
    Virologica Sinica, 2022, Volume: 37, Issue:4

    Topics: Animals; Antibodies, Neutralizing; Benzeneacetamides; Child, Preschool; Enterovirus A, Human; Hand, Foot and Mouth Disease; Humans; Macaca mulatta; Piperidones

2022
Structural insights into engineering a T-cell receptor targeting MAGE-A10 with higher affinity and specificity for cancer immunotherapy.
    Journal for immunotherapy of cancer, 2022, Volume: 10, Issue:7

    Topics: Benzeneacetamides; Humans; Immunotherapy; Melanoma; Peptides; Piperidones; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta

2022
Comprehensive profiling and characterization of cellular microRNAs in response to coxsackievirus A10 infection in bronchial epithelial cells.
    Virology journal, 2022, 07-21, Volume: 19, Issue:1

    Topics: Benzeneacetamides; Enterovirus A, Human; Epithelial Cells; Hand, Foot and Mouth Disease; Humans; MicroRNAs; Piperidones

2022
Complete Genome Sequence Data of a Newly Isolated
    Plant disease, 2022, Volume: 106, Issue:9

    Topics: Benzeneacetamides; Biological Control Agents; Oomycetes; Piperidones; Streptomyces

2022
A conserved HSF:miR169:NF-YA loop involved in tomato and Arabidopsis heat stress tolerance.
    The Plant journal : for cell and molecular biology, 2022, Volume: 112, Issue:1

    Topics: Arabidopsis; Arabidopsis Proteins; Benzeneacetamides; CCAAT-Binding Factor; Gene Expression Regulation, Plant; Heat Shock Transcription Factors; MicroRNAs; Piperidones; Plant Proteins; Plants, Genetically Modified; Solanum lycopersicum; Stress, Physiological; Thermotolerance; Transcription Factors

2022
Kaolin activation of recalcified citrated whole blood in a point-of-care viscoelastic coagulation test.
    Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2022, Volume: 86, Issue:4

    Topics: Animals; Benzeneacetamides; Blood Coagulation; Blood Coagulation Tests; Citrates; Citric Acid; Dogs; Kaolin; Piperidones; Point-of-Care Systems; Thrombelastography

2022
The spatial-temporal distribution and etiological characteristics of hand-foot-and-mouth disease before and after EV‑A71 vaccination in Kunming, China, 2017-2020.
    Scientific reports, 2022, 10-11, Volume: 12, Issue:1

    Topics: Animals; Antibodies, Viral; Antigens, Viral; Benzeneacetamides; Child; China; Enterovirus; Enterovirus A, Human; Enterovirus Infections; Foot-and-Mouth Disease; Hand, Foot and Mouth Disease; Humans; Infant; Piperidones; Serogroup; Vaccination; Vaccines, Combined

2022