antimycin and butenolide

antimycin has been researched along with butenolide* in 2 studies

Other Studies

2 other study(ies) available for antimycin and butenolide

ArticleYear
Donor-acceptor substituted cyclopropane to butanolide and butenolide natural products: enantiospecific first total synthesis of (+)-hydroxyancepsenolide.
    Organic letters, 2014, Dec-19, Volume: 16, Issue:24

    An oxygen substituted donor-acceptor cyclopropane (DAC) is used as a common intermediate in the enantiospecific collective total synthesis of butanolide- and butenolide-based natural products like (+)-juruenolide C and D, (+)-blastmycinone, (+)-antimycinone, and (+)-ancepsenolide. Enantiospecific first total syntheses of (+)-hydroxyancepsenolide and its acetate are achieved confirming their absolute stereochemistry.

    Topics: 4-Butyrolactone; Antimycin A; Biological Products; Cyclopropanes; Dioxoles; Lactones; Molecular Structure; Stereoisomerism

2014
Volatile lactones from streptomycetes arise via the antimycin biosynthetic pathway.
    Chembiochem : a European journal of chemical biology, 2012, Jul-23, Volume: 13, Issue:11

    The volatiles released by several streptomycetes were collected by using a closed-loop stripping apparatus (CLSA) and analysed by GC-MS. The obtained headspace extracts of various species contained blastmycinone, a known degradation product of the fungicidal antibiotic, antimycin A(3b), and several unknown derivatives. The suggested structures of these compounds, based on their mass spectra and GC retention indices, were confirmed by comparison to synthetic reference samples. Additional compounds found in the headspace extracts were butenolides formed from the blastmycinones by elimination of the carboxylic acid moiety. Analysis of a gene knockout mutant in the antimycin biosynthetic gene cluster demonstrated that all blastmycinones and butenolides are formed via the antimycin biosynthetic pathway. The structural variation of the blastmycinones identified here is much larger than within the known antimycins, thus suggesting that several antimycin derivatives remain to be discovered.

    Topics: 4-Butyrolactone; Antimycin A; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Streptomyces

2012